The role of surgical factors eliciting oculocardiac reflex of patients undergoing orbital tumor surgery: a retrospective study
Springer Science and Business Media LLC - Trang 1-9 - 2023
Tóm tắt
Orbital tumors are an interdisciplinary disease, and surgery is one of the main treatment methods. The oculocardiac reflex (OCR) is a condition of surgery for orbital tumors. The aim of this study was to investigate whether there is an association between many surgical factors and the incidence of OCR in orbital tumor surgery. Comparisons were made between patients with and without OCR using the Mann–Whitney test, Fisher’s exact test, and Chi-square test. When comparing multiple groups (groups > 2), to explain which two groups had differences, post hoc testing was used for analysis, and the differences between groups were judged according to the adjusted standardized residuals. The results showed that the incidence of intraoperative OCR was different based on the different exposed operative field locations (p = 0.021). The OCR incidence in those with lesions involving the orbital apex and lesions adhering to extraocular muscles was higher than that of others (p < 0.001 and p = 0.003). In addition, multivariate logistic regression analysis revealed that orbital apex involvement and extraocular muscle adhesion were highly associated with a higher incidence of OCR (p < 0.001 and p = 0.013), while the operative field located in the lateral-superior orbit was highly associated with a lower incidence of OCR (p = 0.029). In orbital tumor surgery under general anesthesia, lesions involving the orbital apex and lesion adhesion to the extraocular muscles were independent risk factors for OCR, and an operative field located in the lateral-superior orbit was a protective factor for OCR.
Tài liệu tham khảo
Rokohl AC, Koch KR, Kabbasch C et al (2019) Importance of interdisciplinary collaboration for optimal treatment of orbital tumors. HNO 67:528–533
Ponto KA, Brockmann MA, Koutsimpelas D et al (2021) Excisional surgery of orbital tumors. Ophthalmologe 118:995–1003
Shields JA, Shields CL, Scartozzi R (2004) Survey of 1264 patients with orbital tumors and simulating lesions: the 2002 Montgomery Lecture, part 1. Ophthalmology 111:997–1008
Dandekar P, Mohan S, Baranwal V (2021) Oculocardiac reflex in phacoemulsification: peribulbar vs topical anesthesia. Indian J Ophthalmol 69:923–926
Ha SG, Huh J, Lee BR et al (2018) Surgical factors affecting oculocardiac reflex during strabismus surgery. BMC Ophthalmol 18:103
Hunyor AP (1994) Reflexes and the eye. Aust N Z J Ophthalmol 22:155–159
Braun U, Feise J, Mühlendyck H (1993) Is there a cholinergic and an adrenergic phase of the oculocardiac reflex during strabismus surgery? Acta Anaesthesiol Scand 37:390–395
Lang SA, Van der Wal M (1994) Death from the oculocardiac reflex. Can J Anaesth 41:161
Hahnenkamp K, Hönemann CW, Fischer LG et al (2000) Effect of different anaesthetic regimes on the oculocardiac reflex during paediatric strabismus surgery. Paediatr Anaesth 10:601–608
Aletaha M, Bagheri A, Roodneshin F et al (2016) Oculocardiac reflex during strabismus surgery: experience from a tertiary hospital. Strabismus 24:74–78
Lai YH, Hsu HT, Wang HZ et al (2014) The oculocardiac reflex during strabismus surgery: its relationship to preoperative clinical eye findings and subsequent postoperative emesis. J aapos 18:151–155
Song J, Liu S, Fan B et al (2021) Perioperative dexmedetomidine reduces emergence agitation without increasing the oculocardiac reflex in children: a systematic review and meta-analysis. Medicine (Baltimore) 100:e25717
Westerling D, Blohmé J, Stigmar G (1998) Orbital mass in a child causing somnolence, nausea and bradycardia. Can J Anaesth 45:777–780
