Apolipoprotein E genotype and cardiovascular disease in the Framingham Heart Study

Atherosclerosis - Tập 154 - Trang 529-537 - 2001
Carlos Lahoz1, Ernst J. Schaefer1, L.Adrienne Cupples2, Peter W.F. Wilson3, Daniel Levy3, Doreen Osgood1, Stefanos Parpos1, Juan Pedro-Botet1, Jennifer A. Daly1, Jose M. Ordovas1
1Lipid Metabolism Laboratory, Jean Mayer-USDA Human Nutrition Research Center on Aging at Tufts University, 711 Washington St., Boston, MA 02111, USA
2Boston University, School of Public Health, Boston, MA, 02118, USA
3Boston University School of Medicine, Boston MA 02118 and The Framingham Heart Study, Framingham, MA 01702, USA

Tài liệu tham khảo

Exp Panel High Blood Chol Adults. Summary of the second report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel II). JAMA 1993;269:3015–3023. Genest, 1992, Familial lipoprotein disorders in patients with premature coronary artery disease, Circulation, 85, 2025, 10.1161/01.CIR.85.6.2025 Boerwinkle, 1992, Apolipoprotein(a) gene accounts for greater than 90% of the variation in plasma lipoprotein(a) concentrations, J. Clin. Invest., 90, 52, 10.1172/JCI115855 Brown, 1986, A receptor-mediated pathway for cholesterol homeostasis, Science, 232, 34, 10.1126/science.3513311 Russell, 1989, Molecular basis of familiar hypercholestolemia, Arteriosclerosis, 9, I8 Goldstein, 1973, Hyperlipidemia in coronary heart disease. II. Genetic analysis of lipid levels in 176 families and delineation of a new inherited disorder, combined hyperlipidemia, J. Clin. Invest., 52, 1544, 10.1172/JCI107332 Davignon, 1988, Apolipoprotein E polymorphism and atherosclerosis, Arteriosclerosis, 8, 1, 10.1161/01.ATV.8.1.1 Ordovas, 1987, Apolipoprotein E isoform phenotyping methodology and population frequency with identification of apoE1 and apoE5 isoforms, J. Lipid Res., 28, 371, 10.1016/S0022-2275(20)38690-9 Ehnholm, 1986, Apolipoprotein E polymorphism in the Finnish population: gene frequencies and relation to lipoprotein concentrations, J. Lipid Res., 27, 227, 10.1016/S0022-2275(20)38833-7 Xhignesse, 1991, Influences of common variants of apolipoprotein E on measures of lipid metabolism in a sample selected for health, Arterioscler. Thromb., 11, 1100, 10.1161/01.ATV.11.4.1100 Kamboh, 1993, Impact of apolipoprotein E polymorphism in determining interindividual variation in total cholesterol and low density lipoprotein cholesterol in Hispanics and non-Hispanic whites, Atherosclerosis, 98, 201, 10.1016/0021-9150(93)90129-I Schaefer, 1994, Effects of gender and menopausal status on the association of apolipoprotein E phenotype with plasma lipoprotein levels: Results from the Framingham Offspring Study, Arterioscler. Thromb., 14, 1105, 10.1161/01.ATV.14.7.1105 Rall, 1982, Human apolipoprotein E: the complete amino acid sequence, J. Biol. Chem., 257, 4171, 10.1016/S0021-9258(18)34702-1 Dallongeville, 1992, Modulation of plasma triglyceride levels by apoE phenotype: A meta-analysis, J. Lipid Res., 33, 447, 10.1016/S0022-2275(20)41611-6 Wilson, 1996, Apolipoprotein E alleles and risk of coronary disease — A meta-analysis, Arterioscler. Thromb. Vasc. Biol., 16, 1250, 10.1161/01.ATV.16.10.1250 Dawber, 1951, Epidemiological approaches to heart disease: The Framingham Study, Am. J. Public Health, 41, 279, 10.2105/AJPH.41.3.279 Kannel, 1979, An investigation of coronary heart disease in families: the Framingham Offspring Study, Am. J. Epidemiol., 110, 281, 10.1093/oxfordjournals.aje.a112813 Miller, 1989, A simple salting out procedure for extracting DNA from human nucleated cells, Nucleic Acids Res., 16, 1215, 10.1093/nar/16.3.1215 Hixson, 1990, Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with HhaI, J. Lipid Res., 31, 545, 10.1016/S0022-2275(20)43176-1 Lipid Research Clinics Program. The Coronary Primary Prevention Trial: design and implementation. J Chron Dis 1979;14:1250–1257. Anonymous. The coronary primary prevention trial: design and implementation: the Lipid Research Clinics Program. J Chron Dis 1979;32:609–631. Gagne, 1994, Analysis of DNA changes in the LPL gene in patients with familial combined hyperlipidemia, Arterioscler. Thromb., 14, 1250, 