Identification of a new locus at 16q12 associated with time to asthma onset
Tài liệu tham khảo
Martinez, 2013, Asthma, Lancet, 382, 1360, 10.1016/S0140-6736(13)61536-6
Radhakrishnan, 2014, Trends in the age of diagnosis of childhood asthma, J Allergy Clin Immunol, 134, 1057, 10.1016/j.jaci.2014.05.012
Wenzel, 2012, Asthma phenotypes: the evolution from clinical to molecular approaches, Nat Med, 18, 716, 10.1038/nm.2678
Siroux, 2011, Identifying adult asthma phenotypes using a clustering approach, Eur Respir J, 38, 310, 10.1183/09031936.00120810
Moore, 2010, Identification of asthma phenotypes using cluster analysis in the Severe Asthma Research Program, Am J Respir Crit Care Med, 181, 315, 10.1164/rccm.200906-0896OC
Szefler, 2014, Asthma across the ages: knowledge gaps in childhood asthma, J Allergy Clin Immunol, 133, 3, 10.1016/j.jaci.2013.10.018
Ober, 2011, The genetics of asthma and allergic disease: a 21st century perspective, Immunol Rev, 242, 10, 10.1111/j.1600-065X.2011.01029.x
Welter, 2014, The NHGRI GWAS Catalog, a curated resource of SNP-trait associations, Nucleic Acids Res, 42, D1001, 10.1093/nar/gkt1229
Siroux, 2014, Genetic heterogeneity of asthma phenotypes identified by a clustering approach, Eur Respir J, 43, 439, 10.1183/09031936.00032713
Bouzigon, 2007, Evidence for a pleiotropic QTL on chromosome 5q13 influencing both time to asthma onset and asthma score in French EGEA families, Hum Genet, 121, 711, 10.1007/s00439-007-0363-x
Forno, 2012, Genome-wide association study of the age of onset of childhood asthma, J Allergy Clin Immunol, 130, 83, 10.1016/j.jaci.2012.03.020
Moffatt, 2007, Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma, Nature, 448, 470, 10.1038/nature06014
Bouzigon, 2008, Effect of 17q21 variants and smoking exposure in early-onset asthma, N Engl J Med, 359, 1985, 10.1056/NEJMoa0806604
Moffatt, 2010, A large-scale, consortium-based genomewide association study of asthma, N Engl J Med, 363, 1211, 10.1056/NEJMoa0906312
Li, 2009, Genotype imputation, Annu Rev Genomics Hum Genet, 10, 387, 10.1146/annurev.genom.9.081307.164242
Williams, 2000, A note on robust variance estimation for cluster-correlated data, Biometrics, 56, 645, 10.1111/j.0006-341X.2000.00645.x
Hao, 2012, Lung eQTLs to help reveal the molecular underpinnings of asthma, PLoS Genet, 8, e1003029, 10.1371/journal.pgen.1003029
Liang, 2013, A cross-platform analysis of 14,177 expression quantitative trait loci derived from lymphoblastoid cell lines, Genome Res, 23, 716, 10.1101/gr.142521.112
Montgomery, 2010, Transcriptome genetics using second generation sequencing in a Caucasian population, Nature, 464, 773, 10.1038/nature08903
Westra, 2013, Systematic identification of trans eQTLs as putative drivers of known disease associations, Nat Genet, 45, 1238, 10.1038/ng.2756
Stranger, 2007, Population genomics of human gene expression, Nat Genet, 39, 1217, 10.1038/ng2142
Veyrieras, 2008, High-resolution mapping of expression-QTLs yields insight into human gene regulation, PLoS Genet, 4, e1000214, 10.1371/journal.pgen.1000214
2013, The Genotype-Tissue Expression (GTEx) project, Nat Genet, 45, 580, 10.1038/ng.2653
Bernstein, 2012, An integrated encyclopedia of DNA elements in the human genome, Nature, 489, 57, 10.1038/nature11247
Ward, 2012, HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants, Nucleic Acids Res, 40, D930, 10.1093/nar/gkr917
Pruim, 2010, LocusZoom: regional visualization of genome-wide association scan results, Bioinformatics, 26, 2336, 10.1093/bioinformatics/btq419
Hindorff, 2009, Potential etiologic and functional implications of genome-wide association loci for human diseases and traits, Proc Natl Acad Sci U S A, 106, 9362, 10.1073/pnas.0903103106
Himes, 2009, Genome-wide association analysis identifies PDE4D as an asthma-susceptibility gene, Am J Hum Genet, 84, 581, 10.1016/j.ajhg.2009.04.006
McGeachie, 2015, CTNNA3 and SEMA3D: Promising loci for asthma exacerbation identified through multiple genome-wide association studies, J Allergy Clin Immunol, 136, 1503, 10.1016/j.jaci.2015.04.039
Li, 2006, Identification of single nucleotide polymorphisms in FOXJ1 and their association with allergic rhinitis, J Hum Genet, 51, 292, 10.1007/s10038-006-0359-8
