Glomerular parietal epithelial cells contribute to adult podocyte regeneration in experimental focal segmental glomerulosclerosis

Kidney International - Tập 88 - Trang 999-1012 - 2015
Diana G. Eng1, Maria W. Sunseri1, Natalya V. Kaverina1, Sebastian S. Roeder1, Jeffrey W. Pippin1, Stuart J. Shankland1
1Department of Medicine, Division of Nephrology, University of Washington School of Medicine, Seattle, Washington, USA

Tài liệu tham khảo

Jefferson, 2014, The pathogenesis of focal segmental glomerulosclerosis, Adv Chronic Kidney Dis, 21, 408, 10.1053/j.ackd.2014.05.009 Wharram, 2005, Podocyte depletion causes glomerulosclerosis: diphtheria toxin-induced podocyte depletion in rats expressing human diphtheria toxin receptor transgene, J Am Soc Nephrol, 16, 2941, 10.1681/ASN.2005010055 Matsusaka, 2005, Genetic engineering of glomerular sclerosis in the mouse via control of onset and severity of podocyte- specific injury, J Am Soc Nephrol, 16, 1013, 10.1681/ASN.2004080720 Marshall, 2007, Cell cycle regulatory proteins in podocyte health and disease, Nephron Exp Nephrol, 106, e51, 10.1159/000101793 Appel, 2009, Recruitment of podocytes from glomerular parietal epithelial cells, J Am Soc Nephrol, 20, 333, 10.1681/ASN.2008070795 Grahammer, 2013, Podocyte regeneration: who can become a podocyte?, Am J Pathol, 183, 333, 10.1016/j.ajpath.2013.04.009 Shankland, 2014, The emergence of the glomerular parietal epithelial cell, Nat Rev Nephrol, 10, 158, 10.1038/nrneph.2014.1 Swetha, 2011, Glomerular parietal epithelial cells of adult murine kidney undergo EMT to generate cells with traits of renal progenitors, J Cell Mol Med, 15, 396, 10.1111/j.1582-4934.2009.00937.x Sagrinati, 2006, Isolation and characterization of multipotent progenitor cells from the Bowman’s capsule of adult human kidneys, J Am Soc Nephrol, 17, 2443, 10.1681/ASN.2006010089 Bariety, 2006, Parietal podocytes in normal human glomeruli, J Am Soc Nephrol, 17, 2770, 10.1681/ASN.2006040325 Wanner, 2014, Unraveling the role of podocyte turnover in glomerular aging and injury, J Am Soc Nephrol, 25, 707, 10.1681/ASN.2013050452 Berger, 2014, The regenerative potential of parietal epithelial cells in adult mice, J Am Soc Nephrol, 25, 693, 10.1681/ASN.2013050481 Rizzo, 2013, Nature and mediators of parietal epithelial cell activation in glomerulonephritides of human and rat, Am J Pathol, 183, 1769, 10.1016/j.ajpath.2013.08.008 Ohse, 2010, De novo expression of podocyte proteins in parietal epithelial cells during experimental glomerular disease, Am J Physiol Renal Physiol, 298, F702, 10.1152/ajprenal.00428.2009 Zhang, 2014, ACE-inhibition increases podocyte number in experimental glomerular disease independent of proliferation, J Renin Angiotensin Aldosterone Syst Zhang, 2013, Podocyte repopulation by renal progenitor cells following glucocorticoids treatment in experimental FSGS, Am J Physiol Renal Physiol, 304, F1375, 10.1152/ajprenal.00020.2013 Zhang, 2012, Retinoids augment the expression of podocyte proteins by glomerular parietal epithelial cells in experimental glomerular disease, Nephron Exp Nephrol, 121, e23, 10.1159/000342808 Pichaiwong, 2013, Reversibility of structural and functional damage in a model of advanced diabetic nephropathy, J Am Soc Nephrol, 24, 1088, 10.1681/ASN.2012050445 Sagrinati, 2006, Isolation and characterization of multipotent progenitor cells from the Bowman’s capsule of adult human kidneys, J Am Soc Nephrol, 17, 2443, 10.1681/ASN.2006010089 Ronconi, 2009, Regeneration of glomerular podocytes by human renal progenitors, J Am Soc Nephrol, 20, 322, 10.1681/ASN.2008070709 Kietzmann, 2014, MicroRNA-193a regulates the transdifferentiation of human parietal epithelial cells toward a podocyte phenotype, J Am Soc Nephrol Sakamoto, 2014, The direction and role of phenotypic transition between podocytes and parietal epithelial cells in focal segmental glomerulosclerosis, Am J Physiol Renal Physiol, 306, F98, 10.1152/ajprenal.00228.2013 Hackl, 2013, Tracking the fate of glomerular epithelial cells in vivo using serial multiphoton imaging in new mouse models with fluorescent lineage tags, Nat Med, 19, 1661, 10.1038/nm.3405 Miyazaki, 2014, Mice are unable to endogenously regenerate