LDL bị oxy hóa và glycation ảnh hưởng chọn lọc đến biểu hiện gen và sản xuất protein của chất ức chế metalloproteinase-3 trong tế bào pericyte mao mạch võng mạc của người

Visse R, Nagase H (2003) Matrix metalloproteinases and tissue inhibitors of metalloproteinases: structure, function, and biochemistry. Circ Res 92:827–839 An E, Lu X, Flippin J et al (2006) Secreted proteome profiling in human RPE cell cultures derived from donors with age related macular degeneration and age matched healthy donors. J Proteome Res 5:2599–25610 Plantner JJ, Jiang C, Smine A (1998) Increase in interphotoreceptor matrix gelatinase A (MMP-2) associated with age-related macular degeneration. Exp Eye Res 67:637–645 Weber BH, Vogt G, Pruett RC, Stohr H, Felbor U (1994) Mutations in the tissue inhibitor of metalloproteinases-3 (TIMP3) in patients with Sorsby’s fundus dystrophy. Nat Genet 8:352–356 Grant MB, Caballero S, Tarnuzzer RW et al (1998) Matrix metalloproteinase expression in human retinal microvascular cells. Diabetes 47:1311–1317 Das A, McGuire PG, Eriqat C et al (1999) Human diabetic neovascular membranes contain high levels of urokinase and metalloproteinase enzymes. Invest Ophthalmol Vis Sci 40:809–813 Giebel SJ, Menicucci G, McGuire PG, Das A (2005) Matrix metalloproteinases in early diabetic retinopathy and their role in alteration of the blood-retinal barrier. Lab Invest 85:597–607 Descamps FJ, Martens E, Kangave D et al (2006) The activated form of gelatinase B/matrix metalloproteinase-9 is associated with diabetic vitreous hemorrhage. Exp Eye Res 83:401–407 Lyons TJ, Baynes JW, Patrick JS, Colwell JA, Lopes-Virella MF (1986) Glycosylation of low density lipoprotein in patients with type 1 (insulin-dependent) diabetes: correlations with other parameters of glycaemic control. Diabetologia 29:685–689 Tsai EC, Hirsch IB, Brunzell JD, Chait A (1994) Reduced plasma peroxyl radical trapping capacity and increased susceptibility of LDL to oxidation in poorly controlled IDDM. Diabetes 43:1010–1014 Paniagua JA, Lopez-Miranda J, Perez-Martinez P et al (2005) Oxidized-LDL levels are changed during short-term serum glucose variations and lowered with statin treatment in early type 2 diabetes: a study of endothelial function and microalbuminuria. Diabet Med 22:1647–1656 Chisolm GM, Steinberg D (2000) The oxidative modification hypothesis of atherogenesis: an overview. Free Radic Biol Med 28:1815–1826 Song W, Barth JL, Lu K et al (2005) Effects of modified low-density lipoproteins on human retinal pericyte survival. Ann N Y Acad Sci 1043:1–6 Cusick M, Chew EY, Chan CC, Kruth HS, Murphy RP, Ferris FL III (2003) Histopathology and regression of retinal hard exudates in diabetic retinopathy after reduction of elevated serum lipid levels. Ophthalmology 110:2126–2133 Lyons TJ, Li W, Wells-Knecht MC, Jokl R (1994) Toxicity of mildly modified low-density lipoproteins to cultured retinal capillary endothelial cells and pericytes. Diabetes 43:1090–1095 Song W, Barth JL, Yu Y et al (2005) Effects of oxidized and glycated LDL on gene expression in human retinal capillary pericytes. Invest Ophthalmol Vis Sci 46:2974–2982 Li C, Wong WH (2001) Model-based analysis of oligonucleotide arrays: expression index computation and outlier detection. Proc Natl Acad Sci USA 98:31–36 Jenkins AJ, Velarde V, Klein RL et al (2000) Native and modified LDL activate extracellular signal-regulated kinases in mesangial cells. Diabetes 49:2160–2169 Vranka JA, Johnson E, Zhu X et al (1997) Discrete expression and distribution pattern of TIMP-3 in the human retina and choroid. Curr Eye Res 16:102–110 Greene J, Wang M, Liu YE, Raymond LA, Rosen C, Shi YE (1996) Molecular cloning and characterization of human tissue inhibitor of metalloproteinase 4. J Biol Chem 271:30375–30380 Huang Y, Mironava M, Lopes-Virella MF (1999) Oxidized LDL stimulates matrix metalloproteinase-1 expression in human vascular endothelial cells. Arterioscler Thromb Vasc Biol 19:2640–2647 Game BA, Maldonado A, He L, Huang Y (2005) Pioglitazone inhibits MMP-1 expression in vascular smooth muscle cells through a mitogen-activated protein kinase-independent mechanism. Atherosclerosis 2005 178:249–256 Lyons TJ, Jenkins AJ, Zheng D et al (2004) Diabetic retinopathy and serum lipoprotein subclasses in the DCCT/EDIC cohort. Invest