Adrenergic Function and the Development of Analgesic Tolerance to Morphine

Kihara, 1986, Important role of adrenergic function in the development of analgesic tolerance to morphine in mice, Japan. J. Pharmacol., 42, 419, 10.1254/jjp.42.419 Takagi, 1966, A modification of Haffner’s method for testing analgesics, Japan. J. Pharmacol., 16, 287, 10.1254/jjp.16.287 Kaneto, 1985, Evidence for the dissociation of morphine analgesia, tolerance and dependence, J. Pharm. Pharmacol., 37, 507, 10.1111/j.2042-7158.1985.tb03054.x Kaneto, 1986, Morphine analgesia without development of tolerance in reserpinized mice, Japan. J. Pharmacol., 42, 169, 10.1254/jjp.42.169 Glaubiger, 1977, Elevated beta-adrenergic receptor number after chronic propranolol treatment, Biochem. Biophys. Res. Commun., 78, 720, 10.1016/0006-291X(77)90238-8 Aarons, 1980, Elevation of β-adrenergic receptor density in human lymphocytes after propranolol administration, J. Clin. Invest., 65, 949, 10.1172/JCI109781 Kuschinsky, 1977, Opiate dependence. In Progress in Pharmacology, 1 Moisés, 1987, Changes in cortical β-adrenergic receptor density and neuronal sensitivity to norepinephrine accompany morphine dependence and withdrawal, Brain Res., 400, 110, 10.1016/0006-8993(87)90658-5 Schwartz, 1978, Endorphins and endorphin receptors in striatum: Relationships with dopaminergic neurons, 245 Llorens, 1978, Hypersensitivity to noradrenaline in cortex after chronic morphine: Relevance to tolerance and dependence, Nature, 274, 603, 10.1038/274603a0