Basal ganglia and cerebellar loops: motor and cognitive circuits

Brain Research Reviews - Tập 31 - Trang 236-250 - 2000
Frank A Middleton1, Peter L Strick1,2,3
1Research Service (151S), VA Medical Center, 800 Irving Ave, Syracuse, NY 13210, USA.
2Department of Neurosurgery, State University of New York Health Science Center at Syracuse, Syracuse, NY USA
3Department of Neuroscience/Physiology, State University of New York Health Science Center at Syracuse, Syracuse, NY USA

Tài liệu tham khảo

Akshoomoff, 1992, A new role for the cerebellum in cognitive function, Behav. Neurosci., 106, 731, 10.1037/0735-7044.106.5.731 Alexander, 1986, Parallel organization of functionally segregated circuits linking basal ganglia and cortex, Annu. Rev. Neurosci., 9, 357, 10.1146/annurev.ne.09.030186.002041 Allen, 1974, Cerebrocerebellar communication systems, Physiol. Rev., 54, 957, 10.1152/physrev.1974.54.4.957 Allen, 1978, Convergence of cerebral inputs onto dentate neurons in monkey, Exp. Brain Res., 32, 151, 10.1007/BF00239724 Anderson, 1992, Postmortem analysis of subcortical monamines and amino acids in Tourette syndrome, Adv. Neurol., 58, 123 Anderson, 1985, Influence of the globus pallidus on arm movements in monkeys. III. Timing of movement-related information, J. Neurophysiol., 54, 433, 10.1152/jn.1985.54.2.433 Andreasen, 1996, Schizophrenia and cognitive dysmetria: a positron-emission tomography study of dysfunctional prefrontal-thalamic-cerebellar circuitry, Proc. Natl. Acad. Sci. USA, 93, 9985, 10.1073/pnas.93.18.9985 Andreasen, 1992, Hypofrontality in neuroleptic-naive patients and in patients with chronic schizophrenia, Arch. Gen. Psych., 49, 943, 10.1001/archpsyc.1992.01820120031006 Arnold, 1996, Recent advances in defining the neuropathology of schizophrenia, Acta Neuropathol., 92, 217, 10.1007/s004010050512 Asanuma, 1983, Distribution of cerebellar terminations in the ventral lateral thalamic region of the monkey, Brain Res. Rev., 5, 237, 10.1016/0165-0173(83)90015-2 Baker, 1996, Neural systems engaged by planning: a PET study of the Tower of London task, Neuropsychologia, 34, 515, 10.1016/0028-3932(95)00133-6 Bauman, 1985, Histoanatomic observations of the brain in early infantile autism, Neurology, 35, 866, 10.1212/WNL.35.6.866 L.R. Baxter, Neuroimaging studies of obsessive compulsive disorder, in: M.A. Jenike (Ed.), Psychiatric Clinics of North America. Obsessional disorders, Saunders, Philadelphia, 1992, pp. 871–884. Bejjani, 1998, Acute major depression induced by localized electrical stimulation in the human upper midbrain, Soc. Neurosci. Abstr., 24, 227 Berman, 1992, Regional cerebral blood flow in monozygotic twins discordant and concordant for schizophrenia, Arch. Gen. Psych., 49, 927, 10.1001/archpsyc.1992.01820120015004 Bhatia, 1994, The behavioural and motor consequences of focal lesions of the basal ganglia in man, Brain, 117, 859, 10.1093/brain/117.4.859 Botez, 1989, Role of the cerebellum in complex human behavior, Ital. J. Neurol. Sci., 10, 291, 10.1007/BF02333774 Breier, 1992, Brain morphology and schizophrenia. A magnetic resonance imaging study of limbic, prefrontal cortex, and caudate structures, Arch. Gen. Psych., 49, 921, 10.1001/archpsyc.1992.01820120009003 V.B. Brooks, W.T. Thach, Cerebellar control of posture and movement, in: V.B. Brooks (Ed.), Handbook of physiology, Section 1. The nervous system, Vol. 2, Motor control, Part II, American Physiological Society, Bethesda, 