Low-dose effects and nonmonotonic dose–responses of endocrine disrupting chemicals: Has the case been made?

Regulatory Toxicology and Pharmacology - Tập 64 - Trang 130-133 - 2012
Lorenz R. Rhomberg1, Julie E. Goodman1
1Gradient, Cambridge, MA, USA

Tài liệu tham khảo

Doerge, 2011, Distribution of bisphenol A into tissues of adult, neonatal, and fetal Sprague-Dawley rats, Toxicol. Appl. Pharmacol., 255, 261, 10.1016/j.taap.2011.07.009 Elswick, 2000, Effect of different sampling designs on outcome of endocrine disruptor studies, Reprod. Toxicol., 14, 359, 10.1016/S0890-6238(00)00092-7 Elswick, 2001, Comments to the editor concerning the paper entitled “Reproductive malformation of the male offspring following maternal exposure to estrogenic chemicals” by C. Gupta, Exp. Biol. Med. (Maywood), 226, 74, 10.1177/153537020122600202 Goodman, 2010, A framework for assessing causality and adverse effects in humans with a case study of sulfur dioxide, Regul. Toxicol. Pharmacol., 58, 308, 10.1016/j.yrtph.2010.07.002 Goodman, 2009, Weight-of-evidence evaluation of reproductive and developmental effects of low doses of bisphenol A, Crit. Rev. Toxicol., 39, 1, 10.1080/10408440802157839 Kamrin, 2007, The ‘low dose’ hypothesis: validity and implications for human risk, Int. J. Toxicol., 26, 13, 10.1080/10915810601117968 Rhomberg, 2010, Hypothesis-based weight of evidence. A tool for evaluating and communicating uncertainties and inconsistencies in the large body of evidence in proposing a carcinogenic mode of action – naphthalene as an example, Crit. Rev. Toxicol., 40, 671, 10.3109/10408444.2010.499504 Sharpe, 2010, Is it time to end concerns over the estrogenic effects of bisphenol A?, Toxicol. Sci., 114, 1, 10.1093/toxsci/kfp299 US EPA, 2011 US Food and Drug Administration (US FDA), 2009. Memorandum to M. Hepp (Division of Food Contact Notifications, Regulatory Group 1) Re: Exposure to Bisphenol A (BPA) for Infants, Toddlers and Adults from the Consumption of Infant Formula, Toddler Food and Adult (Canned) Food, FDA-2010-N-0100-0001. Available at: <http://www.regulations.gov/#!documentDetail;D=FDA-2010-N-0100-0009>. Vandenberg, 2012, Hormones and endocrine-disrupting chemicals: low-dose effects and nonmonotonic dose responses, Endocr. Rev., 33, 378, 10.1210/er.2011-1050 vom Saal, 2006, Large effects from small exposures. II. The importance of positive controls in low-dose research on bisphenol A, Environ. Res., 100, 50, 10.1016/j.envres.2005.09.001 vom Saal, 2007, Chapel Hill Bisphenol A Expert Panel consensus statement: Integration of mechanisms, effects in animals and potential to impact human health at current levels of exposure, Reprod. Toxicol., 24, 131, 10.1016/j.reprotox.2007.07.005 Wolff, 2011, Correspondence re: Bisphenol A, Chem. Eng. News, 89, 4