Épidémiologie, histoire naturelle et pathogenèse du carcinome hépatocellulaire

Cancer/Radiothérapie - Tập 9 - Trang 452-457 - 2005
P. Merle1
1Service d'hépatogastroentérologie, hôpital de l'Hôtel-Dieu, Inserm U271, 69003 Lyon, France

Tài liệu tham khảo

Bosch, 2005, Epidemiology of hepatocellular carcinoma, Clin. Liver Dis., 9, 191, 10.1016/j.cld.2004.12.009 Borzio, 1995, Liver cell dysplasia is a major risk for hepatocellular carcinoma in cirrhosis: a prospective study, Gastroenterology, 108, 812, 10.1016/0016-5085(95)90455-7 Cariani, 1988, Differential expression of insulin-like growth factor II mRNA in human primary liver cancers, benign liver tumors, and liver cirrhosis, Cancer Res., 48, 6844 Chisari, 1989, Molecular pathogenesis of hepatocellular carcinoma in hepatitis B virus transgenic mice, Cell, 59, 1145, 10.1016/0092-8674(89)90770-8 de la Coste, 1998, Somatic mutations of the β-catenin gene are frequent in mouse and human hepatocellular carcinoma, Proc. Natl. Acad. Sci. USA, 95, 8847, 10.1073/pnas.95.15.8847 de Souza, 1995, M6P/IGF2R gene is mutated in human hepatocellular carcinomas with loss of heterozygosity, Nat. Genet., 11, 447, 10.1038/ng1295-447 Dejean, 1990, Hepatitis B virus as an insertional mutagene in a human hepatocellular carcinoma, Mol. Biol. Med., 7, 213 Deuffic, 1998, Trends in primary liver cancer, Lancet, 351, 214, 10.1016/S0140-6736(05)78179-4 Deuffic, 1999, Modeling the hepatitis C virus epidemic in France, Hepatology, 29, 1596, 10.1002/hep.510290528 Edamoto, 2003, Alterations of RB1, p53 and Wnt pathways in hepatocellular carcinomas associated with hepatitis C, hepatitis B and alcoholic liver cirrhosis, Int. J. Cancer, 106, 334, 10.1002/ijc.11254 El-Serag, 1999, Rising incidence of hepatocellular carcinoma in the United States, Engl. J. Med., 340, 745, 10.1056/NEJM199903113401001 El-Serag, 2003, The continuing increase in the incidence of hepatocellular carcinoma in the United States: an update, Ann. Intern. Med., 139, 817, 10.7326/0003-4819-139-10-200311180-00009 Finkel, 2000, Oxidants, oxidative stress and the biology of ageing, Nature, 408, 239, 10.1038/35041687 Henmi, 1995, Karyometric analysis of liver cell dysplasia and hepatocellular carcinoma: evidence against precancerous nature of liver cell dysplasia, Cancer, 55, 2594, 10.1002/1097-0142(19850601)55:11<2594::AID-CNCR2820551111>3.0.CO;2-7 Hildt, 1998, The PreS2 activators of the hepatitis B virus: activators of tumour promoter pathways, Recent Results Cancer Res., 154, 315, 10.1007/978-3-642-46870-4_23 Holcombe, 2002, Expression of Wnt ligands and Frizzled receptors in colonic mucosa and in colon carcinoma, Mol. Pathol., 55, 220, 10.1136/mp.55.4.220 Hsu, 1991, Mutational hotspot in the p53 gene in human hepatocellular carcinomas, Nature, 350, 427, 10.1038/350427a0 Ikeda, 1993, A multivariate analysis of risk factors for hepatocellular carcinogenesis: a prospective observation of 795 patients with viral and alcoholic cirrhosis, Hepatology, 18, 47, 10.1002/hep.1840180109 Kim, 1991, HBx gene of hepatitis B virus induces liver cancer in transgenic mice, Nature, 351, 317, 10.1038/351317a0 Kojima, 1997, Telomerase activity and telomere length in hepatocellular carcinoma and chronic liver disease, Gastroenterology, 112, 493, 