1981, pp. 877–946. Bruce, 1985, Primate frontal eye fields. II. Physiological and anatomical correlates of electrically evoked eye movements, J. Neurophysiol., 54, 714, 10.1152/jn.1985.54.3.714 Buchanan, 1993, Structural abnormalities in deficit and nondeficit schizophrenia, Am. J. Psych., 150, 59, 10.1176/ajp.150.1.59 Buchsbaum, 1992, Frontostriatal disorder of cerebral metabolism in never-medicated schizophrenics, Arch. Gen. Psych., 49, 935, 10.1001/archpsyc.1992.01820120023005 Butters, 1978, Comparison of the neuropsychological deficits associated with early and advanced Huntington's disease, Arch. Neurol., 35, 585, 10.1001/archneur.1978.00500330033006 Casey, 1997, Implication of right frontostriatal circuitry in response inhibition and attention-deficit/hyperactivity disorder, J. Am. Acad. Child Adolesc. Psych., 36, 374, 10.1097/00004583-199703000-00016 Castellanos, 1996, Quantitative brain magnetic resonance imaging in attention-deficit hyperactivity disorder, Arch. Gen. Psych., 53, 607, 10.1001/archpsyc.1996.01830070053009 Courchesne, 1991, Neuroanatomic imaging in autism, Pediatrics, 87, 781, 10.1542/peds.87.5.781 Courchesne, 1997, Brainstem, cerebellar and limbic neuroanatomical abnormalities in autism, Curr. Opin. Neurobiol., 7, 269, 10.1016/S0959-4388(97)80016-5 Courchesne, 1988, Hypoplasia of cerebellar vermal lobules VI and VII in autism, N. Engl. J. Med., 318, 1349, 10.1056/NEJM198805263182102 Csernansky, 1991, Limbic/mesolimbic connections and the pathogenesis of schizophrenia, Soc. Biol. Psych., 30, 383, 10.1016/0006-3223(91)90295-W Cummings, 1993, Frontal-subcortical circuits and human behavior, Arch. Neurol., 50, 873, 10.1001/archneur.1993.00540080076020 DeLong, 1971, Activity of pallidal neurons during movement, J. Neurophysiol., 34, 414, 10.1152/jn.1971.34.3.414 M.R. DeLong, A.P. Georgopoulos, Motor functions of the basal ganglia, in: V.B. Brooks (Ed.), Handbook of Physiology, Section 1. The Nervous System, Vol. 2, Motor Control, Part II, American Physiological Society, Bethesda, 1981, pp. 1017–1061. DeLong, 1985, Primate globus pallidus and subthalamic nucleus: functional organization, J. Neurophysiol., 53, 530, 10.1152/jn.1985.53.2.530 Dewan, 1983, Cerebellar morphology in chronic schizophrenic patients: a controlled computed tomography study, Psych. Res., 10, 97, 10.1016/0165-1781(83)90108-7 Dewick, 1991, Perception and memory for faces in Parkinson's disease, Neuropsychologia, 29, 785, 10.1016/0028-3932(91)90072-G Divac, 1967, Behavioral effects of selective ablation of the caudate nucleus, J. Comp. Physiol. Psychol., 63, 184, 10.1037/h0024348 Dubois, 1997, Cognitive deficits in Parkinson's disease, J. Neurol., 244, 2, 10.1007/PL00007725 Early, 1987, Left globus pallidus abnormality in never-medicated patients with schizophrenia, Proc. Natl. Acad. Sci. USA, 84, 561, 10.1073/pnas.84.2.561 Ebert, 1993, A test-retest study of cerebral blood flow during somatosensory stimulation in depressed patients with schizophrenia and major depression, Eur. Arch. Psych. Clin. Neurosci., 242, 250, 10.1007/BF02189972 Evarts, 1969, Motor mechanisms of the CNS: cerebrocerebellar interrelations, Annu. Rev. Physiol., 31, 451, 10.1146/annurev.ph.31.030169.002315 Farina, 1994, Frontal dysfunction in early Parkinson's disease, Acta Neurol. Scand., 90, 34, 10.1111/j.1600-0404.1994.tb02676.x Fiez, 1992, Impaired non-motor learning and error detection associated with cerebellar damage, Brain, 