Role of protein kinase A in phosphorylation of NMDA receptor 1 subunits in dorsal horn and spinothalamic tract neurons after intradermal injection of capsaicin in rats

Neuroscience - Tập 115 - Trang 775-786 - 2002
X Zou1, Q Lin1, W.D Willis1
1Department of Anatomy and Neuroscience, Marine Biomedical Institute, The University of Texas Medical Branch, Galveston, TX 77555-1069, USA

Tài liệu tham khảo

Aanonsen, 1987, Nociceptive action of excitatory amino acids in the mouse: effects of spinally administered opioids, phencyclidine and sigma agonists, J. Pharmacol. Exp. Ther., 243, 9 Aley, 2000, Chronic hypersensitivity for inflammatory nociceptor sensitization mediated by the epsilon isozyme of protein kinase C, J. Neurosci., 20, 4680, 10.1523/JNEUROSCI.20-12-04680.2000 Bardoni, 1998, NMDA EPSCs at glutamatergic synapses in the spinal cord dorsal horn of the postnatal rat, J. Neurosci., 18, 6558, 10.1523/JNEUROSCI.18-16-06558.1998 Cerne, 1992, Cyclic adenosine 3′5′-monophosphate potentiates excitatory amino acid and synaptic responses of rat spinal dorsal horn neurons, Brain Res., 596, 111, 10.1016/0006-8993(92)91538-P Cerne, 1993, Enhancement of the N-methyl-D-aspartate response in spinal dorsal horn neurons by cAMP-dependent protein kinase, Neurosci. Lett., 161, 124, 10.1016/0304-3940(93)90275-P Chen, 1991, Sustained potentiation of NMDA receptor-mediated glutamate responses through activation of protein kinase C by a mu opioid, Neuron, 7, 319, 10.1016/0896-6273(91)90270-A Chen, 1992, Protein kinase C reduces Mg2+ block of NMDA-receptor channels as a mechanism of modulation, Nature, 356, 521, 10.1038/356521a0 Christie, 1999, Insulin causes a transient tyrosine phosphorylation of NR2A and NR2B NMDA receptor subunits in rat hippocampus, J. Neurochem., 72, 1523, 10.1046/j.1471-4159.1999.721523.x Davies, 1987, Evidence for involvement of N-methylaspartate receptors in ‘wind-up’ of class 2 neurones in the dorsal horn of the rat, Brain Res., 424, 402, 10.1016/0006-8993(87)91487-9 Dickenson, 1987, Evidence for a role of the NMDA receptor in the frequency dependent potentiation of deep rat dorsal horn nociceptive neurones following C fibre stimulation, Neuropharmacology, 26, 1235, 10.1016/0028-3908(87)90275-9 Dougherty, 1992, The role of NMDA and non-NMDA excitatory amino acid receptors in the excitation of primate spinothalamic tract neurons by mechanical, chemical, thermal, and electrical stimuli, J. Neurosci., 12, 3025, 10.1523/JNEUROSCI.12-08-03025.1992 Dougherty, 1991, Modification of the responses of primate spinothalamic neurons to mechanical stimulation by excitatory amino acids and an N-methyl-D-aspartate antagonist, Brain Res., 542, 15, 10.1016/0006-8993(91)90991-4 Dougherty, 1992, Enhanced responses of spinothalamic tract neurons to excitatory amino acids accompany capsaicin-induced sensitization in the monkey, J. Neurosci., 12, 883, 10.1523/JNEUROSCI.12-03-00883.1992 Haley, 1990, Evidence for spinal N-methyl-D-aspartate receptor involvement in prolonged chemical nociception in the rat, Brain Res., 518, 218, 10.1016/0006-8993(90)90975-H Hatt, 1999, Modification of glutamate receptor channels: molecular mechanisms and functional consequences, Naturwissenschaften, 86, 177, 10.1007/s001140050593 Hua, 1999, Inhibition of spinal protein kinase C reduces nerve injury-induced tactile allodynia in neuropathic rats, Neurosci. Lett., 276, 99, 10.1016/S0304-3940(99)00818-6 Khan, 1998, Nociceptive and antinociceptive responses to intrathecally administered nicotinic agonists, Neuropharmacology, 37, 1515, 10.1016/S0028-3908(98)00143-9 LaMotte, 1992, Pain, hyperalgesia and activity in nociceptive C units in humans after intradermal injection of capsaicin, J. Physiol., 448, 749, 10.1113/jphysiol.1992.sp019068 LaMotte, 1991, Neurogenic hyperalgesia: psychophysical studies of underlying mechanisms, J. Neurophysiol., 66, 190, 10.1152/jn.1991.66.1.190 Laurie, 1995, The distribution of splice variants of the NMDAR1 subunit mRNA in adult rat brain, Brain Res. Mol. Brain Res., 32, 94, 10.1016/0169-328X(95)00067-3 Leonard, 1997, Cyclic AMP-dependent protein kinase and protein kinase C phosphorylate N-methyl-D-aspartate receptors at different sites, J. Biol. Chem., 272, 12107, 10.1074/jbc.272.18.12107 Lewin, 1999, Cyclic GMP pathway is critical for inducing long-term sensitization of nociceptive sensory neurons, Nat. Neurosci., 2, 18, 10.1038/4520 Li, 1998, Silent glutamatergic synapses and nociception in mammalian spinal cord, Nature, 393, 695, 10.1038/31496 Lin, 1999, Nitric oxide mediates the central sensitization of primate spinothalamic tract neurons, J. Neurophysiol., 81, 1075, 10.1152/jn.1999.81.3.1075 Lin, 1996, Possible role of protein kinase C in the sensitization of primate spinothalamic tract neurons, J. Neurosci., 16, 3026, 10.1523/JNEUROSCI.16-09-03026.1996 Lin, 1997, Involvement of cGMP in nociceptive processing by and sensitization of spinothalamic neurons in primates, J. Neurosci., 17, 3293, 10.1523/JNEUROSCI.17-09-03293.1997 Lin, 2002, Effects of Protein Kinase A activation on the responses of primate spinothalamic tract neurons to mechanical stimuli, J. Neurophysiol., 88, 214, 10.1152/jn.2002.88.1.214 Liu, 1994, Evidence for presynaptic N-methyl-D-aspartate autoreceptors in the spinal cord dorsal horn, Proc. Natl. Acad. Sci. USA, 91, 8383, 10.1073/pnas.91.18.8383 Mammen, 1997, Phosphorylation of the alpha-amino-3-hydroxy-5-methylisoxazole4-propionic acid receptor GluR1 subunit by calcium/calmodulin-dependent kinase II, J. Biol. Chem., 272, 32528, 10.1074/jbc.272.51.32528 Masu, 1993, Molecular characterization of NMDA and metabotropic glutamate receptors, Ann. NY Acad. Sci., 707, 153, 10.1111/j.1749-6632.1993.tb38050.x Mori, 1995, Structure and function of the NMDA receptor channel, Neuropharmacology, 34, 1219, 10.1016/0028-3908(95)00109-J Nagy, 1993, The role of neurokinin and N-methyl-D-aspartate receptors in synaptic transmission from capsaicin-sensitive primary afferents in the rat spinal cord in vitro, Neuroscience, 52, 1029, 10.1016/0306-4522(93)90549-U Narita, 2000, Role of the phosphatidylinositol-specific phospholipase C pathway in delta-opioid receptor-mediated antinociception in the mouse spinal cord, Neuroscience, 99, 327, 10.1016/S0306-4522(00)00202-5 Paxinos, G., Watson, C. 1986. The Rat Brain in Stereotaxic Coordinates. Academic Press, Sydney. Peng, 1997, Involvement of protein kinase C in responses of rat dorsal horn neurons to mechanical stimuli and periaqueductal gray descending inhibition, Exp. Brain Res., 114, 561, 10.1007/PL00005664 Raymond, 1994, Glutamate receptor modulation by protein phosphorylation, J. Physiol. Paris, 88, 181, 10.1016/0928-4257(94)90004-3 Ren, 1993, NMDA receptor antagonists attenuate mechanical hyperalgesia in rats with unilateral inflammation of the hindpaw, Neurosci. Lett., 163, 22, 10.1016/0304-3940(93)90220-F Ren, 1992, The effects of a non-competitive NMDA receptor antagonist, MK-801, on behavioral hyperalgesia and dorsal horn neuronal activity in rats with unilateral inflammation, Pain, 50, 331, 10.1016/0304-3959(92)90039-E Ren, 1992, The intrathecal administration of excitatory amino acid receptor antagonists selectively attenuated carrageenan-induced behavioral hyperalgesia in rats, Eur. J. Pharmacol., 219, 235, 10.1016/0014-2999(92)90301-J Rivot, 1999, Nitric oxide (NO) release by glutamate and NMDA in the dorsal horn of the spinal cord: an in vivo electrochemical approach in the rat, Brain Res., 821, 101, 10.1016/S0006-8993(99)01075-6 Rostas, 1996, Enhanced tyrosine phosphorylation of the 2B subunit of the N-methyl-D-aspartate