10.1053/gast.1997.v112.pm9024303 Kuhl, 2000, The Wnt/Ca2+ pathway. A new vertebrate Wnt signalling pathway takes shape, Trends Genet., 16, 279 Laurent-Puig, 2001, Genetic alterations associated with hepatocellular carcinomas define distinct pathways of hepatocarcinogenesis, Gastroenterology, 120, 1763, 10.1053/gast.2001.24798 Law, 2003, Modelling hepatitis C virus incidence, prevalence and long-term sequelae in Australia, 2001, Int. J. Epidemiol., 32, 717, 10.1093/ije/dyg101 Lee, 1997, Large cell change (liver cell dysplasia) and hepatocellular carcinoma in cirrhosis. Matched case-control study, pathological analysis, and pathogenetic hypothesis, Hepatology, 26, 1415, 10.1002/hep.510260607 Lin, 2002, Activation of the JNK signalling pathway: breaking the brake on apoptosis, Bioessays, 25, 17, 10.1002/bies.10204 Llovet, 2003, Hepatocellular carcinoma, Lancet, 362, 1907, 10.1016/S0140-6736(03)14964-1 Lu, 2004, Activation of the Wnt signalling pathway in chronic lymphocytic leukemia, Proc. Natl. Acad. Sci. USA, 101, 3118, 10.1073/pnas.0308648100 Lundberg, 1999, Control of the cell cycle and apoptosis, Eur. J. Cancer, 35, 531, 10.1016/S0959-8049(99)00292-0 Matsubara, 1990, Integration of hepatitis B virus DNA and its implications for hepatocarcinogenesis, Mol. Biol. Med., 7, 243 Merle, 2001, Preliminary results of interferon-alpha therapy on woodchuck hepatitis virus-induced hepatocarcinogenesis: possible benefit in female transgenic mice, J. Hepatol., 34, 562, 10.1016/S0168-8278(00)00054-4 Merle, 2003, Interferon-alpha therapy dose- and time-dependently delays Hepadnavirus-related hepatocarcinogenesis in X/myc transgenic mice, Oncogene, 22, 2762, 10.1038/sj.onc.1206375 Merle, 2004, Functional consequences of Frizzled-7 receptor overexpression in human hepatocellular carcinoma, Gastroenterology, 127, 1110, 10.1053/j.gastro.2004.07.009 Merle, 2005, Oncogenic role of the Frizzled-7/β-catenin pathway in hepatocellular carcinoma, J. Hepatol., 10.1016/j.jhep.2005.05.018 Majumder, 2003, Expression of hepatitis C virus non-structural 5A protein in the liver of transgenic mice, FEBS Lett., 555, 528, 10.1016/S0014-5793(03)01337-1 Montesano, 1997, Hepatocellular carcinoma: from gene to public health, J. Natl. Cancer Inst., 89, 1844, 10.1093/jnci/89.24.1844 Moriya, 1998, The core protein of hepatitis C virus induces hepatocellular carcinoma in transgenic mice, Nat. Med., 4, 1065, 10.1038/2053 Moriya, 2001, Oxidative stress in the absence of inflammation in a mouse model for hepatitis C virus-associated hepatocarcinogenesis, Cancer Res., 61, 4365 Nakamoto, 1998, Immune pathogenesis of hepatocellular carcinoma, J. Exp. Med., 188, 341, 10.1084/jem.188.2.341 Nakanuma, 1993, Adenomatous hyperplasia of the liver as a precancerous lesion, Liver, 13, 1, 10.1111/j.1600-0676.1993.tb00597.x Natarajan, 1997, Large-cell change of hepatocytes in cirrhosis may represent a reaction to prolonged cholestasis, Am. J. Surg. Pathol., 21, 312, 10.1097/00000478-199703000-00007 Parkin, 2001, Estimating the world cancer burden: Globocan 2000, Int. J. Cancer, 94, 153, 10.1002/ijc.1440 Paterlini-Brechot, 2003, Hepatitis B virus-related insertional mutagenesis occurs frequently in human liver cancers and recurrently targets human telomerase gene, Oncogene, 22, 3911, 