115, 155, 10.1093/brain/115.1.155 Fiez, 1996, A positron emission tomography study of the short-term maintenance of verbal information, J. Neurosci., 16, 808, 10.1523/JNEUROSCI.16-02-00808.1996 Filipek, 1997, Volumetric MRI analysis comparing subjects having attention-deficit hyperactivity disorder with normal controls, Neurology, 48, 589, 10.1212/WNL.48.3.589 Funahashi, 1989, Mnemonic coding of visual space in the monkeys dorsolateral prefrontal cortex, J. Neurophysiol., 61, 331, 10.1152/jn.1989.61.2.331 Funahashi, 1997, Delay-period activity in the primate prefrontal cortex encoding multiple spatial positions and their order of presentation, Behav. Brain Res., 84, 203, 10.1016/S0166-4328(96)00151-9 J.M. Fuster, The Prefrontal Cortex, Raven Press, New York, 1997. Fuster, 1971, Neuron activity related to short-term memory, Science, 173, 652, 10.1126/science.173.3997.652 Fuster, 1982, Cellular discharge in the dorsolateral prefrontal cortex of the monkey in cognitive tasks, Exp. Neurol., 77, 679, 10.1016/0014-4886(82)90238-2 Gaffney, 1989, Forebrain structure in infantile autism, J. Am. Acad. Child Adolesc. Psych., 8, 534, 10.1097/00004583-198907000-00011 Gao, 1996, Cerebellum implicated in sensory acquisition and discrimination rather than motor control, Science, 272, 545, 10.1126/science.272.5261.545 P.S. Goldman-Rakic, Circuitry of primate prefrontal cortex and regulation of behavior by representational memory, in: F. Plum (Ed.), Handbook of Physiology, Section 1. The Nervous System, Vol V, American Physiological Society, Bethesda, 1987, pp. 373–413. Grafman, 1992, Cognitive planning deficit in patients with cerebellar atrophy, Neurology, 42, 1493, 10.1212/WNL.42.8.1493 C.G. Gross, Visual functions of inferotemporal cortex, in: R. Jung (Ed.), Handbook of Sensory Physiology, Springer-Verlag, Berlin, 1972, pp. 451–482. Hamada, 1990, Activity of identified wrist-related pallidal neurons during step and ramp wrist movements in the monkey, J. Neurophysiol., 64, 1892, 10.1152/jn.1990.64.6.1892 Hamilton, 1983, Psychiatric symptoms and cerebellar pathology, Am. J. Psych., 140, 1322, 10.1176/ajp.140.10.1322 Hashimoto, 1993, Brainstem and cerebellar vermis involvement in autistic children, J. Child. Neurol., 8, 149, 10.1177/088307389300800207 Heath, 1979, Gross pathology of the cerebellum in patients diagnosed and treated as functional psychiatric disorders, J. Nerv. Ment. Dis., 167, 585, 10.1097/00005053-197910000-00001 Heckers, 1991, Cortex, white matter, and basal ganglia in schizophrenia: a volumetric postmortem study, Biol. Psych., 29, 556, 10.1016/0006-3223(91)90091-Y Heindel, 1989, Neuropsychological evidence for multiple implicit memory systems: a comparison of Alzheimer's, Huntington's, and Parkinson's disease patients, J. Neurosci., 9, 582, 10.1523/JNEUROSCI.09-02-00582.1989 Hikosaka, 1983, Visual and oculomotor functions of monkey substantia nigra pars reticulata. I. Relation of visual and auditory responses to saccades, J. Neurophysiol., 49, 1230, 10.1152/jn.1983.49.5.1230 Hikosaka, 1993, Effects of caudate nucleus stimulation on substantia nigra cell activity in monkey, Exp. Brain Res., 95, 457, 10.1007/BF00227139 Holmes, 1939, The cerebellum of man, Brain, 30, 466, 10.1093/brain/30.4.466 Holroyd, 1991, Autistic features in Joubert syndrome: a genetic disorder with agenesis of the cerebellar vermis, Biol. Psych., 29, 287, 10.1016/0006-3223(91)91291-X Hoover, 1993, Multiple output