receptor in long-term potentiation, Proc. Natl. Acad. Sci. USA, 93, 10452, 10.1073/pnas.93.19.10452 Rusin, 1993, Tachykinins potentiate N-methyl-D-aspartate responses in acutely isolated neurons from the dorsal horn, J. Neurochem., 60, 952, 10.1111/j.1471-4159.1993.tb03242.x Simone, 1991, Neurogenic hyperalgesia: central neural correlates in responses of spinothalamic tract neurons, J. Neurophysiol., 66, 228, 10.1152/jn.1991.66.1.228 Sluka, 1994, Differential effects of N-methyl-D-aspartate (NMDA) and non-NMDA receptor antagonists on spinal release of amino acids after development of acute arthritis in rats, Brain Res., 664, 77, 10.1016/0006-8993(94)91956-9 Sluka, 1997, Inhibitors of G-proteins and protein kinases reduce the sensitization to mechanical stimulation and the desensitization to heat of spinothalamic tract neurons induced by intradermal injection of capsaicin in the primate, Exp. Brain Res., 115, 15, 10.1007/PL00005675 Sluka, 1997, The effects of G-protein and protein kinase inhibitors on the behavioral responses of rats to intradermal injection of capsaicin, Pain, 71, 165, 10.1016/S0304-3959(97)03371-X Sluka, 1993, Joint inflammation and hyperalgesia are reduced by spinal bicuculline, NeuroReport, 5, 109, 10.1097/00001756-199311180-00003 Song, 1999, Involvement of NMDA and non-NMDA receptors in transmission of spinal visceral nociception in cat, Zhongguo Yao Li Xue Bao, 20, 308 Sorkin, 1999, Acute pain mechanisms, Surg. Clin. North Am., 79, 213, 10.1016/S0039-6109(05)70380-7 Sugihara, 1992, Structures and properties of seven isoforms of the NMDA receptor generated by alternative splicing, Biochem. Biophys. Res. Commun., 185, 826, 10.1016/0006-291X(92)91701-Q Tingley, 1997, Characterization of protein kinase A and protein kinase C phosphorylation of the N-methyl-D-aspartate receptor NR1 subunit using phosphorylation site-specific antibodies, J. Biol. Chem., 272, 5157, 10.1074/jbc.272.8.5157 Torebjork, 1992, Central changes in processing of mechanoreceptive input in capsaicin-induced secondary hyperalgesia in humans, J. Physiol., 448, 765, 10.1113/jphysiol.1992.sp019069 Tsuda, 1999, in vivo pathway of thermal hyperalgesia by intrathecal administration of alpha, beta-methylene ATP in mouse spinal cord: involvement of the glutamate-NMDA receptor system, Br. J. Pharmacol., 127, 449, 10.1038/sj.bjp.0702582 Vornov, 1994, Delayed protection by MK-801 and tetrodotoxin in a rat organotypic hippocampal culture model of ischemia, Stroke, 25, 457, 10.1161/01.STR.25.2.457 Wang, 1996, Ca(2+)-independent reduction of N-methyl-D-aspartate channel activity by protein tyrosine phosphatase, Proc. Natl. Acad. Sci. USA, 93, 1721, 10.1073/pnas.93.4.1721 Wu, 1998, Changes in nitric oxide synthase isoforms in the spinal cord of rat following induction of chronic arthritis, Exp. Brain Res., 118, 457, 10.1007/s002210050302 Ye, 1996, Ultrastructural localization of glutamate receptor subunits (NMDAR1, AMPA GluR1 and GluR2/3) and spinothalamic tract cells, NeuroReport, 7, 2581, 10.1097/00001756-199611040-00035 Yu, 1997, NMDA channel regulation by channel-associated protein tyrosine kinase Src, Science, 275, 674, 10.1126/science.275.5300.674 Yu, 1999, Src, a molecular switch governing gain control of synaptic transmission mediated by N-methyl-D-aspartate receptors, Proc. Natl. Acad. Sci. USA, 96, 7697, 10.1073/pnas.96.14.7697 Zou, 2000, Enhanced phosphorylation of NMDA receptor 1 subunits in spinal cord dorsal horn and spinothalamic tract neurons after intradermal injection of capsaicin in rats, J. Neurosci., 20, 6989, 10.1523/JNEUROSCI.20-18-06989.2000 Zou, 2001, Role of protein kinase A in phosphorylation of NMDA receptor 1 subunits in dorsal horn and spinothalamic tract neurons after intradermal injection of capsaicin in rats, Soc. Neurosci. Abstr., 27