Qa-2 expression levels is related with tumor-infiltrating lymphocytes profile during solid Ehrlich tumor development

Biomedicine & Pharmacotherapy - Tập 92 - Trang 750-756 - 2017
Istéfani Luciene da Silva1, Emerson Soares Veloso1, Ivy Nayra Nascimento Gonçalves1, Ariadne Duarte Braga2, Miriam Teresa Paz Lopes2, Geovanni Dantas Cassali1, Miguel Quintanilla3, Renata Toscano Simões4, Enio Ferreira1
1Department of General Pathology, Laboratory of Comparative Pathology, Biological Sciences Institute, Federal University of Minas Gerais, 486, 31270-901 Belo Horizonte, Minas Gerais, Brazil
2Department of Pharmacology, Laboratory of Antitumor Substances, Biological Sciences Institute, Federal University of Minas Gerais, 486, 31270-901, Belo Horizonte, Minas Gerais, Brazil
3Departament of Cancer Biology, Instituto de Investigaciones Biomédicas “Alberto Sols”, Consejo Superior de Investigaciones Científicas, Universidad Autónoma de Madrid, 4, 28029, Madrid, Spain
4Institute of Education and Research of Santa Casa of Belo Horizonte, 590, 30150-240, Belo Horizonte, Minas Gerais, Brazil