channels in the basal ganglia, Science, 259, 819, 10.1126/science.7679223 Hoover, 1999, The organization of cerebello- and pallido-thalamic projections to primary motor cortex: an investigation employing retrograde transneuronal transport of herpes simplex virus type 1, J. Neurosci., 19, 1446, 10.1523/JNEUROSCI.19-04-01446.1999 Hutton, 1998, Smooth pursuit and saccadic abnormalities in first-episode schizophrenia, Psychol. Med., 28, 685, 10.1017/S0033291798006722 Hutton, 1998, Oculomotor abnormalities in schizophrenia: a critical review, Neurology, 50, 604, 10.1212/WNL.50.3.604 Ilinsky, 1985, Organization of the nigrothalamocortical system in the rhesus monkey, J. Comp. Neurol., 236, 315, 10.1002/cne.902360304 Insel, 1992, Toward a neuroanatomy of obsessive-compulsive disorder, Arch. Gen. Psych., 49, 739, 10.1001/archpsyc.1992.01820090067011 Ivry, 1989, Timing functions of the cerebellum, J. Cog. Neurosci., 1, 136, 10.1162/jocn.1989.1.2.136 Jacobs, 1995, Impaired perception of facial identity and facial affect in Huntington's disease, Neurology, 45, 1217, 10.1212/WNL.45.6.1217 Jacobs, 1995, Emotional facial imagery, perception, and expression in Parkinson's disease, Neurology, 45, 1696, 10.1212/WNL.45.9.1696 Jenkins, 1994, Motor sequence learning: a study with positron emission tomography, J. Neurosci., 14, 3775, 10.1523/JNEUROSCI.14-06-03775.1994 Jernigan, 1991, Magnetic resonance imaging abnormalities in lenticular nuclei and cerebral cortex in schizophrenia, Arch. Gen. Psych., 48, 881, 10.1001/archpsyc.1991.01810340013002 Joseph, 1985, Brainstem and vermis atrophy in catatonia, Am. J. Psych., 142, 352, 10.1176/ajp.142.3.352 Jueptner, 1997, Anatomy of motor learning. II. Subcortical structures and learning by trial and error, J. Neurophysiol., 77, 1325, 10.1152/jn.1997.77.3.1325 Jueptner, 1997, Anatomy of motor learning. I. Frontal cortex and attention to action, J. Neurophysiol., 77, 1313, 10.1152/jn.1997.77.3.1313 Jurjus, 1994, Schizophrenia-like psychosis and cerebellar degeneration, Schizophr. Res., 12, 183, 10.1016/0920-9964(94)90076-0 Kemp, 1971, The connexions of the striatum and globus pallidus: synthesis and speculation, Phil. Trans. R. Soc. London Ser., B 262, 441, 10.1098/rstb.1971.0106 Kim, 1994, Activation of a cerebellar output nucleus during cognitive processing, Science, 265, 949, 10.1126/science.8052851 Kish, 1988, Uneven pattern of dopamine loss in the striatum of patients with idiopathic Parkinson's disease. Pathophysiologic and clinical implications, N. Eng. J. Med., 318, 876, 10.1056/NEJM198804073181402 Kubota, 1985, Neuron activities of monkey prefrontal cortex during the learning of visual discrimination tasks with GO/NO-GO performances, Neurosci. Res., 3, 106, 10.1016/0168-0102(85)90025-2 Kubota, 1971, Prefrontal cortical unit activity and delayed alternation performance in monkeys, J. Neurophysiol., 34, 337, 10.1152/jn.1971.34.3.337 Laplane, 1989, Obsessive-compulsive and other behavioural changes with bilateral basal ganglia lesions, Brain, 112, 699, 10.1093/brain/112.3.699 Lawrence, 1996, Executive and mnemonic functions in early Huntington's disease, Brain, 119, 1633, 10.1093/brain/119.5.1633 Leiner, 1986, Does the cerebellum contribute to mental skills?, Behav. Neurosci., 100, 443, 10.1037/0735-7044.100.4.443 Leiner, 1987, Cerebro-cerebellar learning loops in apes and humans, Ital. J. Neurol. Sci., 8, 425, 10.1007/BF02334599 Leiner, 1989, Reappraising the cerebellum: