Cathepsin G: Roles in antigen presentation and beyond
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Adkison, 2002, Dipeptidyl peptidase I activates neutrophil-derived serine proteases and regulates the development of acute experimental arthritis, J. Clin. Invest., 109, 363, 10.1172/JCI0213462
Allen, 1995, Human coagulation factor V is activated to the functional cofactor by elastase and cathepsin G expressed at the monocyte surface, J. Biol. Chem., 270, 1408, 10.1074/jbc.270.3.1408
Anderssen, 1993, Human leukocyte elastase and cathepsin G inactivate factor VII by limited proteolysis, Thromb. Haemost., 70, 414, 10.1055/s-0038-1649596
Baggiolini, 1978, The polymorphonuclear leukocyte, Agents Actions, 8, 3, 10.1007/BF01972395
Baggiolini, 1979, Cellular mechanisms of proteinase release from inflammatory cells and the degradation of extracellular proteins, Ciba Found. Symp., 105
Baici, 1982, Cathepsin G from human polymorphonuclear leukocytes cleaves human IgM, Mol. Immunol., 19, 719, 10.1016/0161-5890(82)90373-X
Baici, 1982, Cleavage of the four human IgG subclasses with cathepsin G, Scand. J. Immunol., 16, 487, 10.1111/j.1365-3083.1982.tb00750.x
Banchereau, 1998, Dendritic cells and the control of immunity, Nature, 392, 245, 10.1038/32588
Bank, 2001, More than destructive: neutrophil-derived serine proteases in cytokine bioactivity control, J. Leukoc. Biol., 69, 197, 10.1189/jlb.69.2.197
Beck, 2001, Cathepsin S and an asparagine-specific endoprotease dominate the proteolytic processing of human myelin basic protein in vitro, Eur. J. Immunol., 31, 3726, 10.1002/1521-4141(200112)31:12<3726::AID-IMMU3726>3.0.CO;2-O
Bennett, 1992, Antigen processing for presentation by class II major histocompatibility complex requires cleavage by cathepsin E, Eur. J. Immunol., 22, 1519, 10.1002/eji.1830220626
Boehm, 2009, Protease-resistant human GAD-derived altered peptide ligands decrease TNF-alpha and IL-17 production in peripheral blood cells from patients with type 1 diabetes mellitus, Mol. Immunol., 46, 2576, 10.1016/j.molimm.2009.05.007
Boudier, 1991, The elastolytic activity of cathepsin G: an ex vivo study with dermal elastin, Am. J. Respir. Cell Mol. Biol., 4, 497, 10.1165/ajrcmb/4.6.497
Bromme, 1999, Human cathepsin V functional expression, tissue distribution, electrostatic surface potential, enzymatic characterization, and chromosomal localization, Biochemistry, 38, 2377, 10.1021/bi982175f
Burster, 2007, Interferon-gamma regulates cathepsin G activity in microglia-derived lysosomes and controls the proteolytic processing of myelin basic protein in vitro, Immunology, 121, 82, 10.1111/j.1365-2567.2007.02540.x
Burster, 2004, Cathepsin G, and not the asparagine-specific endoprotease, controls the processing of myelin basic protein in lysosomes from human B lymphocytes, J. Immunol., 172, 5495, 10.4049/jimmunol.172.9.5495
Burster, 2005, Differential processing of autoantigens in lysosomes from human monocyte-derived and peripheral blood dendritic cells, J. Immunol., 175, 5940, 10.4049/jimmunol.175.9.5940
Burster, 2008, Cathepsin E regulates the presentation of tetanus toxin C-fragment in PMA activated primary human B cells, Biochem. Biophys. Res. Commun., 377, 1299, 10.1016/j.bbrc.2008.10.162
Busch, 2005, Achieving stability through editing and chaperoning: regulation of MHC class II peptide binding and expression, Immunol. Rev., 207, 242, 10.1111/j.0105-2896.2005.00306.x
Castori, 2009, Novel CTSC mutations in a patient with Papillon–Lefevre syndrome with recurrent pyoderma and minimal oral and palmoplantar involvement, Br. J. Dermatol., 160, 881, 10.1111/j.1365-2133.2008.08878.x
