Crude tea extracts decrease the mutagenic activity of N-methyl-N′-nitro-N-nitrosoguanidine in vitro and in intragastric tract of rats

Ajay K. Jain1, Kayoko Shimoi1, Yoshiyuki Nakamura1, Tsuneo Kada2, Yukihiko Hara3, Ikuyoshi Tomita1
1Laboratory of Health Science, School of Pharmaceutical Sciences, University of Shizuoka, 2-2-1 Oshika, Shizuoka 422 Japan
2Laboratory of Mutagenesis, National Institute of Genetics, 1, 111 Yata, Mishima 411 Japan
3Food Research Laboratories, Mitsui Norin Co. Ltd., 2-1-50 Cha-machi Fujieda 426 Japan

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