Nanomedicine, an emerging therapeutic strategy for oral cancer therapy

Furness S, Glenny A-M, Worthington H V, Pavitt S, Oliver R, Clarkson JE, et al. Interventions for the treatment of oral cavity and oropharyngeal cancer: chemotherapy. In: Furness S, editor. Cochrane Database Syst. Rev., Chichester, UK: John Wiley & Sons, Ltd; 2011, p. CD006386. https://doi.org/10.1002/14651858.CD006386.pub3. Chi, 2015, Oral cavity and oropharyngeal squamous cell carcinoma–an update, CA Cancer J Clin, 65, 401, 10.3322/caac.21293 Hsu, 2014, Combination antiangiogenic therapy and radiation in head and neck cancers, Oral Oncol, 50, 19, 10.1016/j.oraloncology.2013.10.003 Naruse, 2016, Cetuximab for the treatment of locally advanced and recurrent/metastatic oral cancer: an investigation of distant metastasis, Mol Clin Oncol, 10.3892/mco.2016.928 Li, 2016, Cellular uptake and anticancer activity of salvianolic acid B phospholipid complex loaded nanoparticles in head and neck cancer and precancer cells, Colloids Surf B Biointerfaces, 147, 65, 10.1016/j.colsurfb.2016.07.053 Li, 2009, In vitro and clinical studies of gene therapy with recombinant human adenovirus-p53 injection for oral leukoplakia, Clin Cancer Res, 15, 6724, 10.1158/1078-0432.CCR-09-1296 Iriti, 2013, Chemopreventive potential of flavonoids in oral squamous cell carcinoma in human studies, Nutrients, 5, 2564, 10.3390/nu5072564 Sugiura, 2009, VEGF-C and VEGF-D expression is correlated with lymphatic vessel density and lymph node metastasis in oral squamous cell carcinoma: implications for use as a prognostic marker, Int J Oncol, 34, 673, 10.3892/ijo_00000193 Bran, 2009, The platelet-derived growth factor receptor as a target for vascular endothelial growth factor-mediated anti-angiogenetic therapy in head and neck cancer, Int J Oncol, 34, 255 Keren, 2014, Role of EGFR as a prognostic factor for survival in head and neck cancer: a meta-analysis, Tumor Biol, 35, 2285, 10.1007/s13277-013-1303-0 Qiao, 2010, Epithelial-mesenchymal transition in oral squamous cell carcinoma triggered by transforming growth factor-β1 is Snail family-dependent and correlates with matrix metalloproteinase-2 and -9 expressions, Int J Oncol, 37, 663 de Oliveira, 2012, Retinoblastoma and p53 protein expression in pre-malignant oral lesions and oral squamous cell carcinoma, Mol Med Rep, 6, 163 Hasegawa, 2017, Prognosis of oral squamous cell carcinoma patients with level IV/V metastasis: an observational study, J Craniomaxillofac Surg, 45, 145, 10.1016/j.jcms.2016.10.011 Takahashi, 2014, Clinicopathological analysis of 502 patients with oral squamous cell carcinoma with special interest to distant metastasis, Tokai J Exp Clin Med, 39, 178 Irani, 2016, Distant metastasis from oral cancer: a review and molecular biologic aspects, J Int Soc Prev Community Dent, 6, 265, 10.4103/2231-0762.186805 Lau, 2016, Induction chemotherapy for squamous cell carcinomas of the oral cavity: a cumulative meta-analysis, Oral Oncol, 61, 104, 10.1016/j.oraloncology.2016.08.022 Calixto, 2014, Nanotechnology-based drug delivery systems for treatment of oral cancer: a review, Int J Nanomed, 9, 3719, 10.2147/IJN.S61670 de Visscher, 2013, MTHPC-mediated photodynamic therapy