Ecological and toxicological effects of inorganic nitrogen pollution in aquatic ecosystems: A global assessment

Adams, 1994, Organic pollution: biochemical oxygen demand and ammonia, vol. 2, 264 Adams, 2000, Environmental conditions associated with domoic acid in razor clams on the Washington coast, J Shellfish Res, 19, 1007 Alabaster, 1982 Allan, 1995 Alonso A. Valoración de la degradación ambiental y efectos ecotoxicológicos sobre la comunidad de macroinvertebrados bentónicos en la cabecera del río Henares. Doctoral Dissertation, Universidad de Alcalá, Alcalá de Henares (Madrid), Spain, 2005. Alonso, 2003, Short-term toxicity of ammonia, nitrite, and nitrate to the aquatic snail Potamopyrgus antipodarum (Hydrobiidae, Mollusca), Bull Environ Contam Toxicol, 70, 1006, 10.1007/s00128-003-0082-5 Alonso, 2004, Toxic effects of unionized ammonia on survival and feeding activity of the freshwater amphipod Eulimnogammarus toletanus (Gammaridae, Crustacea), Bull Environ Contam Toxicol, 72, 1052, 10.1007/s00128-004-0350-z Anderson, 1994, Red tides, Sci Am, 271, 52, 10.1038/scientificamerican0894-62 1985 Anderson, 2002, Harmful algal blooms and eutrophication: nutrient sources, composition, and consequences, Estuaries, 25, 704, 10.1007/BF02804901 Anthonisen, 1976, Inhibition of nitrification by ammonia and nitrous acid, J Water Pollut Control Fed, 48, 835 Augspurger, 2003, Water quality guidance for protection of freshwater mussels (Unionidae) from ammonia exposure, Environ Toxicol Chem, 22, 2569, 10.1897/02-339 Austin, 1988 Ayebo, 1997, Infant methemoglobinemia in the Transylvania region in Romania, Int J Occup Environ Health, 3, 20, 10.1179/oeh.1997.3.1.20 Bache, 1986, Aluminium mobilization in soils and waters, J Geol Soc (Lond), 143, 699, 10.1144/gsjgs.143.4.0699 Baden, 1989, Brevetoxins: unique polyether dinoflagellate toxins, FASEB J, 3, 1807, 10.1096/fasebj.3.7.2565840 Baker, 1991, Acidic lakes and streams in the United States: the role of acidic deposition, Science, 252, 1151, 10.1126/science.252.5009.1151 Ball, 1967, The relative susceptibilities of some species of freshwater fish to poisons. I. Ammonia, Water Res, 1, 767, 10.1016/0043-1354(67)90019-X Biggs, 2000, Eutrophication of streams and rivers: dissolved nutrient-chlorophyll relationship for benthic algae, J North Am Benthol Soc, 19, 17, 10.2307/1468279 Birge, 2000, Comparative toxicology and risk assessment of amphibians, 727 Borchardt, 1996, Nutrients, 183 Borg, 1989, Influence of acidification on metal fluxes in Swedish forest lakes, Sci Total Environ, 87/88, 241, 10.1016/0048-9697(89)90239-8 Botes, 1982, Isolation and characterization of four toxins from the blue green alga Microcystis aeruginosa, Toxicon, 20, 945, 10.1016/0041-0101(82)90097-6 Breitburg, 2002, Effects of hypoxia, and the balance between hypoxia and enrichment, on coastal fishes and fisheries, Estuaries, 25, 767, 10.1007/BF02804904 Burkholder, 1992, New phantom dinoflagellates is the causative agent of major estuarine fish kills, Nature, 358, 407, 10.1038/358407a0 Burkholder, 1997, Pfiesteria piscicida and other Pfiesteria-like dinoflagellates: behaviour, impacts, and environmental controls, Limnol Oceanogr, 42, 1052, 10.4319/lo.1997.42.5_part_2.1052 Burkholder, 1998, Implications of harmful microalgae and heterotrophic dinoflagellates in management of sustainable marine fisheries, Ecol Appl, 8, S37, 10.1890/1051-0761(1998)8[S37:IOHMAH]2.0.CO;2 Burkholder, 2005, Demonstration of toxicity to fish and to mammalian cells by Pfiesteria species: comparison of assay methods and strains, Proc Natl Acad Sci USA, 102, 3471, 10.1073/pnas.0500168102 Busse, 2006, Domoic acid in phytoplankton and fish in San Diego, CA, USA, Harmful Algae, 5, 91, 10.1016/j.hal.2005.06.005 Calamari, 1997, Effetti di trattamenti prolungati con ammoniaca su stadi di sviluppo del Salmo gairdneri, Nuovi Ann Ig Microbiol, 28, 333 Camargo, 1992, Temporal and spatial variations in dominance, diversity and biotic indices along a limestone stream receiving a trout farm effluent, Water Air Soil Pollut, 63, 343, 10.1007/BF00475501 Camargo, 1992, Differential sensitivity of Dugesia dorotocephala and Cheumatopsyche pettiti to water acidification: ecological implication for predator–prey interactions, Arch Environ Contam Toxicol, 23, 59, 10.1007/BF00225996 Camargo, 1992, Short-term toxicity of sodium nitrate (NaNO3) to non-target freshwater invertebrates, Chemosphere, 24, 23, 10.1016/0045-6535(92)90563-7 Camargo, 1993, Ameliorating effect of sodium chloride on the tolerance of Cheumatopsyche pettiti (Trichoptera, Hydropsychidae) to water acidification, vol. II, 62 Camargo, 1995, Nitrate (NO3–N) toxicity to aquatic life: a proposal of safe concentrations for two species of Nearctic freshwater invertebrates, Chemosphere, 31, 3211, 10.1016/0045-6535(95)00182-8 Camargo, 2005, Nitrate toxicity to aquatic animals: a review with new data for freshwater invertebrates, Chemosphere, 58, 1255, 10.1016/j.chemosphere.2004.10.044 Camargo, 2005, Eutrophication downstream from small reservoirs in mountain rivers of central Spain, Water Res, 39, 3376, 10.1016/j.watres.2005.05.048 Campbell, 1990 Canadian Council of Ministers of the Environment, 2003 Carmichael, 1997, The cyanotoxins, Adv Bot Res, 7, 211, 10.1016/S0065-2296(08)60282-7 Carpenter, 1998, Nonpoint pollution of surface waters with phosphorus and nitrogen, Ecol Appl, 8, 559, 10.1890/1051-0761(1998)008[0559:NPOSWW]2.0.CO;2 Centers for Disease Control and Prevention, 1996, Spontaneous abortions possibly related to ingestion of nitrate-contaminated well water in La Grange County, Indiana, 1991–1994, Morb Mortal Wkly Rep, 45, 569 Cerhan, 2001, Association of nitrate levels in municipal drinking water and diet with risk of coronary heart disease mortality: the Iowa Women's Health Study, Epidemiology, 12, S84 457 Chamier, 1987, Effect of pH on microbial degradation of leaf litter in seven streams of the English Lake District, Oecologia, 71, 491, 10.1007/BF00379287 Chen, 1992, Accumulation of nitrite in the haemolymph of Penaeus monodon exposed to ambient nitrite, Comp Biochem Physiol, 103C, 477 Cheng, 2002, Study on the oxyhemocyanin, deoxyhemocyanin, oxygen affinity and acid–base balance of Marsupenaeus japonicus following exposure to combined elevated nitrite and nitrate, Aquatic Toxicol, 61, 181, 10.1016/S0166-445X(02)00053-X Cheng, 2002, Accumulation of nitrate in the tissues of Penaeus monodon following elevated ambient nitrate exposure after different time periods, Aquat Toxicol, 56, 133, 10.1016/S0166-445X(01)00181-3 Cirujano, 2002, Plantas acuáticas de las lagunas y humedales de Castilla-La Mancha 2001 Colwell, 2001, Marine ecosystems and cholera, Hydrobiologia, 460, 141, 10.1023/A:1013111016642 Constable, 2003, An ecological risk assessment of ammonia in the aquatic environment, Hum Ecol Risk Assess, 9, 527, 10.1080/713609921 Costa, 2004, Tissue distribution of the amnesic shellfish toxin, domoic acid, in Octopus vulgaris from the Portuguese coast, Mar Biol, 144, 971, 10.1007/s00227-003-1258-6 Craun, 1981, Methemoglobin levels in young children consuming high nitrate well water in the United States, Int J Epidemiol, 10, 309, 10.1093/ije/10.4.309 Cummins, 1994, Acid solutions, vol. 2, 21 Cusack, 2002, Confirmation of domoic acid production by Pseudo-nitzschia australis (Bacillariophyceae) isolated from Irish waters, J Phycol, 38, 1106, 10.1046/j.1529-8817.2002.01054.x Dangles, 2004, Impacts of stream acidification on litter breakdown: implications for assessing ecosystem functioning, J Appl Ecol, 41, 365, 10.1111/j.0021-8901.2004.00888.x Dawson, 1998, The toxicology of microcystins, Toxicon, 36, 953, 10.1016/S0041-0101(97)00102-5 1989 De Mott, 1997, Effects of toxic cyanobacteria and purified toxins on the survival and feeding activity of a copepod and three species of Dapnia, Limnol Oceanogr, 36, 1346, 10.4319/lo.1991.36.7.1346 Devlin, 1977, Anatoxin-a, a toxic alkaloid from Anabaena flos-aquae NCR-44h, Can J Chem, 55, 1367, 10.1139/v77-189 Diaz, 1995, Marine benthic hypoxia: a review of its ecological effects and the behavioural responses of benthic macrofauna, Oceanogr Mar Biol Ann Rev, 33, 245 Dittman, 1996, Conserved sequences of peptide synthetase genes in the cyanobacterium Microcystis aeruginosa, Phycologia, 35, 62, 10.2216/i0031-8884-35-6S-62.1 Dodds, 1997, Developing nutrient targets to control benthic chlorophyll levels in streams: a case study of the Clark Fork River, Water Res, 31, 1738, 10.1016/S0043-1354(96)00389-2 Dodds, 1998, Suggested classification