Ainsworth, 1981, Effects of capsaicin applied locally to adult peripheral nerve. II. Anatomy and enzyme and peptide chemistry of peripheral nerve and spinal cord, Pain, 11, 379, 10.1016/0304-3959(81)90637-0
Bao, 2002, Peripheral axotomy induces only very limited sprouting of coarse myelinated afferents into inner lamina II of rat spinal cord, Eur J Neurosci, 16, 175, 10.1046/j.1460-9568.2002.02080.x
Brown, 1981
Caterina, 1997, The capsaicin receptor: a heat-activated ion channel in the pain pathway, Nature, 389, 816, 10.1038/39807
Chung, 1985, Effects of capsaicin applied to a peripheral nerve on the responses of primate spinothalamic tract cells, Brain Res, 329, 27, 10.1016/0006-8993(85)90509-8
Crain, 1998, Modulation of opioid analgesia, tolerance and dependence by Gs-coupled, GM1 ganglioside-regulated opioid receptor functions, Trends Pharmacol Sci, 19, 358, 10.1016/S0165-6147(98)01241-3
Cuatrecasas, 1973, Gangliosides and membrane receptors for cholera toxin, Biochemistry, 12, 3558, 10.1021/bi00742a032
Dilley, 2013, Disruption of fast axonal transport in the rat induces behavioral changes consistent with neuropathic pain, J Pain, 14, 1437, 10.1016/j.jpain.2013.07.005
Duchemin, 2008, GM1-induced activation of phosphatidylinositol 3-kinase: involvement of Trk receptors, J Neurochem, 104, 1466, 10.1111/j.1471-4159.2007.05088.x
Eidels, 1983, Membrane receptors for bacterial toxins, Microbiol Rev, 47, 596, 10.1128/MMBR.47.4.596-620.1983
Fazen, 2008, The pathophysiology of neuropathic pain: a review of current research and hypotheses, Neurosurg Q, 17, 245, 10.1097/WNQ.0b013e3181506c70
Fitzgerald, 1982, The time course and specificity of the changes in the behavioural and dorsal horn cell responses to noxious stimuli following peripheral nerve capsaicin treatment in the rat, Neuroscience, 7, 2051, 10.1016/0306-4522(82)90119-1
Gamse, 1982, Capsaicin applied to peripheral nerve inhibits axoplasmic transport of substance P and somatostatin, Brain Res, 239, 447, 10.1016/0006-8993(82)90521-2
Gibson, 1982, Local application of capsaicin to one sciatic nerve of the adult rat induces a marked depletion in the peptide content of the lumbar dorsal horn, Neuroscience, 7, 3153, 10.1016/0306-4522(82)90237-8
Gu, 1992, Electron microscopical demonstration of horseradish peroxidase by use of tetramethylbenzidine as chromogen and sodium tungstate as stabilizer (TMB-ST method): a tracing method with high sensitivity and well preserved ultrastructural tissue, J Neurosci Methods, 42, 1, 10.1016/0165-0270(92)90129-2
Holzer, 1991, Capsaicin: cellular targets, mechanisms of action, and selectivity for thin sensory neurons, Pharmacol Rev, 43, 143
Hughes, 2004, Peripheral axotomy induces depletion of the vesicular glutamate transporter VGLUT1 in central terminals of myelinated afferent fibres in the rat spinal cord, Brain Res, 1017, 69, 10.1016/j.brainres.2004.05.054
Hughes, 2003, Lack of evidence for sprouting of Abeta afferents into the superficial laminas of the spinal cord dorsal horn after nerve section, J Neurosci, 23, 9491, 10.1523/JNEUROSCI.23-29-09491.2003
Inomata, 1979, Ultracytochemical localization of thiamine monophosphatase activity in the substantia gelatinosa of the rat spinal cord, Acta Histochem Cytochem, 12, 337, 10.1267/ahc.12.337
