Brain iron deposits are associated with general cognitive ability and cognitive aging

Baba, 1990, Methodological issues in modeling absence: A comparison of least squares and tobit analyses, J. Appl. Psychol, 75, 428, 10.1037/0021-9010.75.4.428 Bartzokis, 2007, Brain ferritin iron may influence age- and gender-related risks of neurodegeneration, Neurobiol. Aging, 28, 414, 10.1016/j.neurobiolaging.2006.02.005 Brass, 2006, Magnetic resonance imaging of iron deposition in neurological disorders, Top. Magn. Reson. Imaging, 17, 31, 10.1097/01.rmr.0000245459.82782.e4 Casanova, 2003, Mineralization of the basal ganglia: implications for neuropsychiatry, pathology and neuroimaging, Psychiatry Res, 121, 59, 10.1016/S0165-1781(03)00202-6 Cordonnier, 2007, Spontaneous brain microbleeds: systematic review, subgroup analyses and standards for study design and reporting, Brain, 130, 1988, 10.1093/brain/awl387 Cordonnier, 2009, Improving inter-rater agreement about brain microbleeds: development of the Brain Observer Microbleed Scale BOMBS, Stroke, 40, 94, 10.1161/STROKEAHA.108.526996 Crawford, 2001, The NART as an index of prior intellectual functioning: a retrospective validity study covering a 66-year interval, Psychol. Med, 31, 451, 10.1017/S0033291701003634 Deary, 2009, Age-associated cognitive decline, Br. Med. Bull, 92, 135, 10.1093/bmb/ldp033 Deary, 2007, The Lothian Birth Cohort 1936: a study to examine influences on cognitive ageing from age eleven to age seventy and beyond, BMC Geriatr, 7, 28, 10.1186/1471-2318-7-28 Deary, 2010, The neuroscience of human intelligence differences, Nat. Rev. Neurosci, 11, 201, 10.1038/nrn2793 Deary, 2004, The impact of childhood intelligence on later life: Following up the Scottish mental surveys of 1932 and 1947, J. Pers. Soc. Psychol, 86, 130, 10.1037/0022-3514.86.1.130 Folstein, 1975, Mini-mental state, J. Psychiatr. Res, 12, 189, 10.1016/0022-3956(75)90026-6 Floyd, 1976, An adaptive algorithm for spatial grey scale, Proceedings of the Society of Information Display, 17, 75 Frisoni, 2007, The effect of white matter lesions on cognition in the elderly: small but detectable, Nat. Clin. Pract. Neurol, 3, 620, 10.1038/ncpneuro0638 Harder, 2008, Mineralization of the deep gray matter with age: A retrospective review with susceptibility-weighted MR imaging, AJNR Am. J. Neuroradiol, 29, 176, 10.3174/ajnr.A0770 Hedden, 2004, Insights into the ageing mind: A view from cognitive neuroscience, Nat. Rev. Neurosci, 5, 87, 10.1038/nrn1323 Hofer, 2001, Understanding ageing: An evaluation of research designs for assessing the interdependence of ageing-related changes, Gerontology, 47, 341, 10.1159/000052825 Holdnack, 2001 Jenkinson, 2002, Improved optimisation for the robust and accurate linear registration and motion correction of brain images, Neuroimage, 17, 825, 10.1006/nimg.2002.1132 Jensen, 1998 Jung, 2007, The Parieto-Frontal Integration Theory (P-FIT) of intelligence: converging neuroimaging evidence, Behav. Brain Sci, 30, 135, 10.1017/S0140525X07001185 Nelson, 1991 Pujol, 1992, Biological significance of iron-related magnetic resonance imaging changes in the brain, Arch. Neurol, 49, 711, 10.1001/archneur.1992.00530310053012 Salthouse, 2000, Structural constraints on process explanations in cognitive aging, Psychol. Aging, 15, 44, 10.1037/0882-7974.15.1.44 Schipper, 2004, Brain iron deposition and the free radical-mitochondrial theory of ageing, Ageing Res. Rev, 3, 265, 10.1016/j.arr.2004.02.001 1949 Slager, 1956, The incidence, composition and pathological significance of intracerebral vascular deposits in the basal ganglia, J. Neuropathol. Exp. Neurol, 15, 417, 10.1097/00005072-195610000-00005 Sullivan, 2009, Relevance of iron deposition in deep gray matter brain structures to cognitive and motor performance in healthy elderly men and women: Exploratory findings, Brain Imaging Behav, 3, 167, 10.1007/s11682-008-9059-7 Tobin, 1958, Estimation of relationships for limited dependent variables, Econometrica, 26, 24, 10.2307/1907382 Valdés Hernández, 2010, New multispectral MRI data fusion technique for white matter lesion segmentation: method and comparison with thresholding in FLAIR images, Eur. Radiol, 10.1007/s00330-010-1718-6 Waldstein, 2001 Wechsler, 1998 Yao, 2009, Susceptibility contrast in high field MRI of human brain as a function of tissue iron content, Neuroimage, 44, 1259, 10.1016/j.neuroimage.2008.10.029 Deary, 2007, The Lothian Birth Cohort 1936: a study to examine influences on cognitive ageing from age eleven to age seventy and beyond, BMC Geriatr, 7, 28, 10.1186/1471-2318-7-28 1949 Wechsler, 1998