of stream trophic state: distributions of temperate stream types by chlorophyll, total nitrogen, and phosphorus, Water Res, 32, 1455, 10.1016/S0043-1354(97)00370-9 Dodds, 2002, Nitrogen and phosphorus relationships to benthic algal biomass in temperate streams, Can J Fish Aquat Sci, 59, 865, 10.1139/f02-063 Doka, 2003, Assessing potential for recovery of biotic richness and indicator species due to changes in acidic deposition and lake pH in five areas of southeastern Canada, Environ Monit Assess, 88, 53, 10.1023/A:1025548518991 Dorsch, 1984, Congenital malformations and maternal drinking water supply in rural south Australia: a case-control study, Am J Epidemiol, 119, 473, 10.1093/oxfordjournals.aje.a113764 Dortch, 1997, Abundance and vertical flux of Pseudo-nitzschia in the northern Gulf of Mexico, Mar Ecol Prog Ser, 146, 249, 10.3354/meps146249 Downing, 2001, Predicting cyanobacteria dominance in lakes, Can J Fish Aquat Sci, 58, 1905, 10.1139/f01-143 Driscoll, 1998, Recovery of surface waters in the northeastern U.S. from decreases in atmospheric deposition of sulphur, Water Air Soil Pollut, 105, 319, 10.1023/A:1005008315977 Eddy, 1987, Nitrite and freshwater fish, Chem Ecol, 3, 1, 10.1080/02757548708070832 Elser, 1990, Phosphorus and nitrogen limitation of phytoplankton growth in the fresh-waters of North America: a review and critique of experimental enrichments, Can J Fish Aquat Sci, 47, 1468, 10.1139/f90-165 Emerson, 1975, Aqueous ammonia equilibrium calculations: effect of pH and temperature, J Fish Res Board Can, 32, 2379, 10.1139/f75-274 Environment Canada. Priority substances assessment report: ammonia in the aquatic environment. Minister of Public Works and Government Services Canada, Ottawa, ON, Canada; 2001. Epstein, 1993, Algal blooms in the spread and persistence of cholera, Biosystems, 31, 209, 10.1016/0303-2647(93)90050-M Eriksson, 1988, Preliminary characterization of a toxin isolated from the cyanobacterium Nodularia spumigena, Toxicon, 26, 161, 10.1016/0041-0101(88)90168-7 Ewell, 1986, Simultaneous evaluation of the acute effects of chemicals on seven aquatic species, Environ Toxicol Chem, 5, 831, 10.1002/etc.5620050908 Fehling, 2004, Growth and domoic acid production by Pseudo-nitzschia seriata (Bacillariophyceae) under phosphate and silicate limitation, J Phycol, 40, 674, 10.1111/j.1529-8817.2004.03213.x Fehling, 2004, Domoic acid production by Pseudo-nitzschia seriata (Bacillariophyceae) in Scottish waters, J Phycol, 40, 622, 10.1111/j.1529-8817.2004.03200.x Fisher, 1992, Nutrient limitation of phytoplankton in Chesapeake Bay, Mar Ecol Prog Ser, 82, 51, 10.3354/meps082051 Fjellheim, 1990, Acid precipitation: biological monitoring of streams and lakes, Sci Total Environ, 96, 57, 10.1016/0048-9697(90)90006-G Fogg, 1973 Francouer, 2001, Meta-analysis of lotic nutrient amendment experiments: detecting and quantifying subtle responses, J North Am Benthol Soc, 20, 358, 10.2307/1468034 Fwetrell, 2004, Drinking-water nitrate, methemoglobinemia, and global burden of disease: a discussion, Environ Health Perspect, 112, 1371, 10.1289/ehp.7216 Galloway, 2002, Reactive nitrogen and the world: 200 years of change, Ambio, 31, 64, 10.1579/0044-7447-31.2.64 Geraci, 1989, Humpback whales (Megaptera novaeangliae) fatally poisoned by dinoflagellate toxin, Can J Fish Aquat Sci, 46, 1895, 10.1139/f89-238 Gilbert, 1990, Differential effects of Anabaena affinis on cladocerans and rotifers: mechanisms and implications, Ecology, 71, 1727, 10.2307/1937581 Gilroy, 2000, Assessing potential health risks from microcystin toxins in blue-green algae dietary supplements, Environ Health Perspect, 108, 435, 10.1289/ehp.00108435 Giovannardi, 1999, Toxic cyanobacterial blooms in Lake Varese (Italy): a multidisciplinary approach, Environ Toxicol, 14, 127, 10.1002/(SICI)1522-7278(199902)14:1<127::AID-TOX16>3.0.CO;2-P Glasgow, 1995, Insidious effects of a toxic dinoflagellate on fish survival and human health, J Toxicol Environ Health, 46, 101, 10.1080/15287399509532051 Glasgow, 2001, Field ecology of toxic Pfiesteria complex species and a conservative analysis of their role in estuarine fish kills, Environ Health Perspect, 109, 715, 10.2307/3454919 1993 Graham, 2004, Environmental factors influencing microcystin