Stimuli-responsive liposomal nanoformulations in cancer therapy: Pre-clinical & clinical approaches

Ashrafizadeh, 2022, 45 Ferreira-Faria, 2022 Xin, 2016, vol. 379, 24 Shi, 2016, 29, 282 Lopes, 2022, 6 Ashrafizadeh, 2022, 448 Wang, 2017, vol. 2, 1 Li, 2019, 1, 345 Li, 2020, 7, 455 Rasheed, 2018, The smart chemistry of stimuli-responsive polymeric carriers for target drug delivery applications, vol. 1, 61 Duncan, 2010, 62, 272 Wicki, 2015, 200, 138 Sinha, 2006, vol. 5, 1909 Alavi, 2017, 7, 3 Delfi, 2021, 38 Bor, 2019, vol. 10, 113 Mirzaei, 2021, 10, 3348 Xiao, 2019, 12, 1 El-Hammadi, 2019, vol. 29, 891 Lee, 2017, vol. 9, e1450 Fouladi, 2017, vol. 28, 857 Qiu, 2020, 11, 2811 Liu, 2018, 13, 38 Zheng, 2020, 11, 1476 Heidari, 2022, Biosynthesized Nanomaterials with Antioxidant and Antimicrobial Properties, Mater. Chem. Horizons, 1, 35 Liu, 2011, 6, 2143 Soukasene, 2011, 5, 9113 Wu, 2011, 7, 2040 Kim, 2009, 6, 978 Hu, 2014, 9, 319 Saravanakumar, 2019, 25, 2609 Zhao, 2021, 18, 319 Qiao, 2019, vol. 11, e1527 Yao, 2016, 11, 585 Liu, 2020, 17, 282 Sun, 2019, 17, 373 Zhao, 2012, 33, 2508 Zhao, 2016, 222, 56 Kuppusamy, 2002, 62, 307 Schafer, 2001, 30, 1191 Miao, 2020, 12, 1 Li, 2020, 3, 1283 Deng, 2018, 57, 8896 Du, 2019, 17, 262 Lu, 2016, 2, 1 Kamaly, 2016, 116, 2602 Harnoy, 2014, 136, 7531 Zelzer, 2013, vol. 1, 11 Chen, 2018, 10, 3929 Amiri-Kordestani, 2014, 20, 4436 Heneweer, 2012, vol. 3, 645 Alavi, 2019, 34 Rahimnejad, 2021 Patil, 2014, vol. 177, 8 Bhatia, 2021, Combinatorial liposomes of berberine and curcumin inhibit biofilm formation and intracellular methicillin resistant Staphylococcus aureus infections and associated inflammation, J. Mater. Chem. B, 9, 864, 10.1039/D0TB02036B Zhang, 2020, Curcumin- and cyclopamine-loaded liposomes to enhance therapeutic efficacy against hepatic fibrosis, Drug Des. Dev. Ther., 14, 5667, 10.2147/DDDT.S287442 Cheng, 2018, Cisplatin and curcumin co-loaded nano-liposomes for the treatment of hepatocellular carcinoma, Int. J. Pharm., 545, 261, 10.1016/j.ijpharm.2018.05.007 Al Saqr, 2020, Co-delivery of hispolon and doxorubicin liposomes improves efficacy against melanoma cells, AAPS PharmSciTech, 21, 304, 10.1208/s12249-020-01846-2 Wang, 2019, 303, 130 Moghaddam, 2022, Application of Microfluidic Platforms in Cancer Therapy, Mater. Chem. Horizons, 1, 69 Dutt, 2017, 7, 5733 Farjadian, 2018, 36, 968 Gregoriadis, 2000, 137 Felgner, 1987, 84, 7413 Kim, 2011, 21, 3734 Mintzer, 2009, vol. 109, 259 Niculescu-Duvaz, 2003, 10, 1233 Li, 2019, 164, 640 Tang, 1999, 62, 345 Tang, 1998, Introduction of a disulfide bond into a cationic lipid enhances transgene expression of plasmid, DNA, 242, 141 Yuba, 2020, 8, 1093 Woodle, 1995, 16, 249 Blume, 1990, vol. 1029, 91 Klibanov, 1990, 268, 235 Chaw, 2021, In vivo fate of liposomes after subconjunctival ocular delivery, J. Control. Release, 329, 162, 10.1016/j.jconrel.2020.11.053 Zhang, 2021, Brain-targeted delivery of obidoxime, using aptamer-modified liposomes, for detoxification of organophosphorus compounds, J. Control. Release, 329, 1117, 10.1016/j.jconrel.2020.10.039 Abbasi, 2021, Functionalized liposomes as drug nanocarriers for active targeted cancer therapy: a systematic review, J. Liposome Res., 1 Liu, 2020, Liposomes: preparation, characteristics, and application strategies in analytical chemistry, Crit. Rev. Anal. Chem., 1 Elkhoury, 2021, 13, 392 Kim, 2021, 57, 27 Nakhaei, 2021, 9 Panahi, 2017, 45, 788 Torchilin, 2005, vol. 4, 145 Mirzaei, 2021, 119430 Mirzaei, 2021, 119368 Ashrafizade, 2021, 117809 Ashrafizadeh, 2020, 12, 1084 Najafi, 2021, Gene regulation by antisense transcription: A focus on neurological and