Chain, 2005, The expression and function of cathepsin E in dendritic cells, J. Immunol., 174, 1791, 10.4049/jimmunol.174.4.1791
Chapman, 2006, Endosomal proteases in antigen presentation, Curr. Opin. Immunol., 18, 78, 10.1016/j.coi.2005.11.011
Chapman, 1997, Emerging roles for cysteine proteases in human biology, Annu. Rev. Physiol., 59, 63, 10.1146/annurev.physiol.59.1.63
Colbert, 2009, Diverse regulatory roles for lysosomal proteases in the immune response, Eur. J. Immunol., 10.1002/eji.200939650
Cole, 2001, Inhibition of neutrophil elastase prevents cathelicidin activation and impairs clearance of bacteria from wounds, Blood, 97, 297, 10.1182/blood.V97.1.297
Coyle, 1994, Role of cationic proteins in the airway. Hyperresponsiveness due to airway inflammation, Am. J. Respir. Crit. Care Med., 150, S63, 10.1164/ajrccm/150.5_Pt_2.S63
Delamarre, 2005, Differential lysosomal proteolysis in antigen-presenting cells determines antigen fate, Science, 307, 1630, 10.1126/science.1108003
Delgado, 2001, Rapid inactivation of stromal cell-derived factor-1 by cathepsin G associated with lymphocytes, Eur. J. Immunol., 31, 699, 10.1002/1521-4141(200103)31:3<699::AID-IMMU699>3.0.CO;2-6
Dewald, 1975, Subcellular localization and heterogeneity of neutral proteases in neutrophilic polymorphonuclear leukocytes, J. Exp. Med., 141, 709, 10.1084/jem.141.4.709
Doring, 1995, Cleavage of lymphocyte surface antigens CD2, CD4, and CD8 by polymorphonuclear leukocyte elastase and cathepsin G in patients with cystic fibrosis, J. Immunol., 154, 4842, 10.4049/jimmunol.154.9.4842
Dudziak, 2007, Differential antigen processing by dendritic cell subsets in vivo, Science, 315, 107, 10.1126/science.1136080
Eliassen, 2000, TNF 41-62 and TNF 78-96 have distinct effects on LPS-induced tissue factor activity and the production of cytokines in human blood cells, Thromb. Haemost., 83, 598, 10.1055/s-0037-1613870
Gale, 2008, Cathepsin G, a leukocyte protease, activates coagulation factor VIII, Thromb. Haemost., 99, 44, 10.1160/TH07-08-0495
Garwicz, 2005, Biosynthetic profiles of neutrophil serine proteases in a human bone marrow-derived cellular myeloid differentiation model, Haematologica, 90, 38
Gonzalez-Scarano, 1999, Microglia as mediators of inflammatory and degenerative diseases, Annu. Rev. Neurosci., 22, 219, 10.1146/annurev.neuro.22.1.219
Gorlin, 1964, The syndrome of Palmar–Plantar hyperkeratosis and premature periodontal destruction of the teeth. A clinical and genetic analysis of the Papillon–Lefèvre syndrome, J. Pediatr., 65, 895, 10.1016/S0022-3476(64)80014-7
Grisolano, 1994, Early myeloid cell-specific expression of the human cathepsin G gene in transgenic mice, Proc. Natl. Acad. Sci. U.S.A., 91, 8989, 10.1073/pnas.91.19.8989
Hanson, 1990, Developmental regulation of the human cathepsin G gene in myelomonocytic cells, J. Biol. Chem., 265, 1524, 10.1016/S0021-9258(19)40048-3
Hart, 1999, Mutations of the cathepsin C gene are responsible for Papillon–Lefevre syndrome, J. Med. Genet., 36, 881, 10.1136/jmg.36.12.881
Hart, 1994, Papillon–Lefevre syndrome, Periodontology 2000, 6, 88, 10.1111/j.1600-0757.1994.tb00029.x
Hedin, 1904, Investigations on the proteolytic enzymes of the spleen of the ox, J. Physiol., 30, 155, 10.1113/jphysiol.1903.sp000987
Hedin, 1901, Zeit. Physiol. Chem., xxxii, 341, 10.1515/bchm2.1901.32.3-4.341
Hewitt, 1997, Natural processing sites for human cathepsin E and cathepsin D in tetanus toxin: implications for T cell epitope generation, J. Immunol., 159, 4693, 10.4049/jimmunol.159.10.4693
Hohn, 1989, Genomic organization and chromosomal localization of the human cathepsin G gene, J. Biol. Chem., 264, 13412, 10.1016/S0021-9258(18)80012-6
