Cytotoxic activity of medicinal plants of the Kakamega County (Kenya) against drug-sensitive and multidrug-resistant cancer cells

Abdelfatah, 2015, Cytotoxicity of the indole alkaloid reserpine from Rauwolfia serpentina against drug-resistant tumor cells, Phytomedicine, 22, 308, 10.1016/j.phymed.2015.01.002 Amiri-Kordestani, 2012, Targeting MDR in breast and lung cancer: discriminating its potential importance from the failure of drug resistance reversal studies, Drug Resist. Updates, 15, 50, 10.1016/j.drup.2012.02.002 Binkhathlan, 2013, P-glycoprotein inhibition as a therapeutic approach for overcoming multidrug resistance in cancer: current status and future perspectives, Curr. Cancer Drug Targets, 13, 326, 10.2174/15680096113139990076 Chen, 2016, Mammalian drug efflux transporters of the ATP binding cassette (ABC) family in multidrug resistance: a review of the past decade, Cancer Lett., 370, 153, 10.1016/j.canlet.2015.10.010 Cheraghi, 2016, Potent anti-angiogenic and cytotoxic effect of conferone on human colorectal adenocarcinoma HT-29 cells, Phytomedicine, 23, 398, 10.1016/j.phymed.2016.01.015 CITES, 2003. Review of Significant Trade East African Aloes, 〈http://www.cites.org/eng/com/pc/14/E-PC14-09-02-02-A4.pdf〉. Doyle, 1998, A multidrug resistance transporter from human MCF-7 breast cancer cells, Proc. Natl. Acad. Sci. USA, 95, 15665, 10.1073/pnas.95.26.15665 Durmaz, 2016, Liver cancer cells are sensitive to Lanatoside C induced cell death independent of their PTEN status, Phytomedicine, 23, 42, 10.1016/j.phymed.2015.11.012 Efferth, 2001, The human ATP-binding cassette transporter genes: from the bench to the bedside, Curr. Mol. Med., 1, 45, 10.2174/1566524013364194 2015 Efferth, 2000, Impact of viral oncogenesis on responses to anti-cancer drugs and irradiation, Crit. Rev. Oncog., 11, 165 Efferth, 2005, Pharmacogenetics for individualized cancer chemotherapy, Pharmacol. Ther., 107, 155, 10.1016/j.pharmthera.2005.02.005 Efferth, 2003, Molecular modes of action of artesunate in tumor cell lines, Mol. Pharmacol., 64, 382, 10.1124/mol.64.2.382 Efferth, 2003, Molecular modes of action of cephalotaxine and homoharringtonine from the coniferous tree Cephalotaxus hainanensis in human tumor cell lines, Naunyn Schmiede. Arch. Pharmacol., 367, 56, 10.1007/s00210-002-0632-0 Efferth, 2004, Enhancement of cytotoxicity of artemisinins toward cancer cells by ferrous iron, Free Radic. Biol. Med., 37, 998, 10.1016/j.freeradbiomed.2004.06.023 Efferth, 2008, Prediction of broad spectrum resistance of tumors towards anticancer drugs, Clin. Cancer Res., 14, 2405, 10.1158/1078-0432.CCR-07-4525 Efferth, 2016, Biopiracy of natural products and good bioprospecting practice, Phytomedicine, 23, 166, 10.1016/j.phymed.2015.12.006 Efferth, 2017, Integration of phytochemicals and phytotherapy into cancer precision medicine, Oncotarget, 8, 50284, 10.18632/oncotarget.17466 Efferth, 2003, Molecular modes of action of artesunate in tumor cell lines, Mol. Pharmacol., 64, 382, 10.1124/mol.64.2.382 el-Deiry, 1997, Role of oncogenes in resistance and killing by cancer therapeutic agents, Curr. Opin. Oncol., 9, 79, 10.1097/00001622-199701000-00013 Fadeyi, 2013, In vitro anticancer screening of 24 locally used Nigerian medicinal plants, BMC Complement. Altern. Med., 13, 79, 10.1186/1472-6882-13-79 Frączek, 2016, An outline of main factors of drug resistance influencing cancer therapy, J. Chemother., 28, 457, 10.1080/1120009X.2016.1218158 Gatouillat, 2015, Medicarpin and millepurpan, two flavonoids