cancer diseases, Biomed. Pharm., 145 Aghamiri, 2021, Antimicrobial peptides as potential therapeutics for breast cancer, Pharmacol. Res., 171, 10.1016/j.phrs.2021.105777 Hattori, 2020, Effects of cationic lipids in cationic liposomes and disaccharides in the freeze-drying of siRNA lipoplexes on gene silencing in cells by reverse transfection, J. Liposome Res., 30, 235, 10.1080/08982104.2019.1630643 Jubair, 2021, CRISPR/Cas9-loaded stealth liposomes effectively cleared established HPV16-driven tumours in syngeneic mice, PLoS One, 16, 10.1371/journal.pone.0223288 Murugesan, 2020, Tuftsin-bearing liposomes co-encapsulated with doxorubicin and curcumin efficiently inhibit EAC tumor growth in mice, Int. J. Nanomedicine, 15, 10547, 10.2147/IJN.S276336 Wu, 2020, Curcumin-loaded liposomes prepared from bovine milk and krill phospholipids: effects of chemical composition on storage stability, in-vitro digestibility and anti-hyperglycemic properties, Food Res. Int. (Ottawa, Ont.), 136 Vangala, 2020, Combating glioblastoma by codelivering the small-molecule inhibitor of STAT3 and STAT3siRNA with α5β1 integrin receptor-selective liposomes, Mol. Pharm., 17, 1859, 10.1021/acs.molpharmaceut.9b01271 Mehta, 2021, Liposomes as versatile platform for cancer theranostics: therapy, bio-imaging and toxicological aspects, Curr. Pharm. Des., 17, 1977, 10.2174/1381612827666210311142100 Wu, 2020, Fluorescence imaging-guided multifunctional liposomes for tumor-specific phototherapy for laryngeal carcinoma, Biomater. Sci., 8, 3443, 10.1039/D0BM00249F Simões, 2004, 56, 947 Torchilin, 2009, 71, 431 Cullis, 1979, 559, 399 De Oliveira, 1998, 1372, 301 Rabiee, 2020, 232 Movagharnezhad, 2022, Synthesis of Poly (N-vinylpyrrolidone)-grafted-Magnetite Bromoacetylated Cellulose via ATRP for Drug Delivery, Mater. Chem. Horizons, 1, 89 Felber, 2012, pH-sensitive vesicles, polymeric micelles, and nanospheres prepared with polycarboxylates, Adv. Drug Deliv. Rev., 64, 979, 10.1016/j.addr.2011.09.006 Ghanbarzadeh, 2014, Improvement of the antiproliferative effect of rapamycin on tumor cell lines by poly (monomethylitaconate)-based pH-sensitive, plasma stable liposomes, Colloids Surf. B: Biointerfaces, 115, 323, 10.1016/j.colsurfb.2013.12.024 Han, 2016, Switchable liposomes: targeting-peptide-functionalized and pH-triggered cytoplasmic delivery, ACS Appl. Mater. Interfaces, 8, 18658, 10.1021/acsami.6b05678 Rabiee, 2021, Calcium-based nanomaterials and their interrelation with chitosan: optimization for pCRISPR delivery, J. Nanostructure Chem. Yuba, 2015, pH-sensitive polymer-liposome-based antigen delivery systems potentiated with interferon-γ gene lipoplex for efficient cancer immunotherapy, Biomaterials, 67, 214, 10.1016/j.biomaterials.2015.07.031 Zalipsky, 1995, 16, 157 Jain, 2010, 7, 653 Simoes, 2001, 1515, 23 Yang, 2017, pH-sensitive PEGylated liposomes for delivery of an acidic dinitrobenzamide mustard prodrug: pathways of internalization, cellular trafficking and cytotoxicity to cancer cells, Int. J. Pharm., 516, 323, 10.1016/j.ijpharm.2016.11.041 Kanamala, 2018, PEG-benzaldehyde-hydrazone-lipid based PEG-sheddable pH-sensitive liposomes: abilities for endosomal escape and long circulation, Pharm. Res., 35, 154, 10.1007/s11095-018-2429-y Xia, 2018, pH sensitive liposomes delivering tariquidar and doxorubicin to overcome multidrug resistance of resistant ovarian cancer cells, Colloids Surf. B: Biointerfaces, 170, 514, 10.1016/j.colsurfb.2018.06.055 Jain, 2018, 18, 44 Allen, 2013, vol. 65, 36 Mitragotri, 2017 Venditto, 2013, 65, 80 Lammers, 2016, 1, 1 Kanamala, 2016, 85, 152 Yatvin, 1980, 210, 1253 Ashrafizadeh, 2021, Hyaluronic