Overexpression of LncRNA AFAP1-AS1 predicts poor prognosis and promotes cells proliferation and invasion in gallbladder cancer

Biomedicine & Pharmacotherapy - Tập 84 - Trang 1249-1255 - 2016
Fei Ma1, Shou-Hua Wang2, Qiang Cai2, Ming-Di Zhang2, Yong Yang2, Jun Ding3
1Department of Oncology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200092, China
2Department of General Surgery, Xinhua Hospital, Shanghai Jiao tong University School of Medicine, Shanghai 200000, China
3Department of Biliary and Pancreatic Surgery, Shanghai Shuguang Hospital Affiliated with Shanghai University of T.C.M., Shanghai, 201203, China

Tài liệu tham khảo

Miller, 2008, Gallbladder carcinoma, Eur. J. Surg. Oncol., 34, 306, 10.1016/j.ejso.2007.07.206 Goetze, 2015, Gallbladder carcinoma: prognostic factors and therapeutic options, World J. Gastroenterol., 21, 12211, 10.3748/wjg.v21.i43.12211 Thiery, 2006, Complex networks orchestrate epithelial-mesenchymal transitions, Nat. Rev. Mol. Cell Biol., 7, 131, 10.1038/nrm1835 Thiery, 2009, Epithelial-mesenchymal transitions in development and disease, Cell, 139, 871, 10.1016/j.cell.2009.11.007 Iwatsuki, 2010, Epithelial-mesenchymal transition in cancer development and its clinical significance, Cancer Sci., 101, 293, 10.1111/j.1349-7006.2009.01419.x Higgins, 2007, Hypoxia promotes fibrogenesis in vivo via HIF-1 stimulation of epithelial-to-mesenchymal transition, J. Clin. Investig., 117, 3810 Mitra, 2015, EMT, CTCs and CSCs in tumor relapse and drug-resistance, Oncotarget, 6, 10697, 10.18632/oncotarget.4037 Mercer, 2009, Long non-coding RNAs: insights into functions, Nat. Rev. Genet., 10, 155, 10.1038/nrg2521 Bergmann, 2014, Long non-coding RNAs: modulators of nuclear structure and function, Curr. Opin. Cell Biol., 26, 10, 10.1016/j.ceb.2013.08.005 Ye, 2015, High expression of AFAP1-AS1 is associated with poor survival and short-term recurrence in pancreatic ductal adenocarcinoma, J. Transl. Med., 13, 137, 10.1186/s12967-015-0490-4 Wu, 2013, Hypomethylation of noncoding DNA regions and overexpression of the long noncoding RNA AFAP1-AS1, in Barrett’s esophagus and esophageal adenocarcinoma, Gastroenterology, 144, 956, 10.1053/j.gastro.2013.01.019 Zeng, 2016, AFAP1-AS1, a long noncoding RNA upregulated in lung cancer and promotes invasion and metastasis, Tumour Biol., 37, 729, 10.1007/s13277-015-3860-x Zhang, 2016, Long noncoding RNA AFAP1-AS1 indicates a poor prognosis of hepatocellular carcinoma and promotes cell proliferation and invasion via upregulation of the RhoA/Rac2 signaling, Int. J. Oncol., 48, 1590, 10.3892/ijo.2016.3385 Wang, 2015, Upregulation of H19 indicates a poor prognosis in gallbladder carcinoma and promotes epithelial-mesenchymal transition, Am. J. Cancer Res., 6, 15 Bo, 2015, Upregulated long non-coding RNA AFAP1-AS1 expression is associated with progression and poor prognosis of nasopharyngeal carcinoma, Oncotarget, 6, 20404, 10.18632/oncotarget.4057 Deng, 2015, The up-regulation of long non-coding RNA AFAP1-AS1 is associated with the poor prognosis of NSCLC patients, Biomed. Pharmacother., 75, 8, 10.1016/j.biopha.2015.07.003 Wang, 2016, Overexpression of lncRNA AFAP1-AS1 correlates with poor prognosis and promotes tumorigenesis in colorectal cancer, Biomed. Pharmacother., 81, 152, 10.1016/j.biopha.2016.04.009