The coumaric acid and syringic acid ameliorate acetic acid-induced ulcerative colitis in rats via modulator of Nrf2/HO-1 and pro-inflammatory cytokines

Xia, 1998, Inflammatory bowel disease: definition, epidemiology, etiologic aspects, and immunogenetic studies, World J. Gastroenterol., 4, 446, 10.3748/wjg.v4.i5.446 Bernstein, 2008, Disorders of a modern lifestyle: reconciling the epidemiology of inflammatory bowel diseases, Gut, 57, 1185, 10.1136/gut.2007.122143 Molodecky, 2012, Increasing incidence and prevalence of the inflammatory bowel diseases with time, based on systematic review, Gastroenterology, 142, 46, 10.1053/j.gastro.2011.10.001 Abraham, 2009, Inflammatory bowel disease, N. Engl. J. Med., 361, 2066, 10.1056/NEJMra0804647 Kaluzna, 2022, The role of innate and adaptive immune cells in the pathogenesis and development of the inflammatory response in ulcerative colitis, J. Clin. Med., 11, 400, 10.3390/jcm11020400 Strober, 2011, Proinflammatory cytokines in the pathogenesis of inflammatory bowel diseases, Gastroenterology, 140, 1756, 10.1053/j.gastro.2011.02.016 Bourgonje, 2020, Oxidative stress and redox-modulating therapeutics in inflammatory bowel disease, Trends Mol. Med., 26, 1034, 10.1016/j.molmed.2020.06.006 Tian, 2017, Pathomechanisms of oxidative stress in inflammatory bowel disease and potential antioxidant therapies, Oxid. Med. Cell. Longev., 2017, 10.1155/2017/4535194 Sabzevary-Ghahfarokhi, 2018, The regulatory role of Nrf2 in antioxidants phase2 enzymes and IL-17A expression in patients with ulcerative colitis, Pathol. Res. Pract., 214, 1149, 10.1016/j.prp.2018.06.001 Lu, 2016, An inhibitor of the Keap1-Nrf2 protein-protein interaction protects NCM460 colonic cells and alleviates experimental colitis, Sci. Rep., 6, 26585, 10.1038/srep26585 Ma, 2013, Role of nrf2 in oxidative stress and toxicity, Annu. Rev. Pharmacol. Toxicol., 53, 401, 10.1146/annurev-pharmtox-011112-140320 Taguchi, 2011, Molecular mechanisms of the Keap1–Nrf2 pathway in stress response and cancer evolution, Genes Cells, 16, 123, 10.1111/j.1365-2443.2010.01473.x Kansanen, 2013, The Keap1-Nrf2 pathway: mechanisms of activation and dysregulation in cancer, Redox Biol., 1, 45, 10.1016/j.redox.2012.10.001 Vauzour, 2010, Polyphenols and human health: prevention of disease and mechanisms of action, Nutrients, 2, 1106, 10.3390/nu2111106 Srinivasulu, 2018, Syringic acid (SA)-a review of its occurrence, biosynthesis, pharmacological and industrial importance, Biomed. Pharmacother. = Biomedecine & pharmacotherapie., 108, 547, 10.1016/j.biopha.2018.09.069 Shen, 2019, Protective effects of p-coumaric acid against oxidant and hyperlipidemia-an in vitro and in vivo evaluation, Biomed. Pharmacother. = Biomedecine & pharmacotherapie, 111, 579, 10.1016/j.biopha.2018.12.074 Mirza, 2022, Syringic acid ameliorates cardiac, hepatic, renal and neuronal damage induced by chronic hyperglycaemia in Wistar rats: a behavioural, biochemical and histological analysis, Molecules, 27, 6722, 10.3390/molecules27196722 Wallace, 1990, An orally active inhibitor of leukotriene synthesis accelerates healing in a rat model of colitis, Am. J. Phys. Anthropol., 258, G527 Dieleman, 1998, Chronic experimental colitis induced by dextran sulphate sodium (DSS) is characterized by Th1 and Th2 cytokines, Clin. Exp. Immunol., 114, 385, 10.1046/j.1365-2249.1998.00728.x Kazemian, 2022, Correlation of miR-24-3p and miR-595 expression with CCL3, CCL4, IL1-beta, TNFalphaIP3, and NF-kappaBIalpha genes in PBMCs of patients with coronary artery disease, EXCLI J., 21, 1184 Farid, 2022, Evaluation of anti-inflammatory effects of leaf and seed extracts of Plantago major on acetic acid-induced ulcerative colitis in rats, J. Ethnopharmacol., 298, 10.1016/j.jep.2022.115595 Mehrabani, 2012, The healing effect of Teucrium polium in acetic acid-induced ulcerative colitis in the dog as an animal model, Middle East J. Dig. Dis., 4, 40 Alsharif, 2022, Miconazole mitigates acetic acid-induced experimental colitis in rats: insight into inflammation, oxidative stress and Keap1/Nrf-2 signaling crosstalk, Biology 11, 303, 10.3390/biology11020303 Liu, 2018, NF-κB and Nrf2 pathways contribute to the protective effect of Licochalcone A on dextran sulphate sodium-induced ulcerative colitis in mice, Biomed. Pharmacother. = Biomedecine & pharmacotherapie, 102, 922, 10.1016/j.biopha.2018.03.130 Surh, 2008, NF-kappa B and Nrf2 as potential chemopreventive targets of some anti-inflammatory and antioxidative phytonutrients with anti-inflammatory and antioxidative activities, Asia Pac. J. Clin. Nutr., 17, 269 Wang, 2011, Proanthocyanidins from grape seeds modulates the nuclear factor-kappa B signal transduction pathways in rats with TNBS-induced recurrent ulcerative colitis, Int. Immunopharmacol., 11, 1620, 10.1016/j.intimp.2011.05.024 Podolsky, 2002, Inflammatory bowel disease, N. Engl. J. Med., 347, 417, 10.1056/NEJMra020831 Mao, 2018, The role of NLRP3 and IL-1β in the pathogenesis of inflammatory bowel disease, Front. Immunol., 9, 2566, 10.3389/fimmu.2018.02566 De Santis, 2017, TNFα deficiency results in increased IL-1β in an early onset of spontaneous murine colitis, Cell Death Dis., 8, e2993, 10.1038/cddis.2017.397 Tatiya-Aphiradee, 2018, Immune response and inflammatory pathway of ulcerative colitis, J. Basic Clin. Physiol. Pharmacol., 30, 1, 10.1515/jbcpp-2018-0036 Ghasemi-Dehnoo, 2022, Coumaric acid ameliorates experimental colitis in rats through attenuation of oxidative stress, inflammatory response and apoptosis, Inflammopharmacology, 30, 2359, 10.1007/s10787-022-01074-z Maurer, 2020, Grape peel powder attenuates the inflammatory and oxidative response of experimental colitis in rats by modulating the NF-kappaB pathway and activity of antioxidant enzymes, Nutr. Res., 76, 52, 10.1016/j.nutres.2020.01.006 Shahid, 2022, Sinapic acid ameliorates acetic acid-induced ulcerative colitis in rats by suppressing inflammation, oxidative stress, and apoptosis, Molecules, 27, 4139, 10.3390/molecules27134139