Key role of endothelium in the eNOS-dependent cardioprotection with exercise training

Journal of Molecular and Cellular Cardiology - Tập 102 - Trang 26-30 - 2017
C. Farah1, A. Nascimento2,3, G. Bolea2, G. Meyer2, S. Gayrard2, A. Lacampagne1, O. Cazorla1, C. Reboul2
1CNRS UMR9214, INSERM U1046, Université de Montpellier, F-34295 Montpellier, France
2EA4278, LaPEC, Université d'Avignon, F-84000 Avignon, France
3CAPES Foundation, Ministry of Education of Brazil, Brasília, DF 70040-020, Brazil

Tài liệu tham khảo

Powers, 2008, Exercise-induced cardioprotection against myocardial ischemia-reperfusion injury, Free Radic. Biol. Med., 44, 193, 10.1016/j.freeradbiomed.2007.02.006 French, 2008, Exercise-induced protection against myocardial apoptosis and necrosis: MnSOD, calcium-handling proteins, and calpain, FASEB J., 22, 2862, 10.1096/fj.07-102541 Alleman, 2016, Exercise-induced protection against reperfusion arrhythmia involves stabilization of mitochondrial energetics, Am. J. Physiol. Heart Circ. Physiol., 310, H1360, 10.1152/ajpheart.00858.2015 Farah, 2013, Exercise-induced cardioprotection: a role for eNOS uncoupling and NO metabolites, Basic Res. Cardiol., 108, 389, 10.1007/s00395-013-0389-2 Calvert, 2011, Exercise protects against myocardial ischemia-reperfusion injury via stimulation of β(3)-adrenergic receptors and increased nitric oxide signaling: role of nitrite and nitrosothiols, Circ. Res., 108, 1448, 10.1161/CIRCRESAHA.111.241117 Simon, 2014, Nitric oxide synthase regulation of cardiac excitation-contraction coupling in health and disease, J. Mol. Cell. Cardiol., 73, 80, 10.1016/j.yjmcc.2014.03.004 Balligand, 1995, Nitric oxide-dependent parasympathetic signaling is due to activation of constitutive endothelial (type III) nitric oxide synthase in cardiac myocytes, J. Biol. Chem., 270, 14582, 10.1074/jbc.270.24.14582 Gödecke, 2001, Inotropic response to beta-adrenergic receptor stimulation and anti-adrenergic effect of ACh in endothelial NO synthase-deficient mouse hearts, J. Physiol., 532, 195, 10.1111/j.1469-7793.2001.0195g.x Yang, 2013, Early ischaemic preconditioning requires Akt- and PKA-mediated activation of eNOS via serine1176 phosphorylation, Cardiovasc. Res., 97, 33, 10.1093/cvr/cvs287 Aït Mou, 2009, Late exercise training improves non-uniformity of transmural myocardial function in rats with ischaemic heart failure, Cardiovasc. Res., 81, 555, 10.1093/cvr/cvn229 Portal, 2013, A model of hypoxia-reoxygenation on isolated adult mouse cardiomyocytes: characterization, comparison with ischemia-reperfusion, and application to the cardioprotective effect of regular treadmill exercise, J. Cardiovasc. Pharmacol. Ther., 18, 367, 10.1177/1074248412475158 Laughlin, 2012, The coronary circulation in exercise training, AJP Heart Circ. Physiol., 302, H10, 10.1152/ajpheart.00574.2011 Griffin, 2001, Endothelium-mediated relaxation of porcine collateral-dependent arterioles is improved by exercise training, Circulation, 104, 1393, 10.1161/hc3601.094274 Zhou, 2010, Effects of exercise training on cellular mechanisms of endothelial nitric oxide synthase regulation in coronary arteries after chronic occlusion, Am. J. Physiol. Heart Circ. Physiol., 298, H1857, 10.1152/ajpheart.00754.2009 Leucker, 2013, Impairment of endothelial-myocardial interaction increases the susceptibility of cardiomyocytes to ischemia/reperfusion injury, PLoS One, 8, 10.1371/journal.pone.0070088