Tài liệu tham khảo

Delort, 2015, Leptin, adipocytes and breast cancer: focus on inflammation and anti-tumor immunity, Life Sci., 140, 37, 10.1016/j.lfs.2015.04.012 Engels, 2015, The prognostic and predictive value of Tregs and tumor immune subtypes in postmenopausal, hormone receptor-positive breast cancer patients treated with adjuvant endocrine therapy: a Dutch TEAM study analysis, Breast Cancer Res. Treat., 149, 587, 10.1007/s10549-015-3269-7 Romo-Gonzalez, 2015, The network of antigen-antibody reactions in adult women with breast cancer or benign breast pathology or without breast pathology, PLoS One, 10, e0119014, 10.1371/journal.pone.0119014 Agaugue, 2011, Role of HLA-G in tumor escape through expansion of myeloid-derived suppressor cells and cytokinic balance in favor of Th2 versus Th1/Th17, Blood, 117, 7021, 10.1182/blood-2010-07-294389 Matkowski, 2009, The prognostic role of tumor-infiltrating CD4 and CD8T lymphocytes in breast cancer, Anticancer Res., 29, 2445 Sato, 2005, Intraepithelial CD8+ tumor-infiltrating lymphocytes and a high CD8+/regulatory T cell ratio are associated with favorable prognosis in ovarian cancer, Proc. Natl. Acad. Sci. U. S. A., 102, 18538, 10.1073/pnas.0509182102 Mittal, 2014, New insights into cancer immunoediting and its three component phases–elimination, equilibrium and escape, Curr. Opin. Immunol., 27, 16, 10.1016/j.coi.2014.01.004 Dushyanthen, 2015, Relevance of tumor-infiltrating lymphocytes in breast cancer, BMC Med., 13, 202, 10.1186/s12916-015-0431-3 Wesolowski, 2014, Tumor infiltrating lymphocytes – the next step in assessing outcome and response to treatment in patients with breast cancer, J. Carcinog. Mutagen., 5 Cimino-Mathews, 2015, Immune targeting in breast cancer, Oncology (Williston Park), 29, 375 Tung, 2015, Tumor-infiltrating lymphocytes and response to platinum in triple-negative breast cancer, J. Clin. Oncol., 33, 969, 10.1200/JCO.2014.59.6031 Mao, 2014, The value of tumor infiltrating lymphocytes (TILs) for predicting response to neoadjuvant chemotherapy in breast cancer: a systematic review and meta-analysis, PLoS One, 9, e115103, 10.1371/journal.pone.0115103 Curigliano, 2013, Molecular pathways: human leukocyte antigen G (HLA-G), Clin. Cancer Res., 19, 5564, 10.1158/1078-0432.CCR-12-3697 Carosella, 2015, HLA-G: an immune checkpoint molecule, Adv. Immunol., 127, 33, 10.1016/bs.ai.2015.04.001 Richmond, 2008, Mouse xenograft models vs GEM models for human cancer therapeutics, Dis. Models Mech., 1, 78, 10.1242/dmm.000976 Cao, 1999, Search for a human homologue of the mouse Ped gene, Mol. Hum. Reprod., 5, 541, 10.1093/molehr/5.6.541 Lee, 2010, The role of Qa-2, the functional homolog of HLA-G, in a Behcet's disease-like mouse model induced by the herpes virus simplex, J. Inflamm. (Lond.), 7, 31, 10.1186/1476-9255-7-31 Comiskey, 2003, Evidence that HLA-G is the functional homolog of mouse Qa-2, the Ped gene product, Hum. Immunol., 64, 999, 10.1016/j.humimm.2003.08.352 Chiang, 2002, The nonclassical major histocompatibility complex molecule Qa-2 protects tumor cells from NK cell- and lymphokine-activated killer cell-mediated cytolysis, J. Immunol., 168, 2200, 10.4049/jimmunol.168.5.2200 Chiang, 2004, A nonclassical MHC class I molecule restricts CTL-mediated rejection of a syngeneic melanoma tumor, J. Immunol., 173, 4394, 10.4049/jimmunol.173.7.4394 Ungchusri, 2001, Widespread expression of the nonclassical class I Qa-2 antigens in hemopoietic and nonhemopoietic cells, Immunogenetics, 53, 455, 10.1007/s002510100347 Li, 2012, Qa-2 associated lipid rafts are indispensable in the final maturation of CD4(+)CD8(−) thymocytes, Immunol. Lett., 148, 163, 10.1016/j.imlet.2012.10.006 Hogarth, 1985, The distribution of the Qa-2 alloantigen on functional T lymphocytes, J. Immunol., 135, 1632, 10.4049/jimmunol.135.3.1632 De Fazio, 2007, Activation of T cells by cross-linking Qa-2, the ped gene product, requires Fyn, Am. J. Reprod. Immunol., 58, 315, 10.1111/j.1600-0897.2007.00503.x Hahn, 1989, Anti-Qa-2-induced T cell activation. The parameters of activation, the definition of mitogenic and nonmitogenic antibodies, and the differential effects on CD4+ vs CD8+ T cells, J. Immunol., 143, 407, 10.4049/jimmunol.143.2.407 Cook, 1992, Characterization of T cell proliferative responses induced by anti-Qa-2 monoclonal antibodies, Cell. Immunol., 144, 367, 10.1016/0008-8749(92)90252-K He, 2001, Promiscuous antigen presentation by the nonclassical MHC Ib Qa-2 is enabled by a shallow, hydrophobic groove and self-stabilized peptide conformation, Structure, 9, 1213, 10.1016/S0969-2126(01)00689-X Kabel, 2015, Effect of metformin and adriamycin on transplantable tumor model, Tissue Cell, 47, 498, 10.1016/j.tice.2015.07.003 Ferreira, 2007, Ehrlich tumor as model to study artificial hyperthyroidism influence on breast cancer, Pathol. Res. Pract., 203, 39, 10.1016/j.prp.2006.09.005 Dong, 2010, Human leukocyte antigen-G (HLA-G) expression in cervical lesions: association with cancer progression, HPV 16/18 infection, and host immune response, Reprod. Sci., 17, 718, 10.1177/1933719110369183 Loumagne, 2014, In vivo evidence that secretion of HLA-G by immunogenic tumor cells allows their evasion from immunosurveillance, Int. J. Cancer, 135, 2107, 10.1002/ijc.28845 Liu, 2010, Tumor initiation via loss of cell contact inhibition versus Ras mutation: do all roads lead to EMT?, ABBV Cell Cycle, 9, 897, 10.4161/cc.9.5.10933 Park, 2004, Soluble HLA-G generated by proteolytic shedding inhibits NK-mediated cell lysis, Biochem. Biophys. Res. Commun., 313, 606, 10.1016/j.bbrc.2003.11.153 Rizzo, 2013, Matrix metalloproteinase-2 (MMP-2) generates soluble HLA-G1 by cell surface proteolytic shedding, Mol. Cell. Biochem., 381, 243, 10.1007/s11010-013-1708-5 Marshall, 2016, Emerging roles of T helper 17 and regulatory T cells in lung cancer progression and metastasis, Mol. Cancer, 15, 67, 10.1186/s12943-016-0551-1