Cyp2c70 is responsible for the species difference in bile acid metabolism between mice and humans
Tài liệu tham khảo
Russell, 2003, The enzymes, regulation, and genetics of bile acid synthesis, Annu. Rev. Biochem., 72, 137, 10.1146/annurev.biochem.72.121801.161712
Hofmann, 2009, The enterohepatic circulation of bile acids in mammals: form and functions, Front. Biosci. (Landmark Ed.)., 14, 2584, 10.2741/3399
Matsubara, 2013, FXR signaling in the enterohepatic system, Mol. Cell. Endocrinol., 368, 17, 10.1016/j.mce.2012.05.004
Gonzalez, 2012, Nuclear receptor control of enterohepatic circulation, Compr. Physiol., 2, 2811, 10.1002/cphy.c120007
Deo, 2008, Identification of human hepatic cytochrome p450 enzymes involved in the biotransformation of cholic and chenodeoxycholic acid, Drug Metab. Dispos., 36, 1983, 10.1124/dmd.108.022194
Hardison, 1978, Hepatic taurine concentration and dietary taurine as regulators of bile acid conjugation with taurine, Gastroenterology., 75, 71, 10.1016/0016-5085(78)93767-8
Jiang, 2015, Intestinal farnesoid X receptor signaling promotes nonalcoholic fatty liver disease, J. Clin. Invest., 125, 386, 10.1172/JCI76738
Jiang, 2015, Intestine-selective farnesoid X receptor inhibition improves obesity-related metabolic dysfunction, Nat. Commun., 6, 10166, 10.1038/ncomms10166
Li, 2013, Microbiome remodelling leads to inhibition of intestinal farnesoid X receptor signalling and decreased obesity, Nat. Commun., 4, 2384, 10.1038/ncomms3384
Russell, 1992, Bile acid biosynthesis, Biochemistry., 31, 4737, 10.1021/bi00135a001
Inagaki, 2005, Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis, Cell Metab., 2, 217, 10.1016/j.cmet.2005.09.001
Nelson, 2004, Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants, Pharmacogenetics., 14, 1, 10.1097/00008571-200401000-00001
Scheer, 2014, Deletion of 30 murine cytochrome p450 genes results in viable mice with compromised drug metabolism, Drug Metab. Dispos., 42, 1022, 10.1124/dmd.114.057885
Cheung, 2008, Humanized mouse lines and their application for prediction of human drug metabolism and toxicological risk assessment, J. Pharmacol. Exp. Ther., 327, 288, 10.1124/jpet.108.141242
Scheer, 2014, Genetically humanized mouse models of drug metabolizing enzymes and transporters and their applications, Xenobiotica., 44, 96, 10.3109/00498254.2013.815831
van Herwaarden, 2007, Knockout of cytochrome P450 3A yields new mouse models for understanding xenobiotic metabolism, J. Clin. Invest., 117, 3583, 10.1172/JCI33435
Hasegawa, 2011, Quantitative prediction of human pregnane X receptor and cytochrome P450 3A4 mediated drug-drug interaction in a novel multiple humanized mouse line, Mol. Pharmacol., 80, 518, 10.1124/mol.111.071845
Scheer, 2012, Modeling human cytochrome P450 2D6 metabolism and drug-drug interaction by a novel panel of knockout and humanized mouse lines, Mol. Pharmacol., 81, 63, 10.1124/mol.111.075192
Dragin, 2007, Generation of ‘humanized’ hCYP1A1_1A2_Cyp1a1/1a2(-/-) mouse line, Biochem. Biophys. Res. Commun., 359, 635, 10.1016/j.bbrc.2007.05.202
Scheer, 2012, Generation and characterization of novel cytochrome P450 Cyp2c gene cluster knockout and CYP2C9 humanized mouse lines, Mol. Pharmacol., 82, 1022, 10.1124/mol.112.080036
Tanaka, 2015, Role of fibroblast growth factor 21 in the early stage of NASH induced by methionine- and choline-deficient diet, Biochim. Biophys. Acta., 1852, 1242, 10.1016/j.bbadis.2015.02.012
Gu, 2003, Liver-specific deletion of the NADPH-cytochrome P450 reductase gene: impact on plasma cholesterol homeostasis and the function and regulation of microsomal cytochrome P450 and heme oxygenase, J. Biol. Chem., 278, 25895, 10.1074/jbc.M303125200
Cheng, 2014, Decreased bile-acid synthesis in livers of hepatocyte-conditional NADPH-cytochrome P450 reductase-null mice results in increased bile acids in serum, J. Pharmacol. Exp. Ther., 351, 105, 10.1124/jpet.114.216796
Fedorowski, 1979, Transformation of chenodeoxycholic acid and ursodeoxycholic acid by human intestinal bacteria, Gastroenterology., 77, 1068, 10.1016/S0016-5085(79)80079-7
Hofmann, 2004, Detoxification of lithocholic acid, a toxic bile acid: relevance to drug hepatotoxicity, Drug Metab. Rev., 36, 703, 10.1081/DMR-200033475
Sayin, 2013, Gut microbiota regulates bile acid metabolism by reducing the levels of tauro-beta-muricholic acid, a naturally occurring FXR antagonist, Cell Metab., 17, 225, 10.1016/j.cmet.2013.01.003
Mueller, 2015, Ursodeoxycholic acid exerts farnesoid X receptor-antagonistic effects on bile acid and lipid metabolism in morbid obesity, J. Hepatol., 62, 1398, 10.1016/j.jhep.2014.12.034
Katagiri, 1992, Tauro-beta-muricholate preserves choleresis and prevents taurocholate-induced cholestasis in colchicine-treated rat liver, Gastroenterology., 102, 1660, 10.1016/0016-5085(92)91727-L
Löfgren, 2009, Regulation of human CYP2C18 and CYP2C19 in transgenic mice: influence of castration, testosterone, and growth hormone, Drug Metab. Dispos., 37, 1505, 10.1124/dmd.109.026963
Greathouse, 2015, Dysfunctional families: Clostridium scindens and secondary bile acids inhibit the growth of Clostridium difficile, Cell Metab., 21, 9, 10.1016/j.cmet.2014.12.016
Buffie, 2015, Precision microbiome reconstitution restores bile acid mediated resistance to Clostridium difficile, Nature., 517, 205, 10.1038/nature13828
Hirano, 1981, Epimerization of the 7-hydroxy group of bile acids by the combination of two kinds of microorganisms with 7 alpha- and 7 beta-hydroxysteroid dehydrogenase activity, respectively, J. Lipid Res., 22, 1060, 10.1016/S0022-2275(20)40663-7
de Aguiar Vallim, 2015, MAFG is a transcriptional repressor of bile acid synthesis and metabolism, Cell Metab., 21, 298, 10.1016/j.cmet.2015.01.007
Seeley, 2015, The role of gut adaptation in the potent effects of multiple bariatric surgeries on obesity and diabetes, Cell Metab., 21, 369, 10.1016/j.cmet.2015.01.001
Jones, 2015, Impact of physiological levels of chenodeoxycholic acid supplementation on intestinal and hepatic bile acid and cholesterol metabolism in Cyp7a1-deficient mice, Steroids., 93, 87, 10.1016/j.steroids.2014.11.002
Thomas, 2009, TGR5-mediated bile acid sensing controls glucose homeostasis, Cell Metab., 10, 167, 10.1016/j.cmet.2009.08.001
Botham, 1983, The metabolism of chenodeoxycholic acid to beta-muricholic acid in rat liver, Eur. J. Biochem., 134, 191, 10.1111/j.1432-1033.1983.tb07550.x