Hu, 2005, Dipeptidyl peptidase I regulates the development of collagen-induced arthritis, Arthritis Rheum., 52, 2553, 10.1002/art.21192
Ishri, 2004, Rapid downregulation of antigen processing enzymes in ex vivo generated human monocyte derived dendritic cells occur endogenously in extended cultures, Immunol. Cell Biol., 82, 239, 10.1046/j.1440-1711.2004.01237.x
Kamp, 1993, Asbestos-induced injury to cultured human pulmonary epithelial-like cells: role of neutrophil elastase, J. Leukoc. Biol., 54, 73, 10.1002/jlb.54.1.73
Korkmaz, 2008, Neutrophil elastase, proteinase 3 and cathepsin G: physicochemical properties, activity and physiopathological functions, Biochimie, 90, 227, 10.1016/j.biochi.2007.10.009
Kossel, 1888, Zeit. klin. Med., xiii, 149
Lautwein, 2004, Human B lymphoblastoid cells contain distinct patterns of cathepsin activity in endocytic compartments and regulate MHC class II transport in a cathepsin S-independent manner, J. Leukoc. Biol., 75, 844, 10.1189/jlb.0803367
LaRosa, 1994, Human neutrophil cathepsin G is a potent platelet activator, J. Vasc. Surg., 19, 306, 10.1016/S0741-5214(94)70106-7
Le-Barillec, 2000, Human neutrophil cathepsin G down-regulates LPS-mediated monocyte activation through CD14 proteolysis, J. Leukoc. Biol., 68, 209, 10.1189/jlb.68.2.209
Lebez, 1970, Leucocyte proteinases. I. Low molecular weight cathepsins of F and G type, Enzymologia, 39, 271
Li, 2003, Multistep autoactivation of asparaginyl endopeptidase in vitro and in vivo, J. Biol. Chem., 278, 38980, 10.1074/jbc.M305930200
Lucey, 1985, Effect of combined human neutrophil cathepsin G and elastase on induction of secretory cell metaplasia and emphysema in hamsters, with in vitro observations on elastolysis by these enzymes, Am. Rev. Respir. Dis., 132, 362
Mambole, 2008, The cleavage of neutrophil leukosialin (CD43) by cathepsin G releases its extracellular domain and triggers its intramembrane proteolysis by presenilin/gamma-secretase, J. Biol. Chem., 283, 23627, 10.1074/jbc.M710286200
Manoury, 2002, Destructive processing by asparagine endopeptidase limits presentation of a dominant T cell epitope in MBP, Nat. Immunol., 3, 169, 10.1038/ni754
Maynard, 2005, Structure of an autoimmune T cell receptor complexed with class II peptide-MHC: insights into MHC bias and antigen specificity, Immunity, 22, 81
McGettrick, 2001, SCCA2 inhibits TNF-mediated apoptosis in transfected HeLa cells. The reactive centre loop sequence is essential for this function and TNF-induced cathepsin G is a candidate target, Eur. J. Biochem., 268, 5868, 10.1046/j.0014-2956.2001.02535.x
McGuire, 1993, Generation of active myeloid and lymphoid granule serine proteases requires processing by the granule thiol protease dipeptidyl peptidase I, J. Biol. Chem., 268, 2458, 10.1016/S0021-9258(18)53798-4
Medema, 2001, Expression of the serpin serine protease inhibitor 6 protects dendritic cells from cytotoxic T lymphocyte-induced apoptosis: differential modulation by T helper type 1 and type 2 cells, J. Exp. Med., 194, 657, 10.1084/jem.194.5.657
Meier, 1985, Purified human mast cells and basophils release human elastase and cathepsin G by an IgE-mediated mechanism, Int. Arch. Allergy Appl. Immunol., 77, 179, 10.1159/000233779
Metchnikoff, 1884, Über die pathologische Bedeutung der intrazellulären, Verdauung Fortschr Med., 17, 558
Metchnikoff E, 1901
Meyer-Hoffert, 2009, Neutrophil-derived serine proteases modulate innate immune responses, Front. Biosci., 14, 3409, 10.2741/3462
Miyata, 2007, Cathepsin G: the significance in rheumatoid arthritis as a monocyte chemoattractant, Rheumatol. Int., 27, 375, 10.1007/s00296-006-0210-8
Molino, 1992, Intracellular Ca2+ rise in human platelets induced by polymorphonuclear-leucocyte-derived cathepsin G, Biochem. J., 288, 741, 10.1042/bj2880741
