Organoids from adult liver and pancreas: Stem cell biology and biomedical utility
Tài liệu tham khảo
Akhurst, 2001, A modified choline-deficient, ethionine-supplemented diet protocol effectively induces oval cells in mouse liver, Hepatology, 34, 519, 10.1053/jhep.2001.26751
Al-Hasani, 2013, Adult duct-lining cells can reprogram into β-like cells able to counter repeated cycles of toxin-induced diabetes, Dev. Cell, 26, 86, 10.1016/j.devcel.2013.05.018
Aloia, 2016, Cellular plasticity in the adult liver and stomach, J. Physiol, 10.1113/JP271769
Apelqvist, 1999, Notch signalling controls pancreatic cell differentiation, Nature, 400, 877, 10.1038/23716
Asrani, 2013, Underestimation of liver-related mortality in the United States, Gastroenterology, 145, 10.1053/j.gastro.2013.04.005
Assy, 2007, Randomized controlled trial of total immunosuppression withdrawal in liver transplant recipients: role of ursodeoxycholic acid, Transplantation, 83, 1571, 10.1097/01.tp.0000266678.32250.76
Barker, 2010, Lgr5(+ve) stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro, Cell Stem Cell, 6, 25, 10.1016/j.stem.2009.11.013
Beer, 2016, Centroacinar cells: at the center of pancreas regeneration, Dev. Biol., 413, 8, 10.1016/j.ydbio.2016.02.027
Bhushan, 2001, Fgf10 is essential for maintaining the proliferative capacity of epithelial progenitor cells during early pancreatic organogenesis, Development, 128, 5109, 10.1242/dev.128.24.5109
Blanpain, 2014, Stem cell plasticity. Plasticity of epithelial stem cells in tissue regeneration, Science, 344, 1242281, 10.1126/science.1242281
Boj, 2015, Organoid models of human and mouse ductal pancreatic cancer, Cell, 160, 324, 10.1016/j.cell.2014.12.021
Boulter, 2012, Macrophage-derived Wnt opposes Notch signaling to specify hepatic progenitor cell fate in chronic liver disease, Nat. Med., 18, 572, 10.1038/nm.2667
Byass, 2014, The global burden of liver disease: a challenge for methods and for public health, BMC Med., 12, 159, 10.1186/s12916-014-0159-5
Campbell, 2005, Platelet-derived growth factor C induces liver fibrosis, steatosis, and hepatocellular carcinoma, Proc. Natl. Acad. Sci. USA, 102, 3389, 10.1073/pnas.0409722102
Chen, 1954, The cultivation in fluid medium of organised liver, pancreas and other tissues of foetal rats, Exp. Cell Res., 7, 518, 10.1016/S0014-4827(54)80096-6
Chen, 2012, HSCs play a distinct role in different phases of oval cell-mediated liver regeneration, Cell Biochem. Funct., 30, 588, 10.1002/cbf.2838
Cheng, 2012, Low incidence of DNA sequence variation in human induced pluripotent stem cells generated by nonintegrating plasmid expression, Cell Stem Cell, 10, 337, 10.1016/j.stem.2012.01.005
Collombat, 2009, The ectopic expression of Pax4 in the mouse pancreas converts progenitor cells into alpha and subsequently beta cells, Cell, 138, 449, 10.1016/j.cell.2009.05.035
de Lau, 2014, The R-spondin/Lgr5/Rnf43 module: regulator of Wnt signal strength, Genes Dev., 28, 305, 10.1101/gad.235473.113
Deutsch, 2001, A bipotential precursor population for pancreas and liver within the embryonic endoderm, Development, 128, 871, 10.1242/dev.128.6.871
Dholakia, 2016, Advances in pancreas transplantation, J. R. Soc. Med., 109, 141, 10.1177/0141076816636369
Ding, 2010, Inductive angiocrine signals from sinusoidal endothelium are required for liver regeneration, Nature, 468, 310, 10.1038/nature09493
Dor, 2004, Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation, Nature, 429, 41, 10.1038/nature02520
