Inflammation-Induced Anhedonia: Endotoxin Reduces Ventral Striatum Responses to Reward

Miller, 2009, Inflammation and its disconnects: The role of cytokines in the pathophysiology of major depression, Biol Psychiatry, 65, 732, 10.1016/j.biopsych.2008.11.029 Eisenberger, 2009, An fMRI study of cytokine-induced depressed mood and social pain: The role of sex differences, Neuroimage, 47, 881, 10.1016/j.neuroimage.2009.04.040 Reichenberg, 2001, Cytokine-associated emotional and cognitive disturbances in humans, Arch Gen Psychiatry, 58, 445, 10.1001/archpsyc.58.5.445 Wright, 2005, Acute inflammation and negative mood: Mediation by cytokine activation, Brain Behav Immun, 19, 345, 10.1016/j.bbi.2004.10.003 2000, Diagnostic and Statistical Manual of Mental Disorders Dryman, 1991, Affective symptoms associated either the onset of major depression in the community: Findings from the US National Institute of Mental Health Epidemiological Catchment Area Program, Acta Psychiatr Scand, 84, 1, 10.1111/j.1600-0447.1991.tb01410.x De La Garza, 2005, Endotoxin- or proinflammatory cytokine-induced sickness behavior as an animal model of depression: Focus on anhedonia, Neurosci Biobehav Rev, 29, 761, 10.1016/j.neubiorev.2005.03.016 Yirmiya, 1996, Endotoxin produces a depressive-like episode in rats, Brain Res, 711, 163, 10.1016/0006-8993(95)01415-2 Borowski, 1998, Lipopolysaccharide sentral in vivo biogenic amine variations, and anhedonia, Neuroreport, 9, 3797, 10.1097/00001756-199812010-00006 Hart, 1988, Biological basis of the behavior of sick animals, Neurosci Biobehav Rev, 12, 123, 10.1016/S0149-7634(88)80004-6 Dantzer, 2008, From inflammation to sickness and depression: When the immune system subjugates the brain, Nat Rev Neurosci, 9, 46, 10.1038/nrn2297 Nestler, 2006, The mesolimbic dopamine reward circuit in depression, Biol Psychiatry, 59, 1151, 10.1016/j.biopsych.2005.09.018 Ikemoto, 1999, The role of nucleus accumbens dopamine in motivated behavior: A unifying interpretation with special reference to reward-seeking, Brain Res Brain Res Rev, 31, 6, 10.1016/S0165-0173(99)00023-5 Knutson, 2005, Functional magnetic resonance imaging of reward prediction, Curr Opin Neurol, 18, 411, 10.1097/01.wco.0000173463.24758.f6 Schultz, 1992, Neuronal activity in monkey ventral striatum related to the expectation of reward, J Neurosci, 12, 4595, 10.1523/JNEUROSCI.12-12-04595.1992 Knutson, 2001, Anticipation of increasing monetary reward selectivity recruits nucleus accumbens, J Neurosci, 21, 1, 10.1523/JNEUROSCI.21-16-j0002.2001 Knutson, 2001, Dissociation of reward anticipation and outcome with event-related fMRI, Neuroreport, 12, 3683, 10.1097/00001756-200112040-00016 Berridge, 1998, What is the role of dopamine in reward: Hedonic impact, reward learning, or incentive salience?, Brain Res Brain Res Rev, 28, 309, 10.1016/S0165-0173(98)00019-8 Schultz, 2000, Reward processing in primate orbitofrontal cortex and basal ganglia, Cereb Cortex, 10, 272, 10.1093/cercor/10.3.272 Pizzagalli, 2009, Reduced caudate and nucleus accumbens response to rewards in unmediated individuals with major depressive disorder, Am J Psychiatry, 166, 702, 10.1176/appi.ajp.2008.08081201 Wacker, 2009, The role of the nucleus accumbens and rostral anterior cingulated cortex in anhedonia: Integration of resting EEG, fMRI, and volumetric techniques, Neuroimage, 46, 327, 10.1016/j.neuroimage.2009.01.058 Epstein, 2006, Lack of ventral striatal response to positive stimuli in depressed versus non-depressed subjects, Am J Psychiatry, 163, 1784, 10.1176/ajp.2006.163.10.1784 Keedwell, 2005, The neural correlates of anhedonia in major depressive disorder, Biol Psychiatry, 58, 843, 10.1016/j.biopsych.2005.05.019 McCabe, 2009, Neural representation of reward in recovered depressed patients, Psychopharmacology (Berl), 205, 667, 10.1007/s00213-009-1573-9 Suffredini, 1999, Pathophysiological responses to endotoxin in humans, 817 Suffredini, 1999, Dose-related inflammatory effects of intravenous endotoxin in humans: Evaluation of a new clinical lot of Escherichia coli O: 113 endotoxin, J Infect Dis, 179, 1278, 10.1086/314717 First, 1996 McNair, 1971 Maldjian, 2003, An automated method for neuroanatomic and cytoarchitectonic atlas-based interrogation of fMRI datasets, Neuroimage, 19, 1233, 10.1016/S1053-8119(03)00169-1 Tzourio-Mazoyer, 2002, Automated anatomical labeling of the MNI MRI single-subject brain, Neuroimage, 15, 273, 10.1006/nimg.2001.0978 Lieberman, 2009, Type I and type II error concerns in fMRI research: Re-balancing the scale, Soc Cogn Affect Neurosci, 4, 423, 10.1093/scan/nsp052 Kamata, 2000, Effect of single intracerebroventricular injection of α-interferon on monoamine concentrations in the rat brain, Eur Neuropsychopharmacol, 10, 129, 10.1016/S0924-977X(99)00067-X Maurino, 2010, Effect of in vivo striatal perfusion of lipopolysaccharide on dopamine metabolites, Neurosci Lett, 475, 121, 10.1016/j.neulet.2010.03.050 Ressler, 2000, The role of serotonergic and noradrenergic systems in the pathophysiology of depression and anxiety disorders, Depress Anxiety, 12, 2, 10.1002/1520-6394(2000)12:1+<2::AID-DA2>3.0.CO;2-4 Eisenberger, 2010, Inflammation and social experience: An inflammatory challenge induces feelings of social disconnection, Brain Behav Immun, 24, 558, 10.1016/j.bbi.2009.12.009 Harrison, 2009, Inflammation causes mood changes through alterations in subgenual cingulate activity and mesolimbic connectivity, Biol Psychiatry, 66, 407, 10.1016/j.biopsych.2009.03.015