acid-based nanoplatforms for doxorubicin: a review of stimuli-responsive carriers, co-delivery and resistance suppression, Carbohydr. Polym., 272, 10.1016/j.carbpol.2021.118491 Tang, 2019, Can intracellular drug delivery using hyaluronic acid functionalised pH-sensitive liposomes overcome gemcitabine resistance in pancreatic cancer?, J. Control. Release, 305, 89, 10.1016/j.jconrel.2019.05.018 Nik, 2020, 299 Lohade, 2016, 17, 1298 Soe, 2018, 170, 718 Nunes, 2021, pH-responsive and folate-coated liposomes encapsulating irinotecan as an alternative to improve efficacy of colorectal cancer treatment, Biomed. Pharmacother., 144, 10.1016/j.biopha.2021.112317 Monteiro, 2018, Paclitaxel-loaded folate-coated long circulating and pH-sensitive liposomes as a potential drug delivery system: a biodistribution study, Biomed. Pharm., 97, 489, 10.1016/j.biopha.2017.10.135 Abadi, 2021 Ikeda, 2008, 52, 26 Shanmugam, 2012, 320, 158 Wu, 2012, 35, 543 Wang, 2021, Ursolic acid inhibits breast cancer metastasis by suppressing glycolytic metabolism via activating SP1/Caveolin-1 signaling, Front. Oncol., 11 Rocha, 2016, Evaluation of antitumor activity of long-circulating and pH-sensitive liposomes containing ursolic acid in animal models of breast tumor and gliosarcoma, Integrative Cancer Ther., 15, 512, 10.1177/1534735416628273 Amini, 2021, 21, 142 Ashrafizaveh, 2021 Wang, 2017, Gold nanoshell coated thermo-pH dual responsive liposomes for resveratrol delivery and chemo-photothermal synergistic cancer therapy, J. Mater. Chem. B, 5, 2161, 10.1039/C7TB00258K Uda, 2020, pH-triggered solubility and cytotoxicity changes of malachite green derivatives incorporated in liposomes for killing cancer cells, J. Mater. Chem. B, 8, 8242, 10.1039/D0TB01346C Mirzaei, 2021, 10, 349 Rabiee, 2021 Rabiee, 2021, 13, 10796 de Oliveira Silva, 2019, Folate-coated, long-circulating and pH-sensitive liposomes enhance doxorubicin antitumor effect in a breast cancer animal model, Biomed. Pharmacother., 118, 10.1016/j.biopha.2019.109323 Vafajoo, 2018, 4 Maghsoudi, 2019, 53, 101146 Burande, 2020, EGFR targeted paclitaxel and piperine co-loaded liposomes for the treatment of triple negative breast cancer, AAPS PharmSciTech, 21, 151, 10.1208/s12249-020-01671-7 Boratto, 2020, Alpha-tocopheryl succinate improves encapsulation, pH-sensitivity, antitumor activity and reduces toxicity of doxorubicin-loaded liposomes, Eur. J. Pharm. Sci., 144, 10.1016/j.ejps.2019.105205 Ding, 2020, Designing aptamer-gold nanoparticle-loaded pH-sensitive liposomes encapsulate morin for treating cancer, Nanoscale Res. Lett., 15, 68, 10.1186/s11671-020-03297-x Monteiro, 2019, Paclitaxel-loaded folate-coated pH-sensitive liposomes enhance cellular uptake and antitumor activity, Mol. Pharm., 16, 3477, 10.1021/acs.molpharmaceut.9b00329 Mahira, 2019, Cabazitaxel and silibinin co-encapsulated cationic liposomes for CD44 targeted delivery: a new insight into nanomedicine based combinational chemotherapy for prostate cancer, Biomed. Pharmacother., 110, 803, 10.1016/j.biopha.2018.11.145 Park, 2021, pH-sensitive multi-drug liposomes targeting folate receptor β for efficient treatment of non-small cell lung cancer, J. Control. Release, 330, 1, 10.1016/j.jconrel.2020.12.011 Swami, 2021, pH sensitive liposomes assisted specific and improved breast cancer therapy using co-delivery of SIRT1 shRNA and docetaxel, Mater. Sci. Eng. C Mater. Biol. Appl., 120, 10.1016/j.msec.2020.111664 Xu, 2021, Co-delivery using pH-sensitive liposomes to pancreatic cancer cells: the effects of curcumin on cellular concentration and pharmacokinetics of gemcitabine, Pharm. Res., 38, 1209, 