distribution and concentration in the Midwestern United States, Water Res, 38, 4395, 10.1016/j.watres.2004.08.004 1990 Greer, 2005, Infant methemoglobinemia: the role of dietary nitrate in food and water, Pediatrics, 116, 784, 10.1542/peds.2005-1497 Griffith, 1994, Fungal biomass and leaf litter processing in streams of different water chemistry, Hydrobiologia, 294, 51, 10.1007/BF00017625 Groom, 1989, Food quality for detritivores in streams of contrasting pH, J Anim Ecol, 58, 863, 10.2307/5129 Gulland, 2002, Domoic acid toxicity in California sea lions (Zalophus californianus): clinical signs, treatment and survival, Vet Rec, 150, 475, 10.1136/vr.150.15.475 Gupta, 2000, Recurrent acute respiratory infections in areas with high nitrate concentrations in drinking water, Environ Health Perspect, 108, 363, 10.1289/ehp.00108363 Gutzmer, 1985, Nitrite toxicity to the crayfish Procambarus clarkii, Bull Environ Contam Toxicol, 34, 369, 10.1007/BF01609747 Hallegraeff, 1993, A review of harmful algal blooms and their apparent global increase, Phycologia, 32, 79, 10.2216/i0031-8884-32-2-79.1 Harper, 1992 Harris, 1991, The effects of nitrite on chloride regulation in the crayfish Pacifastacus leniusculus Dana (Crustacea Decapoda), J Comp Physiol, 161B, 199 Hecnar, 1995, Acute and chronic toxicity of ammonium nitrate fertilizer to amphibians from southern Ontario, Environ Toxicol Chem, 14, 2131, 10.1002/etc.5620141217 Herbert, 1965, The susceptibility of salmonid fish to poisons under estuarine conditions. II. Ammonium chloride, Int J Air Water Pollut, 9, 89 Hickey, 1999, Chronic toxicity of ammonia to the freshwater bivalve Sphaerium novaezelandiae, Arch Environ Contam Toxicol, 36, 38, 10.1007/s002449900440 Hickey, 1994, Toxicity of ammonia to nine native New Zealand freshwater invertebrate species, Arch Environ Contam Toxicol, 26, 292, 10.1007/BF00203554 Hildrew, 1984, Cellulolytic decomposition in streams of contrasting pH and its relationship with invertebrate community structure, Freshw Biol, 14, 323, 10.1111/j.1365-2427.1984.tb00045.x Hitzfeld, 2000, Cyanobacterial toxins: removal during water treatment, and human risk assessment, Environ Health Perspect, 108, 113, 10.2307/3454636 Hoagland, 2002, The economic effects of harmful algal blooms in the United States: estimates, assessment issues, and information needs, Estuaries, 25, 819, 10.1007/BF02804908 Horstman, 1991, Red tides in False Bay, 1959–1989, with particular reference to blooms of Gymnodinium sp, Trans R Soc S Afr, 47, 611 Howarth, 1988, Nutrient limitation of net primary production in marine ecosystems, Ann Rev Ecolog Syst, 19, 89, 10.1146/annurev.es.19.110188.000513 Howarth, 2000, Nutrient pollution of coastal rivers, bays, and seas, Iss Ecol, 7, 1 Huckabee, 1989, An assessment of the ecological effects of acidic deposition, Arch Environ Contam Toxicol, 18, 3, 10.1007/BF01056188 Hudnell, 2005, Chronic biotoxin-associated illness: multiple-system symptoms, a vision deficit, and effective treatment, Neurotoxicol Teratol, 27, 733, 10.1016/j.ntt.2005.06.010 Huntley, 1987, Importance of food quality in determining development and survival of Calanus pacificus (Copepoda: Calanoida), Mar Biol, 95, 103, 10.1007/BF00447491 Irwin, 1989, Acid rain: emissions and deposition, Arch Environ Contam Toxicol, 18, 95, 10.1007/BF01056194 Iverson, 1989, Domoic acid poisoning and mussel-associated intoxication: preliminary investigations into the response of mice and rats of toxic mussel extract, Food Chem Toxicol, 27, 377, 10.1016/0278-6915(89)90143-9 Jensen, 1996, Uptake, elimination and effects of nitrite and nitrate in freshwater crayfish (Astacus astacus), Aquat Toxicol, 34, 95, 10.1016/0166-445X(95)00030-8 Jensen, 2003, Nitrite disrupts multiple physiological functions in aquatic animals, Comp Biochem Physiol, 135A, 9, 10.1016/S1095-6433(02)00323-9 Johansson, 2001, Comparison of nitrate tolerance between different populations of the common frog, Rana temporaria, Aquat Toxicol, 54, 1, 10.1016/S0166-445X(00)00182-X Kelso, 1999, Toxicity of nitrite in freshwater invertebrates, 175 Kincheloe, 1979, Tolerance of developing salmonid eggs and fry to nitrate exposure, Bull Environ Contam Toxicol, 23, 575, 10.1007/BF01770006 1984 Knobeloch, 2000, Blue babies and