miRiad Roles for the miR-17-92 Cluster in Development and Disease

Chakraborty, 2007, Repeat organization and epigenetic regulation of the DH-Cmu domain of the immunoglobulin heavy-chain gene locus, Mol. Cell, 27, 842, 10.1016/j.molcel.2007.07.010 Cui, 2007, Retroviral insertional activation of the Fli-3 locus in erythroleukemias encoding a cluster of microRNAs that convert Epo-induced differentiation to proliferation, Blood, 110, 2631, 10.1182/blood-2006-10-053850 Dews, 2006, Augmentation of tumor angiogenesis by a Myc-activated microRNA cluster, Nat. Genet., 38, 1060, 10.1038/ng1855 Egle, 2004, Bim is a suppressor of Myc-induced mouse B cell leukemia, Proc. Natl. Acad. Sci. USA, 101, 6164, 10.1073/pnas.0401471101 Fontana, 2007, MicroRNAs 17-5p-20a-106a control monocytopoiesis through AML1 targeting and M-CSF receptor upregulation, Nat. Cell Biol., 9, 775, 10.1038/ncb1613 He, 2005, A microRNA polycistron as a potential human oncogene, Nature, 435, 828, 10.1038/nature03552 Hossain, 2006, Mir-17-5p regulates breast cancer cell proliferation by inhibiting translation of AIB1 mRNA, Mol. Cell. Biol., 26, 8191, 10.1128/MCB.00242-06 Ivanovska, 2008, MicroRNAs in the miR-106b family regulate p21/CDKN1A and promote cell cycle progression, Mol. Cell. Biol., 28, 2167, 10.1128/MCB.01977-07 Koralov, 2008, Dicer ablation affects antibody diversity and cell survival in the B lymphocyte lineage, Cell, 132, 860, 10.1016/j.cell.2008.02.020 Landais, 2007, Oncogenic potential of the miR-106-363 cluster and its implication in human T-cell leukemia, Cancer Res., 67, 5699, 10.1158/0008-5472.CAN-06-4478 Lewis, 2003, Prediction of mammalian microRNA targets, Cell, 115, 787, 10.1016/S0092-8674(03)01018-3 Lu, 2007, Transgenic over-expression of the microRNA miR-17-92 cluster promotes proliferation and inhibits differentiation of lung epithelial progenitor cells, Dev. Biol., 310, 442, 10.1016/j.ydbio.2007.08.007 O'Donnell, 2005, c-Myc-regulated microRNAs modulate E2F1 expression, Nature, 435, 839, 10.1038/nature03677 Ota, 2004, Identification and characterization of a novel gene, C13orf25, as a target for 13q31-q32 amplification in malignant lymphoma, Cancer Res., 64, 3087, 10.1158/0008-5472.CAN-03-3773 Petrocca, 2008, E2F1-regulated microRNAs impair TGFb-dependent cell cycle arrest and apoptosis in gastric cancer, Cancer Cell, 13, 272, 10.1016/j.ccr.2008.02.013 Stefani, 2008, Small non-coding RNAs in animal development, Nat. Rev. Mol. Cell Biol., 9, 219, 10.1038/nrm2347 Sylvestre, 2007, An E2F/miR-20a autoregulatory feedback loop, J. Biol. Chem., 282, 2135, 10.1074/jbc.M608939200 Ventura, 2008, Targeted deletion reveals essential and overlapping functions of the miR-17∼92 family of miRNA clusters, Cell, 132, 875, 10.1016/j.cell.2008.02.019 Volinia, 2006, A microRNA expression signature of human solid tumors defines cancer gene targets, Proc. Natl. Acad. Sci. USA, 103, 2257, 10.1073/pnas.0510565103 Wang, 2006, Activation of an oncogenic microRNA cistron by provirus integration, Proc. Natl. Acad. Sci. USA, 103, 18680, 10.1073/pnas.0609030103 Woods, 2007, Direct regulation of an oncogenic micro-RNA cluster by E2F transcription factors, J. Biol. Chem., 282, 2130, 10.1074/jbc.C600252200 Xiao, 2008, Lymphoproliferative disease and autoimmunity in mice with elevated miR-17-92 expression in lymphocytes, Nat. Immunol., 9, 405, 10.1038/ni1575 Zhang, 2006, microRNAs exhibit high frequency genomic alterations in human cancer, Proc. Natl. Acad. Sci. USA, 103, 9136, 10.1073/pnas.0508889103 Zhu, 2001, E2F1 and E2F2 determine thresholds for antigen-induced T-cell proliferation and suppress tumorigenesis, Mol. Cell. Biol., 21, 8547, 10.1128/MCB.21.24.8547-8564.2001