of early stage oral squamous cell carcinoma: a comparison to surgical treatment, Ann Surg Oncol, 20, 3076, 10.1245/s10434-013-3006-6 Wang, 2016, Molecular mechanisms of chemoresistance in oral cancer, Chin J Dent Res, 19, 25 Blanco, 2015, Principles of nanoparticle design for overcoming biological barriers to drug delivery, Nat Biotechnol, 33, 941, 10.1038/nbt.3330 Lecaros, 2016, Nanoparticle delivered VEGF-A siRNA enhances photodynamic therapy for head and neck cancer treatment, Mol Ther, 24, 106, 10.1038/mt.2015.169 Chang, 2013, Curcumin-loaded nanoparticles induce apoptotic cell death through regulation of the function of MDR1 and reactive oxygen species in cisplatin-resistant CAR human oral cancer cells, Int J Oncol, 43, 1141, 10.3892/ijo.2013.2050 Wang, 2015, A cell-targeted chemotherapeutic nanomedicine strategy for oral squamous cell carcinoma therapy, J Nanobiotechnol, 13, 63, 10.1186/s12951-015-0116-2 Godin, 2011, Multistage nanovectors: from concept to novel imaging contrast agents and therapeutics, Acc Chem Res, 44, 979, 10.1021/ar200077p Iafisco, 2013, Cell surface receptor targeted biomimetic apatite nanocrystals for cancer therapy, Small, 9, 3834, 10.1002/smll.201202843 Xu, 2016, An injectable nanoparticle generator enhances delivery of cancer therapeutics, Nat Biotechnol, 34, 414, 10.1038/nbt.3506 Lucky, 2016, In vivo biocompatibility, biodistribution and therapeutic efficiency of titania coated upconversion nanoparticles for photodynamic therapy of solid oral cancers, Theranostics, 6, 1844, 10.7150/thno.15088 Virupakshappa, 2012, Applications of nanomedicine in oral cancer, Oral Health Dent Manage, 11, 62 Wu, 2011, Cancer-cell-specific cytotoxicity of non-oxidized iron elements in iron core-gold shell NPs, Nanomed Nanotechnol, Biol Med, 7, 420, 10.1016/j.nano.2011.01.002 Miao, 2014, Antitumor effect of TRAIL on oral squamous cell carcinoma using magnetic nanoparticle-mediated gene expression, Cell Biochem Biophys, 69, 663, 10.1007/s12013-014-9849-z Anselmo, 2016, Nanoparticles in the clinic, Bioeng Transl Med, 1, 10, 10.1002/btm2.10003 Wicki, 2015, Nanomedicine in cancer therapy: challenges, opportunities, and clinical applications, J Control Release, 200, 138, 10.1016/j.jconrel.2014.12.030 Harrington, 2001, Phase II study of pegylated liposomal doxorubicin (Caelyx) as induction chemotherapy for patients with squamous cell cancer of the head and neck, Eur J Cancer, 37, 2015, 10.1016/S0959-8049(01)00216-7 Gharat, 2016, Oral squamous cell carcinoma: current treatment strategies and nanotechnology-based approaches for prevention and therapy, Crit Rev Ther Drug Carrier Syst, 33, 363, 10.1615/CritRevTherDrugCarrierSyst.2016016272 Caponigro, 2000, Phase I study of Caelyx (doxorubicin HCL, pegylated liposomal) in recurrent or metastatic head and neck cancer, Ann Oncol Off J Eur Soc Med Oncol, 11, 339, 10.1023/A:1008319618638 Faivre, 2004, Locoregional effects of pegylated liposomal doxorubicin (Caelyx) in irradiated area: a phase I-II study in patients with recurrent squamous cell carcinoma of the head and neck, Eur J Cancer, 40, 1517, 10.1016/j.ejca.2004.03.018 Prabhakar, 2013, Challenges and key considerations of the enhanced permeability and