isolated from Medicago sativa, induce apoptosis and overcome multidrug resistance in leukemia P388 cells, Phytomedicine, 22, 1186, 10.1016/j.phymed.2015.09.005 Gillet, 2007, Chemotherapy-induced resistance by ATP-binding cassette transporter genes, Biochim. Biophys. Acta, 1775, 237 Gottesman, 2006, The molecular basis of multidrug resistance in cancer: the early years of P-glycoprotein research, FEBS Lett., 580, 998, 10.1016/j.febslet.2005.12.060 Guo, 2016, Sinapine reverses multi-drug resistance in MCF-7/dox cancer cells by downregulating FGFR4/FRS2α-ERK1/2 pathway-mediated NF-κB activation, Phytomedicine, 23, 267, 10.1016/j.phymed.2015.12.017 Hientz, 2017, The role of p53 in cancer drug resistance and targeted chemotherapy, Oncotarget, 8, 8921, 10.18632/oncotarget.13475 Iwalewa, 2008, Anti-protozoan activities of Harungana madagascariensis stem bark extract on trichomonads and malaria, J. Ethnopharmacol., 117, 507, 10.1016/j.jep.2008.02.019 Jemal, 2008, Cancer statistics, 2008, CA Cancer J. Clin., 58, 71, 10.3322/CA.2007.0010 Juengel, 2017, Sulforaphane as an adjunctive to everolimus counteracts everolimus resistance in renal cancer cell lines, Phytomedicine, 27, 1, 10.1016/j.phymed.2017.01.016 Kouam, 2006, Alpha-glucosidase inhibitory anthranols, kenganthranols A-C, from the stem bark of Harungana madagascariensis, J. Nat. Prod., 69, 229, 10.1021/np050407n Kouam, 2005, Prenylated anthronoid antioxidants from the stem bark of Harungana madagascariensis, Phytochemistry, 66, 1174, 10.1016/j.phytochem.2005.03.022 Kouam, 2007, Antimicrobial prenylated anthracene derivatives from the leaves of Harungana madagascariensis, J. Nat. Prod., 70, 600, 10.1021/np060556l Kuete, 2015, African flora has the potential to fight multidrug resistance of cancer, Biomed. Res. Int., 2015, 914813, 10.1155/2015/914813 Kuete, 2015, Cytotoxicity of three naturally occurring flavonoid derived compounds (artocarpesin, cycloartocarpesin and isobavachalcone) towards multi-factorial drug-resistant cancer cells, Phytomedicine, 22, 1096, 10.1016/j.phymed.2015.07.006 Kuete, 2016, Cytotoxicity of seven naturally occurring phenolic compounds towards multi-factorial drug-resistant cancer cells, Phytomedicine, 23, 856, 10.1016/j.phymed.2016.04.007 Kuete, 2016, Cytotoxicity of seven naturally occurring phenolic compounds towards multi-factorial drug-resistant cancer cells, Phytomedicine, 23, 856, 10.1016/j.phymed.2016.04.007 Kuete, 2016, Cytotoxicity of 15 Cameroonian medicinal plants against drug sensitive and multi-drug resistant cancer cells, J. Ethnopharmacol., 186, 196, 10.1016/j.jep.2016.04.001 Kuete, 2017, Cytotoxicity and mode of action of a naturally occurring naphthoquinone, 2-acetyl-7-methoxynaphtho[2,3-b]furan-4,9-quinone towards multi-factorial drug-resistant cancer cells, Phytomedicine, 33, 62, 10.1016/j.phymed.2017.07.010 MacMicking, 1997, Nitric oxide and macrophage function, Annu. Rev. Immunol., 15, 323, 10.1146/annurev.immunol.15.1.323 Mukherjee, 2009, EGFRvIII and DNA double-strand break repair: a molecular mechanism for radioresistance in glioblastoma, Cancer Res., 69, 4252, 10.1158/0008-5472.CAN-08-4853 Nagane, 1996, A common mutant epidermal growth factor receptor confers enhanced tumorigenicity on human glioblastoma cells by increasing proliferation and reducing apoptosis, Cancer Res., 56, 5079 Nagane, 1998, Drug resistance of human glioblastoma cells conferred by a tumor-specific mutant epidermal growth factor receptor through modulation of Bcl-XL and caspase-3-like