Reduction of four-and-a-half LIM-protein 2 expression occurs in human left ventricular failure and leads to altered localization and reduced activity of metabolic enzymes

Tarantini, 2003, Aortic valve replacement in severe aortic stenosis with left ventricular dysfunction: determinants of cardiac mortality and ventricular function recovery, Eur J Cardiothorac Surg, 24, 879, 10.1016/S1010-7940(03)00575-X Arimura, 2007, Structural analysis of four and half LIM protein-2 in dilated cardiomyopathy, Biochem Biophys Res Commun, 357, 162, 10.1016/j.bbrc.2007.03.128 Matsumoto, 2005, Functional analysis of titin/connectin N2-B mutations found in cardiomyopathy, J Muscle Res Cell Motil, 26, 367, 10.1007/s10974-005-9018-5 Lange, 2002, Subcellular targeting of metabolic enzymes to titin in heart muscle may be mediated by DRAL/FHL-2, J Cell Sci, 115, 4925, 10.1242/jcs.00181 Wallimann, 1992, Intracellular compartmentation, structure and function of creatine kinase isoenzymes in tissues with high and fluctuating energy demands: the “phosphocreatine circuit” for cellular energy homeostasis, Biochem J, 281, 21, 10.1042/bj2810021 Dzeja, 2000, Failing energetics in failing hearts, Curr Cardiol Rep, 2, 212, 10.1007/s11886-000-0071-9 O'Brien, 1995, Myocardial Ca(2+)- and ATP-cycling imbalances in end-stage dilated and ischemic cardiomyopathies, Cardiovasc Res, 30, 394, 10.1016/S0008-6363(95)00059-3 Saupe, 1998, Impaired cardiac energetics in mice lacking muscle-specific isoenzymes of creatine kinase, Circ Res, 82, 898, 10.1161/01.RES.82.8.898 Depre, 1998, Mechanisms of control of heart glycolysis, Eur J Biochem, 258, 277, 10.1046/j.1432-1327.1998.2580277.x Muller, 2000, FHL2, a novel tissue-specific coactivator of the androgen receptor, EMBO J, 19, 359, 10.1093/emboj/19.3.359 Van Schaftingen, 1982, Hers HG A kinetic study of pyrophosphate: fructose-6-phosphate phosphotransferase from potato tubers. Application to a microassay of fructose 2,6-bisphosphate, Eur J Biochem, 129, 191, 10.1111/j.1432-1033.1982.tb07039.x Bishop, 1971, Single stable reagent for creatine kinase assay, Clin Chem, 17, 548, 10.1093/clinchem/17.6.548 Chu, 2000, Expression patterns of FHL/SLIM family members suggest important functional roles in skeletal muscle and cardiovascular system, Mech Dev, 95, 259, 10.1016/S0925-4773(00)00341-5 Arber, 1997, MLP-deficient mice exhibit a disruption of cardiac cytoarchitectural organization, dilated cardiomyopathy, and heart failure, Cell, 88, 393, 10.1016/S0092-8674(00)81878-4 Pashmforoush, 2001, Adult mice deficient in actinin-associated LIM-domain protein reveal a developmental pathway for right ventricular cardiomyopathy, Nat Med, 7, 591, 10.1038/87920 Radke, 2007, Targeted deletion of titin N2B region leads to diastolic dysfunction and cardiac atrophy, Proc Natl Acad Sci U S A, 104, 3444, 10.1073/pnas.0608543104 Kong, 2001, Cardiac-specific LIM protein FHL2 modifies the hypertrophic response to beta-adrenergic stimulation, Circulation, 103, 2731, 10.1161/01.CIR.103.22.2731 Purcell, 2004, Extracellular signal-regulated kinase 2 interacts with and is negatively regulated by the LIM-only protein FHL2 in cardiomyocytes, Mol Cell Biol, 24, 1081, 10.1128/MCB.24.3.1081-1095.2004 McLoughlin, 2002, The LIM-only protein DRAL/FHL2 interacts with and is a corepressor for the promyelocytic leukemia zinc finger protein, J Biol Chem, 277, 37045, 10.1074/jbc.M203336200 Wojtas, 1997, Flight muscle function in Drosophila requires colocalization of glycolytic enzymes, Mol Biol Cell, 8, 1665, 10.1091/mbc.8.9.1665 Saks, 1996, On the regulation of cellular energetics in health and disease, Mol Cell Biochem, 160-161, 195, 10.1007/BF00240050 Wixler, 2000, The LIM-only protein DRAL/FHL2 binds to the cytoplasmic domain of several alpha and beta integrin chains and is recruited to adhesion complexes, J Biol Chem, 275, 33669, 10.1074/jbc.M002519200 Kupershmidt, 2002, Cardiac-enriched LIM domain protein fhl2 is required to generate I(Ks) in a heterologous system, Cardiovasc Res, 56, 93, 10.1016/S0008-6363(02)00498-4 Nagueh, 2004, Altered titin expression, myocardial stiffness, and left ventricular function in patients with dilated cardiomyopathy, Circulation, 110, 155, 10.1161/01.CIR.0000135591.37759.AF Makarenko, 2004, Passive stiffness changes caused by upregulation of compliant titin isoforms in human dilated cardiomyopathy hearts, Circ Res, 95, 708, 10.1161/01.RES.0000143901.37063.2f Filipeanu, 2004, Regulation of the cell surface expression and function of angiotensin II type 1 receptor by Rab1-mediated endoplasmic reticulum-to-Golgi transport in cardiac myocytes, J Biol Chem, 279, 41077, 10.1074/jbc.M405988200 Vertessy, 1997, Alternative binding of two sequential glycolytic enzymes to microtubules. Molecular studies in the phosphofructokinase/aldolase/microtubule system, J Biol Chem, 272, 25542, 10.1074/jbc.272.41.25542 Parra, 1995, Effects of low-frequency stimulation on soluble and structure-bound activities of hexokinase and phosphofructokinase in rat fast-twitch muscle, Biochim Biophys Acta, 1251, 154, 10.1016/0167-4838(95)00084-8 Srere, 1998, Location-location-location, Trends Biochem Sci, 23, 319, 10.1016/S0968-0004(98)01262-6 Donker, 2007, Impact of acute and enduring volume overload on mechanotransduction and cytoskeletal integrity of canine left ventricular myocardium, Am J Physiol Heart Circ Physiol, 292, H2324, 10.1152/ajpheart.00392.2006