nitrate-contaminated well water, Environ Health Perspect, 108, 675, 10.1289/ehp.00108675 Koop, 2001, ENCORE: the effect of nutrient enrichment on coral reefs. Synthesis of results and conclusions, Mar Pollut Bull, 42, 91, 10.1016/S0025-326X(00)00181-8 Kopáèek, 2001, Natural inactivation of phosphorus by aluminum in atmospherically acidified water bodies, Water Res, 35, 3783, 10.1016/S0043-1354(01)00112-9 Kopáèek, 2004, Nutrient cycling in a strongly acidified mesotrophic lake, Limnol Oceanogr, 49, 1202, 10.4319/lo.2004.49.4.1202 Krause-Dellin, 1986, Cladoceran remains as indicators of lake acidification, Hydrobiologia, 143, 129, 10.1007/BF00026655 Landsberg, 2002, The effects of harmful algal blooms on aquatic organisms, Rev Fish Sci, 10, 113, 10.1080/20026491051695 Lassus, 1999, Effect of a continuous supply of the toxic dinoflagellate Alexandrium minutum Balim on the feeding behavior of the Pacific oyster (Crassostrea gigas Thunberg), J Shellfish Res, 18, 211 Lefebvre, 2001, Tissue distribution and neurotoxic effects of domoic acid in a prominent vector species, the northern anchovy Engraulis mordax, Mar Biol, 138, 693, 10.1007/s002270000509 Lefebvre, 2002, From sanddabs to blue whales: the pervasiveness of domoic acid, Toxicon, 40, 971, 10.1016/S0041-0101(02)00093-4 Lesser, 1993, Effects of toxic dinoflagellates on clearance rates and survival in juvenile bivalve molluscs, J Shellfish Res, 12, 377 Levin, 2003, Learning impairment caused by a toxin produced by Pfiesteria piscicida infused into the hippocampus of rats, Neurotoxicol Teratol, 25, 419, 10.1016/S0892-0362(03)00011-4 Lewis, 1986, Toxicity of nitrite to fish: a review, Trans Am Fish Soc, 115, 183, 10.1577/1548-8659(1986)115<183:TONTF>2.0.CO;2 Locke, 1991, Zooplankton responses to acidification: a review of laboratory bioassays, Water Air Soil Pollut, 60, 135, 10.1007/BF00293971 Luca, 1987, In vivo and in vitro cytogenetic damage induced by sodium nitrite, Mutat Res, 189, 333, 10.1016/0165-1218(87)90065-6 Lush, 1996, High toxicity of the red tide dinoflagellate Alexandrium minutum to the brine shrimp Artemia salina, 389 Main, 1977, Sheep mortalities associated with the blue-green alga Nodularia spumigena, Aust Vet J, 53, 578, 10.1111/j.1751-0813.1977.tb15830.x Manahan, 1992 Mann, 1998, Global scale temperature patterns and climate forcing over the past six centuries, Nature, 392, 779, 10.1038/33859 Marchetti, 2004, Environmental conditions and phytoplankton dynamics associated with Pseudo-nitzschia abundance and domoic acid in the Juan de Fuca eddy, Mar Ecol Prog Ser, 281, 1, 10.3354/meps281001 Margalef, 1983 Mason, 1989, Introduction: the causes and consequences of surface water acidification, 1 Matsunaga, 1989, Anatoxin-a(s), a potent anticholinesterase from Anabaena flos-aquae, J Am Chem Soc, 111, 8021, 10.1021/ja00202a057 Meriläinen, 1990, Benthic invertebrates in relation to acidity in Finnish forest lakes, 1029 Meybeck M, Chapman DV, Helmer R. Global freshwater quality: a first assessment. World Health Organization and United Nations Environmental Program. Blackwell, Oxford, 1989. Ministry of Agriculture, Fisheries and Food, 1993 1989 Muir, 1991, Nitrate toxicity to Penaeus monodon protozoea, Mar Biol, 108, 67, 10.1007/BF01313472 Mummert, 2003, Sensitivity of juvenile freshwater mussels (Lampsilis fasciola, Villosa iris) to total and unionized ammonia, Environ Toxicol Chem, 22, 2545, 10.1897/02-341 Nash, 1993, Water quality and health, 25 National Research Council, 2000 Negri, 1995, Bioaccumulation of paralytic shellfish poisoning (PSP) toxins from the cyanobacterium Anabaena circinalis by the freshwater mussel Alathyria condola, Toxicon, 33, 667, 10.1016/0041-0101(94)00180-G 1981 Nelson, 1991, The effects of acidification on the geochemistry of Al, Cd, Pb and Hg in freshwater environments: a literature review, Environ Pollut, 71, 91, 10.1016/0269-7491(91)90030-Z Newton, 2003, Effects of ammonia on juvenile unionid mussels (Lampsilis cardium) in laboratory sediment tests, Environ Toxicol Chem, 22, 2554, 10.1897/02-342 Nixon, 1995, Coastal marine eutrophication: a definition, social causes, and future concerns, Ophelia, 41, 199, 10.1080/00785236.1995.10422044 Noga, 1996, Novel toxic dinoflagellate causes epidemic disease in estuarine