Quorum sensing and environmental adaptation in Pseudomonas aeruginosa: a tale of regulatory networks and multifunctional signal molecules

Current Opinion in Microbiology - Tập 12 - Trang 182-191 - 2009
Paul Williams1, Miguel Cámara1
1School of Molecular Medical Sciences, Centre for Biomolecular Sciences, University of Nottingham, Nottingham NG7 2RD, United Kingdom

Tài liệu tham khảo

Joint, 2007, Bacterial conversations: talking, listening and eavesdropping. An introduction, Philos Trans R Soc Lond B Biol Sci, 362, 1115, 10.1098/rstb.2007.2038 Williams, 2007, Quorum sensing, communication and cross-kingdom signalling in the bacterial world, Microbiology, 153, 3923, 10.1099/mic.0.2007/012856-0 von Bodman, 2008, Cell-cell communication in bacteria: united we stand, J Bacteriol, 190, 4377, 10.1128/JB.00486-08 Mathee, 2008, Dynamics of Pseudomonas aeruginosa genome evolution, Proc Natl Acad U S A, 105, 3100, 10.1073/pnas.0711982105 Venturi, 2006, Regulation of quorum sensing in Pseudomonas, FEMS Microbiol Rev, 30, 274, 10.1111/j.1574-6976.2005.00012.x Latifi, 1996, A hierarchical quorum sensing cascade in Pseudomonas aeruginosa links the transcriptional activators LasR and RhIR (VsmR) to expression of the stationary-phase sigma factor RpoS, Mol Microbiol, 21, 1137, 10.1046/j.1365-2958.1996.00063.x Schuster, 2006, A network of networks: quorum-sensing gene regulation in Pseudomonas aeruginosa, Int J Med Microbiol, 296, 73, 10.1016/j.ijmm.2006.01.036 Yates, 2002, N-acylhomoserine Lactones undergo lactonolysis in a pH-, temperature-, and acyl chain length-dependent manner during growth of Yersinia pseudotuberculosis and Pseudomonas aeruginosa, Infect Immun, 70, 5635, 10.1128/IAI.70.10.5635-5646.2002 Rampioni, 2007, RsaL provides quorum sensing homeostasis and functions as a global regulator of gene expression in Pseudomonas aeruginosa, Mol Microbiol, 66, 1557, 10.1111/j.1365-2958.2007.06029.x Huang, 2006, Identification of QuiP, the product of Gene PA1032, as the second Acyl-Homoserine Lactone Acylase of Pseudomonas aeruginosa PAO1, Appl Environ Microbiol, 72, 1190, 10.1128/AEM.72.2.1190-1197.2006 Sio, 2006, Quorum quenching by an N-Acyl-Homoserine Lactone Acylase from Pseudomonas aeruginosa PAO1, Infect Immun, 74, 1673, 10.1128/IAI.74.3.1673-1682.2006 Schuster, 2004, Promoter specificity in Pseudomonas aeruginosa quorum sensing revealed by DNA binding of purified LasR, Proc. Natl Acad Sci U S A, 101, 15833, 10.1073/pnas.0407229101 Schuster, 2007, Early activation of quorum sensing in Pseudomonas aeruginosa reveals the architecture of a complex regulon, BMC Genomics, 8, 287, 10.1186/1471-2164-8-287 Smith, 2006, Genetic adaptation by Pseudomonas aeruginosa to the airways of cystic fibrosis patients, Proc Natl Acad Sci U S A, 103, 8487, 10.1073/pnas.0602138103 Winzer, 2000, The Pseudomonas aeruginosa lectins PA-IL and PA-IIL are controlled by quorum sensing and by RpoS, J Bacteriol, 182, 6401, 10.1128/JB.182.22.6401-6411.2000 Duan, 2007, Environmental regulation of Pseudomonas aeruginosa PAO1 Las and Rhl quorum-sensing systems, J Bacteriol, 189, 4827, 10.1128/JB.00043-07 Diggle, 2002, Advancing the quorum in Pseudomonas aeruginosa: MvaT and the regulation of N-acylhomoserine lactone production and virulence gene expression, J Bacteriol, 184, 2576, 10.1128/JB.184.10.2576-2586.2002 Lequette, 2006, A distinct QscR regulon in the Pseudomonas aeruginosa quorum-sensing circuit, J Bacteriol, 188, 3365, 10.1128/JB.188.9.3365-3370.2006 Ledgham, 2003, Interactions of the quorum sensing