10.1007/s11095-021-03072-2 Ba, 2021, Construction of hierarchical-targeting pH-sensitive liposomes to reverse chemotherapeutic resistance of cancer stem-like cells, Pharmaceutics, 13, 10.3390/pharmaceutics13081205 Salmaso, 2021, Tyrosine kinase inhibitor prodrug-loaded liposomes for controlled release at tumor microenvironment, J. Control. Release, 340, 318, 10.1016/j.jconrel.2021.11.006 Saraf, 2021, Engineered liposomes bearing camptothecin analogue for tumour targeting: in vitro and ex-vivo studies, J. Liposome Res., 31, 326, 10.1080/08982104.2020.1801725 Feng, 2021, Antitumor effect of hyperoside loaded in charge reversed and mitochondria-targeted liposomes, Int. J. Nanomedicine, 16, 3073, 10.2147/IJN.S297716 Lopes, 2021, Modelling the impact of nucleolin expression level on the activity of F3 peptide-targeted pH-sensitive pegylated liposomes containing doxorubicin, Drug Deliv. Transl. Res., 12, 629, 10.1007/s13346-021-00972-z Gautam, 2020, Phytosterol-loaded CD44 receptor-targeted PEGylated nano-hybrid phyto-liposomes for synergistic chemotherapy, Expert Opin. Drug Deliv., 17, 423, 10.1080/17425247.2020.1727442 Zhang, 2018, Eph A10-modified pH-sensitive liposomes loaded with novel triphenylphosphine-docetaxel conjugate possess hierarchical targetability and sufficient antitumor effect both in vitro and in vivo, Drug Deliv., 25, 723, 10.1080/10717544.2018.1446475 Ding, 2017, In vivo study of doxorubicin-loaded cell-penetrating peptide-modified pH-sensitive liposomes: biocompatibility, bio-distribution, and pharmacodynamics in BALB/c nude mice bearing human breast tumors, Drug Des. Dev. Ther., 11, 3105, 10.2147/DDDT.S149814 Okazaki, 2018, Evaluation of pH-sensitive fusogenic polymer-modified liposomes co-loaded with antigen and α-galactosylceramide as an anti-tumor vaccine, J. Vet. Med. Sci., 80, 197, 10.1292/jvms.17-0491 Yuba, 2018, Bleomycin-loaded pH-sensitive polymer−lipid-incorporated liposomes for cancer chemotherapy, Polymers, 10, 10.3390/polym10010074 Tian, 2016, 6, 49250 Raza, 2018, Redox-responsive nano-carriers as tumor-targeted drug delivery systems, Eur. J. Med. Chem., 157, 705, 10.1016/j.ejmech.2018.08.034 Feng, 2019, Engineering of bone- and CD44-dual-targeting redox-sensitive liposomes for the treatment of orthotopic osteosarcoma, ACS Appl. Mater. Interfaces, 11, 7357, 10.1021/acsami.8b18820 Chi, 2017, Redox-sensitive and hyaluronic acid functionalized liposomes for cytoplasmic drug delivery to osteosarcoma in animal models, J. Control. Release, 261, 113, 10.1016/j.jconrel.2017.06.027 Chen, 2020, Stimuli-responsive polysaccharide enveloped liposome for targeting and penetrating delivery of survivin-shRNA into breast tumor, ACS Appl. Mater. Interfaces, 12, 22074, 10.1021/acsami.9b22440 Chen, 2017, Co-delivery of paclitaxel and anti-survivin siRNA via redox-sensitive oligopeptide liposomes for the synergistic treatment of breast cancer and metastasis, Int. J. Pharm., 529, 102, 10.1016/j.ijpharm.2017.06.071 Fu, 2015, Tumor-targeted paclitaxel delivery and enhanced penetration using TAT-decorated liposomes comprising redox-responsive poly(ethylene glycol), J. Pharm. Sci., 104, 1160, 10.1002/jps.24291 Yu, 2019, Redox-responsive tetraphenylethylene-buried crosslinked vesicles for enhanced drug loading and efficient drug delivery monitoring, J. Mater. Chem. B, 7, 7540, 10.1039/C9TB01639B He, 2021, Redox responsive 7-ethyl-10-hydroxycamptothecin (SN38) lysophospholipid conjugate: synthesis, assembly and anticancer evaluation, Int. J. Pharm., 606, 10.1016/j.ijpharm.2021.120856 Zhou, 2016, Redox responsive liposomal nanohybrid cerasomes for intracellular drug delivery, Colloids