Dorrell, 2011, Prospective isolation of a bipotential clonogenic liver progenitor cell in adult mice, Genes Dev., 25, 1193, 10.1101/gad.2029411
Dorrell, 2014, The organoid-initiating cells in mouse pancreas and liver are phenotypically and functionally similar, Stem Cell Res., 13, 275, 10.1016/j.scr.2014.07.006
Duncan, 2009, Stem cells and liver regeneration, Gastroenterology, 137, 466, 10.1053/j.gastro.2009.05.044
Elsässer, 1986, Time course and cellular source of pancreatic regeneration following acute pancreatitis in the rat, Pancreas, 1, 421, 10.1097/00006676-198609000-00006
Farber, 1956, Similarities in the sequence of early histological changes induced in the liver of the rat by ethionine, 2-acetylamino-fluorene, and 3′-methyl-4-dimethylaminoazobenzene, Cancer Res., 16, 142
Fausto, 2003, The Role of Hepatocytes and Oval Cells In Liver Regeneration and Repopulation, Mech Dev., 120, 117, 10.1016/S0925-4773(02)00338-6
Feng, 2012, Interleukin-22 promotes proliferation of liver stem/progenitor cells in mice and patients with chronic hepatitis B virus infection, Gastroenterology, 143, 188, 10.1053/j.gastro.2012.03.044
Font-Burgada, 2015, Hybrid periportal hepatocytes regenerate the injured liver without giving rise to cancer, Cell, 162, 766, 10.1016/j.cell.2015.07.026
Fraczek, 2013, Primary hepatocyte cultures for pharmaco-toxicological studies: at the busy crossroad of various anti-dedifferentiation strategies, Arch. Toxicol., 87, 577, 10.1007/s00204-012-0983-3
Furuyama, 2011, Continuous cell supply from a Sox9-expressing progenitor zone in adult liver, exocrine pancreas and intestine, Nat. Genet., 43, 34, 10.1038/ng.722
Ghaneh, 2008, Biology and management of pancreatic cancer, Postgrad. Med. J., 84, 478, 10.1136/gut.2006.103333
Gianani, 2010, Dimorphic histopathology of long-standing childhood-onset diabetes, Diabetologia, 53, 690, 10.1007/s00125-009-1642-y
Gittes, 1996, Lineage-specific morphogenesis in the developing pancreas: role of mesenchymal factors, Development, 122, 439, 10.1242/dev.122.2.439
Gouzi, 2011, Neurogenin3 initiates stepwise delamination of differentiating endocrine cells during pancreas development, Dev. Dyn., 240, 589, 10.1002/dvdy.22544
Gradwohl, 2000, neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas, Proc. Natl. Acad. Sci. USA, 97, 1607, 10.1073/pnas.97.4.1607
Greggio, 2013, Artificial three-dimensional niches deconstruct pancreas development in vitro, Development, 140, 4452, 10.1242/dev.096628
Gu, 2002, Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors, Development, 129, 2447, 10.1242/dev.129.10.2447
Gualdi, 1996, Hepatic specification of the gut endoderm in vitro: cell signaling and transcriptional control, Genes Dev., 10, 1670, 10.1101/gad.10.13.1670
Hindley, 2014, The plastic liver: differentiated cells, stem cells, every cell?, J. Clin. Investig., 124, 5099, 10.1172/JCI78372
Hoppo, 2004, Thy1-positive mesenchymal cells promote the maturation of CD49f-positive hepatic progenitor cells in the mouse fetal liver, Hepatology, 39, 1362, 10.1002/hep.20180
Huang, 2015, Ductal pancreatic cancer modeling and drug screening using human pluripotent stem cell- and patient-derived tumor organoids, Nat. Med., 21, 1364, 10.1038/nm.3973
Huch, 2013, In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration, Nature, 494, 247, 10.1038/nature11826
Huch, 2013, Unlimited in vitro expansion of adult bi-potent pancreas progenitors through the Lgr5/R-spondin axis, EMBO J., 32, 2708, 10.1038/emboj.2013.204
Huch, 2015, Long-term culture of genome-stable bipotent stem cells from adult human liver, Cell, 160, 299, 10.1016/j.cell.2014.11.050
