Glucose-induced oxidative stress and programmed cell death in diabetic neuropathy

European Journal of Pharmacology - Tập 375 - Trang 217-223 - 1999
Douglas A Greene1,2, Martin J Stevens3,2, Irina Obrosova1,2, Eva L Feldman4,2
1Department of Internal Medicine, University of Michigan, Ann Arbor, MI/USA
2Michigan Diabetes Research and Training Center, University of Michigan, Ann Arbor, MI, USA
3Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA
4Department of Neurology, University of Michigan, Ann Arbor, MI, USA

Tài liệu tham khảo

Amore, 1997, Nonenzymatically glycated albumin (Amadori adducts) enhances nitric oxide synthase activity and gene expression in endothelial cells, Kidney International, 51, 27, 10.1038/ki.1997.4 Apfel, 1998, Recombinant human nerve growth factor in the treatment of diabetic polyneuropathy, Neurology, 51, 695, 10.1212/WNL.51.3.695 Aruoma, 1988, The antioxidant action of taurine, hypotaurine and their metabolic precursors, Biochemical Journal, 256, 251, 10.1042/bj2560251 Baynes, 1991, Role of oxidative stress in the development of complications of diabetes, Diabetes, 40, 405, 10.2337/diabetes.40.4.405 Bierhaus, 1997, Advanced glycation end product (AGE)-mediated induction of tissue factor in cultured endothelial cells is dependent on RAGE, Circulation, 96, 2262, 10.1161/01.CIR.96.7.2262 Brandsch, 1993, Regulation of taurine transport in human colon carcinoma cell lines (HT-29 and Caco-2) by protein kinase C, American Journal of Physiology, 264, G939 Bursell, 1997, Specific retinal diacylglycerol and protein kinase C beta isoform modulation mimics abnormal retinal hemodynamics in diabetic rat, Investigative Ophthalmology and Visual Science, 38, 2711 Cameron, 1993, Potential therapeutic approaches to the treatment or prevention of diabetic neuropathy: Evidence from experimental studies, Diabetic Medicine, 10, 593, 10.1111/j.1464-5491.1993.tb00131.x Cameron, N.E., Cotter, M.A., 1995a. Comparison of the effects of chronic aldose reductase inhibitor and acetyl-l-cysteine treatment on peripheral nerve blood flow and function in anesthetized diabetic rats, Journal of Physiology, 483P, 142P. Cameron, 1995, Neurovascular dysfunction in diabetic rats: potential contribution of autoxidation and free radicals examined using transition metal chelating agents, Journal of Clinical Investigation, 96, 1159, 10.1172/JCI118104 Cameron, 1996, Comparison of the effects of ascorbyl-gamma-linolenic acid and gamma-linolenic acid in the correction of neurovascular deficits in diabetic rats, Diabetologia, 39, 1047, 10.1007/BF00400653 Cameron, 1997, Metabolic and vascular factors in the pathogenesis of diabetic neuropathy, Diabetes, 46, 31S, 10.2337/diab.46.2.S31 Cameron, 1993, Pharmacological manipulation of vascular endothelium function in non-diabetic and streptozotocin-diabetic rats: effects on nerve conduction, hypoxic resistance and endoneurial capillarization, Diabetologia, 36, 516, 10.1007/BF02743267 Cameron, 1993, Anti-oxidant treatment prevents the development of peripheral nerve dysfunction in streptozotocin-diabetic rats, Diabetologia, 36, 299, 10.1007/BF00400231 Cameron, 1994, Anti-oxidant and pro-oxidant effects on nerve conduction velocity, endoneurial blood flow and oxygen tension in non-diabetic and streptozotocin-diabetic rats, Diabetologia, 37, 449, 10.1007/s001250050131 Cameron, 1997, Comparison of the effects of inhibitors of aldose reductase and sorbitol dehydrogenase on neurovascular function, nerve conduction and tissue polyol pathway metabolites in streptozotocin-diabetic rats, Diabetologia, 40, 271, 10.1007/s001250050674 Cameron, 1997, Effects of protein kinase C inhibition on nerve function, blood flow and Na+K+-ATPase defects in diabetic rats, Diabetes, 46, 31A, 10.2337/diab.46.2.S31 Chan, 1995, Transgenic mice and knockout mutants in the study of oxidative stress in brain injury, Journal of Neurotrauma, 12, 815, 10.1089/neu.1995.12.815 Cotter, 1995, Neuroprotective effects of carvedilol in diabetic rats: prevention of defective peripheral nerve perfusion and conduction velocity, Naunyn-Schmiedeberg's