Surf. B: Biointerfaces, 148, 518, 10.1016/j.colsurfb.2016.09.033 Wang, 2020, A novel CD133- and EpCAM-targeted liposome with redox-responsive properties capable of synergistically eliminating liver cancer stem cells, Front. Chem., 8, 649, 10.3389/fchem.2020.00649 Liu, 2019, Redox-activated porphyrin-based liposome remote-loaded with indoleamine 2,3-dioxygenase (IDO) inhibitor for synergistic photoimmunotherapy through induction of immunogenic cell death and blockage of IDO pathway, Nano Lett., 19, 6964, 10.1021/acs.nanolett.9b02306 Lou, 2020, Reactive oxygen species-responsive liposomes via boronate-caged phosphatidylethanolamine, Bioconjug. Chem., 31, 2220, 10.1021/acs.bioconjchem.0c00397 Pedersen, 2010, Liposomal formulation of retinoids designed for enzyme triggered release, J. Med. Chem., 53, 3782, 10.1021/jm100190c Chen, 2018, Dimeric BODIPY-loaded liposomes for dual hypoxia marker imaging and activatable photodynamic therapy against tumors, J. Mater. Chem. B, 6, 4351, 10.1039/C8TB00665B Wan, 2013, Enzyme-responsive liposomes modified adenoviral vectors for enhanced tumor cell transduction and reduced immunogenicity, Biomaterials, 34, 3020, 10.1016/j.biomaterials.2012.12.051 Haemmerich, 2018, vol. 139, 121 Kong, 2000, 60, 6950 Yatvin, 1978, 202, 1290 Mumtaz, 1991, 1, 505 Papahadjopoulos, 1991, 88, 11460 Magin, 1986, 3, 223 Sadeghi, 2018, 548, 778 Gaber, 1995, 12, 1407 Burke, 2018, 34, 786 Needham, 2000, 60, 1197 Kirtonia, 2021 Ashrafizadeh, 2021, 141 Soleymani, 2021 Jin, 2020, Indocyanine green-parthenolide thermosensitive liposome combination treatment for triple-negative breast cancer, Int. J. Nanomedicine, 15, 3193, 10.2147/IJN.S245289 Ye, 2021, A novel targeted therapy system for cervical cancer: co-delivery system of antisense LncRNA of MDC1 and oxaliplatin magnetic thermosensitive cationic liposome drug carrier, Int. J. Nanomedicine, 16, 1051, 10.2147/IJN.S258316 Petrini, 2021, Effects of surface charge, PEGylation and functionalization with dipalmitoylphosphatidyldiglycerol on liposome-cell interactions and local drug delivery to solid tumors via thermosensitive liposomes, Int. J. Nanomedicine, 16, 4045, 10.2147/IJN.S305106 Alawak, 2021, ADAM 8 as a novel target for doxorubicin delivery to TNBC cells using magnetic thermosensitive liposomes, Eur. J. Pharm. Biopharm., 158, 390, 10.1016/j.ejpb.2020.12.012 van Valenberg, 2021, Int. J. Nanomedicine, 16, 75, 10.2147/IJN.S280034 Brummelhuis, 2021, DPPG(2)-based thermosensitive liposomes as drug delivery system for effective muscle-invasive bladder cancer treatment in vivo, Int. J. Hyperth., 38, 1415, 10.1080/02656736.2021.1983038 Yang, 2020, Thermosensitive liposomes encapsulating anti-cancer agent lomustine, and contrast medium iohexol, for thermochemotherapy: preparation, characterization, and in vivo evaluation, J. Nanosci. Nanotechnol., 20, 6070, 10.1166/jnn.2020.18590 Mikhail, 2017, Lyso-thermosensitive liposomal doxorubicin for treatment of bladder cancer, Int. J. Hyperth., 33, 733 Farcas, 2020, Thermosensitive betulinic acid-loaded magnetoliposomes: a promising antitumor potential for highly aggressive human breast adenocarcinoma cells under hyperthermic conditions, Int. J. Nanomedicine, 15, 8175, 10.2147/IJN.S269630 Li, 2018, The comparative effect of wrapping solid gold nanoparticles and hollow gold nanoparticles with doxorubicin-loaded thermosensitive liposomes for cancer thermo-chemotherapy, Nanoscale, 10, 8628, 10.1039/C7NR09083H Du, 2020, F7 and topotecan co-loaded thermosensitive liposome as a nano-drug delivery system for tumor hyperthermia, Drug Deliv., 27, 836, 10.1080/10717544.2020.1772409 Santos, 2017, Focused