Neuropsychological function in children following admission to paediatric intensive care: a pilot investigation

Sarah Elison1, Dan Shears2, Simon Nadel3, Barbara J. Sahakian4, M. Elena Garralda2
1Imperial College London
2Academic Unit of Child and Adolescent Psychiatry, Imperial College London, London, UK
3Dept of Pediatric Intensive Care, St Mary’s Hospital, Praed Street, W2 1NY, London, UK
4Department of Psychiatry, University of Cambridge, School of Clinical Medicine, Addenbrooke's Hospital, Cambridge, UK

Tóm tắt

Từ khóa


Tài liệu tham khảo

Rees G, Gledhill J, Garralda E, Nadel S (2004) Psychiatric outcome following pediatric intensive care unit (PICU) admission: a cohort study. Intensive Care Med 30:1607–1614

Shears D, Nadel S, Gledhill J, Garralda ME (2005) Short-term psychiatric adjustment of children and their parents following meningococcal disease. Pediatr Crit Care Med 6:39–43

Diaz-Caneja A, Gledhill J, Weaver T, Nadel S, Garralda E (2005) A child's admission to hospital: a qualitative study examining the experiences of parents. Intensive Care Med 31:1248–1254

Broadhurst C, Wilson K (2001) Immunology of delirium: new opporunities for treatment and research. B J Psychiatry 179:288–289

Pathan N, Faust SN, Levin M (2003) Pathophysiology of menningococcal meningitis and septicaemia. Arch Dis Child 88:601–607

Turnbull GJ (2003) The biology of PTSD. Psychiatry 2:5–9

Watson S, Young AH (2003) HPA axis function in mood disorders. Psychiatry 2:51–54

Jones C, Griffiths RD, Slater T, Benjamin KS, Wilson S (2006) Significant cognitive dysfunction in non-delirious patients identified during and persisting following critical illness. Intensive Care Med 32:923–926

Knoester H, Grootenhuis MA, Bos AP (2007) Outcome of paediatric intensive care survivors. Eur J Pediatr 166:1119–1128

Pearson GA, Stickley J, Shann F (2001) Calibration of the Paediatric Index of Mortality in UK paediatric intensive care units. Arch Dis Child 84:125–128

Luciana M (2003) Practitioner review: computerized assessment of neuropsychological function in children: cliical and research applications of the Cambridge Neuropsychological Testing Automated Battery (CANTAB). J Child Psychol Psychiatry 44:649–663

Cohen MJ (1997) Manual for the Children's Memory Scale. Psychological Corporation

Wechsler D (1999) Manual for the WASI. Psychological Corporation

Goodman R, Ford T, Simmons H, Gatward R, Meltzer H (2000) Using the Strengths and Difficulties Questionnaire (SDQ) to screen for child psychiatric disorders in a community sample. Br J Psychiatry 177:534–539

Perrin S, Smith P, Yule W (2000) Practitioner review: the assessment and treatment of post-traumatic stress disorder in children and adolescents. J Child Psychol Psychiatry 41:277–289

Owen AM, Doyon J, Petrides M, Evans AC (1996) Planning and spatial working memory: a positron emission study in humans. Eur J Neurosci 8:353–364

Williams D, Stott CM, Goodyer IM, Sahakian BJ (2000) Specific language impairment with or without hyperactivity: neuropsychological evidence for frontal dysfunction. Dev Med Child Neurol 42:368–375

Vythilingham M, Luckenbaugh DA, Lam T, Morgan CA, Lipschitz D, Charney DS, Bremner JD, Southwick SM (2005) Smaller head of the hippocampus in Gulf War related postraumatic stress disorder. Psychiatr Res Neuroimaging 139:89–99

Curtis WJ, Lindeke LL, Georgieff MK, Nelson CA (2002) Neurobehavioural functioning in neonatal intensive care unit graduates in late childhood and early adolescence. Brain 125:1646–1659

Schieveld JNM, Leroy PLJM, van Os J, Nicolai J, Vos GD, Leentjens AFG (2007) Pediatric delirium in critical illness: phenomenology, clinical correlates and treatment response in 40 cases in the pediatric intensive care unit. Intensive Care Med 33:1033–1040

Pandharipande P, Cotton BA, Shintani A, Thompson J, Costabile S, Pun BT, Dittus R, Ely EW (2007) Motoric subtypes of delirium in mechanically ventilated surgical and trauma intensive care unit patients. Intensive Care Med 33:1726–1731

Mehta MA, Goodyer IM, Sahakian BJ (2004) Methylphenidate improves working memory and set-shifting in ADHD: relationships to baseline memory capacity. J Child Psychol Psychiatry 43:293–305

Barichello T, Martins MR, Reinke A, Feier G, Ritter C, Quevedo J, Dal-Pizzol F (2005) Cognitive impairment in sepsis survivors from cecal ligation and perforation. Crit Care Med 33:221–223

Schmidt H, Heinmann B, Djukic M (2005) Neuropsychological sequelae of bacterial and viral meningitis. Brain 129:333–345

Owen AM, Sahakian BJ, Semple J, Polkey CE, Robbins TW (1995) Visual-spatial short-term recognition memory and learning after temporal lobe excisions, frotal lobe excisions or amyygdalo-hippocampectomy in man. Neuropsychologia 33:1–24