Circulating SARS-CoV-2 spike N439K variants maintain fitness while evading antibody-mediated immunity
Emma C. Thomson1,2, Laura E. Rosen3, James G. Shepherd1, Roberto Spreafico3, Ana da Silva Filipe1, Jason A. Wojcechowskyj3, Chris Davis1, Luca Piccoli4, David J. Pascall5, Josh Dillen3, Spyros Lytras1, Nadine Czudnochowski3, Rajiv Shah1, Marcel Meury3, Natasha Jesudason1, Anna De Marco4, Kathy Li1, Jessica Bassi4, Aine O’Toole6, Dora Pinto4
1MRC-University of Glasgow Centre for Virus Research, University of Glasgow, Glasgow G61 1QH, UK
2Department of Clinical Research, London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK
3Vir Biotechnology, San Francisco, CA 94158, USA
4Humabs Biomed SA, A Subsidiary of Vir Biotechnology, 6500 Bellinzona, Switzerland
5Institute of Biodiversity, Animal Health and Comparative Medicine, Boyd Orr Centre for Population and Ecosystem Health, University of Glasgow, Glasgow G61 1QH, UK
6Institute of Evolutionary Biology, University of Edinburgh, Edinburgh EH9 3FL, UK