Expert recommendations on blood purification treatment protocol for patients with severe COVID‐19☆

Chronic Diseases and Translational Medicine - Tập 6 - Trang 106-114 - 2020
Xiang-Hong Yang1, Ren-Hua Sun1, Ming-Yan Zhao2, Er-Zhen Chen3, Jiao Liu4, Hong-Liang Wang5, Rong-Li Yang6, De-Chang Chen3
1Department of Critical Care Medicine, Zhejiang Provincial People's Hospital, Hangzhou, Zhejiang 310014, China
2Department of Critical Care Medicine, The First Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150001, China
3Department of Critical Care Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China
4Department of Critical Care Medicine, Ruijin Hospital North, Shanghai Jiao Tong University School of Medicine, Shanghai 201800, China
5Department of Critical Care Medicine, The Second Affiliated Hospital of Harbin Medical University, Harbin, Heilongjiang 150001, China
6Department of Critical Care Medicine, Dalian Municipal Central Hospital, Dalian, Liaoning 116033, China

Tóm tắt

AbstractCoronavirus disease (COVID‐19) was first diagnosed in Wuhan in December 2019. The World Health Organization defined the subsequent outbreak of COVID‐19 worldwide as a public health emergency of international concern. Epidemiological data indicate that at least 20% of COVID‐19 patients have severe disease. In addition to impairment of the respiratory system, acute kidney injury (AKI) is a major complication. Immune damage mediated by cytokine storms and concomitant AKI is a key factor for poor prognosis. Based on previous experience of blood purification for patients with severe acute respiratory syndrome and Middle East respiratory syndrome combined with clinical front‐line practice, we developed a blood purification protocol for patients with severe COVID‐19. This protocol is divided into four major steps. The first step is to assess whether patients with severe COVID‐19 require blood purification. The second step is to prescribe a blood purification treatment for patients with COVID‐19. The third step is to monitor and adjust parameters of blood purification. The fourth step is to evaluate the timing of discontinuation of blood purification. It is expected that blood purification will play a key role in effectively reducing the mortality of patients with severe COVID‐19 through the standardized implementation of the present protocol.

Tài liệu tham khảo

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Chronic Diseases and Translational Medicine

Tập 6

106-114

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