Potent Neutralizing Antibodies against SARS-CoV-2 Identified by High-Throughput Single-Cell Sequencing of Convalescent Patients’ B Cells

Cell - Tập 182 - Trang 73-84.e16 - 2020
Yunlong Cao1, Bin Su2, Xianghua Guo2, Wenjie Sun1, Yongqiang Deng3, Linlin Bao4, Qinyu Zhu5,6, Xu Zhang7, Yinghui Zheng1, Chenyang Geng1, Xiaoran Chai1, Runsheng He1, Xiaofeng Li3, Qi Lv4, Hua Zhu4, Wei Deng4, Yanfeng Xu4, Yanjun Wang2, Luxin Qiao2, Yafang Tan3
1Beijing Advanced Innovation Center for Genomics (ICG) & Biomedical Pioneering Innovation Center (BIOPIC), Peking University, Beijing 100871, China
2Beijing Youan Hospital, Capital Medical University, Beijing 100069, China
3State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Academy of Military Medical Sciences, Beijing, 100071, China
4Key Laboratory of Human Disease Comparative Medicine, Chinese Ministry of Health, Beijing Key Laboratory for Animal Models of Emerging and Remerging Infectious Diseases, Institute of Laboratory Animal Science, Chinese Academy of Medical Sciences and Comparative Medicine Center, Peking Union Medical College, Beijing, China
5State Key Laboratory of Protein and Plant Gene Research, School of Life Sciences, Peking University, Beijing, China
6Peking-Tsinghua Center for Life Sciences (CLS), Academy for Advanced Interdisciplinary Studies, Peking University, Beijing 100871, China
7Singlomics (Beijing DanXu Pharmaceuticals), Beijing 102206, China

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