3′UTR-HLA-G polymorphisms and circulating sHLA-G are associated with breast cancer: Evidence from a meta-analysis

Sung, 2021, Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries, CA Cancer J. Clin., 10.3322/caac.21660 Turashvili, 2005, Differentiation of tumours of ductal and lobular origin: II. Genomics of invasive ductal and lobular breast carcinomas, Biomed. Pap. Med. Fac. Univ. Palacky Olomouc Czech Repub., 149, 63, 10.5507/bp.2005.006 Elliott, 2011, Human leukocyte antigen G expression in breast cancer: role in immunosuppression, Cancer Biother. Radiopharm., 26, 153, 10.1089/cbr.2010.0924 Bhatelia, 2014, TLRs: linking inflammation and breast cancer, Cell. Signal., 26, 2350, 10.1016/j.cellsig.2014.07.035 Schreiber, 2011, Cancer immunoediting: integrating immunity's roles in cancer suppression and promotion, Science, 331, 1565, 10.1126/science.1203486 Chen, 2010, Upregulation of human leukocyte antigen–G expression and its clinical significance in ductal breast cancer, Hum. Immunol., 71, 892, 10.1016/j.humimm.2010.06.009 He, 2010, HLA-G expression in human breast cancer: implications for diagnosis and prognosis, and effect on allocytotoxic lymphocyte response after hormone treatment in vitro, Ann. Surg. Oncol., 17, 1459, 10.1245/s10434-009-0891-9 Zhang, 2018, Human leukocyte antigen-G expression and polymorphisms promote cancer development and guide cancer diagnosis/treatment, Oncol. Lett., 15, 699 Donadi, 2011, Implications of the polymorphism of HLA-G on its function, regulation, evolution and disease association, cellular and molecular life sciences, CMLS, 68, 369, 10.1007/s00018-010-0580-7 Loustau, 2013, HLA-G 2012 conference: the 15-year milestone update, Tissue Antigens, 81, 127, 10.1111/tan.12053 Castelli, 2010, The genetic structure of 3′untranslated region of the HLA-G gene: polymorphisms and haplotypes, Genes Immun., 11, 134, 10.1038/gene.2009.74 Hviid, 2003, HLA-G allelic variants are associated with differences in the HLA-G mRNA isoform profile and HLA-G mRNA levels, Immunogenetics, 55, 63, 10.1007/s00251-003-0547-z Rousseau, 2003, The 14 bp Deletion-Insertion polymorphism in the 3′ UT region of the HLA-G gene influences HLA-G mRNA stability, Hum. Immunol., 64, 1005, 10.1016/j.humimm.2003.08.347 Lin, 2018, Heterogeneity of HLA-G expression in cancers: facing the challenges, Front. Immunol., 9 Alegre, 2014, Some basic aspects of HLA-G biology, J. Immunol. Res., 2014, 10.1155/2014/657625 Bukur, 2012, The role of classical and non-classical HLA class I antigens in human tumors, Semin. Cancer Biol., 22, 350, 10.1016/j.semcancer.2012.03.003 Moher, 2009, Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement, PLoS Med., 6, 10.1371/journal.pmed.1000097 Hozo, 2005, Estimating the mean and variance from the median, range, and the size of a sample, BMC Med. Res. Methodol., 5, 13, 10.1186/1471-2288-5-13 Higgins, 2019 Borenstein, 2009 Anzures-Cabrera, 2010, Graphical displays for meta-analysis: an overview with suggestions for practice, Res. Synth. Methods, 1, 66, 10.1002/jrsm.6 Cleophas, 2009, Meta-analysis, basic approach, 263 Egger, 1997, Meta-analysis: principles and procedures, BMJ, 315, 1533, 10.1136/bmj.315.7121.1533 DerSimonian, 2015, Meta-analysis in clinical trials revisited, Contemp. Clin. Trials, 45, 139, 10.1016/j.cct.2015.09.002 Haghi, 2021, Certain haplotypes of the 3′-UTR region of the HLA-G gene are linked to breast cancer, Br. J. Biomed. Sci., 78, 87, 10.1080/09674845.2020.1856495 Adolf, 2019, Implication of soluble HLA-G and HLA-G +3142G/C polymorphism in breast cancer patients receiving adjuvant therapy in Tanzania, Asian Pac. J. Cancer Prev., 20, 3465, 10.31557/APJCP.2019.20.11.3465 Kadiam, 2020, Association of HLA-G 3′UTR 14-bp Ins/Del polymorphism with breast cancer among South