Multicomponent access to novel proline/cyclized cysteine tethered monastrol conjugates as potential anticancer agents
Tài liệu tham khảo
Cioc, 2014, Multicomponent reactions: advanced tools for sustainable organic synthesis, Green Chem., 16, 2958, 10.1039/C4GC00013G
Dömling, 2012, Chemistry and biology of multicomponent reactions, Chem. Rev., 112, 3083, 10.1021/cr100233r
Rotstein, 2014, Small heterocycles in multicomponent reactions, Chem. Rev., 114, 8323, 10.1021/cr400615v
de Fátima, 2015, A mini-review on Biginelli adducts with notable pharmacological properties, J. Adv. Res., 6, 363, 10.1016/j.jare.2014.10.006
Matos, 2018, Biological activity of dihydropyrimidinone (DHPM) derivatives: a systematic review, Eur. J. Med. Chem., 143, 1779, 10.1016/j.ejmech.2017.10.073
Blaskovich, 2016, Unusual amino acids in medicinal chemistry, J. Med. Chem., 59, 10807, 10.1021/acs.jmedchem.6b00319
van Vuuren, 2015, Antimitotic drugs in the treatment of cancer, Cancer Chemother. Pharmacol., 76, 1101, 10.1007/s00280-015-2903-8
Dumontet, 2010, Microtubule-binding agents: a dynamic field of cancer therapeutics, Nat. Rev. Drug Discovery, 9, 790, 10.1038/nrd3253
Canta, 2009, Tubulin: a target for antineoplastic drugs into the cancer cells but also in the peripheral nervous system, Curr. Med. Chem., 16, 1315, 10.2174/092986709787846488
Argyriou, 2008, Peripheral nerve damage associated with administration of taxanes in patients with cancer, Crit. Rev. Oncol./Hematol., 66, 218, 10.1016/j.critrevonc.2008.01.008
Wang, 2014, Multiple mechanisms underlying acquired resistance to taxanes in selected docetaxel-resistant MCF-7 breast cancer cells, BMC Cancer, 14
Huszar, 2009, Kinesin motor proteins as targets for cancer therapy, Cancer Metast. Rev., 28, 197, 10.1007/s10555-009-9185-8
Miki, 2001, All kinesin superfamily protein, KIF, genes in mouse and human, PNAS, 98, 7004, 10.1073/pnas.111145398
Wittmann, 2001, The spindle: a dynamic assembly of microtubules and motors, Nat. Cell Biol., 3, E28, 10.1038/35050669
Blangy, 1995, Phosphorylation by p34cdc2 regulates spindle association of human Eg5, a kinesin-related motor essential for bipolar spindle formation in vivo, Cell, 83, 1159, 10.1016/0092-8674(95)90142-6
Talapatra, 2012, The structure of the ternary Eg5–ADP–ispinesib complex, Acta Crystallogr. D Biol. Crystallogr., 68, 1311, 10.1107/S0907444912027965
Mayer, 1999, Small molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen, Science (New York, N.Y.), 286, 971, 10.1126/science.286.5441.971
DeBonis, 2003, Interaction of the mitotic inhibitor monastrol with human kinesin Eg5, Biochemistry, 42, 338, 10.1021/bi026716j
Yoon, 2005, Monastrol, a selective inhibitor of the mitotic kinesin Eg5, induces a distinctive growth profile of dendrites and axons in primary cortical neuron cultures, Cell Motil. Cytoskelet., 60, 181, 10.1002/cm.20057
Sarli, 2005, Synthesis and biological evaluation of novel EG5 inhibitors, Chembiochem.: a Eur. J. Chem. Biol., 6, 2005, 10.1002/cbic.200500168
DeBonis, 2004, In vitro screening for inhibitors of the human mitotic kinesin Eg5 with antimitotic and antitumor activities, Mol. Cancer Ther., 3, 1079, 10.1158/1535-7163.1079.3.9
Gartner, 2005, Development and biological evaluation of potent and specific inhibitors of mitotic Kinesin Eg5, Chembiochem.: Eur. J. Chem. Biol., 6, 1173, 10.1002/cbic.200500005
Klein, 2007, New chemical tools for investigating human mitotic kinesin Eg5, Bioorg. Med. Chem., 15, 6474, 10.1016/j.bmc.2007.06.016
Leizerman, 2004, Differential effects of monastrol in two human cell lines, Cell. Mol. Life Sci.: CMLS, 61, 2060, 10.1007/s00018-004-4074-3
Russowsky, 2006, Synthesis and differential antiproliferative activity of Biginelli compounds against cancer cell lines: Monastrol, oxo-monastrol and oxygenated analogues, Bioorg. Chem., 34, 173, 10.1016/j.bioorg.2006.04.003
Asraf, 2015, Mitotic slippage and expression of survivin are linked to differential sensitivity of human cancer cell-lines to the Kinesin-5 inhibitor monastrol, PLoS ONE, 10, 10.1371/journal.pone.0129255
Prasanna, 2009, Topological polar surface area: a useful descriptor in 2D-QSAR, Curr. Med. Chem., 16, 21, 10.2174/092986709787002817
Kumar, 2016, Discovery of potential ALK inhibitors by virtual screening approach. 3, Biotech, 6, 21
Adams, 2012, The Valley of Death in anticancer drug development: a re-assessment, Trends Pharmacol. Sci., 33, 173, 10.1016/j.tips.2012.02.001
Daina, 2016, A boiled-Egg to predict gastrointestinal absorption and brain penetration of small molecules, ChemMedChem., 11, 1117, 10.1002/cmdc.201600182