Archives of Pharmacology, 351, 630, 10.1007/BF00170163 Cotter, 1995, Effects of natural free radical scavengers on peripheral nerve and neurovascular function in diabetic rats, Diabetologia, 38, 1285, 10.1007/BF00401760 Cutler, 1989, Deferoxamine therapy in high-ferritin diabetes, Diabetes, 38, 1207, 10.2337/diabetes.38.10.1207 1993, The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus, New England Journal of Medicine, 329, 977, 10.1056/NEJM199309303291401 1995, Effect of intensive diabetes treatment on nerve conduction in the Diabetes Control and Complications Trial, Annals of Neurology, 38, 869, 10.1002/ana.410380607 1995, The effect of intensive diabetes therapy on the development and progression of neuropathy, Annals of Internal Medicine, 122, 561, 10.7326/0003-4819-122-8-199504150-00001 Dyck, 1989, Hypoxic neuropathy: does hypoxia play a role in diabetic neuropathy? The 1988 Roberst Wartenberg Lecture, Neurology, 39, 111, 10.1212/WNL.39.1.111 Dyck, 1993, The prevalence by staged severity of various types of diabetic neuropathy, retinopathy, and nephropathy in a population-based cohort: The Rochester Diabetic Neuropathy Study, Neurology, 43, 817, 10.1212/WNL.43.4.817 Ekstrom, 1995, Neurons and glial cells of the mouse sciatic nerve undergo apoptosis after injury in vivo and in vitro, NeuroReport, 6, 1029, 10.1097/00001756-199505090-00020 Elias, 1998, Peripheral neuropathy in transgenic diabetic mice: restoration of C-fiber function with human recombinant nerve growth factor, Diabetes, 47, 1637, 10.2337/diabetes.47.10.1637 Fernyhough, 1995, Altered neurotrophin mRNA levels in peripheral nerve and skeletal muscle of experimentally diabetic rats, Journal of Neurochemistry, 64, 1231, 10.1046/j.1471-4159.1995.64031231.x Fernyhough, 1998, Target tissue production and axonal transport of neurotrophin-3 are reduced in streptozotocin-diabetic rats, Diabetologia, 41, 300, 10.1007/s001250050907 Garrett, 1997, Alpha-lipoic acid corrects neuropeptide deficits in diabetic rats via induction of trophic support, Neuroscience Letters, 222, 191, 10.1016/S0304-3940(97)13383-3 Giardino, 1998, Aminoguanidine inhibits reactive oxygen species formation, lipid peroxidation, and oxidant-induced apoptosis, Diabetes, 47, 1114, 10.2337/diabetes.47.7.1114 Greene, 1993, Aldose reductase inhibitors: an approach to the treatment of diabetic nerve damage, Diabetes/Metabolism Review, 9, 189, 10.1002/dmr.5610090304 Greene, D.A., Arezzo, J.C., Brown, M.B., et al., in press. Zenarestat Study Group: effect of aldose reductase inhibition on nerve conduction and morphometry in diabetic neuropathy, Journal of Neurology. Hermenegildo, 1993, Decreased glutathione peroxidase activity in sciatic nerve of alloxan-induced diabetic mice and its correlation with blood glucose levels, Neurochemical Research, 18, 893, 10.1007/BF00998274 Hohman, 1997, Resistance to increased oxidative stress is decreased in experimental diabetic neuropathy, Journal of the Peripheral Nervous System, 2, 272 Hothersall, 1988, Antioxidant status in an in vitro model for hyperglycemic lens cataract formation: effect of aldose reductase inhibitor statil, Biochemical Medicine and Metabolic Biology, 40, 109, 10.1016/0885-4505(88)90111-9 Hounsom, L., Horrobin, D.R., Tritschler, H., et al., in press. A lipoic acid-gamma linolenic acid conjugate is effective against multiple indices of experimental diabetic neuropathy, Diabetologia. Inoguchi, 1992, Preferential elevation of protein kinase C isoform beta II and diacylglycerol levels in the aorta and heart of diabetic rats: differential reversibility to glycemic control by islet cell transplantation, Proceedings of the National Academy of Science USA, 89, 11059, 10.1073/pnas.89.22.11059 Ishii, 1998, Protein kinase C activation and its role in the development of vascular complication in diabetes mellitus, Journal of Molecular Medicine, 78, 21, 10.1007/s109-1998-8101-y Jackson, 1990, Role of nerve growth factor in oxidant-antioxidant balance and neuronal injury: I. Stimulation of hydrogen peroxide resistance, Journal of Neuroscience