Nitric oxide synthase inhibition ameliorates nicotine-induced sperm function decline in male rats

Marletta, 1993, Nitric oxide synthase structure and mechanism, J Biol Chem, 268, 12231, 10.1016/S0021-9258(18)31375-9 Agarwal, 2004, Role of antioxidants in treatment of male infertility: an overview of the literature, Reprod Biomed Online, 8, 616, 10.1016/S1472-6483(10)61641-0 Ignarro, 1990, Nitric oxide and cyclic GMP formation upon electrical field stimulation cause relaxation of corpus cavernosum smooth muscle, Biochem Biophys Res Commun, 170, 843, 10.1016/0006-291X(90)92168-Y Vanhatalo, 1996, Nitric oxide-synthesizing neurons originating at several different levels innervate rat penis, Neuroscience, 75, 891, 10.1016/0306-4522(96)00216-3 Garban, 1995, Restoration of normal adult penile erection response in aged rats by-long term treatment with androgens, Biol Reprod, 53, 1365, 10.1095/biolreprod53.6.1365 Penson, 1996, Androgen and pituitary control penile nitric oxide synthase and erectile function in rat, Biol Reprod, 55, 567, 10.1095/biolreprod55.3.567 Lugg, 1996, Cavernosal nerve stimulation in the rat reverses castration-induced decrease in penile NOS activity, Am J Physiol, 271, E354 Buhimschi, 1996, Differential regulation of nitric oxide in the rat uterus and cervix during pregnancy and labour, Hum Reprod, 11, 1755, 10.1093/oxfordjournals.humrep.a019481 Lewis, 1996, Nitric oxide synthase and nitrite production by human sperm: evidence that endogenous nitric oxide is beneficial to sperm motility, Mol Hum Reprod, 2, 873, 10.1093/molehr/2.11.873 Rosselli, 1995, Effect of nitric oxide on human spermatozoa: evidence that nitric oxide decreases sperm motility and induces sperm toxicity, Hum Reprod, 10, 1786, 10.1093/oxfordjournals.humrep.a136174 Oyeyipo, 2014, Nicotine alters serum antioxidant profile in male albino rats, North Am J Med Sci, 6, 168, 10.4103/1947-2714.131240 Raji, 2003, Implication of reproductive endocrine malfunction in male antifertility efficacy of Azadirachta indica extract in rats, Afr J Med Med Sci, 32, 159 Morrissey, 1988, Evaluation of rodent sperm, vaginal cytology, and reproductive organ weight data from National Toxicology Program 13-week studies, Fundam Appl Toxicol, 11, 343, 10.1016/0272-0590(88)90159-5 Wyrobek, 1980, The induction of sperm shape abnormalities in mice and humans, vol. 5, 257 Freund, 1964, Factors affecting haemocytometer count of sperm concentration in human semen, J Reprod Fertil, 8, 149, 10.1530/jrf.0.0080149 Dhawan, 2002, Prevention of chronic alcohol and nicotine-induced azospermia, sterility and decreased libido, by a novel tri-substituted benzoflavone moiety from Passiflora incarnata Linnaeus in healthy male rats, Life Sci, 71, 3059, 10.1016/S0024-3205(02)02168-9 Bolarinwa, 1993, Gastric acid secretion in pregnant and lactating rat, Trop Vet, 11, 35 Raji, 2006, Studies in the reproduction activities of method and extract of Ricinus communis seed in male albino rats, Asian J Androl, 8, 115, 10.1111/j.1745-7262.2006.00055.x Burnett, 1995, Localization of nitric oxide synthase in the reproductive organs of the male rat, Biol Reprod, 52, 1, 10.1095/biolreprod52.1.1 Zini, 1996, Immunohistochemical localization of endothelial nitric oxide synthase in human testis, epididymis and vas deferens suggest a possible role for nitric oxide in spermatogenesis, sperm maturation and programmed cell death, Biol Reprod, 55, 935, 10.1095/biolreprod55.5.935 Arnal, 1993, The vasodilatatory effect of endogenous nitric oxide is a major counterregulatory mechanism in the hypertensive rats, J Hypertens, 11, 945, 10.1097/00004872-199309000-00008 Ratnasooriya, 2000, Reduction in libido and fertility of male rats by administration of the nitric oxide (NO) synthase inhibitor N-nitro-l-arginine methyl ester, Int J Androl, 23, 187, 10.1046/j.1365-2605.2000.00225.x Oyeyipo, 2010, Effects of oral administration of nicotine on organ weight, serum testosterone level and testicular pathology in adult male rats, Niger J Physiol Sci, 25, 81 Oyeyipo, 2015, NG-nitro-l-arginine methylester protects against hormonal imbalances associated with nicotine administration in male rats, North Am J Med Sci, 7, 59, 10.4103/1947-2714.152080 Sharma, 1998, Effect of NG-nitro-l-arginine methyl ester on testicular blood flow and serum steroid hormones during sepsis, Shock, 9, 416, 10.1097/00024382-199806000-00005 Pinilla, 2001, Effects of systemic blockade of nitric oxide synthases on pulsatile LH, prolactin, and GH secretion in adult male rats, Horm Res, 55, 229, 10.1159/000050001 Kisa, 2004, Testicular tissue nitric oxide and thiobarbituric acid reactive substance levels: evaluation with respect to the pathogenesis of varicocele, Urol Res, 2, 196, 10.1007/s00240-004-0401-2 De Stefani, 2005, Experimental varicocele in the rat: early evaluation of the nitric oxide levels and histological alterations in the testicular tissue, Andrologia, 37, 115, 10.1111/j.1439-0272.2005.00660.x Oyeyipo, 2014, Antioxidant profile changes in reproductive tissues of rats treated with nicotine, J Hum Reprod Sci, 7, 41, 10.4103/0974-1208.130823 Mellis, 1995, Role of nitric oxide in penile erection and yawning induced by 5-HT1C receptor agonists in male rats, Naunyn Schmiedebergs Arch Pharmacol, 351, 439 Mooradian, 1987, Biological actions of androgens, Endocr Rev, 8, 1, 10.1210/edrv-8-1-1 Yeoman, 1998, Evidence for nitric oxide regulation of hamster sperm hyperactivation, J Androl, 19, 58 Romeo, 2001, Nitric oxide is increased in the spermatic vein of adolescents with left idiopathic varicocele, J Pediatr Surg, 36, 389, 10.1053/jpsu.2001.20724