Evaluation of Lavandula stoechas L. subsp. stoechas L., Mentha spicata L. subsp. spicata L. essential oils and their main components against sinusitis pathogens

Zeitschrift fur Naturforschung - Section C Journal of Biosciences - Tập 73 Số 9-10 - Trang 353-360 - 2018
Nursenem Karaca1, Betül Demırcı2, Fati̇h Demi̇rci̇3
1Department of Pharmacognosy , Graduate School of Health Sciences , Anadolu University , Eskişehir , Turkey
2Department of Pharmacognosy, Faculty of Pharmacy, Anadolu University, Eskişehir, Turkey
3Department of Pharmacognosy , Faculty of Pharmacy , Anadolu University , 26470-Eskişehir , Turkey , Phone: +90 (222) 335 05 80 – ext. 3711, Fax: +90 (222) 335 07 50, E-mail:

Tóm tắt

Abstract Lavandula stoechas subsp. stoechas and Mentha spicata subsp. spicata are used for the treatment of sinusitis in Turkish folk medicine. The components of essential oils obtained by hydrodistillation were determined by gas chromatography-flame ionization detector (GC-FID), gas chromatography/mass spectrometry (GC/MS), and thin layer chromatography (TLC). Major components of L. stoechas and M. spicata oils were determined as camphor (46.7%) and carvone (60.6%), respectively. The antibacterial activity of essential oils and their main components were tested against the common selected sinusitis pathogens Streptococcus pneumoniae, Streptococcus pyogenes, Staphylococcus aureus, Haemophilus influenzae, Moraxella catarrhalis, and Pseudomonas aeruginosa using in vitro agar diffusion, microdilution, and vapor diffusion methods. As a result, the tested plant materials, which are locally and natively used against sinusitis, were relatively mild antibacterial (in vitro MICs 310–1250 μg/mL) in action. To use essential oils and their components safely in sinusitis therapy, further detailed in vivo experiments are needed to support their efficacy.

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