10.1161/01.ATV.14.8.1250 Cumming, 1984, Polymorphism at the apoprotein-E locus in relation to risk of coronary disease, Clin. Genet., 25, 310, 10.1111/j.1399-0004.1984.tb01995.x Lenzen, 1986, Association of Apolipoprotein E polymorphism, low-density lipoprotein cholesterol, and coronary artery disease, Clin. Chem., 32, 778, 10.1093/clinchem/32.5.778 Eto, 1989, Increased frequencies of apolipoprotein E2 and E4 alleles in patients with ischemic heart disease, Clin. Genet., 36, 183, 10.1111/j.1399-0004.1989.tb03186.x Yamamura, 1990, Hyperlipoproteinemia as a risk factor for ischemic heart disease, Jpn. Circ. J., 54, 448, 10.1253/jcj.54.448 Eichner, 1993, Relation of apolipoprotein E phenotype to myocardial infarction and mortality from coronary artery disease, Am. J. Cardiol., 71, 160, 10.1016/0002-9149(93)90732-R Luc, 1994, Impact of apolipoprotein E polymorphism on lipoproteins and risk of myocardial infarction: The ECTIM study, Arterioscler. Thromb., 14, 1412, 10.1161/01.ATV.14.9.1412 Wilson, 1994, Apolipoprotein E alleles, dyslipidemia, and coronary heart disease: The Framingham Offspring Study, JAMA, 272, 1666, 10.1001/jama.272.21.1666 Stengård, 1995, Apolipoprotein E polymorphism predicts death from coronary heart disease in a longitudinal study of elderly Finnish men, Circulation, 91, 265, 10.1161/01.CIR.91.2.265 Utermann, 1984, Apolipoprotein E phenotypes in patients with myocardial infarction, Hum. Genet., 65, 237, 10.1007/BF00286509 Scaglione, 1999, Role of lipid, apolipoprotein levels and apolipoprotein E genotype in young Italian patients with myocardial infarction, Nutr. Metab. Cardiovasc. Dis., 9, 118 Corbo, 1999, Apolipoprotein E genotype and plasma levels in coronary artery disease. A case-control study in the Italian population, Clin. Biochem., 32, 217, 10.1016/S0009-9120(99)00011-9 Nakai, 1998, Polymorphism of the apolipoprotein E and angiotensin I converting enzyme genes in Japanese patients with myocardial infarction, Coronary Artery Dis., 9, 329, 10.1097/00019501-199809060-00002 Ou, 1998, Methylenetetrahydrofolate reductase and apolipoprotein E polymorphisms are independent risk factors for coronary heart disease in Japanese: a case-control study, Atherosclerosis, 137, 23, 10.1016/S0021-9150(97)00244-X Nassar, 1999, Relation of genetic polymorphisms of apolipoprotein E, angiotensin converting enzyme, apolipoprotein B-100, and glycoprotein IIIa and early-onset coronary heart disease, Clin. Biochem., 32, 275, 10.1016/S0009-9120(99)00017-X Biggart, 1998, Association of genetic polymorphisms in the ACE, ApoE, and TGF beta genes with early onset ischemic heart disease, Clin. Cardiol., 21, 831, 10.1002/clc.4960211109 Moore, 1999, The role of the apolipoprotein E polymorphism in the prediction of coronary artery disease age of onset, Clin. Genet., 51, 22, 10.1111/j.1399-0004.1997.tb02408.x Raslova, 1999, Apolipoprotein E genotypes in offspring with a positive and negative family history of premature myocardial infarction, Clin. Genet., 53, 387, 10.1111/j.1399-0004.1998.tb02751.x Tiret, 1994, ApoE polymorphism and predisposition to coronary heart disease in youths of different European populations: The EARS Study, Arterioscler. Thromb., 14, 1617, 10.1161/01.ATV.14.10.1617 Menzel, 1983, Apolipoprotein E polymorphism and coronary artery disease, Arteriosclerosis, 3, 310, 10.1161/01.ATV.3.4.310 Kuusi, 1989, Apolipoprotein E polymorphism and coronary artery disease. Increased prevalence of apolipoprotein E-4 in angiographically verified coronary patients, Arteriosclerosis, 9, 237, 10.1161/01.ATV.9.2.237 Stuyt, 1991, Apolipoprotein E phenotypes, serum lipoproteins and apolipoproteins in angiographically assessed coronary heart disease, Scand. J. Clin. Lab. Invest., 51, 425, 10.3109/00365519109091636 Van Bockxmeer, 1992, Apolipoprotein ε4 homozygosity in young men with coronary heart disease, Lancet, 340, 879, 10.1016/0140-6736(92)93288-X Lehtinen, 1995, Apolipoprotein E polymorphism, serum lipids, myocardial infarction and severity of angiographically verified coronary artery disease in men and women, Atherosclerosis, 114, 83, 10.1016/0021-9150(94)05469-Y Wang, 1995, Polymorphisms