what does the hindbrain contribute to the forebrain?, Behav. Neurosci., 103, 998, 10.1037/0735-7044.103.5.998 Leiner, 1991, The human cerebro-cerebellar system: its computing, cognitive, and language skills, Behav. Brain. Res., 44, 113, 10.1016/S0166-4328(05)80016-6 Leiner, 1993, Cognitive and language functions of the human cerebellum, Trends Neurosci., 16, 444, 10.1016/0166-2236(93)90072-T Levin, 1989, Cognitive impairments associated with early Parkinson's disease, Neurology, 39, 557, 10.1212/WNL.39.4.557 Liddle, 1992, Patterns of cerebral blood flow in schizophrenia, Br. J. Psych., 160, 179, 10.1192/bjp.160.2.179 Lynch, 1994, Input to the primate frontal eye field from the substantia nigra, superior colliculus, and dentate nucleus demonstrated by transneuronal transport, Exp. Brain Res., 100, 181, 10.1007/BF00227293 Martin, 1995, Cerebellum and schizophrenia: a selective review, Schiz. Bull., 21, 241, 10.1093/schbul/21.2.241 McGuire, 1994, Functional anatomy of obsessive-compulsive phenomena, Br. J. Psych., 164, 459, 10.1192/bjp.164.4.459 McKee, 1990, Peduncular hallucinosis associated with isolated infarction of the substantia nigra pars reticulata, Ann. Neurol., 27, 500, 10.1002/ana.410270508 Middleton, 1994, Anatomical evidence for cerebellar and basal ganglia involvement in higher cognitive function, Science, 266, 458, 10.1126/science.7939688 Middleton, 1996, The temporal lobe is a target of output from the basal ganglia, Proc. Natl. Acad. Sci. USA, 93, 8683, 10.1073/pnas.93.16.8683 Middleton, 1997, New concepts about the organization of basal ganglia output, Adv. Neurol., 74, 57 Middleton, 1997, Dentate output channels: motor and cognitive components, Prog. Brain Res., 114, 555 Middleton, 1997, Cerebellar output channels, Int. Rev. Neurobiol., 41, 61, 10.1016/S0074-7742(08)60347-5 Middleton, 1998, Cerebellar output: motor and cognitive channels, Trends Cog. Sci., 2, 348, 10.1016/S1364-6613(98)01220-0 F.A. Middleton, P.L. Strick, Basal ganglia output and cognition: evidence from anatomical, behavioral and clinical studies, Brain Cogn. (in press). Mink, 1991, Basal ganglia motor control: I. Nonexclusive relation of pallidal discharge to five movement modes, J. Neurophysiol., 65, 273, 10.1152/jn.1991.65.2.273 Miyachi, 1997, Differential roles of monkey striatum in learning of sequential hand movement, Exp. Brain Res., 115, 1, 10.1007/PL00005669 Miyashita, 1993, Inferior temporal cortex: where visual perception meets memory, Annu. Rev. Neurosci., 16, 245, 10.1146/annurev.ne.16.030193.001333 Miyata, 1983, HRP studies on thalamocortical neurons related to the cerebellocerebral projection in the monkey, Brain Res., 274, 213, 10.1016/0006-8993(83)90698-4 Modell, 1989, Neurophysiologic dysfunction in basal ganglia/limbic striatal and thalamocortical circuits as a pathogenetic mechanism of obsessive-compulsive disorder, J. Neuropsych., 1, 27, 10.1176/jnp.1.1.27 Molinari, 1997, Cerebellum and procedural learning: evidence from focal cerebellar lesions, Brain, 120, 1753, 10.1093/brain/120.10.1753 Mushiake, 1993, Preferential activity of dentate neurons during limb movements guided by vision, J. Neurophysiol., 70, 2660, 10.1152/jn.1993.70.6.2660 Mushiake, 1995, Pallidal neuron activity during sequential arm movements, J. Neurophysiol., 74, 2754, 10.1152/jn.1995.74.6.2754 Mushiake, 1995, Cerebellar and pallidal activity during instructed delay periods, Soc. Neurosci. Abstr., 21, 411 Nasrallah, 