Jancsó, 1992, Pathobiological reactions of C-fibre primary sensory neurones to peripheral nerve injury, Exp Physiol, 77, 405, 10.1113/expphysiol.1992.sp003603
Jancsó, 1994, Capsaicin sensitivity of primary sensory neurones and its regulation, 71
Jancsó, 1990, Transganglionic degeneration of capsaicin-sensitive C-fiber primary afferent terminals, Neuroscience, 39, 501, 10.1016/0306-4522(90)90286-D
Jancsó, 1987, Possible use of capsaicin in pain therapy, Clin J Pain, 3, 123, 10.1097/00002508-198703000-00001
Jancsó, 2004, Transganglionic transport of choleragenoid by injured C fibers to the substantia gelatinosa: relevance to neuropathic pain and hyperalgesia, 143
Jancsó, 2015, The foundation of sensory pharmacology: Nicholas (Miklós) Jancsó and the Szeged contribution, Temperature, 2, 152, 10.1080/23328940.2015.1045683
Jancsó, 1983, Effects of capsaicin applied perineurally to the vagus nerve on cardiovascular and respiratory functions in the cat, J Physiol, 341, 359, 10.1113/jphysiol.1983.sp014810
Jancsó, 1980, Direct evidence for an axonal site of action of capsaicin, Naunyn-Schmiedebergs Arch Pharmacol, 313, 91, 10.1007/BF00505809
Jancsó, 1985, Morphological effects of capsaicin and its analogues in newborn and adult mammals, 35
Jancsó, 1987, Neurotoxic effect of capsaicin in mammals, Acta Physiol Hung, 69, 295
Jancsó, 1987, A new approach to selective regional analgesia, 59
Jancsó, 2002, Peripheral nerve lesion-induced uptake and transport of choleragenoid by capsaicin-sensitive c-fibre spinal ganglion neurons, Acta Biol Hung, 53, 77, 10.1556/ABiol.53.2002.1-2.9
Jancsó, 2004, Selective C-fiber deafferentation of the spinal dorsal horn prevents lesion-induced transganglionic transport of choleragenoid to the substantia gelatinosa in the rat, Neurosci Lett, 361, 204, 10.1016/j.neulet.2003.12.063
Jancsó, 2008, Activation of the transient receptor potential vanilloid-1 (TRPV1) channel opens the gate for pain relief, Br J Pharmacol, 155, 1139, 10.1038/bjp.2008.375
Jancsó, 2011, The capsaicin paradox: pain relief by an analgesic agent, Antiinflamm Antiallergy Agents Med Chem, 10, 52, 10.2174/187152311795325514
Kissin, 2008, Vanilloid-induced conduction analgesia: selective, dose-dependent, long-lasting, with a low level of potential neurotoxicity, Anesth Analg, 107, 271, 10.1213/ane.0b013e318162cfa3
Kissin, 2002, Selective and long-lasting neural blockade with resiniferatoxin prevents inflammatory pain hypersensitivity, Anesth Analg, 94, 1253, 10.1097/00000539-200205000-00038
Knotkova, 2008, Capsaicin (TRPV1 Agonist) therapy for pain relief: farewell or revival?, Clin J Pain, 24, 142, 10.1097/AJP.0b013e318158ed9e
Koerber, 1994, Central sprouting and functional plasticity of regenerated primary afferents, J Neurosci, 14, 3655, 10.1523/JNEUROSCI.14-06-03655.1994
Kohama, 2000, Synaptic reorganization in the substantia gelatinosa after peripheral nerve neuroma formation: aberrant innervation of lamina II neurons by Abeta afferents, J Neurosci, 20, 1538, 10.1523/JNEUROSCI.20-04-01538.2000
Kuner, 2010, Central mechanisms of pathological pain, Nat Med, 16, 1258, 10.1038/nm.2231
LaMotte, 1991, Central projections of the sciatic, saphenous, median, and ulnar nerves of the rat demonstrated by transganglionic transport of choleragenoid-HRP (B-HRP) and wheat germ agglutinin-HRP (WGA-HRP), J Comp Neurol, 311, 546, 10.1002/cne.903110409