of the apolipoprotein E gene and severity of coronary artery disease defined by angiography, Arterioscler. Thromb. Vasc. Biol., 15, 1030, 10.1161/01.ATV.15.8.1030 De Andrade, 1995, Relationship of the apolipoprotein E polymorphism with carotid artery atherosclerosis, Am. J. Hum. Genet., 56, 1379 Kardia, 1999, The relationship between risk factor levels and presence of coronary artery calcification is dependent on apolipoprotein E genotype, Arterioscler. Thromb. Vasc. Biol., 19, 427, 10.1161/01.ATV.19.2.427 Cattin, 1997, Polymorphism of the apolipoprotein E gene and early carotid atherosclerosis defined by ultrasonography in asymptomatic adults, Arterioscler. Thromb. Vasc. Biol., 17, 91, 10.1161/01.ATV.17.1.91 Hixson JE, PDAY Research Group. Apolipoprotein E polymorphisms affect atherosclerosis in young males. Arterioscler Thromb 1991;11:1237–1244. Scheer, 1995, Apolipoprotein E and atherosclerosis in Alaska Natives, Atherosclerosis, 114, 197, 10.1016/0021-9150(94)05483-Y Ilveskoski, 1999, Age-dependent association of apolipoprotein E genotype with coronary and aortic atherosclerosis in middle-aged men — An autopsy study, Circulation, 100, 608, 10.1161/01.CIR.100.6.608 Boer, 1998, Lipid profiles reflecting high and low risk for coronary heart disease: contribution of apolipoprotein E polymorphism and lifestyle, Atherosclerosis, 136, 395, 10.1016/S0021-9150(97)00231-1 Boerwinkle, 1994, Apolipoprotein E polymorphism influences postprandial retinyl palmitate but not triglyceride concentrations, Am. J. Hum. Genet., 54, 341 Dallongeville, 1999, Effect of apo E phenotype on plasma postprandial triglyceride levels in young male adults with and without a familial history of myocardial infarction: the EARS II study. European Atherosclerosis Research Study, Atherosclerosis, 145, 381, 10.1016/S0021-9150(99)00069-6 Orchard, 1994, Insulin as a predictor of coronary heart disease: interaction with apolipoprotein E phenotype, A report from the Multiple Risk Factor Intervention Trial, Ann. Epidemiol., 4, 40, 10.1016/1047-2797(94)90041-8 Karpe, 1997, Mechanisms of postprandial hyperlipidemia — remnants and coronary artery disease, Diabetic Med., 14, S60, 10.1002/(SICI)1096-9136(199708)14:3+<S60::AID-DIA447>3.3.CO;2-M Brussaard, 1997, Short-term oestrogen replacement therapy improves insulin resistance, lipids and fibrinolysis in postmenopausal women with NIDDM, Diabetologia, 40, 843, 10.1007/s001250050758 Wilcox, 1997, Cardioprotective effects of individual conjugated equine estrogens through their possible modulation of insulin resistance and oxidation of low-density lipoprotein, Fertil. Steril., 67, 57, 10.1016/S0015-0282(97)81856-0 Huang, 1997, Apolipoprotein E2 transgenic rabbits, J. Biol. Chem., 272, 22685, 10.1074/jbc.272.36.22685 Srivastava, 1997, Estrogen up-regulates apolipoprotein E (ApoE) gene expression by increasing ApoE mRNA in the translating pool via the estrogen receptor alpha-mediated pathway, J. Biol. Chem., 272, 33360, 10.1074/jbc.272.52.33360 Ordovas, 1999, Genes, variation of cholesterol and fat intake and serum lipids, Curr. Opin. Lipidol., 10, 15, 10.1097/00041433-199902000-00004 Ordovas, 1999, The genetics of serum lipid responsiveness to dietary interventions, Proc. Nutr. Soc., 58, 171, 10.1079/PNS19990023 Rantala, 1997, Apolipoprotein E phenotype and diet-induced alteration in blood pressure, Am. J. Clin. Nutr., 65, 543, 10.1093/ajcn/65.2.543 Aguilar, 1999, The apolipoprotein E4 allele is not associated with an abnormal lipid profile in a Native American population following its traditional lifestyle, Atherosclerosis, 142, 409, 10.1016/S0021-9150(98)00251-2 Kamboh, 1991, Genetic studies of human apolipoproteins. XVI. APOE polymorphism and cholesterol levels in the Mayans of the Yucatan Peninsula, Mexico, Clin. Genet., 39, 26, 10.1111/j.1399-0004.1991.tb02981.x Deiana, 1998, Lack of influence of apolipoprotein E4 on lipoprotein levels in the island population of Sardinia, Eur. J. Clin. Invest., 28, 290, 10.1046/j.1365-2362.1998.00271.x Sandholzer, 1995, High frequency of the apo epsilon 4 allele in Khoi San from South Africa, Hum. Genet., 95, 46, 10.1007/BF00225073