podocytes during the repair of immunotoxin-induced glomerular injury, Nephrol Dial Transplant, 29, 1005, 10.1093/ndt/gft413 Guhr, 2013, The expression of podocyte-specific proteins in parietal epithelial cells is regulated by protein degradation, Kidney Int, 84, 532, 10.1038/ki.2013.115 Pippin, 2013, Cells of renin lineage are progenitors of podocytes and parietal epithelial cells in experimental glomerular disease, Am J Pathol, 183, 542, 10.1016/j.ajpath.2013.04.024 Pippin, 2014, Cells of renin lineage take on a podocyte phenotype in aging nephropathy, Am J Physiol Renal Physiol, 306, F1198, 10.1152/ajprenal.00699.2013 Smeets, 2009, Tracing the origin of glomerular extracapillary lesions from parietal epithelial cells, J Am Soc Nephrol, 20, 2604, 10.1681/ASN.2009010122 Chang, 2012, Albumin-induced apoptosis of glomerular parietal epithelial cells is modulated by extracellular signalregulated kinase 1/2, Nephrol Dia Transplant, 27, 1330, 10.1093/ndt/gfr483 Fatima, 2012, Parietal epithelial cell activation marker in early recurrence of FSGS in the transplant, Clin J Am Soc Nephrol, 7, 1852, 10.2215/CJN.10571011 Smeets, 2012, Parietal epithelial cells and podocytes in glomerular diseases, Semin Nephrol, 32, 357, 10.1016/j.semnephrol.2012.06.007 Smeets, 2011, Parietal epithelial cells participate in the formation of sclerotic lesions in focal segmental glomerulosclerosis, J Am Soc Nephrol, 22, 1262, 10.1681/ASN.2010090970 Fanni, 2013, CD44 immunoreactivity in the developing human kidney: a marker of renal progenitor stem cells?, Ren Fail, 35, 967, 10.3109/0886022X.2013.808955 Schmits, 1997, CD44 regulates hematopoietic progenitor distribution, granuloma formation, and tumorigenicity, Blood, 90, 2217, 10.1182/blood.V90.6.2217 Sicking, 2012, Subtotal ablation of parietal epithelial cells induces crescent formation, J Am Soc Nephrol, 23, 629, 10.1681/ASN.2011050449 Okamoto, 2013, Prevalence of CD44-positive glomerular parietal epithelial cells reflects podocyte injury in adriamycin nephropathy, Nephron Exp Nephrol, 124, 11, 10.1159/000357356 Marshall, 2011, Role of smooth muscle protein SM22alpha in glomerular epithelial cell injury, Am J Physiol Renal Physiol, 300, F1026, 10.1152/ajprenal.00187.2010 Ruggenenti, 1999, In chronic nephropathies prolonged ACE inhibition can induce remission: dynamics of time-dependent changes in GFR. Investigators of the GISEN Group. Gruppo Italiano Studi Epidemiologici in Nefrologia, J Am Soc Nephrol, 10, 997, 10.1681/ASN.V105997 Macconi, 2009, Podocyte repopulation contributes to regression of glomerular injury induced by ACE inhibition, Am J Pathol, 174, 797, 10.2353/ajpath.2009.080227 Benigni, 2011, Inhibiting angiotensin-converting enzyme promotes renal repair by limiting progenitor cell proliferation and restoring the glomerular architecture, Am J Pathol, 179, 628, 10.1016/j.ajpath.2011.04.003 Romagnani, 2013, Renal progenitors: an evolutionary conserved strategy for kidney regeneration, Nat Rev Nephrol, 9, 137, 10.1038/nrneph.2012.290 Smeets, 2014, Detection of activated parietal epithelial cells on the glomerular tuft distinguishes early focal segmental glomerulosclerosis from minimal change disease, Am J Pathol, 184, 3239, 10.1016/j.ajpath.2014.08.007 Hakroush, 2014, Extensive podocyte loss triggers a rapid parietal epithelial cell response, J Am Soc Nephrol, 25, 927, 10.1681/ASN.2013070687 Schulte, 2014, Origin of parietal podocytes in atubular glomeruli mapped by lineage tracing, J Am Soc Nephrol, 25, 129, 10.1681/ASN.2013040376 Traykova-Brauch, 2008, An efficient and versatile system for acute and chronic modulation of renal tubular function in transgenic mice, Nat Med, 14, 979, 10.1038/nm.1865 Ohse, 2010, De novo expression of podocyte proteins in parietal epithelial cells during experimental glomerular disease, Am J Physiol Renal Physiol, 298, F702, 10.1152/ajprenal.00428.2009 Ohse, 2009, A new function for parietal epithelial cells: a second glomerular barrier, Am J Physiol Renal Physiol, 297, F1566, 10.1152/ajprenal.00214.2009 Marshall, 2010, The CDK-inhibitor p21 is pro-survival in adriamycin(R)-induced podocyte injury, in vitro and in vivo, Am J Physiol Renal Physiol, 298, F1140, 10.1152/ajprenal.00216.2009