Huch, 2015, Regenerative biology: the versatile and plastic liver, Nature, 517, 155, 10.1038/517155a
Huch, 2015, Modeling mouse and human development using organoid cultures, Development, 142, 3113, 10.1242/dev.118570
Huch, 2016, The plastic cellular states of liver cells: are EpCAM and Lgr5 fit for purpose?, Hepatology, 10.1002/hep.28469
Inada, 2008, Carbonic anhydrase II-positive pancreatic cells are progenitors for both endocrine and exocrine pancreas after birth, Proc. Natl. Acad. Sci. USA, 105, 19915, 10.1073/pnas.0805803105
Jennings, 2013, Development of the human pancreas from foregut to endocrine commitment, Diabetes, 62, 3514, 10.2337/db12-1479
Jensen, 2000, Control of endodermal endocrine development by Hes-1, Nat. Genet., 24, 36, 10.1038/71657
Jin, 2013, Colony-forming cells in the adult mouse pancreas are expandable in Matrigel and form endocrine/acinar colonies in laminin hydrogel, Proc. Natl. Acad. Sci. USA, 110, 3907, 10.1073/pnas.1301889110
Jin, 2014, In vitro multilineage differentiation and self-renewal of single pancreatic colony-forming cells from adult C57BL/6 mice, Stem Cells Dev., 23, 899, 10.1089/scd.2013.0466
Jung, 1999, Initiation of mammalian liver development from endoderm by fibroblast growth factors, Science, 284, 1998, 10.1126/science.284.5422.1998
Kamiya, 1999, Fetal liver development requires a paracrine action of oncostatin M through the gp130 signal transducer, EMBO J., 18, 2127, 10.1093/emboj/18.8.2127
Koo, 2014, Stem cells marked by the R-spondin receptor LGR5, Gastroenterology, 147, 289, 10.1053/j.gastro.2014.05.007
Kopinke, 2011, Lineage tracing reveals the dynamic contribution of Hes1+ cells to the developing and adult pancreas, Development, 138, 431, 10.1242/dev.053843
Kopp, 2016, Stem cells versus plasticity in liver and pancreas regeneration, Nat. Cell Biol., 18, 238, 10.1038/ncb3309
Kudira, 2016, P2X1 regulated IL-22 secretion by innate lymphoid cells is required for efficient liver regeneration, Hepatology, 63, 2004, 10.1002/hep.28492
Kuijk, 2016, Generation and characterization of rat liver stem cell lines and their engraftment in a rat model of liver failure, Sci. Rep., 6, 10.1038/srep22154
Lajtha, 1979, Stem cell concepts, Differentiation, 14, 23, 10.1111/j.1432-0436.1979.tb01007.x
Laursen, 2014, A preventable cancer, Nature, 516, S2, 10.1038/516S2a
Lee, 2013, Expansion and conversion of human pancreatic ductal cells into insulin-secreting endocrine cells, Elife, 2
Lee, 1993, Acute liver failure, N. Engl. J. Med., 329, 1862, 10.1056/NEJM199312163292508
Lindemans, 2015, Interleukin-22 promotes intestinal-stem-cell-mediated epithelial regeneration, Nature, 528, 560, 10.1038/nature16460
Lucas, 2016, Global Trends in Pancreatic Cancer Mortality From 1980 Through 2013 and Predictions for 2017, Clin. Gastroenterol. Hepatol., S1542-3565
Ma, 2010, Polyclonal origin of hormone-producing cell populations evaluated as a direct in situ demonstration in EGFP/BALB/C chimeric mice, J. Endocrinol., 207, 17, 10.1677/JOE-10-0184
Malato, 2011, Fate tracing of mature hepatocytes in mouse liver homeostasis and regeneration, J. Clin. Investig., 121, 4850, 10.1172/JCI59261
Matano, 2015, Modeling colorectal cancer using CRISPR-Cas9-mediated engineering of human intestinal organoids, Nat. Med., 21, 256, 10.1038/nm.3802
Matsui, 2002, K-Ras mediates cytokine-induced formation of E-cadherin-based adherens junctions during liver development, EMBO J., 21, 1021, 10.1093/emboj/21.5.1021