retention effect for nanomedicine drug delivery in oncology, Cancer Res, 73, 2412, 10.1158/0008-5472.CAN-12-4561 Melancon, 2011, Targeted multifunctional gold-based nanoshells for magnetic resonance-guided laser ablation of head and neck cancer, Biomaterials, 32, 7600, 10.1016/j.biomaterials.2011.06.039 Mi, 2016, Enzyme-responsive multistage vector for drug delivery to tumor tissue, Pharmacol Res, 113, 92, 10.1016/j.phrs.2016.08.024 Mi, 2016, A micro/nano composite for combination treatment of melanoma lung metastasis, Adv Healthc Mater, 5, 936, 10.1002/adhm.201500910 Sulfikkarali, 2013, Chemopreventive efficacy of naringenin-loaded nanoparticles in 7,12-dimethylbenz(a)anthracene induced experimental oral carcinogenesis, Pathol Oncol Res, 19, 287, 10.1007/s12253-012-9581-1 Iriti, 2017, Rutin, a quercetin glycoside, restores chemosensitivity in human breast cancer cells, Phytother Res, 10.1002/ptr.5878 Singh, 2014, Enhancement of phototoxicity of curcumin in human oral cancer cells using silica nanoparticles as delivery vehicle, Lasers Med Sci, 29, 645, 10.1007/s10103-013-1357-7 Lee, 2012, In vitro suppression of oral squamous cell carcinoma growth by ultrasound-mediated delivery of curcumin microemulsions, Int J Nanomed, 7, 941, 10.2147/IJN.S28510 Mazzarino, 2015, Curcumin-loaded chitosan-coated nanoparticles as a new approach for the local treatment of oral cavity cancer, J Nanosci Nanotechnol, 15, 781, 10.1166/jnn.2015.9189 Mognetti, 2006, Animal models in oral cancer research, Oral Oncol, 42, 448, 10.1016/j.oraloncology.2005.07.014 Gavin, 2015, Layered nanoemulsions as mucoadhesive buccal systems for controlled delivery of oral cancer therapeutics, Int J Nanomed, 10, 1569 Zhao, 2011, Salvianolic acid B, a potential chemopreventive agent, for head and neck squamous cell cancer, J Oncol, 2011, 534548, 10.1155/2011/534548 Zhao, 2015, Self-assembling monomeric nucleoside molecular nanoparticles loaded with 5-FU enhancing therapeutic efficacy against oral cancer, ACS Nano, 9, 9638, 10.1021/acsnano.5b04520 Endo, 2013, Tumor-targeted chemotherapy with the nanopolymer-based drug NC-6004 for oral squamous cell carcinoma, Cancer Sci, 104, 369, 10.1111/cas.12079 Koukourakis, 1999, Liposomal doxorubicin and conventionally fractionated radiotherapy in the treatment of locally advanced non-small-cell lung cancer and head and neck cancer, J Clin Oncol, 17, 3512, 10.1200/JCO.1999.17.11.3512 Mohan, 2016, Dual drug loaded nanoliposomal chemotherapy: a promising strategy for treatment of head and neck squamous cell carcinoma, Eur J Pharm Biopharm, 99, 73, 10.1016/j.ejpb.2015.11.017 Abbasi, 2014, Oral and IV dosages of doxorubicin-methotrexate loaded- nanoparticles inhibit progression of oral cancer by down- regulation of matrix Methaloproteinase 2 expression in vivo, Asian Pac J Cancer Prev, 15, 10705, 10.7314/APJCP.2014.15.24.10705 Abbasi, 2014, New formulated "DOX-MTX-loaded nanoparticles" down- regulate HER2 gene expression and improve the clinical outcome in OSCCs model in rat: the effect of IV and oral modalities, Asian Pac J Cancer Prev, 15, 9355, 10.7314/APJCP.2014.15.21.9355 Abbasi, 2014, Novel DOX-MTX nanoparticles improve oral SCC clinical outcome by down regulation