Ledeen, 2015, The multi-tasked life of GM1 ganglioside, a true factotum of nature, Trends Biochem Sci, 40, 407, 10.1016/j.tibs.2015.04.005
Leon, 1984, Dorsal root ganglia and nerve growth factor: a model for understanding the mechanism of GM1 effects on neuronal repair, J Neurosci Res, 12, 277, 10.1002/jnr.490120215
Liu, 2006, TRPV1, but not P2X, requires cholesterol for its function and membrane expression in rat nociceptors, Eur J Neurosci, 24, 1, 10.1111/j.1460-9568.2006.04889.x
Lynn, 1984, Axonal recovery and development of a long-lasting peripheral block in C-fibre polymodal nociceptors after local nerve treatment with capsaicin in the rat, J Physiol, 350, 34
Maggi, 1989, Topical versus systemic capsaicin desensitization: specific and unspecific effects as indicated by modification or reflex micturition in rats, Neuroscience, 31, 745, 10.1016/0306-4522(89)90438-7
Maiya, 2014, Peripheral systems: neuropathy, Handb Clin Neurol, 125, 513, 10.1016/B978-0-444-62619-6.00029-X
Mannion, 1996, Collateral sprouting of uninjured primary afferent A-fibers into the superficial dorsal horn of the adult rat spinal cord after topical capsaicin treatment to the sciatic nerve, J Neurosci, 16, 5189, 10.1523/JNEUROSCI.16-16-05189.1996
Mesulam, 1978, Tetramethyl benzidine for horseradish peroxidase neurohistochemistry: a non-carcinogenic blue reaction product with superior sensitivity for visualizing neural afferents and efferents, J Histochem Cytochem, 26, 106, 10.1177/26.2.24068
Michael, 1999, Differential expression of the mRNA for the vanilloid receptor subtype 1 in cells of the adult rat dorsal root and nodose ganglia and its downregulation by axotomy, J Neurosci, 19, 1844, 10.1523/JNEUROSCI.19-05-01844.1999
Mutoh, 1995, Ganglioside GM1 binds to the Trk protein and regulates receptor function, Proc Natl Acad Sci U S A, 92, 5087, 10.1073/pnas.92.11.5087
Nagy, 2004, The role of the vanilloid (capsaicin) receptor (TRPV1) in physiology and pathology, Eur J Pharmacol, 500, 351, 10.1016/j.ejphar.2004.07.037
Nishio, 2004, Overexpressed GM1 suppresses nerve growth factor (NGF) signals by modulating the intracellular localization of NGF receptors and membrane fluidity in PC12 cells, J Biol Chem, 279, 33368, 10.1074/jbc.M403816200
Petsche, 1983, The effect of capsaicin application to a peripheral nerve on impulse conduction in functionally identified afferent nerve fibres, Brain Res, 265, 233, 10.1016/0006-8993(83)90337-2
Pini, 1991, C-fibre function during the 6 weeks following brief application of capsaicin to a cutaneous nerve in the rat, Eur J Neurosci, 3, 274, 10.1111/j.1460-9568.1991.tb00089.x
Ramon y Cajal, 1995
Réthelyi, 1973, Distribution and connections of afferent fibers in the spinal cord, vol. 2, 237
Rivero-Melian, 1991, Choleragenoid horseradish peroxidase used for studying projections of some hindlimb cutaneous nerves and plantar foot afferents in the dorsal horn and Clarke’s column in the rat, Exp Brain Res, 84, 125, 10.1007/BF00231767
Robertson, 1985, A comparison between wheat germ agglutinin-and choleragenoid-horseradish peroxidase as anterogradely transported markers in central branches of primary sensory neurones in the rat with some observations in the cat, Neuroscience, 14, 895, 10.1016/0306-4522(85)90152-6