ultrasound hyperthermia mediated drug delivery using thermosensitive liposomes and visualized with in vivo two-photon microscopy, Theranostics, 7, 2718, 10.7150/thno.19662 Fu, 2019, K237-modified thermosensitive liposome enhanced the delivery efficiency and cytotoxicity of paclitaxel in vitro, J. Liposome Res., 29, 86, 10.1080/08982104.2018.1458863 Rysin, 2021, Evaluation of release and pharmacokinetics of hexadecylphosphocholine (miltefosine) in phosphatidyldiglycerol-based thermosensitive liposomes, Biochim. Biophys. Acta Biomembr., 1863, 10.1016/j.bbamem.2021.183698 Dai, 2019, Multifunctional thermosensitive liposomes based on natural phase-change material: near-infrared light-triggered drug release and multimodal imaging-guided cancer combination therapy, ACS Appl. Mater. Interfaces, 11, 10540, 10.1021/acsami.8b22748 Centelles, 2018, Image-guided thermosensitive liposomes for focused ultrasound drug delivery: using NIRF-labelled lipids and topotecan to visualise the effects of hyperthermia in tumours, J. Control. Release, 280, 87, 10.1016/j.jconrel.2018.04.047 Lv, 2020, Thermosensitive exosome-liposome hybrid nanoparticle-mediated chemoimmunotherapy for improved treatment of metastatic peritoneal cancer, Adv. Sci. (Weinheim, Baden-Wurttemberg, Germany), 7 Cressey, 2021, Image-guided thermosensitive liposomes for focused ultrasound enhanced co-delivery of carboplatin and SN-38 against triple negative breast cancer in mice, Biomaterials, 271, 10.1016/j.biomaterials.2021.120758 Zhang, 2021, Development of thermosensitive resiquimod-loaded liposomes for enhanced cancer immunotherapy, J. Control. Release, 330, 1080, 10.1016/j.jconrel.2020.11.013 Xi, 2020, Novel thermosensitive polymer-modified liposomes as nano-carrier of hydrophobic antitumor drugs, J. Pharm. Sci., 109, 2544, 10.1016/j.xphs.2020.05.006 Eleftheriou, 2020, A combination drug delivery system employing thermosensitive liposomes for enhanced cell penetration and improved in vitro efficacy, Int. J. Pharm., 574, 10.1016/j.ijpharm.2019.118912 Dorjsuren, 2020, Cetuximab-coated thermo-sensitive liposomes loaded with magnetic nanoparticles and doxorubicin for targeted EGFR-expressing breast cancer combined therapy, Int. J. Nanomedicine, 15, 8201, 10.2147/IJN.S261671 Wei, 2017, Thermosensitive liposomal codelivery of HSA-paclitaxel and HSA-ellagic acid complexes for enhanced drug perfusion and efficacy against pancreatic cancer, ACS Appl. Mater. Interfaces, 9, 25138, 10.1021/acsami.7b07132 Alawak, 2020, Magnetic resonance activatable thermosensitive liposomes for controlled doxorubicin delivery, Mater. Sci. Eng. C Mater. Biol. Appl., 115, 10.1016/j.msec.2020.111116 Alvarez-Lorenzo, 2009, 85, 848 Shum, 2001, 53, 273 Mittal, 2002 Kono, 2006 Shah, 2016, Doxorubicin-loaded photosensitive magnetic liposomes for multi-modal cancer therapy, Colloids Surf. B: Biointerfaces, 148, 157, 10.1016/j.colsurfb.2016.08.055 Huang, 2008, vol. 60, 1167 Gerasimov, 1999, 38, 317 O'Brien, 1998, 31, 861 Bondurant, 1998, 120, 13541 Clapp, 1997, 30, 32 Thompson, 1996, Triggerable plasmalogen liposomes: improvement of system efficiency, Biochim. Biophys. Acta, 1279, 25, 10.1016/0005-2736(95)00210-3 Anderson, 1992, 1109, 33 Kano, 1981, 34, 323 Bigham, 2020, The journey of multifunctional bone scaffolds fabricated from traditional toward modern techniques, Bio-Des. Manuf., 3, 281, 10.1007/s42242-020-00094-4 Cao, 2017, Efficient cancer regression by a thermosensitive liposome for photoacoustic imaging-guided photothermal/chemo combinatorial therapy, Biomacromolecules, 18, 2306, 10.1021/acs.biomac.7b00464 Yang, 2018, Near-infrared light-activated IR780-loaded