of lymph dissemination factor VEGF-C expression in vivo: oral and IV modalities, Asian Pac J Cancer Prev, 15, 6227, 10.7314/APJCP.2014.15.15.6227 Saiyin, 2014, Sequential release of autophagy inhibitor and chemotherapeutic drug with polymeric delivery system for oral squamous cell carcinoma therapy, Mol Pharm, 11, 1662, 10.1021/mp5000423 Jain, 2012, Gold nanoparticles as novel agents for cancer therapy, Br J Radiol, 85, 101, 10.1259/bjr/59448833 Afifi, 2013, Therapeutic efficacy of plasmonic photothermal nanoparticles in hamster buccal pouch carcinoma, Oral Surg Oral Med Oral Pathol Oral Radiol, 115, 743, 10.1016/j.oooo.2012.11.020 Hirsch, 2006, Metal nanoshells, Ann Biomed Eng, 34, 15, 10.1007/s10439-005-9001-8 Wu, 2011, The selective growth inhibition of oral cancer by iron core-gold shell nanoparticles through mitochondria-mediated autophagy, Biomaterials, 32, 4565, 10.1016/j.biomaterials.2011.03.006 Hackenberg, 2012, Antitumor activity of photo-stimulated zinc oxide nanoparticles combined with paclitaxel or cisplatin in HNSCC cell lines, J Photochem Photobiol B Biol, 114, 87, 10.1016/j.jphotobiol.2012.05.014 Lin, 2015, Cupreous complex-loaded chitosan nanoparticles for photothermal therapy and chemotherapy of oral epithelial carcinoma, ACS Appl Mater Interfaces, 7, 20801, 10.1021/acsami.5b05866 Satapathy, 2015, Enhancement of cytotoxicity and inhibition of angiogenesis in oral cancer stem cells by a hybrid nanoparticle of bioactive quinacrine and silver: implication of base excision repair cascade, Mol Pharm, 12, 4011, 10.1021/acs.molpharmaceut.5b00461 Moosavi Nejad, 2016, Acute effects of sono-activated photocatalytic titanium dioxide nanoparticles on oral squamous cell carcinoma, Ultrason Sonochem, 32, 95, 10.1016/j.ultsonch.2016.02.026 Li, 2012, Photodynamic therapy with hyperbranched poly(ether-ester) chlorin(e6) nanoparticles on human tongue carcinoma CAL-27 cells, Photodiag Photodyn Ther, 9, 76, 10.1016/j.pdpdt.2011.08.001 Hattori, 2004, Enhanced in vitro DNA transfection efficiency by novel folate-linked nanoparticles in human prostate cancer and oral cancer, J Control Release, 97, 173, 10.1016/j.jconrel.2004.03.007 Chen, 2015, Nanoparticle delivery of HIF1α siRNA combined with photodynamic therapy as a potential treatment strategy for head-and-neck cancer, Cancer Lett, 359, 65, 10.1016/j.canlet.2014.12.052 Yu, 2008, PEG-PBLG nanoparticle-mediated HSV-TK/GCV gene therapy for oral squamous cell carcinoma, Nanomedicine (Lond), 3, 813, 10.2217/17435889.3.6.813 Bais, 2015, Orthotopic non-metastatic and metastatic oral cancer mouse models, Oral Oncol, 51, 476, 10.1016/j.oraloncology.2015.01.012 Gohulkumar, 2014, Enhanced cytotoxicity and apoptosis-induced anticancer effect of silibinin-loaded nanoparticles in oral carcinoma (KB) cells, Mater Sci Eng C Mater Biol Appl, 41, 274, 10.1016/j.msec.2014.04.056 Noguchi, 2003, Effects of fibroblast growth inhibitor on proliferation and metastasis of oral squamous cell carcinoma, Oral Oncol, 39, 240, 10.1016/S1368-8375(02)00092-1 Kawashiri, 2009, Inhibitory effect of neoadjuvant chemotherapy on metastasis of oral squamous cell carcinoma in a mouse model, Oral Oncol, 45, 794, 10.1016/j.oraloncology.2008.12.003