proteases, Proc. Natl. Acad. Sci. USA, 95, 5724, 10.1073/pnas.95.10.5724 Nwodo, 1989, Antibiotic and anti-inflammatory analgesic activities of Harungana madagascariensis stem bark, Int. J. Crude Drug Res., 27, 137, 10.3109/13880208909053953 O'Brien, 2000, Investigation of the Alamar Blue (resazurin) fluorescent dye for the assessment of mammalian cell cytotoxicity, Eur. J. Biochem., 267, 5421, 10.1046/j.1432-1327.2000.01606.x Ochwang'i, 2014, Medicinal plants used in treatment and management of cancer in Kakamega County, Kenya, J. Ethnopharmacol., 151, 1040, 10.1016/j.jep.2013.11.051 Ooko, 2016, Modulation of P-glycoprotein activity by novel synthetic curcumin derivatives in sensitive and multidrug-resistant T-cell acute lymphoblastic leukemia cell lines, Toxicol. Appl. Pharmacol., 305, 216, 10.1016/j.taap.2016.06.002 Paillas, 2012, MAPK14/p38α confers irinotecan resistance to TP53-defective cells by inducing survival autophagy, Autophagy, 8, 1098, 10.4161/auto.20268 Pluchino, 2012, Collateral sensitivity as a strategy against cancer multidrug resistance, Drug Resist. Updates, 15, 98, 10.1016/j.drup.2012.03.002 Reis, 2016, Jatrophane diterpenes and cancer multidrug resistance - ABCB1 efflux modulation and selective cell death induction, Phytomedicine, 23, 968, 10.1016/j.phymed.2016.05.007 Saeed, 2013, Collateral sensitivity in drug-resistant tumor cells, 187 Schmidt, 2016, Tumor heterogeneity, single-cell sequencing, and drug resistance, Pharm. (Basel), 9 Seo, 2015, Cytotoxicity of natural products and derivatives toward MCF-7 cell monolayers and cancer stem-like mammospheres, Phytomedicine, 22, 438, 10.1016/j.phymed.2015.01.012 Shrestha, 2016, Sageone, a diterpene from Rosmarinus officinalis, synergizes with cisplatin cytotoxicity in SNU-1 human gastric cancer cells, Phytomedicine, 23, 1671, 10.1016/j.phymed.2016.09.008 Suffness, 1990, Assays related to cancer drug discovery, 6 Tanaka, 2011, Oncogenic EGFR signaling activates an mTORC2-NF-κB pathway that promotes chemotherapy resistance, Cancer Discov., 1, 524, 10.1158/2159-8290.CD-11-0124 Tarasiuk, 2002, Anthrapyridones, a novel group of antitumour non-cross resistant anthraquinone analogues. Synthesis and molecular basis of the cytotoxic activity towards K562/DOX cells, Br. J. Pharmacol., 135, 1513, 10.1038/sj.bjp.0704611 Teng, 2016, beta-carotene reverses multidrug resistant cancer cells by selectively modulating human P-glycoprotein function, Phytomedicine, 23, 316, 10.1016/j.phymed.2016.01.008 Tkaczyk-Gobis, 2001, Transport of new non-cross-resistant antitumor compounds of the benzoperimidine family in multidrug resistant cells, Eur. J. Pharmacol., 413, 131, 10.1016/S0014-2999(01)00728-2 Umsumarng, 2017, Modulation of P-glycoprotein by Stemona alkaloids in human multidrug resistance leukemic cells and structural relationships, Phytomedicine, 34, 182, 10.1016/j.phymed.2017.08.004 Volm, 2015, Prediction of cancer drug resistance and implications for personalized medicine, Front. Oncol., 5, 282, 10.3389/fonc.2015.00282 Wang, 2003, Inhaled nitric oxide in 2003: a review of its mechanisms of action, Can. J. Anaesthesiol., 50, 839, 10.1007/BF03019384 Wang, 2007, Mechanisms of acquired chemoresistance to 5-fluorouracil and tomudex: thymidylate synthase dependent and independent networks, Cancer Chemother. Pharmacol., 59, 839, 10.1007/s00280-006-0384-5 Wu, 2015, Miltirone induces G2/M cell cycle arrest and apoptosis in CCRF-CEM acute lymphoblastic leukemia cells, J. Nat. Prod., 78, 1339, 10.1021/acs.jnatprod.5b00158