Equivalence testing the easy way

V. Luzar-Stiffler1, C. Stiffler2
1Univ. Comput. Centre, Zagreb, Croatia
2CAIR Research Center, Zagreb, Croatia

Tóm tắt

The purpose of the article is to demonstrate an equivalence testing software application written under SAS Institute software designed for use by pharmaceutical and other medical research professionals. Besides making the entire equivalence testing procedure easier and more efficient, the application "EquivEasy" offers three main advantages over similar software: (a) testing for 3/spl times/3 in addition to 2/spl times/2 crossover designs, (b) familiar SAS user environment, and (c) export flexibility (MS Word, PDF, HTML). Two case studies are presented with report results provided in tabular and graphical form.

Từ khóa

#Synthetic aperture sonar #Software testing #Application software #Pharmaceuticals #Performance evaluation #HTML #Medical tests #Software design #Clinical trials #Software performance

Tài liệu tham khảo

chow, 2000, Design and Analysis of Bioavailability and Bioequivalence Studies 10.1080/10543409708835162 0, EquivTest berger, 1996, Bioequivalence trials, intersection-union tests and equivalence confidence sets (with discussion), Statistical Science, 11, 283, 10.1214/ss/1032280304 schuirmann, 1981, On hypothesis testing to determine if the mean of a normal distribution is contained in a known interval, Biometrics, 37, 617 hauschke, 1990, A distribution-free procedure for the statistical analysis of bioequivalence studies, Int J of Clin Pharm Therapy and Toxic, 28, 72 fieller, 1954, Some problems in interval estimation, J R Stat Soc B, 16, 175 10.1137/1.9781611970319 10.2307/2333709 10.1007/BF01068419 1992, Guidance on Statistical Procedures for Bioequivalence Using A Standard Two-treatment Crossover Design