1991, Perinatal brain injury and cerebellar vermal lobules I–X in schizophrenia, Biol. Psych., 29, 567, 10.1016/0006-3223(91)90092-Z Niki, 1976, Prefrontal unit activity and delayed response: relation to cue location versus direction of response, Brain Res., 105, 79, 10.1016/0006-8993(76)90924-0 J. Olszewski, The Thalamus of Macaca Mulatta. An Atlas for Use with the Stereotaxic Instrument, Karger, Basel, 1952. Orioli, 1989, Cerebellar connections with the motor cortex and the arcuate premotor area: an analysis employing retrograde transneuronal transport of WGA-HRP, J. Comp. Neurol., 288, 612, 10.1002/cne.902880408 Owen, 1993, Visuospatial memory deficits at different stages of Parkinson's disease, Neuropsychologia, 31, 627, 10.1016/0028-3932(93)90135-M Owen, 1998, Abnormal basal ganglia outflow in Parkinson's disease identified with PET. Implications for higher cortical functions, Brain, 121, 949, 10.1093/brain/121.5.949 Owen, 1996, Planning and spatial working memory: a positron emission tomography study in humans, Eur. J. Neurosci., 8, 353, 10.1111/j.1460-9568.1996.tb01219.x Owen, 1992, Fronto-striatal cognitive deficits at different stages of Parkinson's disease, Brain, 115, 1727, 10.1093/brain/115.6.1727 Palfi, 1996, Chronic 3-nitropropionic acid treatment in baboons replicates the cognitive and motor deficits of Huntington's disease, J. Neurosci., 16, 3019, 10.1523/JNEUROSCI.16-09-03019.1996 Park, 1992, Schizophrenics show spatial working memory deficits, Arch. Gen. Psych., 49, 975, 10.1001/archpsyc.1992.01820120063009 Partiot, 1996, Delayed response tasks in basal ganglia lesions in man: further evidence for a striato-frontal cooperation in behavioural adaptation, Neuropsychologia, 34, 709, 10.1016/0028-3932(95)00143-3 Pascual-Leone, 1993, Procedural learning in Parkinson's disease and cerebellar degeneration, Ann. Neurol., 34, 594, 10.1002/ana.410340414 R. Passingham, The frontal lobes and voluntary action, Oxford University Press, Oxford, 1993. Petersen, 1988, Positron emission tomographic studies of the cortical anatomy of single-word processing, Nature, 331, 585, 10.1038/331585a0 Raichle, 1994, Practice-related changes in human brain functional anatomy during nonmotor learning, Cereb. Cortex, 4, 8, 10.1093/cercor/4.1.8 Rispal-Padel, 1982, Cerebellar nuclear topography of simple and synergistic movements in the alert baboon (Papio papio), Exp. Brain Res., 47, 365, 10.1007/BF00239355 Robinson, 1995, Reduced caudate nucleus volume in obsessive-compulsive disorder, Arch. Gen. Psych., 52, 393, 10.1001/archpsyc.1995.03950170067009 Roeltgen, 1994, Task persistence and learning ability in normal and chronic low dose MPTP-treated monkeys, Behav. Brain Res., 60, 115, 10.1016/0166-4328(94)90138-4 Rouiller, 1994, Cerebellothalamocortical and pallidothalamocortical projections to the primary and supplementary motor cortical areas: a multiple tracing study in macaque monkeys, J. Comp. Neurol., 345, 185, 10.1002/cne.903450204 Saint-Cyr, 1988, Procedural learning and neostriatal dysfunction in man, Brain, 111, 941, 10.1093/brain/111.4.941 Saint-Cyr, 1990, Organization of visual cortical inputs to the striatum and subsequent outputs to the pallido-nigral complex in the monkey, J. Comp. Neurol., 298, 129, 10.1002/cne.902980202 Sasaki, 1976, Electrophysiological studies on the cerebello-cerebral projections in monkeys, Exp. Brain Res., 24, 495, 10.1007/BF00234966 Sasaki, 1979, Projection of the