Research, 25, 360, 10.1002/jnr.490250313 Jackson, 1990, Role of nerve growth factor in oxidant–antioxidant balance and neuronal injury: II. A conditioning lesion paradigm, Journal of Neuroscience Research, 25, 369, 10.1002/jnr.490250314 Jiang, 1990, Hydrogen peroxide production during experimental protein glycation, FEBS Letters (Federation of European Biochemical Societies Amsterdam), 268, 69, 10.1016/0014-5793(90)80974-N Karasu, 1995, Effects of anti-oxidant treatment on sciatic nerve dysfunction in streptozotocin-diabetic rats: comparison with essential fatty acids, Diabetologia, 38, 129, 10.1007/BF00400086 Karihaloo, 1997, Protein kinase and Ca2+ modulation of myo-inositol transport in cultured retinal pigment epithelial cells, American Journal of Physiology, 273, C671, 10.1152/ajpcell.1997.273.2.C671 Kim, 1991, Diminished specific activity of cytosolic protein kinase C in sciatic nerve of streptozocin-induced diabetic rats and its correction by dietary myo-inositol, Diabetes, 40, 1545, 10.2337/diabetes.40.11.1545 Kowluru, 1998, Abnormalities of retinal metabolism in diabetes or experimental galactosemia: V. Relationship between protein kinase C and ATPases, Diabetes, 47, 464, 10.2337/diabetes.47.3.464 Koya, 1998, Protein kinase C activation and the development of diabetic complications, Diabetes, 47, 859, 10.2337/diabetes.47.6.859 Koya, 1997, Prevention of glomerular dysfunction in diabetic rats by treatment with d-alpha-tocopherol, Journal of the American Society of Nephrology, 8, 426, 10.1681/ASN.V83426 Lai, 1993, Detection of fructose-3-phosphokinase activity in intact mammalian lenses by 31P NMR spectroscopy, Journal of Biological Chemistry, 268, 7763, 10.1016/S0021-9258(18)53023-4 Lai, 1995, Metabolism of fructose-3-phosphate in the diabetic rat lens, Archives of Biochemistry and Biophysics, 318, 191, 10.1006/abbi.1995.1220 Li, 1996, Cholinergic stimulation of AP-1 and NF kappa B transcription factors is differentially sensitive to oxidative stress in SH-SY5Y neuroblastoma: relationship to phosphoinositide hydrolysis, Journal of Neuroscience, 16, 5914, 10.1523/JNEUROSCI.16-19-05914.1996 Li, 1991, Taurine inhibits protein kinase C-catalyzed phosphorylation of specific proteins in a rat cortical P2 fraction, Journal of Neurochemistry, 56, 1747, 10.1111/j.1471-4159.1991.tb02076.x Love, 1996, Nerve function and regeneration in diabetic and galactosemic rats: Antioxidant and metal chelator effects, European Journal of Pharmacology, 31, 433 Low, 1991, Oxygen free radical effects in sciatic nerve in experimental diabetes, Diabetes, 40, 873, 10.2337/diabetes.40.7.873 Low, 1997, The roles of oxidative stress and antioxidant treatment in experimental diabetic neuropathy, Diabetes, 46, 38S, 10.2337/diab.46.2.S38 Low, 1997, Peripheral nerve energy metabolism in experimental diabetic neuropathy, Neuroscience Research Communications, 21, 49, 10.1002/(SICI)1520-6769(199707)21:1<49::AID-NRC207>3.0.CO;2-T Luo, 1998, Dopamine induces apoptosis through an oxidation-involved SAPK/JNK activation pathway, Journal of Biological Chemistry, 273, 3756, 10.1074/jbc.273.6.3756 Magwere, 1997, Primaquine alters antioxidant enzyme profiles in rat liver and kidney, Free Radical Research, 27, 173, 10.3109/10715769709097849 Matsumoto, 1995, Expression of brain-derived neurotrophic factor and p145TrkB affects survival, differentiation, and invasiveness of human neuroblastoma cells, Cancer Research, 55, 1798 Mullarkey, 1990, Free radical generation by early glycation products: a mechanisms for accelerated atherogenesis in diabetes, Biochemical and Biophysical Research Communications, 173, 932, 10.1016/S0006-291X(05)80875-7 Nagamatsu, 1995, Lipoic acid improves nerve blood flow, reduces oxidative stress, and improves distal nerve conduction in experimental diabetic neuropathy, Diabetes Care, 18, 1160, 10.2337/diacare.18.8.1160 Nickander, 1996, Alpha-lipoic acid: antioxidant potency against lipid peroxidation of neural tissues in vitro and implications for diabetic neuropathy, Free Radical Biology and Medicine, 21, 631, 10.1016/0891-5849(96)00172-4 Nistico, 