fish, Mar Pollut Bull, 32, 219, 10.1016/0025-326X(95)00114-3 OECD, 1982, Eutrophication of waters: monitoring, assessment and control Ormerod, 1990, Restoring acidified streams in upland Wales: a modelling comparison of the chemical and biological effects of liming and reduced sulphate deposition, Environ Pollut, 64, 67, 10.1016/0269-7491(90)90096-U Ortiz, 1993, Acute toxicity of sulfide and lower pH in cultured rainbow trout and coho salmon, Bull Environ Contam Toxicol, 50, 164, 10.1007/BF00196556 Paerl, 1997, Coastal eutrophication and harmful algal blooms: importance of atmospheric deposition and groundwater as “new” nitrogen and other nutrient sources, Limnol Oceanogr, 42, 1154, 10.4319/lo.1997.42.5_part_2.1154 Paerl, 1999, Anthropogenically-derived atmospheric nitrogen deposition, marine eutrophication and harmful algal bloom expansion: is there a link?, Ambio, 28, 307 Paerl, 2002, Atmospheric deposition of nitrogen: implications for nutrient over-enrichment of coastal waters, Estuaries, 25, 677, 10.1007/BF02804899 Pan, 2001, Pseudo-nitzschia cf. pseudodelicatissima: a confirmed producer of domoic acid from the northern Gulf of Mexico, Mar Ecol Pog Ser, 220, 83, 10.3354/meps220083 Parslow, 1997, Incidence of childhood diabetes mellitus in Yorkshire, northern England, is associated with nitrate in drinking water: an ecological analysis, Diabetologia, 40, 550, 10.1007/s001250050714 Parsons, 2002, Sedimentological evidence of an increase in Pseudo-nitzschia (Bacillariophyceae) abundance in response to coastal eutrophication, Limnol Oceanogr, 47, 551, 10.4319/lo.2002.47.2.0551 Persson, 1984, Potentially toxic blue-green algae (cianobacteria) in Finnish natural waters, Aqua Fen, 14, 147 Philips, 2002, Origin, causes and effects of increased nitrite concentrations in aquatic environments, Rev Environ Sci Biotechnol, 1, 115, 10.1023/A:1020892826575 Rabalais, 2002, Nitrogen in aquatic ecosystems, Ambio, 31, 102, 10.1579/0044-7447-31.2.102 2002, vol. 25 Rabalais, 2002, Nutrient-enhanced productivity in the northern Gulf of Mexico: past, present and future, Hydrobiologia, 475, 39, 10.1023/A:1020388503274 1998 Reigman, 1998, Species composition of harmful algal blooms in relation to macronutrient dynamics, 475 Rejmankova, 1991, Multivariate analysis of relationships between habitats, environmental factors and occurrence of Anopheline mosquito larvae Anopheles albimanus and A. pseudopunctipennis in southern Chiapas, Mexico, J Appl Ecol, 28, 827, 10.2307/2404210 Reynolds, 1998, What factors influence the species composition of phytoplankton in lakes of different trophic status?, Hydrobiologia, 369/370, 11, 10.1023/A:1017062213207 Rice, 1980, Survival, size, and emergence of pink salmon, Oncorhynchus gorbuscha, alevins after short- and long-term exposures to ammonia, Fish Bull, 78, 641 Richardson, 1997, Acute ammonia toxicity for eight New Zealand indigenous freshwater species, NZ J Mar Freshw Res, 31, 185, 10.1080/00288330.1997.9516757 Richardson, 1997, Harmful or exceptional phytoplankton blooms in the marine ecosystem, Adv Mar Biol, 31, 301, 10.1016/S0065-2881(08)60225-4 Riddolls, 1985, Aspects of nitrogen fixation in Lough Neagh. I. Acetylene reduction and the frequency of Aphanizomenon flos-aquae heterocysts, Freshw Biol, 15, 289, 10.1111/j.1365-2427.1985.tb00201.x Rodger, 1994, Cyanobacterial (blue-green algal) bloom associated with pathology in brown trout, Salmo trutta L., in Loch Leven, Scotland, J Fish Dis, 17, 177, 10.1111/j.1365-2761.1994.tb00211.x Rouse, 1995, Toxicity of ammonia and nitrite to hatching redclaw crayfish, Cherax quadricarinatus, Freshw Crayfish, 10, 298 Rudd, 1988, Disruption of the nitrogen cycle in acidified lakes, Science, 240, 1515, 10.1126/science.240.4858.1515 Rudd, 1990, A comparison of the acidification efficiencies of nitric and sulfuric acids by two whole-lake addition experiments, Limnol Oceanogr, 35, 663, 10.4319/lo.1990.35.3.0663 Russo, 1985, Ammonia, nitrite and nitrate, 455 Russo, 1977, The acute toxicity of nitrite to fishes, 118 Russo, 1981, Acute toxicity of nitrite to rainbow trout (Salmo gairdneri): effects of pH, nitrite species, and anion species, Can J Fish Aquat Sci, 38, 387, 10.1139/f81-054 Sasner, 1984, Studies on Aphanizomenon and Microcystis toxins, 391 