Cefiderocol MIC quality control ranges in iron-depleted cation-adjusted Mueller–Hinton broth using a CLSI M23-A4 multi-laboratory study design

CDC Clinical and Laboratory Standards Institute (CLSI), 2015 Clinical and Laboratory Standards Institute (CLSI), 2016 Clinical and Laboratory Standards Institute (CLSI), 2016 Ito, 2016, In vitro antimicrobial activity of S-649266, a catechol-substituted siderophore cephalosporin, when tested against non-fermenting gram-negative bacteria, J Antimicrob Chemother, 71, 670, 10.1093/jac/dkv402 Ito, 2016, Siderophore cephalosporin cefiderocol utilizes ferric iron transporter systems for antibacterial activity against Pseudomonas aeruginosa, Antimicrob Agents Chemother, 60, 7396, 10.1128/AAC.01405-16 Ito, 2015, S-649266, a novel sidepophore cephalosporin: Binding affinity to PBP and bactericidal activity Ito-Horiyama, 2016, Stability of novel siderophore cephalosporin S-649266 against clinically relevant carbapenemases, Antimicrob Agents Chemother, 60, 4384, 10.1128/AAC.03098-15 Kohira, 2016, In vitro antimicrobial activity of a siderophore cephalosporin, S-649266, against Enterobacteriaceae clinical isolates, including carbapenem-resistant strains, Antimicrob Agents Chemother, 60, 729, 10.1128/AAC.01695-15 Mollmann, 2009, Siderophores as drug delivery agents: application of the "Trojan horse" strategy, 22, 615 Penwell, 2012, The Acinetobacter baumannii entA gene located outside the acinetobactin cluster is critical for siderophore production, iron acquisition and virulence, PLoS One, 7, e36493, 10.1371/journal.pone.0036493 Shields, 2016, Clinical outcomes, drug toxicity and emergence of ceftazidime-avibactam resistance among patients treated for carbapenem-resistant Enterobacteriaceae infections, Clin Infect Dis, 63, 1615, 10.1093/cid/ciw636 Spellberg, 2016, Editorial commentary: ceftazidime-avibactam and carbapenem-resistant enterobacteriaceae: "We're gonna need a bigger boat", Clin Infect Dis, 63, 1619, 10.1093/cid/ciw639 The White House, 2014 Tsuji, 2014, S-649266, a novel siderophore cephalosporin: mechanisms of enahanced activity and beta-lactamase stability Turnidge, 2007, Statistical methods for establishing quality control ranges for antibacterial agents in clinical and laboratory standards Institute susceptibility testing, Antimicrob Agents Chemother, 51, 2483, 10.1128/AAC.01457-06 Watkins, 2013, Novel beta-lactamase inhibitors: a therapeutic hope against the scourge of multidrug resistance, Front Microbiol, 4, 392, 10.3389/fmicb.2013.00392