Moss, 2005, Destructive potential of the aspartyl protease cathepsin D in MHC class II-restricted antigen processing, Eur. J. Immunol., 35, 3442, 10.1002/eji.200535320
Mounter, 1960, Proteases of human leukocytes, Blood, 15, 52, 10.1182/blood.V15.1.52.52
Nathan, 2006, Neutrophils and immunity: challenges and opportunities, Nat. Rev. Immunol., 6, 173, 10.1038/nri1785
Nufer, 1999, Amino-terminal processing of chemokine ENA-78 regulates biological activity, Biochemistry, 38, 636, 10.1021/bi981294s
Nygaard, 1993, Defensins reduce the barrier integrity of a cultured epithelial monolayer without cytotoxicity, Am. J. Respir. Cell Mol. Biol., 8, 193, 10.1165/ajrcmb/8.2.193
Ochiai, 2009, Novel p.M1T and recurrent p.G301S mutations in cathepsin C in a Japanese patient with Papillon–Lefevre syndrome: implications for understanding the genotype/phenotype relationship, J. Dermatol. Sci., 53, 73, 10.1016/j.jdermsci.2008.07.006
Odeberg, 1975, Antibacterial activity of cationic proteins from human granulocytes, J. Clin. Invest., 56, 1118, 10.1172/JCI108186
Ohlsson, 1977, Localization of chymotrypsin-like cationic protein, collagenase and elastase in azurophil granules of human neutrophilic polymorphonuclear leukocytes, Hoppe-Seylers Z. Physiol. Chem., 358, 361, 10.1515/bchm2.1977.358.1.361
Okrent, 1990, Direct cytotoxicity of polymorphonuclear leukocyte granule proteins to human lung-derived cells and endothelial cells, Am. Rev. Respir. Dis., 141, 179, 10.1164/ajrccm/141.1.179
Oleksyszyn, 1991, Irreversible inhibition of serine proteases by peptide derivatives of (alpha-aminoalkyl)phosphonate diphenyl esters, Biochemistry, 30, 485, 10.1021/bi00216a026
Owen, 1998, Angiotensin II generation at the cell surface of activated neutrophils: novel cathepsin G-mediated catalytic activity that is resistant to inhibition, J. Immunol., 160, 1436, 10.4049/jimmunol.160.3.1436
Owen, 1999, Extracellular proteolysis: new paradigms for an old paradox, J. Lab. Clin. Med., 134, 341, 10.1016/S0022-2143(99)90148-8
Owen, 1999, The cell biology of leukocyte-mediated proteolysis, J. Leukoc. Biol., 65, 137, 10.1002/jlb.65.2.137
Owen, 1995, Inducible binding of bioactive cathepsin G to the cell surface of neutrophils. A novel mechanism for mediating extracellular catalytic activity of cathepsin G, J. Immunol., 155, 5803, 10.4049/jimmunol.155.12.5803
Owen, 1995, Cell surface-bound elastase and cathepsin G on human neutrophils: a novel, non-oxidative mechanism by which neutrophils focus and preserve catalytic activity of serine proteinases, J. Cell Biol., 131, 775, 10.1083/jcb.131.3.775
Peterson, 1995, Effect of neutrophil mediators on epithelial permeability, Am. J. Respir. Cell Mol. Biol., 13, 719, 10.1165/ajrcmb.13.6.7576710
Pham, 2006, Neutrophil serine proteases: specific regulators of inflammation, Nat. Rev. Immunol., 6, 541, 10.1038/nri1841
Pham, 2008, Neutrophil serine proteases fine-tune the inflammatory response, Int. J. Biochem. Cell Biol., 40, 1317, 10.1016/j.biocel.2007.11.008
Pham, 2004, Papillon–Lefèvre syndrome: correlating the molecular, cellular, and clinical consequences of cathepsin C/dipeptidyl peptidase I deficiency in humans, J. Immunol., 173, 7277, 10.4049/jimmunol.173.12.7277
Rao, 1997, Human dipeptidyl-peptidase I. Gene characterization, localization, and expression, J. Biol. Chem, 272, 10260, 10.1074/jbc.272.15.10260
Raptis, 2005, Serine protease cathepsin G regulates adhesion-dependent neutrophil effector functions by modulating integrin clustering, Immunity, 22, 679, 10.1016/j.immuni.2005.03.015
Reeves, 2002, Killing activity of neutrophils is mediated through activation of proteases by K+ flux, Nature, 416, 291, 10.1038/416291a