Paciuc-Beja M, Meizner-Grezemkovsky D, Paciuc M et al (2020) Oculocardiac reflex during intravitreal injection. Med Hypothesis Discov Innov Ophthalmol 9:111–117
Buck LS, Stockton S, Spankovich C et al (2020) Pediatric orbital floor fractures and the oculocardiac reflex: Experience from a level I trauma center. Am J Otolaryngol 41:102553
Defalque RJ (1969) Retrobulbar block for oculocardiac reflex: duration of protection by common local anesthetics. Acta Ophthalmol 47:998–1003
Klockgether-Radke A, Demmel C, Braun U et al (1993) Emesis and the oculocardiac reflex. Drug prophylaxis with droperidol and atropine in children undergoing strabismus surgery. Anaesthesist 42:356–360
Tramèr MR, Sansonetti A, Fuchs-Buder T et al (1998) Oculocardiac reflex and postoperative vomiting in paediatric strabismus surgery. A randomised controlled trial comparing four anaesthetic techniques. Acta Anaesthesiol Scand 42:117–123
Lemaître S, Arora AK (2021) Use of adjuvant sub-Tenon’s anaesthesia in reducing the incidence of oculocardiac reflex and postoperative pain in primary enucleations for uveal melanoma. Anaesth Crit Care Pain Med 40:100835
Arnold RW, Rinner AR, Arnold AW et al (2020) The impact of re-operation, relatives and race on the oculocardiac reflex during strabismus surgery. Clin Ophthalmol 14:4253–4261
Zimbelmann M, Neppert B, Piria R et al (2021) Treatment and management of orbital tumors. Ophthalmologe 118:1004–1011
Tailor TD, Gupta D, Dalley RW et al (2013) Orbital neoplasms in adults: clinical, radiologic, and pathologic review. Radiographics 33:1739–1758
Garrity JA, Yeatts RP (1984) The oculocardiac reflex with an orbital tumor. Am J Ophthalmol 98:818
Allen LE, Sudesh S, Sandramouli S et al (1998) The association between the oculocardiac reflex and post-operative vomiting in children undergoing strabismus surgery. Eye (Lond) 12(Pt 2):193–196
Kılıç Y, Güleç MS (2021) The association between surgical technique and oculocardiac reflex in pediatric strabismus surgery: an observational study. Braz J Anesthesiol 71:623–627
Arnold RW (2021) The oculocardiac reflex: a review. Clin Ophthalmol 15:2693–2725
Min SW, Hwang JM (2011) Adjustment in patients with asystole during strabismus surgery. Graefes Arch Clin Exp Ophthalmol 249:1889–1892
Steib A, Karcenty A, Calache E et al (2005) Effects of subtenon anesthesia combined with general anesthesia on perioperative analgesic requirements in pediatric strabismus surgery. Reg Anesth Pain Med 30:478–483
Karaman T, Demir S, Dogru S et al (2016) The effect of anesthesia depth on the oculocardiac reflex in strabismus surgery. J Clin Monit Comput 30:889–893
Choi SH, Lee SJ, Kim SH et al (2007) Single bolus of intravenous ketamine for anesthetic induction decreases oculocardiac reflex in children undergoing strabismus surgery. Acta Anaesthesiol Scand 51:759–762
Ohashi T, Kase M, Yokoi M (1986) Quantitative analysis of the oculocardiac reflex by traction on human extraocular muscle. Invest Ophthalmol Vis Sci 27:1160–1164
Shin SY, Kim MJ, Joo J (2020) Oculocardiac reflex and oculorespiratory reflex during strabismus surgery under general anesthesia using the laryngeal mask airway with maintenance of spontaneous respiration: a retrospective study. J Int Med Res 48:300060520945158
Chung CJ, Lee JM, Choi SR et al (2008) Effect of remifentanil on oculocardiac reflex in paediatric strabismus surgery. Acta Anaesthesiol Scand 52:1273–1277
Karanovic N, Jukic M, Carev M et al (2004) Rocuronium attenuates oculocardiac reflex during squint surgery in children anesthetized with halothane and nitrous oxide. Acta Anaesthesiol Scand 48:1301–1305