Photodynamic assistance increases the efficiency of the process of microinjection in animal cells

Biotechnology Letters - Tập 24 - Trang 309-314 - 2002
Takashi K. Saito1, Hitoshi Muguruma2, Kunihiko Mabuchi1
1Center for Collaborative Research, University of Tokyo, Meguro-ku, Tokyo, Japan
2Department of Electronic Engineering, Shibaura Institute of Technology, Minato-ku, Tokyo, Japan

Tóm tắt

A microinjection process is described that involves the photodynamically-assisted puncture of an animal cell membrane by means of a brief and partial degeneration resulting from cell membrane damage. The ratio of dye-injected rat pheochromocytoma cells that became detached three and six days after photodynamically-assisted microinjection was 9%; however, it was 83% when a conventional mechanical microinjection process was used.

Tài liệu tham khảo

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