Rehault, 1999, New, sensitive fluorogenic substrates for human cathepsin G based on the sequence of serpin-reactive site loops, J. Biol. Chem., 274, 13810, 10.1074/jbc.274.20.13810
Reich, 2009, Application of specific cell permeable cathepsin G inhibitors resulted in reduced antigen processing in primary dendritic cells, Mol. Immunol., 46, 2994, 10.1016/j.molimm.2009.06.017
Remold-O’Donnell, 1992, Sequence and molecular characterization of human monocyte/neutrophil elastase inhibitor, Proc. Natl. Acad. Sci. U.S.A., 89, 5635, 10.1073/pnas.89.12.5635
Richter, 2005, Quantum proteolytic activation of chemokine CCL15 by neutrophil granulocytes modulates mononuclear cell adhesiveness, J. Immunol., 175, 1599, 10.4049/jimmunol.175.3.1599
Riese, 1996, Essential role for cathepsin S in MHC class II-associated invariant chain processing and peptide loading, Immunity, 4, 357, 10.1016/S1074-7613(00)80249-6
Rindler-Ludwig, 1975, Cationic proteins from human neutrophil granulocytes. Evidence for their chymotrypsin-like properties, Biochim. Biophys. Acta, 379, 606, 10.1016/0005-2795(75)90167-1
Rudensky, 2006, Lysosomal cysteine proteases and antigen presentation, 81
Sabri, 2003, Neutrophil cathepsin G promotes detachment-induced cardiomyocyte apoptosis via a protease-activated receptor-independent mechanism, J. Biol. Chem., 278, 23944, 10.1074/jbc.M302718200
Salkowski, 1890, Zeit. klin. Med., xvii, 77
Salvesen, 1987, Molecular cloning of human cathepsin G: structural similarity to mast cell and cytotoxic T lymphocyte proteinases, Biochemistry, 26, 2289, 10.1021/bi00382a032
Sambrano, 2000, Cathepsin G activates protease-activated receptor-4 in human platelets, J. Biol. Chem., 275, 6819, 10.1074/jbc.275.10.6819
Scuderi, 1991, Cathepsin-G and leukocyte elastase inactivate human tumor necrosis factor and lymphotoxin, Cell. Immunol., 135, 299, 10.1016/0008-8749(91)90275-G
Selak, 1990, Cathepsin G binding to human platelets. Evidence for a specific receptor, Biochem. J., 266, 55, 10.1042/bj2660055
Senior, 1984, Cathepsin G in human mononuclear phagocytes: comparisons between monocytes and U937 monocyte-like cells, J. Immunol., 132, 2547, 10.4049/jimmunol.132.5.2547
Shafer, 1996, Bactericidal activity of a synthetic peptide (CG 117–136) of human lysosomal cathepsin G is dependent on arginine content, Infect. Immun., 64, 4842, 10.1128/IAI.64.11.4842-4845.1996
Shafer, 1989, Mechanism of staphylococcal resistance to non-oxidative antimicrobial action of neutrophils: importance of pH and ionic strength in determining the bactericidal action of cathepsin G, J. Gen. Microbiol., 135, 825
Shafer, 1986, Antigonococcal activity of human neutrophil cathepsin G, Infect. Immun., 54, 184, 10.1128/IAI.54.1.184-188.1986
Shapiro, 1991, Proteinases secreted by human mononuclear phagocytes, J. Rheumatol. Suppl., 27, 95
Shi, 2000, Role for cathepsin F in invariant chain processing and major histocompatibility complex class II peptide loading by macrophages, J. Exp. Med., 191, 1177, 10.1084/jem.191.7.1177
Shortman, 2007, Steady-state and inflammatory dendritic-cell development, Nat. Rev. Immunol., 7, 19, 10.1038/nri1996
Starkey, 1976, Human cathepsin G. Catalytic and immunological properties, Biochem. J., 155, 273, 10.1042/bj1550273
Stoeckle, 2009, Cathepsin G is differentially expressed in primary human antigen-presenting cells, Cell. Immunol., 255, 41, 10.1016/j.cellimm.2008.10.001
Stoeckle, 2009, Antigen processing and presentation in multiple sclerosis, Results Probl. Cell Differ., 10.1007/400_2009_22
Tkalcevic, 2000, Impaired immunity and enhanced resistance to endotoxin in the absence of neutrophil elastase and cathepsin G, Immunity, 12, 201, 10.1016/S1074-7613(00)80173-9