10.1038/sj.onc.1206492 Qiang, 2003, Wnt signalling in B-cell neoplasia, Oncogene, 22, 1536, 10.1038/sj.onc.1206239 Ray, 1997, Transcriptional repression of p53 promoter by hepatitis C virus core protein, J. Biol. Chem., 272, 10983, 10.1074/jbc.272.17.10983 Ray, 1998, Hepatitis C virus core protein represses p21WAF1/Cip1/Sid1 promoter activity, Gene, 208, 331, 10.1016/S0378-1119(98)00030-4 Shibata, 1998, Irregular regeneration of hepatocytes and risk of hepatocellular carcinoma in chronic hepatitis and cirrhosis with hepatitis-C-virus infection, Lancet, 351, 1773, 10.1016/S0140-6736(97)08002-1 Simon, 1995, Integration of hepatitis B virus and alteration of the 1p36 region found in cancerous tissue of primary hepatocellular carcinoma with viral replication evidenced only in noncancerous, cirrhotic tissue, Hepatology, 22, 1393 Sugitani, 1998, Hyperplastic foci reflect the risk of multicentric development of human hepatocellular carcinoma, J. Hepatol., 28, 1045, 10.1016/S0168-8278(98)80355-3 Suzuki, 2004, Epigenetic inactivation of SFRP genes allows constitutive WNT signalling in colorectal cancer, Nat. Genet., 36, 417, 10.1038/ng1330 Takayama, 1990, Malignant transformation of adenomatous hyperplasia to hepatocellular carcinoma, Lancet, 33, 1150, 10.1016/0140-6736(90)92768-D Tan, 2001, How hepatitis C virus counteracts the interferon response: the jury is still out on NS5A, Virology, 284, 1, 10.1006/viro.2001.0885 Tanaka, 1998, A novel frizzled gene identified in human esophageal carcinoma mediates APC/β-catenin signals, Proc. Natl. Acad. Sci. USA, 95, 10164, 10.1073/pnas.95.17.10164 Theise, 1995, Macroregenerative (dysplastic) nodules and hepatocarcinogenesis, Semin. Liver Dis., 15, 360, 10.1055/s-2007-1007287 Uchida, 1995, Small hepatocellular carcinoma: its relationship to multistep hepatocarcinogenesis, Pathol. Int., 45, 175, 10.1111/j.1440-1827.1995.tb03440.x Wang, 1990, Hepatitis B virus integration in a cyclin A gene in a hepatocellular carcinoma, Nature, 343, 555, 10.1038/343555a0 Wang, 1991, Topoisomerase I-mediated integration of hepadnavirus DNA in vitro, J. Virol., 65, 2381, 10.1128/JVI.65.5.2381-2392.1991 Weeraratna, 2002, Wnt5a signalling directly affects cell motility and invasion of metastatic melanoma, Cancer Cell, 3, 279, 10.1016/S1535-6108(02)00045-4 Weinberg, 1989, Oncogenes, antioncogenes, and the molecular bases of multistep carcinogenesis, Cancer Res., 49, 3713 Wentz, 2000, Dissociation of DDB1-binding and transactivation properties of the hepatitis B virus X protein, Virus Res., 68, 87, 10.1016/S0168-1702(00)00160-X Yeh, 1987, Elevation of transforming growth factor alpha and its relationship to the epidermal growth factor and alpha-fetoprotein levels in patients with hepatocellular carcinoma, Cancer Res., 47, 896 Zhang, 1990, The expression of c-myc and c-N-ras in human cirrhotic livers, hepatocellular carcinomas and liver tissue surrounding the tumors, Oncogene, 5, 909 Zhang, 1994, Deletions of chromosome 13q, mutations in retinoblastoma 1, and retinoblastoma protein state in human hepatocellular carcinoma, Cancer Res., 54, 4177 Zhao, 1994, Immunohistochemical analysis of p53 protein overexpression in liver cell dysplasia and in hepatocellular carcinoma, Virchows Arch., 424, 613, 10.1007/BF01069741