regulator QscR: interaction with itself and the other regulators of Pseudomonas aeruginosa LasR and RhlR, Mol Microbiol, 48, 199, 10.1046/j.1365-2958.2003.03423.x Juhas, 2004, Global regulation of quorum sensing and virulence by VqsR in Pseudomonas aeruginosa, Microbiology, 150, 831, 10.1099/mic.0.26906-0 Li, 2007, Regulation of the Pseudomonas aeruginosa quorum-sensing regulator VqsR, J Bacteriol, 189, 4367, 10.1128/JB.00007-07 Yarwood, 2005, Delays in Pseudomonas aeruginosa quorum-controlled gene expression are conditional, Proc Natl Acad Sci U S A, 102, 9008, 10.1073/pnas.0503728102 Pesci, 1999, Quinolone signaling in the cell-to-cell communication system of Pseudomonas aeruginosa, Proc Natl Acad Sci U S A, 96, 11229, 10.1073/pnas.96.20.11229 Diggle, 2003, The Pseudomonas aeruginosa quinolone signal molecule overcomes the cell density-dependency of the quorum sensing hierarchy, regulates rhl-dependent genes at the onset of stationary phase and can be produced in the absence of LasR, Mol Microbiol, 50, 29, 10.1046/j.1365-2958.2003.03672.x Xiao, 2006, MvfR, a key Pseudomonas aeruginosa pathogenicity LTTR-class regulatory protein, has dual ligands, Mol Microbiol, 62, 1689, 10.1111/j.1365-2958.2006.05462.x Déziel, 2004, Analysis of Pseudomonas aeruginosa 4-hydroxy-2-alkylquinolines (HAQs) reveals a role for 4-hydroxy-2-heptylquinoline in cell-to-cell communication, Proc Natl Acad Sci U S A, 101, 1339, 10.1073/pnas.0307694100 Gallagher, 2002, Functions required for extracellular quinolone signaling by Pseudomonas aeruginosa, J Bacteriol, 184, 6472, 10.1128/JB.184.23.6472-6480.2002 Xiao, 2006, Mutation analysis of the Pseudomonas aeruginosa mvfR and pqsABCDE gene promoters demonstrates complex quorum-sensing circuitry, Microbiology, 152, 1679, 10.1099/mic.0.28605-0 Diggle, 2007, The Pseudomonas aeruginosa 4-quinolone signal molecules HHQ and PQS play multifunctional roles in quorum sensing and iron entrapment, Chem Biol, 14, 87, 10.1016/j.chembiol.2006.11.014 Bredenbruch, 2006, The Pseudomonas aeruginosa quinolone signal (PQS) has an iron-chelating activity, Environ Microbiol, 8, 1318, 10.1111/j.1462-2920.2006.01025.x Toyofuku, 2008, Influence of the pseudomonas quinolone signal on denitrification in Pseudomonas aeruginosa, J Bacteriol, 190, 7947, 10.1128/JB.00968-08 Lamont, 2002, Siderophore-mediated signaling regulates virulence factor production in Pseudomonas aeruginosa, Proc Natl Acad Sci U S A, 99, 7072, 10.1073/pnas.092016999 Mashburn, 2005, Membrane vesicles traffic signals and facilitate group activities in a prokaryote, Nature, 437, 422, 10.1038/nature03925 Calfee, 2005, Solubility and bioactivity of the Pseudomonas quinolone signal are increased by a Pseudomonas aeruginosa-produced surfactant, Infect Immun, 73, 878, 10.1128/IAI.73.2.878-882.2005 Mashburn-Warren, 2008, Interaction of quorum signals with outer membrane lipids: insights into prokaryotic membrane vesicle formation, Mol Microbiol, 69, 491, 10.1111/j.1365-2958.2008.06302.x Allesen-Holm, 2006, A characterization of DNA release in Pseudomonas aeruginosa cultures and biofilms, Mol Microbiol, 59, 1114, 10.1111/j.1365-2958.2005.05008.x D’Argenio, 2002, Autolysis and autoaggregation in Pseudomonas aeruginosa colony morphology mutants, J Bacteriol, 184, 6481, 10.1128/JB.184.23.6481-6489.2002 DeWitte, 2001, Assessment of structural features of the pseudomonas siderophore pyochelin required for its ability to promote oxidant-mediated endothelial cell injury, Arch Biochem Biophys, 393, 236, 10.1006/abbi.2001.2517 