Sporolides A and B: Structurally Unprecedented Halogenated Macrolides from the Marine Actinomycete Salinispora tropica

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Salinispora tropica, strain CNB-392, was isolated in 1989 from marine sediments (−1 m) near Chub Cay, Bahamas. The strain was cultured in 40 × 1 L seawater-based media (filtered seawater, chitosan, kelp powder, menhaden meal, hydro solubles, and starch) and shaken for 10 days at room temperature under aerobic conditions before extraction.

Sporolide, mp 230−233 °C decomposed

Sporolide, 1020 cm-1

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