cerebellar dentate nucleus onto the frontal association cortex in monkeys, Exp. Brain Res., 37, 193, 10.1007/BF01474266 Schmahmann, 1991, An emerging concept. The cerebellar contribution to higher function, Arch. Neurol., 48, 1178, 10.1001/archneur.1991.00530230086029 Schmahmann, 1997, Rediscovery of an early concept, Int. Rev. Neurobiol., 41, 3, 10.1016/S0074-7742(08)60345-1 Schmahmann, 1997, Anatomic organization of the basilar pontine projections from prefrontal cortices in rhesus monkey, J. Neurosci., 17, 438, 10.1523/JNEUROSCI.17-01-00438.1997 Schmahmann, 1997, The cerebrocerebellar system, Int. Rev. Neurobiol., 41, 31, 10.1016/S0074-7742(08)60346-3 Schneider, 1995, Cognitive deficits precede motor deficits in a slowly progressing model of parkinsonism in the monkey, Neurodegen., 4, 245, 10.1016/1055-8330(95)90014-4 Schneider, 1993, Delayed matching-to-sample, object retrieval, and discrimination reversal deficits in chronic low dose MPTP-treated monkeys, Brain Res., 615, 351, 10.1016/0006-8993(93)90049-S Schwartz, 1996, Systematic changes in cerebral glucose metabolic rate after successful behavior modification treatment of obsessive-compulsive disorder, Arch. Gen. Psych., 53, 109, 10.1001/archpsyc.1996.01830020023004 Selemon, 1995, Abnormally high neuronal density in the schizophrenic cortex. A morphometric analysis of prefrontal area 9 and occipital area 17, Arch. Gen. Psych., 52, 805, 10.1001/archpsyc.1995.03950220015005 R.C. Shelton, D.R. Weinberger, X-ray computerized tomography studies in schizophrenia: a review and synthesis, in: H.A. Nasrallah, D.R. Weinberger (Eds.), Handbook of Schizophrenia, Elsevier, New York, 1986, pp. 207–250. Siegel, 1993, Cortical-striatal-thalamic circuits and brain glucose metabolic activity in 70 unmedicated male schizophrenic patients, Am. J. Psych., 150, 1325, 10.1176/ajp.150.9.1325 Silbersweig, 1995, A functional neuroanatomy of hallucinations in schizophrenia, Nature, 378, 176, 10.1038/378176a0 Snider, 1982, Cerebellar pathology in schizophrenia — cause or consequence?, Neurosci. Biobehav. Rev., 6, 47, 10.1016/0149-7634(82)90006-9 Steinberg, 1995, Cerebellar blood flow in schizophrenic patients and normal control subjects, Psych. Res., 61, 15, 10.1016/0925-4927(95)02574-H P.L. Strick, J.P. Card, Transneuronal mapping of neural circuits with alpha herpesviruses, in: J.P. Bolam (Ed.), Experimental Neuroanatomy: A Practical Approach, Oxford University Press, Oxford, 1992, pp. 81–101. P.L. Strick, R.P. Dum, H. Mushiake, Basal ganglia 'loops' with the cerebral cortex, in: M. Kimura, A.M. Graybiel (Eds.), Functions of the cortico-basal ganglia loop, Springer-Verlag, Tokyo, 1995, pp. 106–124. P.L. Strick, J.E. Hoover, H. Mushiake, Evidence for “output channels” in the basal ganglia and cerebellum, in: N. Mano, I. Hamada, M.R. DeLong (Eds.), Role of the Cerebellum and Basal Ganglia in Voluntary Movement, Elsevier, Ameterdam, 1993, pp. 171–180. Strub, 1989, Frontal lobe syndrome in a patient with bilateral globus pallidus lesions, Arch. Neurol., 46, 1024, 10.1001/archneur.1989.00520450096027 Swayze, 1992, Subcortical and temporal structures in affective disorder and schizophrenia: a magnetic resonance imaging study, Biol. Psych., 31, 221, 10.1016/0006-3223(92)90046-3 Swedo, 1989, Cerebral glucose metabolism in childhood-onset obsessive-compulsive disorder, Arch. Gen. Psych., 46, 518, 10.1001/archpsyc.1989.01810060038007 Swerdlow, 1987, Dopamine, schizophrenia, mania, and