Toomes, 1999, Loss-of-function mutations in the cathepsin C gene result in periodontal disease and palmoplantar keratosis, Nat. Genet., 23, 421, 10.1038/70525
Turk, 2000, Lysosomal cysteine proteases: more than scavengers, Biochim. Biophys. Acta, 1477, 98, 10.1016/S0167-4838(99)00263-0
Turkington, 1991, Degradation of human factor X by human polymorphonuclear leucocyte cathepsin G and elastase, Haemostasis, 21, 111
Van Wetering, 1997, Effect of neutrophil serine proteinases and defensins on lung epithelial cells: modulation of cytotoxicity and IL-8 production, J. Leukoc. Biol., 62, 217, 10.1002/jlb.62.2.217
Villadangos, 2000, Proteolysis in MHC class II antigen presentation: who's in charge?, Immunity, 12, 233, 10.1016/S1074-7613(00)80176-4
Villadangos, 1997, Degradation of mouse invariant chain: roles of cathepsins S and D and the influence of major histocompatibility complex polymorphism, J. Exp. Med., 186, 549, 10.1084/jem.186.4.549
Villadangos, 2007, Intrinsic and cooperative antigen-presenting functions of dendritic-cell subsets in vivo, Nat. Rev. Immunol., 7, 543, 10.1038/nri2103
Villadangos, 2005, Control of MHC class II antigen presentation in dendritic cells: a balance between creative and destructive forces, Immunol. Rev., 207, 191, 10.1111/j.0105-2896.2005.00317.x
Watorek, 1993, The isoforms of human neutrophil elastase and cathepsin G differ in their carbohydrate side chain structures, Biol. Chem. Hoppe Seyler, 374, 385, 10.1515/bchm3.1993.374.1-6.385
Watts, 2004, The exogenous pathway for antigen presentation on major histocompatibility complex class II and CD1 molecules, Nat. Immunol., 5, 685, 10.1038/ni1088
Watts, 2005, Asparaginyl endopeptidase: case history of a class II MHC compartment protease, Immunol. Rev., 207, 218, 10.1111/j.0105-2896.2005.00312.x
Watts, 2003, Creation versus destruction of T cell epitopes in the class II MHC pathway, Ann. N.Y. Acad. Sci., 987, 9, 10.1111/j.1749-6632.2003.tb06028.x
Willstätter, 1929, Über die Proteasen der Magenschleimhaut. Erste Abhandlung über die Enzyme der Leukocyten, Hoppe-Seylers Z. Physiol. Chem., 180, 127, 10.1515/bchm2.1929.180.1-3.127
Wilson, 2008, Cathepsin G enhances mammary tumor-induced osteolysis by generating soluble receptor activator of nuclear factor-kappaB ligand, Cancer Res., 68, 5803, 10.1158/0008-5472.CAN-07-5889
Wilson, 2009, Cathepsin G-mediated activation of pro-matrix metalloproteinase 9 at the tumor-bone interface promotes transforming growth factor-beta signaling and bone destruction, Mol. Cancer Res., 7, 1224, 10.1158/1541-7786.MCR-09-0028
Wittamer, 2005, Neutrophil-mediated maturation of chemerin: a link between innate and adaptive immunity, J. Immunol., 175, 487, 10.4049/jimmunol.175.1.487
Wysocka, 2007, New chromogenic substrates of human neutrophil cathepsin G containing non-natural aromatic amino acid residues in position P1 selected by combinatorial chemistry methods, Mol. Divers., 11, 93, 10.1007/s11030-007-9063-7
Yamazaki, 1997, Cathepsin G binds to human lymphocytes, J. Leukoc. Biol., 61, 73, 10.1002/jlb.61.1.73
Yang, 2007, Novel mutations of cathepsin C gene in two Chinese patients with Papillon–Lefevre syndrome, J. Dent. Res., 86, 735, 10.1177/154405910708600809
Zaidi, 2007, A novel cell penetrating aspartic protease inhibitor blocks processing and presentation of tetanus toxoid more efficiently than pepstatin A, Biochem. Biophys. Res. Commun., 364, 243, 10.1016/j.bbrc.2007.09.114
Zaidi, 2008, Cathepsin E: a mini review, Biochem. Biophys. Res. Commun., 367, 517, 10.1016/j.bbrc.2007.12.163
Zavasnik-Bergant, 2006, Cysteine cathepsins in the immune response, Tissue Antigens, 67, 349, 10.1111/j.1399-0039.2006.00585.x