Sandkuhler, 2009, Models and mechanisms of hyperalgesia and allodynia, Physiol Rev, 89, 707, 10.1152/physrev.00025.2008
Sántha, 2003, Transganglionic transport of choleragenoid by capsaicin-sensitive C-fibre afferents to the substantia gelatinosa of the spinal dorsal horn after peripheral nerve section, Neuroscience, 116, 621, 10.1016/S0306-4522(02)00701-7
Sántha, 2010, Inhibition of glucosylceramide synthase reversibly decreases the capsaicin-induced activation and TRPV1 expression of cultured dorsal root ganglion neurons, Pain, 150, 103, 10.1016/j.pain.2010.04.006
Shehab, 2003, Evidence against cholera toxin B subunit as a reliable tracer for sprouting of primary afferents following peripheral nerve injury, Brain Res, 964, 218, 10.1016/S0006-8993(02)04001-5
Soares, 2002, Phosphorylated MAP1B is induced in central sprouting of primary afferents in response to peripheral injury but not in response to rhizotomy, Eur J Neurosci, 16, 593, 10.1046/j.1460-9568.2002.02126.x
South, 1988, Capsaicin application to central or peripheral vagal fibers attenuates CCK satiety, Peptides, 9, 601, 10.1016/0196-9781(88)90171-4
Szentágothai, 1964, Neuronal and synaptic arrangement in the substantia gelatinosa rolandi, J Comp Neurol, 122, 219, 10.1002/cne.901220207
Szigeti, 2012, Disparate changes in the expression of transient receptor potential vanilloid type 1 receptor mRNA and protein in dorsal root ganglion neurons following local capsaicin treatment of the sciatic nerve in the rat, Neuroscience, 10, 320, 10.1016/j.neuroscience.2011.10.058
Szoke, 2010, Effect of lipid raft disruption on TRPV1 receptor activation of trigeminal sensory neurons and transfected cell line, Eur J Pharmacol, 628, 67, 10.1016/j.ejphar.2009.11.052
Thakor, 2009, Increased peripheral nerve excitability and local NaV1.8 mRNA up-regulation in painful neuropathy, Mol Pain, 5, 14, 10.1186/1744-8069-5-14
Tong, 1999, Increased uptake and transport of cholera toxin B-subunit in dorsal root ganglion neurons after peripheral axotomy: possible implications for sensory sprouting, J Comp Neurol, 404, 143, 10.1002/(SICI)1096-9861(19990208)404:2<143::AID-CNE1>3.0.CO;2-#
Welk, 1983, Altered excitability of afferent C-fibers of the rat distal to a nerve site exposed to capsaicin, Neurosci Lett, 38, 245, 10.1016/0304-3940(83)90376-2
Willis, 1991
Winter, 1988, Nerve growth factor (NGF) regulates adult rat cultured dorsal root ganglion neuron responses to the excitotoxin capsaicin, Neuron, 1, 973, 10.1016/0896-6273(88)90154-7
Wood, 1988, Capsaicin-induced ion fluxes in dorsal root ganglion cells in culture, J Neurosci, 8, 3208, 10.1523/JNEUROSCI.08-09-03208.1988
Woodbury, 2008, Identity of myelinated cutaneous sensory neurons projecting to nocireceptive laminae following nerve injury in adult mice, J Comp Neurol, 508, 500, 10.1002/cne.21693
Woolf, 1992, Peripheral nerve injury triggers central sprouting of myelinated afferents, Nature, 355, 75, 10.1038/355075a0
Yip, 1984, The effects of nerve growth factor and its antiserum on the postnatal development and survival after injury of sensory neurons in rat dorsal root ganglia, J Neurosci, 4, 2986, 10.1523/JNEUROSCI.04-12-02986.1984