depression: toward a unified hypothesis of cortico-striato-pallido-thalamic function, Behav. Brain Sci., 10, 197, 10.1017/S0140525X00047488 Tanaka, 1991, Coding visual images of objects in the inferotemporal cortex of the macaque monkey, J. Neurophysiol., 66, 170, 10.1152/jn.1991.66.1.170 Taylor, 1990, Memory and learning in early Parkinson's disease: evidence for a “frontal lobe syndrome”, Brain Cogn., 13, 211, 10.1016/0278-2626(90)90051-O Thach, 1993, Cerebellar nuclei: rapid alternating movement, motor somatotopy, and a mechanisms for the control of muscle synergy, Rev. Neurol. (Paris), 149, 607 Trepanier, 1998, Neuropsychological consequences of posteroventral pallidotomy for the treatment of Parkinson's disease, Neurology, 51, 207, 10.1212/WNL.51.1.207 Trivedi, 1996, Functional neuroanatomy of obsessive-compulsive disorder, J. Clin. Psych., 57, 26 van Kan, 1993, Output organization of intermediate cerebellum of the monkey, J. Neurophysiol., 69, 57, 10.1152/jn.1993.69.1.57 Volkow, 1992, Low cerebellar metabolism in medicated patients with chronic schizophrenia, Am. J. Psych., 149, 686, 10.1176/ajp.149.5.686 vonSattel, 1985, Neuropathological classification of Huntington's disease, J. Neuropathol. Exp. Neurol., 44, 559, 10.1097/00005072-198511000-00003 Walker, 1940, A cytoarchitectural study of the prefrontal area of the macaque monkey, J. Comp. Neurol., 73, 59, 10.1002/cne.900730106 Walker, 1994, Developmentally moderated expressions of the neuropathology underlying schizophrenia, Schiz. Bull., 20, 453, 10.1093/schbul/20.3.453 Weinberger, 1979, Cerebellar atrophy in chronic schizophrenia, Lancet, 1, 718, 10.1016/S0140-6736(79)91164-4 Wetts, 1985, Cerebellar nuclear activity during contraction and reciprocal inhibition of forearm muscles, J. Neurophysiol., 54, 231, 10.1152/jn.1985.54.2.231 Wiesendanger, 1985, Cerebello-cortical linkage in the monkey as revealed by transcellular labeling with the lectin wheat germ agglutinin conjugated to the marker horseradish peroxidase, Exp. Brain Res., 59, 105, 10.1007/BF00237671 Wilson, 1994, Dissociation of object and spatial processing domains in primate prefrontal cortex, Science, 260, 1995 Wilson, 1912, Progressive lenticular degeneration, Brain, 34, 295, 10.1093/brain/34.4.295 S.P. Wise, J.L. Rapoport, Obsessive-compulsive disorder: is it basal ganglia dysfunction, in: J.L. Rapoport (Ed.), Obsessive compulsive disorder in children and adolescents, American Psychiatric Press, Washington, D.C., 1992, pp. 327–344. Wolf, 1996, Tourette syndrome: prediction of phenotypic variation in monozygotic twins by caudate nucleus D2 receptor binding, Science, 273, 1225, 10.1126/science.273.5279.1225 Yamamoto, 1992, The medial dorsal nucleus is one of the thalamic relays of the cerebellocerebral response to the frontal association cortex in the monkey: horseradish peroxidase and fluorescent dye double staining study, Brain Res., 579, 315, 10.1016/0006-8993(92)90067-J Yates, 1987, Cerebellar atrophy in schizophrenia and affective disorder, Am. J. Psych., 144, 465, 10.1176/ajp.144.4.465 Yoshida, 1993, The distribution of the globus pallidus neurons with input from various cortical areas in the monkeys, Brain Res., 611, 170, 10.1016/0006-8993(93)91791-P Zemanick, 1991, Transneuronal transport of herpes simplex virus type 1 in the primate motor system: transport direction is strain dependent, Proc. Natl. Acad. Sci. USA, 88, 8048, 10.1073/pnas.88.18.8048