liposomes for anti-tumor angiogenesis and Photothermal therapy, Nanomedicine, 14, 2283, 10.1016/j.nano.2018.06.011 Yang, 2019, Near-infrared light triggered liposomes combining photodynamic and chemotherapy for synergistic breast tumor therapy, Colloids Surf. B: Biointerfaces, 173, 564, 10.1016/j.colsurfb.2018.10.019 Yang, 2021, Light-activatable liposomes for repetitive on-demand drug release and immunopotentiation in hypoxic tumor therapy, Biomaterials, 265, 10.1016/j.biomaterials.2020.120456 Das, 2020, Effect of laser irradiation on reversibility and drug release of light-activatable drug-encapsulated liposomes, Langmuir, 36, 3573, 10.1021/acs.langmuir.0c00215 Li, 2020, Using magnetic and photic stimuli-responsive liposomes to serve up chemotherapy drugs to cancer cells, J. Biomed. Nanotechnol., 16, 867, 10.1166/jbn.2020.2946 Zhang, 2018, Light-triggered theranostic liposomes for tumor diagnosis and combined photodynamic and hypoxia-activated prodrug therapy, Biomaterials, 185, 301, 10.1016/j.biomaterials.2018.09.033 Fuse, 2018, Effective light-triggered contents release from helper lipid-incorporated liposomes co-encapsulating gemcitabine and a water-soluble photosensitizer, Int. J. Pharm., 540, 50, 10.1016/j.ijpharm.2018.01.040 Yue, 2017, Mitochondria-targeting near-infrared light-triggered thermosensitive liposomes for localized photothermal and photodynamic ablation of tumors combined with chemotherapy, Nanoscale, 9, 11103, 10.1039/C7NR02193C Li, 2015, Human epidermal growth factor receptor-2 antibodies enhance the specificity and anticancer activity of light-sensitive doxorubicin-labeled liposomes, Biomaterials, 57, 1, 10.1016/j.biomaterials.2015.04.009 Kono, 2020, Surface modification of liposomes using IR700 enables efficient controlled contents release triggered by near-IR light, Biol. Pharm. Bull., 43, 736, 10.1248/bpb.b19-00864 Yu, 2021, Synergetic delivery of triptolide and Ce6 with light-activatable liposomes for efficient hepatocellular carcinoma therapy, Acta Pharm. Sin. B, 11, 2004, 10.1016/j.apsb.2021.02.001 Refaat, 2021, Near-infrared light-responsive liposomes for protein delivery: towards bleeding-free photothermally-assisted thrombolysis, J. Control. Release, 337, 212, 10.1016/j.jconrel.2021.07.024 Mohseni, 2020, 191 Bigham, 2020, 3, 281 Formica, 2004, 3, 1 Tang, 2021, 47 Bigham, 2021, 134146 Dwivedi, 2020, Magnetic targeting and ultrasound activation of liposome-microbubble conjugate for enhanced delivery of anticancer therapies, ACS Appl. Mater. Interfaces, 12, 23737, 10.1021/acsami.0c05308 Nguyen, 2017, Nanohybrid magnetic liposome functionalized with hyaluronic acid for enhanced cellular uptake and near-infrared-triggered drug release, Colloids Surf. B: Biointerfaces, 154, 104, 10.1016/j.colsurfb.2017.03.008 Sharifabad, 2016, Drug-loaded liposome-capped mesoporous core-shell magnetic nanoparticles for cellular toxicity study, Nanomedicine (London, England), 11, 2757 Szuplewska, 2019, Magnetic field-assisted selective delivery of doxorubicin to cancer cells using magnetoliposomes as drug nanocarriers, Nanotechnology, 30, 10.1088/1361-6528/ab19d3 Redolfi Riva, 2020, Enhanced in vitro magnetic cell targeting of doxorubicin-loaded magnetic liposomes for localized cancer therapy, Nanomaterials (Basel, Switzerland), 10 Thébault, 2020, Theranostic MRI liposomes for magnetic targeting and ultrasound triggered release of the antivascular CA4P, J. Control. Release, 322, 137, 10.1016/j.jconrel.2020.03.003 Wang, 2018, Novel redox-responsive polymeric magnetosomes with tunable magnetic resonance property for in vivo drug release visualization and dual-modal cancer