Matsumoto, 2001, Liver organogenesis promoted by endothelial cells prior to vascular function, Science, 294, 559, 10.1126/science.1063889
McCracken, 2011, Generating human intestinal tissue from pluripotent stem cells in vitro, Nat. Protoc., 6, 1920, 10.1038/nprot.2011.410
McCracken, 2014, Modelling human development and disease in pluripotent stem-cell-derived gastric organoids, Nature, 516, 400, 10.1038/nature13863
Mesa, 2015, The dynamic duo: niche/stem cell interdependency, Stem Cell Rep., 4, 961, 10.1016/j.stemcr.2015.05.001
Michalopoulos, 1997, Liver regeneration, Science, 276, 60, 10.1126/science.276.5309.60
Miyajima, 2014, Stem/progenitor cells in liver development, homeostasis, regeneration, and reprogramming, Cell Stem Cell, 14, 561, 10.1016/j.stem.2014.04.010
Miyao, 2015, Pivotal role of liver sinusoidal endothelial cells in NAFLD/NASH progression, Lab. Invest., 95, 1130, 10.1038/labinvest.2015.95
Nantasanti, 2015, Disease modeling and gene therapy of copper storage disease in canine hepatic organoids, Stem Cell Rep., 5, 895, 10.1016/j.stemcr.2015.09.002
Nibourg, 2012, Proliferative human cell sources applied as biocomponent in bioartificial livers: a review, Expert Opin. Biol. Ther., 12, 905, 10.1517/14712598.2012.685714
Onitsuka, 2010, Characterization and functional analyses of hepatic mesothelial cells in mouse liver development, Gastroenterology, 138, 1525, 10.1053/j.gastro.2009.12.059
Oshima, 2007, Isolation of mouse pancreatic ductal progenitor cells expressing CD133 and c-Met by flow cytometric cell sorting, Gastroenterology, 132, 720, 10.1053/j.gastro.2006.11.027
Paku, 2001, Origin and structural evolution of the early proliferating oval cells in rat liver, Am. J. Pathol., 158, 1313, 10.1016/S0002-9440(10)64082-5
Petersen, 1997, Bile ductular damage induced by methylene dianiline inhibits oval cell activation, Am. J. Pathol., 151, 905
Preisegger, 1999, Atypical ductular proliferation and its inhibition by transforming growth factor beta1 in the 3,5-diethoxycarbonyl-1,4-dihydrocollidine mouse model for chronic alcoholic liver disease, Lab. Investig., 79, 103
Pritchard, 2010, Hepatic fibrosis is enhanced and accompanied by robust oval cell activation after chronic carbon tetrachloride administration to Egr-1-deficient mice, Am. J. Pathol., 176, 2743, 10.2353/ajpath.2010.091186
Ritsma, 2014, Intestinal crypt homeostasis revealed at single-stem-cell level by in vivo live imaging, Nature, 507, 362, 10.1038/nature12972
Rocha, 2015, The angiocrine factor Rspondin3 is a key determinant of liver zonation, Cell Rep., 13, 1757, 10.1016/j.celrep.2015.10.049
Rodríguez-Seguel, 2013, Mutually exclusive signaling signatures define the hepatic and pancreatic progenitor cell lineage divergence, Genes Dev., 27, 1932, 10.1101/gad.220244.113
Rossi, 2001, Distinct mesodermal signals, including BMPs from the septum transversum mesenchyme, are required in combination for hepatogenesis from the endoderm, Genes Dev., 15, 1998, 10.1101/gad.904601
Sampaziotis, 2015, Cholangiocytes derived from human induced pluripotent stem cells for disease modeling and drug validation, Nat. Biotechnol., 33, 845, 10.1038/nbt.3275
Sancho, 2014, Loss of Fbw7 reprograms adult pancreatic ductal cells into α, δ, and β cells, Cell Stem Cell, 15, 139, 10.1016/j.stem.2014.06.019
Sangiorgi, 2009, Bmi1 lineage tracing identifies a self-renewing pancreatic acinar cell subpopulation capable of maintaining pancreatic organ homeostasis, Proc. Natl. Acad. Sci. USA, 106, 7101, 10.1073/pnas.0902508106
Sato, 2009, Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche, Nature, 459, 262, 10.1038/nature07935
