Poly(ADP-ribose) polymerase: Structure-function relationship

Althaus, 1987, ADP-ribosylation of proteins. Enzymology and biological significance, Mol Biol Biochem Biophys, 37, 1 Lautier, 1993, Molecular and biochemical features of poly(ADP-ribose) metabolism, Mol Cell Biochem, 122, 171, 10.1007/BF01076101 Le Cam, 1994, Conformational analysis of a 139 base-pairs DNA fragment containing a single-stranded break, and its interaction with human poly(ADP-ribose) polymerase, J Mol Biol, 235, 1062, 10.1006/jmbi.1994.1057 Ménissier-de Murcia, 1989, Zinc binding domain of poly(ADP-ribose) polymerase participates in the recognition of single strand breaks on DNA, J Mol Biol, 210, 229, 10.1016/0022-2836(89)90302-1 Gradwohl, 1990, The second zinc-finger domain of poly(ADP-ribose) polymerase determines specificity for single-stranded breaks in DNA, 87, 2990 Schreiber, 1992, The human poly(ADP-ribose) polymerase nuclear localization signal is a bipartite element functionally separate from DNA binding and catalytic activity, EMBO J, 11, 3263, 10.1002/j.1460-2075.1992.tb05404.x Simonin, 1990, Expression and site-directed mutagenesis of the catalytic domain of human poly(ADP-ribose) polymerase in Escherichia coli, J Biol Chem, 265, 19249, 10.1016/S0021-9258(17)30651-8 de Murcia, 1994, Poly (ADP-ribose) polymerase: a molecular nick-sensor, TIBS, 19, 172 Shall, 1984, ADP-ribose in DNA repair: a new component of DNA excision repair, Adv Rad Biol, 11, 1, 10.1016/B978-0-12-035411-5.50007-1 Chatterjee, 1989, Mutants cells defective in poly(ADP-ribose) synthesis due to stable alterations in enzyme activity or substrate availability, Exp Cell Res, 184, 1, 10.1016/0014-4827(89)90358-3 Ding, 1992, Depletion of poly(ADP-ribose) polymerase by antisense RNA expression results in a delay in DNA strand break rejoining, J Biol Chem, 267, 12804, 10.1016/S0021-9258(18)42347-2 Satoh, 1992, Role of poly(ADP-ribose) formation in DNA repair, Nature, 356, 356, 10.1038/356356a0 Satoh, 1993, NAD-dependent repair of damaged DNA by human cell extracts, J Biol Chem, 268, 5480, 10.1016/S0021-9258(18)53346-9 Küpper, 1990, Inhibition of poly(ADP-ribosyl)ation by overexpressing the poly(ADP-ribose) polymerase DNA-binding domain, J Biol Chem, 265, 8721, 10.1016/S0021-9258(17)30567-7 Molinete, 1993, Overproduction of the poly(ADP-ribose) polymerase DNA-binding domain blocks alkylation-induced DNA repair synthesis in mammalian cells, EMBO J, 5, 2109, 10.1002/j.1460-2075.1993.tb05859.x Simonin, 1993, The carboxy-terminal domain of human poly(ADP-ribose) polymerase: overproduction in Escherichia coli, large scale purification and characterization, J Biol Chem, 268, 13454, 10.1016/S0021-9258(19)38671-5 Simonin, 1993, Identification of potential active-site residues in the human poly(ADP-ribose) polymerase, J Biol Chem, 268, 8529, 10.1016/S0021-9258(18)52907-0 Eckert, 1991, DNA polymerase fidelity and the polymerase chain reaction, 1, 17 Simonin, 1991, Detection of poly(ADP-ribose) polymerase activity in crude extracts of higher and lower eukaryotes by activity-blot, Anal Biochem, 195, 226, 10.1016/0003-2697(91)90321-J Marsischky, 1992, Directed mutagenesis of glutamic acid 988 of poly(ADP-ribose) polymerase, 47 Luckow, 1989, Signals important for high level expression of foreign genes in Autographa californica nuclear polyhedrosis virus expression vectors, Virology, 170, 31, 10.1016/0042-6822(89)90348-6 Giner, 1992, Overproduction and large scale purification of the human poly(ADP-ribose) polymerase using a baculovirus expression system, Gene, 114, 279, 10.1016/0378-1119(92)90588-G Jung, 1994, Crystallization and X-ray crystallographic analysis of combinant chicken poly(ADP-ribose) polymerase catalytic domain produced in Sf9 insect cells, J Mol Biol, 244, 114, 10.1006/jmbi.1994.1709 de Murcia, 1983, Poly(ADP-ribose) polymerase automodification and interaction with DNA: electronmicroscopic visualization, EMBO J, 2, 543, 10.1002/j.1460-2075.1983.tb01460.x Ferro, 1983, Poly(ADP-ribosylation) of a DNA topoisomerase I from Calf thymus, J Biol Chem, 258, 6000, 10.1016/S0021-9258(18)32361-5 Kasid, 1989, Poly(ADP-ribose) mediated post-translational modification of chromatin-associated human topoisomerase 1, J Biol Chem, 264, 18687, 10.1016/S0021-9258(18)51522-2 Boothman, 1994, Down-regulation of topoisomerase I in mammalian cells following ionizing radiation, Cancer Res, 54, 4618 Simbulan, 1993, Poly(ADP-ribose) polymerase stimulates DNA polymerase α by physical association, J Biol Chem, 268, 93, 10.1016/S0021-9258(18)54119-3 Eki, 1991, Influence of poly(ADP-ribose) polymerase on the enzymatic synthesis of SV 40 DNA, J Biol Chem, 266, 3087, 10.1016/S0021-9258(18)49958-9 Baksi, 1987, In vivo characterization of the poly(ADP-ribosylation) of SV 40 chromatin and large T antigen by immuno-fractionation, Exp Cell Res, 172, 110, 10.1016/0014-4827(87)90098-X Suto, 1991, Inhibitors of poly(ADP-ribose) polymerase: potential chemotherapeutic agents, Drugs Fut, 18, 723 Kameshita, 1984, Poly(ADP-ribose) synthetase. Separation and identification of three proteolytic fragments as the substrate-binding domain, the DNA binding domain, and the automodification domain, J Biol Chem, 259, 4770, 10.1016/S0021-9258(17)42913-9 Schreiber, 1995, A dominant-negative mutant of human poly(ADP-ribose) polymerase affects cell recovery, apoptosis, and chromosomal stability following DNA damage, 92, 4753