Haussler, 2008, The pseudomonas quinolone signal (PQS) balances life and death in Pseudomonas aeruginosa populations, PLoS Pathogens, 4, e1000166, 10.1371/journal.ppat.1000166 Dietrich, 2006, The phenazine pyocyanin is a terminal signalling factor in the quorum sensing network of Pseudomonas aeruginosa, Mol Microbiol, 61, 1308, 10.1111/j.1365-2958.2006.05306.x Deziel, 2005, The contribution of MvfR to Pseudomonas aeruginosa pathogenesis and quorum sensing circuitry regulation: multiple quorum sensing-regulated genes are modulated without affecting lasRI, rhlRI or the production of N-acyl-L-homoserine lactones, Mol Microbiol, 55, 998, 10.1111/j.1365-2958.2004.04448.x Farrow, 2008, PqsE functions independently of PqsR-PQS and enhances the rhl quorum sensing system, J Bacteriol, 190, 7043, 10.1128/JB.00753-08 Qazi, 2006, N-acylhomoserine lactones antagonize virulence gene expression and quorum sensing in Staphylococcus aureus, Infect Immun, 74, 910, 10.1128/IAI.74.2.910-919.2006 Kaufmann, 2005, Revisiting quorum sensing: Discovery of additional chemical and biological functions for 3-oxo-N-acylhomoserine lactones, Proc Natl Acad Sci U S A, 102, 309, 10.1073/pnas.0408639102 Fletcher, 2007, A dual biosensor for 2-alkyl-4-quinolone quorum-sensing signal molecules, Environ Microbiol, 9, 2683, 10.1111/j.1462-2920.2007.01380.x Machan, 1992, 2-Heptyl-4-hydroxyquinoline N-oxide, an antistaphylococcal agent produced by Pseudomonas aeruginosa, J Antimicrob Chemother, 30, 615, 10.1093/jac/30.5.615 Hoffman, 2006, Selection for Staphylococcus aureus small-colony variants due to growth in the presence of Pseudomonas aeruginosa, Proc Natl Acad Sci U S A, 103, 19890, 10.1073/pnas.0606756104 Hogan, 2004, A Pseudomonas aeruginosa quorum-sensing molecule influences Candida albicans morphology, Mol Microbiol, 54, 1212, 10.1111/j.1365-2958.2004.04349.x Cugini, 2007, Farnesol, a common sesquiterpene, inhibits PQS production in Pseudomonas aeruginosa, Mol Microbiol, 65, 896, 10.1111/j.1365-2958.2007.05840.x Duan, 2003, Modulation of Pseudomonas aeruginosa gene expression by host microflora through interspecies communication, Mol Microbiol, 50, 1477, 10.1046/j.1365-2958.2003.03803.x Cooley, 2008, N-acylhomoserine lactone-mediated quorum sensing: a twist in the tail and a blow for host immunity, Chem Biol, 15, 1141, 10.1016/j.chembiol.2008.10.010 Jahoor, 2008, Peroxisome proliferator-activated receptors mediate host cell proinflammatory responses to Pseudomonas aeruginosa autoinducer, J Bacteriol, 190, 4408, 10.1128/JB.01444-07 Gardiner, 2001, Haemodynamic effects of the bacterial quorum sensing signal molecule, N-(3-oxododecanoyl)-L-homoserine lactone, in conscious, normal and endotoxaemic rats, Brit J Pharmacol, 133, 1047, 10.1038/sj.bjp.0704174 Vikstrom, 2009, The junctional integrity of epithelial cells is modulated by Pseudomonas aeruginosa quorum sensing molecule through phosphorylation-dependent mechanisms, Exp Cell Res, 315, 313, 10.1016/j.yexcr.2008.10.044 Stoltz, 2008, Drosophila are protected from Pseudomonas aeruginosa lethality by transgenic expression of paraoxonase-1, J Clin Invest, 118, 3123, 10.1172/JCI35147 Wu, 2005, Recognition of host immune activation by Pseudomonas aeruginosa, Science, 309, 774, 10.1126/science.1112422 Zaborina, 2007, Dynorphin activates quorum sensing quinolone signaling in Pseudomonas aeruginosa, PLoS Pathog, 3, e35, 10.1371/journal.ppat.0030035 Ni, 2009, Inhibitors and antagonists of bacterial quorum sensing, Med Res Rev, 29, 65, 10.1002/med.20145