The Protein Structure Initiative Structural Biology Knowledgebase Technology Portal: a structural biology web resource
Tóm tắt
The Technology Portal of the Protein Structure Initiative Structural Biology Knowledgebase (PSI SBKB;
http://technology.sbkb.org/portal/
) is a web resource providing information about methods and tools that can be used to relieve bottlenecks in many areas of protein production and structural biology research. Several useful features are available on the web site, including multiple ways to search the database of over 250 technological advances, a link to videos of methods on YouTube, and access to a technology forum where scientists can connect, ask questions, get news, and develop collaborations. The Technology Portal is a component of the PSI SBKB (
http://sbkb.org
), which presents integrated genomic, structural, and functional information for all protein sequence targets selected by the Protein Structure Initiative. Created in collaboration with the Nature Publishing Group, the SBKB offers an array of resources for structural biologists, such as a research library, editorials about new research advances, a featured biological system each month, and a functional sleuth for searching protein structures of unknown function. An overview of the various features and examples of user searches highlight the information, tools, and avenues for scientific interaction available through the Technology Portal.
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PSI SBKB Technology Portal (2009) High-throughput protein expression. Available from: http://technology.sbkb.org/portal/page/1/
PSI SBKB Technology Portal (2009) LIC (Ligation-independent cloning) vectors. Available from: http://technology.sbkb.org/portal/page/36/
PSI SBKB Technology Portal (2009) New vectors for co-expression of proteins. Available from: http://technology.sbkb.org/portal/page/52/
PSI SBKB Technology Portal (2009) Customized expression vector platform. Available from: http://technology.sbkb.org/portal/page/98/
PSI SBKB Technology Portal (2009) Structural genomics methods applied to production of TEV protease. Available from: http://technology.sbkb.org/portal/page/107/
PSI SBKB Technology Portal (2009) A combined approach to improving large-scale production of tobacco etch virus protease. Available from: http://technology.sbkb.org/portal/page/164/
PSI SBKB Technology Portal (2009) One-plasmid tunable co-expression for mycobacterial protein-protein interaction studies. Available from: http://technology.sbkb.org/portal/page/167/