1992, NGF restores decrease in catalase activity and increases superoxide dismutase and glutathione peroxidase activity in the brain of aged rats, Free Radical Biology and Medicine, 12, 177, 10.1016/0891-5849(92)90024-B Obrosova, 1997, Metabolic compensation for diabetes-induced endoneurial hypoxia, Journal of the Peripheral Nervous System, 2, 290 Park, 1998, Multiple pathways of neuronal death induced by DNA-damaging agents, NGF deprivation, and oxidative stress, Journal of Neuroscience, 18, 830, 10.1523/JNEUROSCI.18-03-00830.1998 Pieper, 1997, Activation of nuclear factor-kappaB in cultured endothelial cells by increased glucose concentration: prevention by calphostin C, Journal of Cardiovascular Pharmacology, 30, 528, 10.1097/00005344-199710000-00019 Romero, 1991, Oxygen toxicity in the nervous tissue: comparison of the antioxidant defense of rat brain and sciatic nerve, Neurochemical Research, 16, 157, 10.1007/BF00965704 Russell, J.W., Windebank, A.J., Sullivan, K.A., et al., in press. Neurons undergo apoptosis in animal and cell culture models of diabetes. Schmidt, 1994, Receptor for advanced glycation end products (AGEs) has a central role in vessel wall interactions and gene activation in response to circulating AGE proteins, Proceedings of the National Academy of Science USA, 91, 881, 10.1073/pnas.91.19.8807 Shindo, 1996, Modulation of basal nitric oxide-dependent cyclic-GMP production by ambient glucose, myo-inositol, and protein kinase C in SH-SY5Y human neuroblastoma cells, Journal of Clinical Investigation, 97, 736, 10.1172/JCI118472 Sies, 1997, Oxidative stress: oxidants and antioxidants, Experimental Physiology, 82, 291, 10.1113/expphysiol.1997.sp004024 Stevens, 1993, Osmotically-induced nerve taurine depletion and the compatible osmolyte hypothesis in experimental diabetic neuropathy in the rat, Diabetologia, 36, 608, 10.1007/BF00404069 Stevens, 1994, The linked roles of nitric oxide, aldose reductase and, (Na+, K+)-ATPase in the slowing of nerve conduction in the streptozotocin diabetic rat, Journal of Clinical Investigation, 94, 853, 10.1172/JCI117406 Stevens, 1995, The aetiology of diabetic neuropathy: the combined roles of metabolic and vascular defects, Diabetic Medicine, 12, 566, 10.1111/j.1464-5491.1995.tb00544.x Stevens, M.J., Cao, X., Van Huysen, C., et al., submitted. Selective effects of dl-lipoic acid on nerve conduction, blood flow, energy state, anti-oxidative defense, and osmolyte content in experimental diabetic neuropathy. Tomlinson, 1994, Aldose reductase inhibitors and their potential for the treatment of diabetic complications, Trends in Pharmacological Sciences, 15, 293, 10.1016/0165-6147(94)90010-8 Tomlinson, 1996, Deficient neurotrophic support in the aetiology of diabetic neuropathy, Diabetic Medicine, 13, 679, 10.1002/(SICI)1096-9136(199607)13:7<679::AID-DIA4138>3.0.CO;2-V Tuck, 1984, Endoneurial blood flow and oxygen tension in the sciatic nerves of rats with experimental diabetic neuropathy, Brain, 107, 935, 10.1093/brain/107.3.935 Van, 1994, Enhanced cellular oxidant stress by the interaction of advanced glycation endporducts with their receptors/binding proteins, Journal of Biological Chemistry, 269, 9889, 10.1016/S0021-9258(17)36966-1 Van Dam, 1995, The role of oxidative stress in neuropathy and other diabetic complications, Diabetes/Metabolism Reviews, 11, 181, 10.1002/dmr.5610110303 Varma, 1997, Formation of advanced glycation end (AGE) products in diabetes: prevention by pyruvate and α-ketoglutarate, Molecular and Cellular Biochemistry, 171, 23, 10.1023/A:1006846501081 Ward, 1998, Irreversible inactivation of protein kinase C by glutathione, Journal of Biological Chemistry, 273, 12558, 10.1074/jbc.273.20.12558 Wolf, S.P., 1993. Transition metals and oxidative stress in the complications of diabetes. In: Gries, F.A., Wessels, K. (Eds.), The Role of Anti-Oxidants in Diabetes Mellitus. Verlagsgrupe, Frankfurt am Main, pp. 82–101. Ziegler, 1995, Treatment of symptomatic diabetic peripheral neuropathy with the anti-oxidant-lipoic acid, Diabetologia, 38, 1425, 10.1007/BF00400603