Indian women, J. Clin. Pathol., 73, 456, 10.1136/jclinpath-2019-205772 Al Omar, 2019, Association of HLA-G 14-base pair insertion/deletion polymorphism with breast cancer in Saudi Arabia, Genet. Mol. Res., 18, GMR18263 Ouni, 2019, The Impact of HLA-G 3′UTR polymorphisms in breast cancer in a Tunisian population, Immunol. Invest., 48, 521, 10.1080/08820139.2019.1569043 Zidi, 2016, Association of HLA-G +3142 C>G polymorphism and breast cancer in Tunisian population, Immunol. Res., 64, 961, 10.1007/s12026-015-8782-6 Haghi, 2015, 14-bp insertion/deletion polymorphism of the HLA-G gene in breast cancer among women from north western Iran, Asian Pac. J. Cancer Prev., 16, 6155, 10.7314/APJCP.2015.16.14.6155 Jeong, 2014, Human leukocyte antigen-G (HLA-G) polymorphism and expression in breast cancer patients, PLoS ONE, 9, e98284, 10.1371/journal.pone.0098284 Ramos, 2014, Analysis of HLA-G gene polymorphism and protein expression in invasive breast ductal carcinoma, Hum. Immunol., 75, 667, 10.1016/j.humimm.2014.04.005 Eskandari-Nasab, 2013, Association between HLA-G 3′UTR 14-bp ins/del polymorphism and susceptibility to breast cancer, Cancer Biomark., 13, 253, 10.3233/CBM-130364 Elyazji, 2016, Assessment of plasma soluble human leukocyte antigen-G as a prognostic marker in post-chemotherapy breast cancer patients in Gaza strip, Turk. J. Immunol., 4, 7, 10.5606/tji.2016.460 König, 2016, The prognostic impact of soluble and vesicular HLA-G and its relationship to circulating tumor cells in neoadjuvant treated breast cancer patients, Hum. Immunol., 77, 791, 10.1016/j.humimm.2016.01.002 Provatopoulou, 2012, Soluble human leukocyte antigen-G expression in patients with ductal and lobular breast malignancy, Anticancer Res., 32, 1021 Sayed, 2010, HLA-G and its relation to proliferation index in detection and monitoring breast cancer patients, Tissue Antigens, 75, 40, 10.1111/j.1399-0039.2009.01393.x Rebmann, 2003, Secretion of sHLA-G molecules in malignancies, Semin Cancer Biol., 13, 371, 10.1016/S1044-579X(03)00028-2 Ge, 2014, Association between human leukocyte antigen-G 14-bp insertion/deletion polymorphism and cancer risk: a meta-analysis and systematic review, Hum. Immunol., 75, 827, 10.1016/j.humimm.2014.06.004 Zhang, 2014, Association between HLA-G 14-bp insertion/deletion polymorphism and cancer risk: a meta-analysis, J. Buon, 19, 567 Jiang, 2019, HLA-G +3142 C>G polymorphism and cancer risk: evidence from a meta-analysis and trial sequential analysis, Medicine (Baltimore), 98, e16067, 10.1097/MD.0000000000016067 Sayad, 2020, A meta-analysis on diagnostic accuracy of serum HLA-G level in breast cancer, Expert Rev. Precision Med. Drug Dev., 5, 109, 10.1080/23808993.2020.1735936 Harrison, 1993, A 14 bp deletion polymorphism in the HLA-G gene, Hum. Mol. Genet., 2, 2200, 10.1093/hmg/2.12.2200-a Hviid, 2006, Polymorphism in the 5′ upstream regulatory and 3′ untranslated regions of the HLA-G gene in relation to soluble HLA-G and IL-10 expression, Hum. Immunol., 67, 53, 10.1016/j.humimm.2005.12.003 Consiglio, 2011, Association of the HLA-G gene +3142C>G polymorphism with systemic lupus erythematosus, Tissue Antigens, 77, 540, 10.1111/j.1399-0039.2011.01635.x Zidi, 2015, Association between sHLA-G and HLA-G 14-bp deletion/insertion polymorphism in Crohn's disease, Int. Immunol., 27, 289, 10.1093/intimm/dxv002 Rizzo, 2012, Role of HLA-G 14 bp deletion/insertion and +3142C>G polymorphisms in the production of sHLA-G molecules in relapsing-remitting multiple sclerosis, Hum. Immunol., 73, 1140, 10.1016/j.humimm.2012.08.005 Rizzo, 2008, HLA-G genotype and HLA-G expression in systemic lupus erythematosus: HLA-G as a putative susceptibility gene in systemic lupus erythematosus, Tissue Antigens, 71, 520, 10.1111/j.1399-0039.2008.01037.x