Kenny, 2012, A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci, PLoS Genet, 8, e1002559, 10.1371/journal.pgen.1002559
2007, Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls, Nature, 447, 661, 10.1038/nature05911
Cleynen, 2014, Genetic and microbial factors modulating the ubiquitin proteasome system in inflammatory bowel disease, Gut, 63, 1265, 10.1136/gutjnl-2012-303205
Zhang, 2011, Identification of two new loci at IL23R and RAB32 that influence susceptibility to leprosy, Nat Genet, 43, 1247, 10.1038/ng.973
Liu, 2015, Discovery of six new susceptibility loci and analysis of pleiotropic effects in leprosy, Nat Genet, 47, 267, 10.1038/ng.3212
Kugathasan, 2008, Loci on 20q13 and 21q22 are associated with pediatric-onset inflammatory bowel disease, Nat Genet, 40, 1211, 10.1038/ng.203
Barrett, 2005, Haploview: analysis and visualization of LD and haplotype maps, Bioinformatics, 21, 263, 10.1093/bioinformatics/bth457
Elding, 2011, Dissecting the genetics of complex inheritance: linkage disequilibrium mapping provides insight into Crohn disease, Am J Hum Genet, 89, 798, 10.1016/j.ajhg.2011.11.006
Li, 2012, Genome-wide association studies of asthma indicate opposite immunopathogenesis direction from autoimmune diseases, J Allergy Clin Immunol, 130, 861, 10.1016/j.jaci.2012.04.041
Sun, 2010, CYLD: a tumor suppressor deubiquitinase regulating NF-kappaB activation and diverse biological processes, Cell Death Differ, 17, 25, 10.1038/cdd.2009.43
Ogura, 2001, Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-kappaB, J Biol Chem, 276, 4812, 10.1074/jbc.M008072200
Poynter, 2004, NF-kappa B activation in airways modulates allergic inflammation but not hyperresponsiveness, J Immunol, 173, 7003, 10.4049/jimmunol.173.11.7003
Kurakula, 2015, Nuclear receptor Nur77 attenuates airway inflammation in mice by suppressing NF-kappaB activity in lung epithelial cells, J Immunol, 195, 1388, 10.4049/jimmunol.1401714
Lin, 2004, Modulation of Th1 activation and inflammation by the NF-kappaB repressor Foxj1, Science, 303, 1017, 10.1126/science.1093889
Lim, 2012, CYLD negatively regulates transforming growth factor-beta-signalling via deubiquitinating Akt, Nat Commun, 3, 771, 10.1038/ncomms1776
Ioannidis, 2009, Validating, augmenting and refining genome-wide association signals, Nat Rev Genet, 10, 318, 10.1038/nrg2544
Pattaro, 2007, Using the age at onset may increase the reliability of longitudinal asthma assessment, J Clin Epidemiol, 60, 704, 10.1016/j.jclinepi.2006.10.010
Toren, 2006, Self-reported asthma was biased in relation to disease severity while reported year of asthma onset was accurate, J Clin Epidemiol, 59, 90, 10.1016/j.jclinepi.2005.03.019
Dijk, 2013, Genetics of onset of asthma, Curr Opin Allergy Clin Immunol, 13, 193, 10.1097/ACI.0b013e32835eb707
Granell, 2013, Examination of the relationship between variation at 17q21 and childhood wheeze phenotypes, J Allergy Clin Immunol, 131, 685, 10.1016/j.jaci.2012.09.021
Savenije, 2014, Association of IL33-IL-1 receptor-like 1 (IL1RL1) pathway polymorphisms with wheezing phenotypes and asthma in childhood, J Allergy Clin Immunol, 134, 170, 10.1016/j.jaci.2013.12.1080
van der Valk, 2014, Fraction of exhaled nitric oxide values in childhood are associated with 17q11.2-q12 and 17q12-q21 variants, J Allergy Clin Immunol, 134, 46, 10.1016/j.jaci.2013.08.053
Bonnelykke, 2014, A genome-wide association study identifies CDHR3 as a susceptibility locus for early childhood asthma with severe exacerbations, Nat Genet, 46, 51, 10.1038/ng.2830
Fuertes, 2015, Associations between the 17q21 region and allergic rhinitis in 5 birth cohorts, J Allergy Clin Immunol, 135, 573, 10.1016/j.jaci.2014.08.016
Ferreira, 2014, Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype, J Allergy Clin Immunol, 133, 1564, 10.1016/j.jaci.2013.10.030
Hinds, 2013, A genome-wide association meta-analysis of self-reported allergy identifies shared and allergy-specific susceptibility loci, Nat Genet, 45, 907, 10.1038/ng.2686
Gudbjartsson, 2009, Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction, Nat Genet, 41, 342, 10.1038/ng.323