Schaub, 2014, Evidence against a stem cell origin of new hepatocytes in a common mouse model of chronic liver injury, Cell Rep., 8, 933, 10.1016/j.celrep.2014.07.003
Schöls, 1990, Reestablishment of the heterogeneous distribution of hepatic glutamine synthetase during regeneration after CCl4-intoxication, Histochemistry, 94, 49, 10.1007/BF00266789
Schwank, 2013, Functional repair of CFTR by CRISPR/Cas9 in intestinal stem cell organoids of cystic fibrosis patients, Cell Stem Cell, 13, 653, 10.1016/j.stem.2013.11.002
Serls, 2005, Different thresholds of fibroblast growth factors pattern the ventral foregut into liver and lung, Development, 132, 35, 10.1242/dev.01570
Shin, 2011, Foxl1-Cre-marked adult hepatic progenitors have clonogenic and bilineage differentiation potential, Genes Dev., 25, 1185, 10.1101/gad.2027811
Snykers, 2009, In vitro differentiation of embryonic and adult stem cells into hepatocytes: state of the art, Stem Cells, 27, 577, 10.1634/stemcells.2008-0963
Takase, 2013, FGF7 is a functional niche signal required for stimulation of adult liver progenitor cells that support liver regeneration, Genes Dev., 27, 169, 10.1101/gad.204776.112
Takebe, 2013, Vascularized and functional human liver from an iPSC-derived organ bud transplant, Nature, 499, 481, 10.1038/nature12271
Takebe, 2015, Vascularized and complex organ buds from diverse tissues via mesenchymal cell-driven condensation, Cell Stem Cell, 16, 556, 10.1016/j.stem.2015.03.004
Teta, 2005, Very slow turnover of beta-cells in aged adult mice, Diabetes, 54, 2557, 10.2337/diabetes.54.9.2557
Teta, 2007, Growth and regeneration of adult beta cells does not involve specialized progenitors, Dev. Cell, 12, 817, 10.1016/j.devcel.2007.04.011
Van de Casteele, 2014, Partial duct ligation: β-cell proliferation and beyond, Diabetes, 63, 2567, 10.2337/db13-0831
van de Wetering, 2015, Prospective derivation of a living organoid biobank of colorectal cancer patients, Cell, 161, 933, 10.1016/j.cell.2015.03.053
Wang, 2015, Self-renewing diploid Axin2(+) cells fuel homeostatic renewal of the liver, Nature, 524, 180, 10.1038/nature14863
Watson, 2014, An in vivo model of human small intestine using pluripotent stem cells, Nat. Med., 20, 1310, 10.1038/nm.3737
Weaver, 1985, Immunocytochemical localization of insulin-immunoreactive cells in the pancreatic ducts of rats treated with trypsin inhibitor, Diabetologia, 28, 781, 10.1007/BF00265028
Westphalen, 2016, Dclk1 defines quiescent pancreatic progenitors that promote injury-induced regeneration and tumorigenesis, Cell Stem Cell, 18, 441, 10.1016/j.stem.2016.03.016
Xu, 2008, Beta cells can be generated from endogenous progenitors in injured adult mouse pancreas, Cell, 132, 197, 10.1016/j.cell.2007.12.015
Yanger, 2014, Adult hepatocytes are generated by self-duplication rather than stem cell differentiation, Cell Stem Cell, 15, 340, 10.1016/j.stem.2014.06.003
Yimlamai, 2014, Hippo pathway activity influences liver cell fate, Cell, 157, 1324, 10.1016/j.cell.2014.03.060
Zaret, 2008, Generation and regeneration of cells of the liver and pancreas, Science, 322, 1490, 10.1126/science.1161431
Zhou, 2007, A multipotent progenitor domain guides pancreatic organogenesis, Dev. Cell, 13, 103, 10.1016/j.devcel.2007.06.001
Zhou, 2008, In vivo reprogramming of adult pancreatic exocrine cells to beta-cells, Nature, 455, 627, 10.1038/nature07314
Zorn, 2009, Vertebrate endoderm development and organ formation, Annu. Rev. Cell Dev. Biol., 25, 221, 10.1146/annurev.cellbio.042308.113344