Physical activity is independently related to aerobic capacity in cystic fibrosis

European Respiratory Journal - Tập 28 Số 4 - Trang 734-739 - 2006
Helge Hebestreit1,2
1Julius-Maximilians-Universita ¨t Wu ¨rzburg, Wu ¨rzburg,
2University Children’s Hospital

Tóm tắt

It is unclear whether a relationship between physical activity (PA) and maximal oxygen uptake (V′O2,max) exists in cystic fibrosis (CF) and, if so, whether the relationship reflects a direct effect or is mediated by the effects of confounding variables, such as pulmonary or muscle function. The objective of the present study was to determine the relationship between PA andV′O2,maxin CF while adjusting for possible influences of confounding factors.In total, 36 female and 35 male patients with CF from Germany and Switzerland (aged 12–40 yrs, forced expiratory volume in one second (FEV1) 25–107% predicted) were studied. A Wingate test was employed to measure muscle power. PA was monitored for 7 days and expressed in two ways: 1) average daily accelerometer count (ADAC) and 2) time spent in moderate-to-vigorous PA (MVPA).V′O2,maxwas determined during an incremental cycle exercise test to volitional fatigue.PA was positively related toV′O2,max. In a multiple linear regression analysis, height, sex, FEV1, muscle power and ADAC (additionally explained variance 2.5%) or time spent in MVPA (additionally explained variance 3.7%) were identified as independent predictors ofV′O2,max.In conclusion, high levels of physical activity in addition to good muscular and pulmonary functions are associated with a high aerobic capacity in cystic fibrosis.

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10.1056/NEJM199212173272504

10.1378/chest.95.2.344

10.1002/ppul.10015

10.1164/rccm.2202053

10.1378/chest.80.4.392

10.1136/thx.2003.015313

10.1067/mpd.2000.103408

1984, Aust Paediatr J, 20, 297

2001, Med Sci Sports Exerc, 33, 30

10.1152/japplphysiol.00475.2004

1998, Am J Respir Crit Care Med, 157, 1145, 10.1164/ajrccm.157.4.9705023

10.1136/adc.2003.034249

10.1016/0954-6111(93)90011-N

1986, Pediatr Pulmonol, 2, 274, 10.1002/ppul.1950020505

10.1378/chest.124.6.2215

1992, Clin Sci, 83, 391, 10.1042/cs0830391

10.1378/chest.125.4.1299

10.1016/j.jpeds.2005.03.043

Lohman TG, Roche AF, Martorell R. Anthropometric standardization reference manual. Champaign, IL, Human Kinetics, 1991

1988, Hum Biol, 60, 709

10.1079/BJN19740060

1992, Eur Respir J, 5, 452, 10.1183/09031936.93.05040452

1993, J Appl Physiol, 21, 1

10.1007/BF00429077

10.1042/cs0400419

Orenstein DM. Assessment of exercise pulmonary function. In: Rowland TW, ed. Pediatric Laboratory Exercise Testing. Clinical Guidelines. Champaign, IL, Human Kinetics, 1993; pp. 141–163

2000, Med Sci Sports Exerc, 32, S442, 10.1097/00005768-200009001-00002

1998, Med Sci Sports Exerc, 30, 777, 10.1097/00005768-199805000-00021

1998, J Appl Physiol, 84, 963, 10.1152/jappl.1998.84.3.963

Welsman JR. Interpreting young peoples’ exercise performance: sizing up the problem. In: Armstrong N, Kirby BJ, Welsman JR, eds. Children and Exercise XIX. Promoting Health and Well-Being. London, E & FN Spon, 1997; pp. 191–203

1997, Ped Exerc Sci, 9, 295, 10.1123/pes.9.4.295

Hebestreit A, Kriemler S, Kieser S, et al. Effects of different conditioning programs on aerobic capacity in CF. Pediatr Pulmonol 2003; 36: Suppl. 25, 329

Klijn PH, Niuwenhuis M, van Stel H, et al. Validation of the Dutch pediatric cystic fibrosis quality of life questionnaire. In: Klijn PHC, ed. Physical fitness and quality of life in children with cystic fibrosis. Utrecht, PHC Klijn, 2003; pp. 41–57

10.1136/bjsm.35.2.118

10.2307/2986263

10.1016/S0002-9343(00)00472-1

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European Respiratory Journal

Tập 28 Số 4

734-739

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