Ophthalmol Vis Sci 45:910–918 Jenkins AJ, Lyons TJ, Zheng D et al (2003) Lipoproteins in the DCCT/EDIC cohort: associations with diabetic nephropathy. Kidney Int 64:817–828 van Leiden HA, Dekker JM, Moll AC et al (2002) Blood pressure, lipids, and obesity are associated with retinopathy: the Hoorn study. Diabetes Care 25:1320–1325 Misra A, Kumar S, Kishore Vikram N, Kumar A (2003) The role of lipids in the development of diabetic microvascular complications: implications for therapy. Am J Cardiovasc Drugs 3:325–338 Chen W, Jump DB, Grant MB, Esselman WJ, Busik JV (2003) Dyslipidemia, but not hyperglycemia, induces inflammatory adhesion molecules in human retinal vascular endothelial cells. Invest Ophthalmol Vis Sci 44:5016–5022 Barile GR, Pachydaki SI, Tari SR et al (2005) The RAGE axis in early diabetic retinopathy. Invest Ophthalmol Vis Sci 46:2916–2924 Lupo G, Anfuso CD, Ragusa N, Strosznajder RP, Walski M, Alberghina M (2001) t-Butyl hydroperoxide and oxidized low density lipoprotein enhance phospholipid hydrolysis in lipopolysaccharide-stimulated retinal pericytes. Biochim Biophys Acta 1531:143–155 Qaum T, Xu Q, Joussen AM et al (2001) VEGF-initiated blood-retinal barrier breakdown in early diabetes. Invest Ophthalmol Vis Sci 42:2408–2413 Smith EB, Staples EM (1982) Plasma protein concentrations in interstitial fluid from human aortas. Proc R Soc Lond B Biol Sci 217:59–75 Fedak PW, Altamentova SM, Weisel RD et al (2002) Matrix remodeling in experimental and human heart failure: a possible regulatory role for TIMP-3. Am J Physiol Heart Circ Physiol 284:H626–H634 Leeson TS (1979) Rat retinal blood vessels. Can J Ophthalmol 14:21–28 Carlson EC (1989) Fenestrated subendothelial basement membranes in human retinal capillaries. Invest Ophthalmol Vis Sci 30:1923–1932 Crocker DL, Murad TM, Geer JC (1970) Role of the pericyte in wound healing. An ultrastructural study. Exp Mol Pathol 13:90–94 Orlidge A, D’Amore PA (1987) Inhibition of capillary endothelial cell growth by pericytes and smooth muscle cells. J Cell Biol 105:1455–1462 Sato Y, Rifkin DB (1989) Inhibition of endothelial cell movement by pericytes and smooth muscle cells: activation of a latent transforming growth factor-beta-like molecule by plasmin during co-culture. J Cell Biol 109:309–315 Watanabe S, Morisaki N, Tezuka M et al (1997) Cultured retinal pericytes stimulate in vitro angiogenesis of endothelial cells through secretion of a fibroblast growth factor-like molecule. Atherosclerosis 130:101–107 Shepro D, Morel NM (1993) Pericyte physiology. FASEB J 7:1031–1038 Hammes HP (2005) Pericytes and the pathogenesis of diabetic retinopathy. Horm Metab Res 37(Suppl 1):39–43 Kuwabara T, Cogan DG (1963) Retinal vascular patterns. VI. Mural cells of the retinal capillaries. Arch Ophthalmol 69:492–502 Robison WG Jr, Nagata M, Tillis TN, Laver N, Kinoshita JH (1989) Aldose reductase and pericyte-endothelial cell contacts in retina and optic nerve. Invest Ophthalmol Vis Sci 30:2293–2299 Saunders WB, Bohnsack BL, Faske JB (2006) Coregulation of vascular tube stabilization by endothelial cell TIMP-2 and pericyte TIMP-3. J Cell Biol 175:179–191 Qi JH, Ebrahem Q, Moore N et al (2003) A novel function for tissue inhibitor of metalloproteinases-3 (TIMP3): inhibition of angiogenesis by blockage of VEGF binding to VEGF receptor-2. Nat Med 9:407–415 Mohammed FF, Smookler DS, Taylor SE et al (2004) Abnormal TNF activity in Timp3−/− mice leads to chronic hepatic inflammation and failure of liver regeneration. Nat Genet 36:969–977 Joussen AM, Poulaki V, Le ML et al (2004) A central role for inflammation in the pathogenesis of diabetic retinopathy. FASEB J 18:1450–1452 Federici M, Hribal ML, Menghini R et al (2005) Timp3 deficiency in insulin receptor-haploinsufficient mice promotes diabetes and vascular inflammation via increased TNF-alpha. J Clin Invest 115:3494–3505 Federici M, Menghini R, Perego L et al (2006) Reduced TIMP3 levels in atherosclerotic plaques from patients affected by altered glucose tolerance. ADA Annual Scientific Sessions Abstracts, 657-P (Abstr) Fabunmi RP, Sukhova GK, Sugiyama S, Libby P (1998) Expression of tissue inhibitor of metalloproteinases-3 in human atheroma and regulation in lesion-associated cells: a potential protective mechanism in plaque stability. Circ Res 83:270–278