Endothelin influences pHi of human platelets through protein kinase C mediated pathways

Masaki, 1991, Molecular and cellular mechanisms of endothelin regulation, Circulation, 84, 1457, 10.1161/01.CIR.84.4.1457

Monnier de Gouville, 1989, Endothelin- a new family of endothelium-derived peptides with widespread biological properties, Life Sciences, 45, 1499, 10.1016/0024-3205(89)90415-3

Lovenberg, 1990, Endothelin: a review of its effects and possible mechanisms of action, Neurochem. Res., 15, 407, 10.1007/BF00969926

Ohlstein, 1990, Endothelin and platelet function, Throm. Res., 57, 967, 10.1016/0049-3848(90)90163-7

Thiemermann, 1990, Endothelin-1 inhibits platelet aggregation in vivo: a study with 111Indium-labeled platelets, Br. J. Pharmacol., 99, 303, 10.1111/j.1476-5381.1990.tb14699.x

Kato, 1992, Influence of endothelin on human platelet aggregation and prostacyclin generation from human vascular endothelial cells in culture, Jpn. Circ. J., 56, 422, 10.1253/jcj.56.422

Matsumoto, 1990, Potentiated effects of endothelin on platelet activation induced by epinephrine and ADP, Biochem. Pharm., 40, 909, 10.1016/0006-2952(90)90337-K

Astarie-Dequeker, 1992, In vitro inhibition by endothelins of thrombin-induced aggregation and Ca2+ mobilization in human platelets, Br. J. Pharmacol., 106, 966, 10.1111/j.1476-5381.1992.tb14443.x

Sakurai, 1992, Molecular characterization of endothelin receptors, Trends Pharmacol. Sci., 13, 103, 10.1016/0165-6147(92)90038-8

Panek, 1992, Endothelin and structurally related analogs distinguish between endothelin receptor subytpes, Biochem. Biophys. Res. Commun., 183, 566, 10.1016/0006-291X(92)90519-Q

Diochot, 1992, Effects of endothelins on the human megakaryoblastic cell line MEG-01, Eur. J. Pharm., 227, 427, 10.1016/0922-4106(92)90161-N

Simonson, 1990, Cellular signaling peptides of the endothelin gene family, FASEB J, 4, 2989, 10.1096/fasebj.4.12.2168326

OZAKI, Y., MATSUMOTO, Y., YATOMI, Y., HIGASHIHARA, M., KUME, S. Modification of Na+H+ exchanger in human platelets by 1,2-dioctanoylglycerol, a protein dinase C activator. Thromb. Haemost. 64 (1), 165–171.

Gende, 1991, The Na+H+ exchanger role in the intracellular pH regulation of human platelets, Arch. Int. Phys. Biochem. Biophys., 99, 95, 10.3109/13813459109145910

NACHMIAS, V.T., YOSHIDA, K.-I.,GLENNON, M.C. Lowering pH in blood platelets dissociates myosin phosphorylation from shape change and myosin association with the cytoskeleton. J. Cell Biol. 105, 1761–1769.

Luzzatto, 1991, Regulation of the phosphoinositide cycle by Na+H+ exchange and intracellular pH in human platelets, Bioch. Biophys. Acta, 1084, 78, 10.1016/0005-2760(91)90058-P

Siess, 1989, Molecular mechanisms of platelet activation, Physiol. Rev., 69, 58, 10.1152/physrev.1989.69.1.58

Marcus, 1993, Thromboregulation: multicellular modulation of platelet reactivity in hemostasis and thrombosis, FASEB J, 7, 516, 10.1096/fasebj.7.6.8472890

Sage, 1990, Agonist-evoked changes in cytosolic pH and calcium concentration in human platelets: studies in physiological bicarbonate, J. Physiol., 420, 31, 10.1113/jphysiol.1990.sp017900

Clemens, 1990, Thrombin-induced cytosolic alkalinization in human platelets occurs without an apparent involvement of HCO−3Cl−exchange, Pflugers Archiv, 416, 68, 10.1007/BF00370224

Zavoico, 1986, Regulation of intracellular pH in human platelets. Effects of thrombin, A23187 and inomycin and evidence for activation of Na+H+ exchange and its inhibition by amiloride analogues, J. Biol. Chem., 261, 3160, 10.1016/S0021-9258(18)69284-1

Touyz, 1993, Effects of angiotensin II and endothelin-1 on platelet aggregation and cytosolic pH and free Ca2+ concentrations in essential hypertension, Hypertension, 22, 853, 10.1161/01.HYP.22.6.853

Thiermermann, 1989, Endothelin-1 releases prostacyclin and inhibits ex vivo platelet aggregation in the anaesthetized rabbit, J. Cardiovasc. Pharmacol, 13, S138, 10.1097/00005344-198900135-00034

Pietraszek, 1992, Endothelins inhibit serotonin-induced platelet aggregation via a mechanism involving protein kinase C, Eur. J. Pharm., 25, 289, 10.1016/0014-2999(92)90308-Q

Astarie, 1989, Platelet cytosolic proton and free calcium concentrations in essential hypertension, J. Hypertens., 7, 485, 10.1097/00004872-198906000-00008

THOMAS, J.A., BUCHSBAUM, R.N., ZIMNIAK, A., RACKER E. Intracellular pH measurements in Ehrlich ascites tumor cells utilizing spectroscopic probes generated in situ. Biochemistry 18, 2210–2218.

Siffert, 1987, Activation of sodium-proton exchange is a prerequisite for Ca2+ mobilization in human platelets, Nature, 325, 456, 10.1038/325456a0

Ishikawa, 1989, Effect of cytoplasmic pH on platelet activation by arachidonic acid, Thromb. Res., 54, 17, 10.1016/0049-3848(89)90333-2

Kageyama, 1991, Is staurosporine a specific inhibitor of protein kinase C in intact porcine coronary arteries?, J. Pharmacol. Exp. Ther., 259, 1019

Watson, 1988, The action of protein kinase C inhibitor, staurosporine on human platelets. Evidence against a regulatory role for protein kinase C in the formation of inositol trisphosphate by thrombin, Biochem. J., 249, 345, 10.1042/bj2490345

Kobayashi, 1989, Calphostin C (UCN-1028 C), a novel microbial coumpound, is a highly potent and specific inhibitor of protein kinase C, Biochem. Biophys. Res. Commun., 159, 548, 10.1016/0006-291X(89)90028-4

Liu, 1992, Activation of multiple mechanisms including phospholipase D by endothelin-1 in rat aorta, Am. J. Physiol., 202, C941, 10.1152/ajpcell.1992.262.4.C941

LOFFEEHOLTZ, K. Receptor regulation of choline phospholipid hydrolysis. Biochem. Pharmacol. 38: 1543–1549.

Luscher, 1993, Molecular and cellular biology of endothelin and its receptors, J. Hypertens., 11, 7, 10.1097/00004872-199301000-00002

Vittet, 1992, Platelet receptor expression on three human megakaryoblast-like cell lines, Exp. Hemat., 20, 1129