therapy, Adv. Funct. Mater., 28 Ashrafizadeh, 2020, 11, 1785 Ashrafizadeh, 2020, 235, 9241 Ashrafizadeh, 2020 Ashrafizadeh, 2020, 256 Ashrafizadeh, 2020, 34, 1745 Ashrafizadeh, 2020, 20, 667 Hardiansyah, 2017, Hydrophobic drug-loaded PEGylated magnetic liposomes for drug-controlled release, Nanoscale Res. Lett., 12, 355, 10.1186/s11671-017-2119-4 Mohammadinejad, 2019, 234, 14914 Ashrafizadeh, 2021, 21, 1 Hussain, 2021, 13, 1602 Najafi, 2020, 1 Lin, 2020, Application of paclitaxel-loaded EGFR peptide-conjugated magnetic polymeric liposomes for liver cancer therapy, Curr. Med. Sci., 40, 145, 10.1007/s11596-020-2158-4 Liu, 2019, Magnet-activatable nanoliposomes as intracellular bubble microreactors to enhance drug delivery efficacy and burst cancer cells, Nanoscale, 11, 18854, 10.1039/C9NR07021D Tavakoli, 2021, Milk protein-based nanodelivery systems for the cancer treatment, J Nanostructure Chem, 11, 483, 10.1007/s40097-021-00399-5 Nasri, 2020, Thymoquinone-loaded ethosome with breast cancer potential: optimization, in vitro and biological assessment, J. Nanostructure Chem., 10, 19, 10.1007/s40097-019-00325-w Liang, 2008, Characterization of novel multifunctional cationic polymeric liposomes formed from octadecyl quaternized carboxymethyl chitosan/cholesterol and drug encapsulation, Langmuir, 24, 7147, 10.1021/la703775a Zhang, 2021, Novel timosaponin AIII-based multifunctional liposomal delivery system for synergistic therapy against hepatocellular carcinoma cancer, Int. J. Nanomedicine, 16, 5531, 10.2147/IJN.S313759 Rabiee, 2021, 11, 1 Hong, 2019, Novel ginsenoside-based multifunctional liposomal delivery system for combination therapy of gastric cancer, Theranostics, 9, 4437, 10.7150/thno.34953 Koren, 2012, Multifunctional PEGylated 2C5-immunoliposomes containing pH-sensitive bonds and TAT peptide for enhanced tumor cell internalization and cytotoxicity, J. Control. Release, 160, 264, 10.1016/j.jconrel.2011.12.002 Chen, 2021, In situ self-assembly of gold nanorods with thermal-responsive microgel for multi-synergistic remote drug delivery, Adv. Compos. Hybrid. Mater. Hua, 2017, Multifunctional gold nanorods and docetaxel-encapsulated liposomes for combined thermo- and chemotherapy, Int. J. Nanomedicine, 12, 7869, 10.2147/IJN.S143977 lian, 2021, Recent advances on the magnetic nanoparticle–based nanocomposites for magnetic induction hyperthermia of tumor: a short review, Adv. Compos. Hybrid Mater., 4, 925, 10.1007/s42114-021-00373-3 Tran, 2017, Engineering of multifunctional temperature-sensitive liposomes for synergistic photothermal, photodynamic, and chemotherapeutic effects, Int. J. Pharm., 528, 692, 10.1016/j.ijpharm.2017.06.069 Li, 2014, Multifunctional liposomes loaded with paclitaxel and artemether for treatment of invasive brain glioma, Biomaterials, 35, 5591, 10.1016/j.biomaterials.2014.03.049 Yuba, 2021, Multifunctional traceable liposomes with temperature-triggered drug release and neovasculature-targeting properties for improved cancer chemotherapy, Mol. Pharm., 18, 3342, 10.1021/acs.molpharmaceut.1c00263 He, 2014, Design of multifunctional magnetic iron oxide nanoparticles/mitoxantrone-loaded liposomes for both magnetic resonance imaging and targeted cancer therapy, Int. J. Nanomedicine, 9, 4055, 10.2147/IJN.S61880 Apte, 2014, Doxorubicin in TAT peptide-modified multifunctional immunoliposomes demonstrates increased activity against both drug-sensitive and drug-resistant ovarian cancer models, Cancer Biol. Ther., 15, 69, 10.4161/cbt.26609 Miranda, 2017, Multifunctional liposomes for image-guided intratumoral chemo-phototherapy, Adv. Healthcare Mater., 6, 10.1002/adhm.201700253