Schindler, 1977, Evolution of phosphorus limitation in lakes, Science, 195, 260, 10.1126/science.195.4275.260 Schindler, 1988, Effects of acid rain on freshwater ecosystems, Science, 239, 149, 10.1126/science.239.4836.149 Schindler, 1989, Losses of biota from America aquatic communities due to acid rain, Environ Monit Assess, 12, 269, 10.1007/BF00394806 Schindler, 1991, Freshwater acidification, reversibility and recovery: comparisons of experimental and atmospherical acidified lakes, Proc R Soc Edinb, 878, 193 Scholin, 2000, Mortality of sea lions along the central California coast linked to a toxic diatom bloom, Nature, 403, 80, 10.1038/47481 Schuurkes, 1988, The role of external ammonium inputs in freshwater acidification, Schweiz Z Hydrol, 50, 71, 10.1007/BF02538372 Schuytema, 1999, Comparative toxicity of ammonium and nitrate compounds to Pacific treefrog and African clawed frog tadpoles, Environ Toxicol Chem, 18, 2251, 10.1002/etc.5620181019 Scott, 2000, Acute and chronic toxicity of nitrate to fathead minnows (Pimephales promelas), Ceriodaphnia dubia and Daphnia magna, Environ Toxicol Chem, 19, 2918, 10.1897/1551-5028(2000)019<2918:AACTON>2.0.CO;2 Sellner, 1996, Copepod interactions with toxic and nontoxic cyanobacteria from the Gulf of Finland, Phycologia, 35, 177, 10.2216/i0031-8884-35-6S-177.1 Sellner, 1997, Physiology, ecology, and toxic properties of marine cyanobacteria blooms, Limnol Oceanogr, 42, 1089, 10.4319/lo.1997.42.5_part_2.1089 Sharma, 1977, Nitrification and nitrogen removal, Water Res, 11, 897, 10.1016/0043-1354(77)90078-1 Shaw, 1997, Feeding deterrent and toxicity effects of apofucoxanthinoids and phycotoxins on a marine copepod (Tigriopus californicus), Mar Biol, 128, 273, 10.1007/s002270050092 Sierra Beltran, 1997, Sea bird mortality at Cabo San Lucas, Mexico: evidence that toxic diatom blooms are spreading, Toxicon, 35, 447, 10.1016/S0041-0101(96)00140-7 Skjelkvale, 2001, Trends in surface water acidification in Europe and North America (1989–1998), Water Air Soil Pollut, 130, 787, 10.1023/A:1013806223310 1993 Smil, 2001 Smith, 2003, Eutrophication of freshwater and coastal marine ecosystems: a global problem, Environ Sci Pollut R, 10, 126, 10.1065/espr2002.12.142 Smith, 1999, Eutrophication: impacts of excess nutrient inputs on freshwater, marine, and terrestrial ecosystems, Environ Pollut, 100, 179, 10.1016/S0269-7491(99)00091-3 1984 Sprenger, 1989, Relationship between concentrations of aluminium, cadmium, lead, and zinc in water, sediments, and aquatic macrophytes in six acidic lakes, Arch Environ Contam Toxicol, 18, 225, 10.1007/BF01056207 Spry, 1991, Metal bioavailability and toxicity to fish in low-alkalinity lakes: a critical review, Environ Pollut, 71, 243, 10.1016/0269-7491(91)90034-T Steinheimer, 1998, Agricultural chemical movement through a field-sized watershed in Iowa: subsurface hydrology and distribution of nitrate in groundwater, Environ Sci Technol, 32, 1039, 10.1021/es970598j Stoddard, 1999, Regional trends in aquatic recovery from acidification in North America and Europe, Nature, 401, 575, 10.1038/44114 Stumm, 1996 Swedish EPA, 2000, Environmental quality criteria: coasts and seas, vol. 5052 Tahon, 1988, The reaction of nitrite with the haemocyanin of Astacus leptodactylus, Biochem J, 249, 891, 10.1042/bj2490891 Teixera, 1993, Gastroenteritis epidemic in the area of the Itaparica Dam, Bahia Brazil, Bull Pan Am Health Organ, 27, 244 Teng, 1998, Effects of environmental factors on abundance of Anopheles minimus (Diptera: Culicidae) larvae and their seasonal fluctuation in Taiwan, Environ Entomol, 27, 324, 10.1093/ee/27.2.324 Tester, 1991, An expatriate red tide bloom: transport, distribution, and persistence, Limnol Oceanogr, 36, 1053, 10.4319/lo.1991.36.5.1053 Thessen, 2005, Effect of salinity on Pseudo-nitzschia species (Bacillariophyceae) growth and distribution, J Phycol, 41, 21, 10.1111/j.1529-8817.2005.04077.x Thurston, 1978, Acute toxicity of ammonia and nitrite to cutthroat trout fry, Trans Am Fish Soc, 107, 361, 10.1577/1548-8659(1978)107<361:ATOAAN>2.0.CO;2 Todd, 1989, Preliminary estimates of costs of food-borne disease in the United States, J Food Prot, 52, 595, 10.4315/0362-028X-52.8.595 Todd, 1993, Domoic acid and amnesic shellfish poisoning: a review, J Food Prot, 56, 69, 10.4315/0362-028X-56.1.69 Tomasso, 1980, Effects of environmental pH and calcium on ammonia toxicity in channel catfish, Trans Am Fish Soc, 109, 229, 10.1577/1548-8659(1980)109<229:EOEPAC>2.0.CO;2 Tomasso, 1979, Chloride inhibition of nitrite-induced methemoglobinemia in channel catfish (Ictalurus punctatus), J Fish Res Board Can, 36, 1141, 10.1139/f79-160 Toranzo, 1990, Mortality associated with a cyanobacterial bloom in farmed rainbow trout in Galicia (northwest Spain), Bull Eur Assoc Fish Pathol, 10, 106 Toth, 2000, North Carolina pest news, NC Coop Ext Serv, 16 Townsend, 2003, Human health effects of a changing global nitrogen cycle, Front Ecol Environ, 1, 240, 10.1890/1540-9295(2003)001[0240:HHEOAC]2.0.CO;2 Turner, 1996, Do toxic phytoplankton reduce egg production and hatching success of the copepod Acartia tonsa?, EOS, 76 Turner, 2002, Element ratios and aquatic food webs, Estuaries, 25, 694, 10.1007/BF02804900 Turner, 1998, Fluctuating silicate: nitrate ratios and coastal plankton food webs, Proc Natl Acad Sci USA, 95, 13048, 10.1073/pnas.95.22.13048 Turner, 2003, Global patterns of dissolved N, P and Si in large rivers, Biogeochemistry, 64, 297, 10.1023/A:1024960007569 Turner, 2003, Future aquatic nutrient limitations, Mar Pollut Bull, 46, 1032, 10.1016/S0025-326X(03)00049-3 Ulrich, 2000, Evidence for aluminium precipitation and phosphorus inactivation in acidified watershed-reservoir ecosystems, Sil Gab, 4, 125 US Environmental Protection Agency, 1986 US Environmental Protection Agency, 1999 US EPA. http://www.epa.gov/waterscience/criteria/nutrient/guidance/index.html; 2002. Van den Bergh, 2002, Exotic harmful algae in marine ecosystems: an integrated biological–economic–legal analysis of impacts and policies, Mar Pollut, 26, 59, 10.1016/S0308-597X(01)00032-X Van Dolah, 2000, Marine algal toxins: origins, health effects, and their increased occurrence, Environ Health Perspect, 108, 133, 10.2307/3454638 Van Dolah, 2001, Health and ecological impacts of harmful algal blooms: risk assessment needs, Hum Ecol Risk Assess, 7, 1329, 10.1080/20018091095032 Van Maanen, 1994, Consumption of drinking waters with high nitrate levels causes hypertrophy of the thyroid, Toxicol Lett, 72, 365, 10.1016/0378-4274(94)90050-7 Van Maanen, 1996, Nitrate contamination of drinking water: relationship with HPRT variant frequency in lymphocyte DNA and urinary excretion of N-nitrosamines, Environ Health Perspect, 104, 522, 10.1289/ehp.96104522 Van Maanen, 2000, Does the risk of childhood diabetes mellitus require revision of the guideline values for nitrate in drinking water?, Environ Health Perspect, 108, 457, 10.1289/ehp.00108457 Virtanen, 1994, Nitrate and nitrite intake and the risk for Type 1 diabetes in Finnish children, Diabet Med, 11, 656, 10.1111/j.1464-5491.1994.tb00328.x Vitousek, 1997, Human alteration of the global nitrogen cycle: sources and consequences, Ecol Appl, 7, 737 1992 Walker, 1991, Nutrient dynamics, bacterial-populations, and mosquito productivity in tree hole ecosystems and microcosms, Ecology, 72, 1529, 10.2307/1940953 Ward, 1996, Drinking water nitrate and the risk of non-Hodgkin's lymphoma, Epidemiology, 7, 465, 10.1097/00001648-199609000-00002 Westin, 1974, Nitrate and nitrite toxicity to salmonid fishes, Prog Fish-Cult, 36, 86, 10.1577/1548-8659(1974)36[86:NANTTS]2.0.CO;2 Wetzel, 2001 Weyer, 2001, Municipal drinking water nitrate level and cancer risk in older women: the Iowa Women's Health Study, Epidemiology, 12, 327, 10.1097/00001648-200105000-00013 Williams, 1986, Studies on the acute toxicity of pollutants to freshwater macroinvertebrates. 3. Ammonia, Arch Hydrobiol, 106, 61, 10.1127/archiv-hydrobiol/106/1986/61 Wolfe, 2002, Reactive nitrogen and human health: acute and long-term implications, Ambio, 31, 120, 10.1579/0044-7447-31.2.120 Work, 1992, Epidemiology of domoic acid poisoning in brown pelicans (Pelecanus occidentalis) and Brandt's cormorants (Phalacrocorax penicillatus) in California, J Zoo Wildl Med, 24, 54 World Health Organization, 1996, Guidelines for drinking-water quality Wright, 1989, Identification of domic acid, a neuroexcitatory amino acid in toxic mussels from eastern Prince Edward Island, Can J Chem, 67, 481, 10.1139/v89-075