FoxJ1 regulates spinal cord development and is required for the maintenance of spinal cord stem cell potential

Alaynick, 2011, SnapShot: spinal cord development, Cell, 146, 10.1016/j.cell.2011.06.038 Anderson, 2014, Heterogeneity of reactive astrocytes, Neurosci. Lett., 565, 23, 10.1016/j.neulet.2013.12.030 Barnabé-Heider, 2010, Origin of new glial cells in intact and injured adult spinal cord, Cell Stem Cell, 7, 470, 10.1016/j.stem.2010.07.014 Bayraktar, 2014, Astrocyte development and heterogeneity, Cold Spring Harb. Perspect. Biol., 7, a020362, 10.1101/cshperspect.a020362 Charron, 2005, Novel brain wiring functions for classical morphogens: a role as graded positional cues in axon guidance, Dev. Camb. Engl., 132, 2251 Choksi, 2014, Systematic discovery of novel ciliary genes through functional genomics in the zebrafish, Dev. Camb. Engl., 141, 3410 Clevidence, 1994, Members of the HNF-3/forkhead family of transcription factors exhibit distinct cellular expression patterns in lung and regulate the surfactant protein B promoter, Dev. Biol., 166, 195, 10.1006/dbio.1994.1307 Deneen, 2006, The transcription factor NFIA controls the onset of gliogenesis in the developing spinal cord, Neuron, 52, 953, 10.1016/j.neuron.2006.11.019 Dessaud, 2008, Pattern formation in the vertebrate neural tube: a sonic hedgehog morphogen-regulated transcriptional network, Dev. Camb. Engl., 135, 2489 Diez del Corral, 2001, Markers in vertebrate neurogenesis, Nat. Rev. Neurosci., 2, 835, 10.1038/35097587 Goulding, 2009, Circuits controlling vertebrate locomotion: moving in a new direction, Nat. Rev. Neurosci., 10, 507, 10.1038/nrn2608 Guérout, 2014, Cell fate control in the developing central nervous system, Exp. Cell Res., 321, 77, 10.1016/j.yexcr.2013.10.003 Hackett, 1995, Genetic mapping of quantitative trait loci for traits with ordinal distributions, Biometrics, 51, 1252, 10.2307/2533257 Helms, 2003, Specification of dorsal spinal cord interneurons, Curr. Opin. Neurobiol., 13, 42, 10.1016/S0959-4388(03)00010-2 Hochstim, 2008, Identification of positionally distinct astrocyte subtypes whose identities are specified by a homeodomain code, Cell, 133, 510, 10.1016/j.cell.2008.02.046 Jacquet, 2011, Specification of a Foxj1-dependent lineage in the forebrain is required for embryonic-to-postnatal transition of neurogenesis in the olfactory bulb, J. Neurosci. J. Soc. Neurosci., 31, 9368, 10.1523/JNEUROSCI.0171-11.2011 Jacquet, 2009, FoxJ1-dependent gene expression is required for differentiation of radial glia into ependymal cells and a subset of astrocytes in the postnatal brain, Dev. Camb. Engl., 136, 4021 La Manno, 2016, Molecular diversity of midbrain development in mouse, human, and stem cells, Cell, 167, 566, 10.1016/j.cell.2016.09.027 Lake, 2016, Neuronal subtypes and diversity revealed by single-nucleus RNA sequencing of the human brain, Science, 352, 1586, 10.1126/science.aaf1204 Li, 2016, Regenerative potential of ependymal cells for spinal cord injuries over time, EBioMedicine, 13, 55, 10.1016/j.ebiom.2016.10.035 Liu, 2007, Selective expression of Bhlhb5 in subsets of early-born interneurons and late-born association neurons in the spinal cord, Dev. Dyn., 236, 829, 10.1002/dvdy.21061 Lu, 2012, Long-distance growth and connectivity of neural stem cells after severe spinal cord injury, Cell, 150, 1264, 10.1016/j.cell.2012.08.020 Meletis, 2008, Spinal cord injury reveals multilineage differentiation of ependymal cells, PLoS Biol., 6, e182, 10.1371/journal.pbio.0060182 Mullen, 1992, NeuN, a neuronal specific nuclear protein in vertebrates, Development, 116, 201, 10.1242/dev.116.1.201 Murphy, 1997, Old age, multiple formations or genetic plasticity? Clonal diversity in the uniparental Caucasian rock lizard, Lacerta dahli, Genetica, 101, 125, 10.1023/A:1018392603062 Muthusamy, 2014, A knock-in Foxj1CreERT2::GFP mouse for recombination in epithelial cells with motile cilia, Genesis, 52, 350, 10.1002/dvg.22753 Ostrowski, 2003, Targeting expression of a transgene to the airway surface epithelium using a ciliated cell-specific promoter, Mol. Ther. J. Am. Soc. Gene Ther., 8, 637, 10.1016/S1525-0016(03)00221-1 Panchision, 2001, Sequential actions of BMP receptors control neural precursor cell production and fate, Genes Dev., 15, 2094, 10.1101/gad.894701 Perrier, 2004, Derivation of midbrain dopamine neurons from human embryonic stem cells, Proc. Natl. Acad. Sci. USA, 101, 12543, 10.1073/pnas.0404700101 Ren, 2017, Ependymal cell contribution to scar formation after spinal cord injury is minimal, local and dependent on direct ependymal injury, Sci. Rep., 7, 41122, 10.1038/srep41122 Rowitch, 2010, Developmental genetics of vertebrate glial-cell specification, Nature, 468, 214, 10.1038/nature09611 Sabelström, 2013, Resident neural stem cells restrict tissue damage and neuronal loss after spinal cord injury in mice, Science, 342, 637, 10.1126/science.1242576 Shimada, 2017, Prdm16 is required for the maintenance of neural stem cells in the postnatal forebrain and their differentiation into ependymal cells, Genes Dev., 31, 1134, 10.1101/gad.291773.116 Simat, 2007, GABAergic synaptogenesis marks the onset of differentiation of basket and stellate cells in mouse cerebellum, Eur. J. Neurosci., 26, 2239, 10.1111/j.1460-9568.2007.05846.x Stubbs, 2008, The forkhead protein Foxj1 specifies node-like cilia in Xenopus and zebrafish embryos, Nat. Genet., 40, 1454, 10.1038/ng.267 Tsai, 2012, Regional astrocyte allocation regulates CNS synaptogenesis and repair, Science, 337, 358, 10.1126/science.1222381 van Praag, 2002, Functional neurogenesis in the adult hippocampus, Nature, 415, 1030, 10.1038/4151030a Yu, 2013, Floor plate-derived sonic hedgehog regulates glial and ependymal cell fates in the developing spinal cord, Dev. Camb. Engl., 140, 1594 Yu, 2008, Foxj1 transcription factors are master regulators of the motile ciliogenic program, Nat. Genet., 40, 1445, 10.1038/ng.263 Zeisel, 2015, Brain structure. Cell types in the mouse cortex and hippocampus revealed by single-Cell RNA-seq, Science, 347, 1138, 10.1126/science.aaa1934 Zheng, 2010, MicroRNAs are essential for the developmental switch from neurogenesis to gliogenesis in the developing spinal cord, J. Neurosci. J. Soc. Neurosci., 30, 8245, 10.1523/JNEUROSCI.1169-10.2010