Evaluation of multiple-session delay eyeblink conditioning comparing patients with focal cerebellar lesions and cerebellar degeneration

Aksenov, 2004, GABA neurotransmission in the cerebellar interposed nuclei: involvement in classically conditioned eyeblinks and neuronal activity, J Neurophysiol, 91, 719, 10.1152/jn.00859.2003 Attwell, 2001, Acquisition of eyeblink conditioning is critically dependent on normal function in cerebellar cortical lobule HVI, J Neurosci, 21, 5715, 10.1523/JNEUROSCI.21-15-05715.2001 Attwell, 2002, Cerebellar mechanisms in eyeblink conditioning, Ann N Y Acad Sci, 978, 79, 10.1111/j.1749-6632.2002.tb07557.x Attwell, 2002, Cerebellar function in consolidation of a motor memory, Neuron, 34, 1011, 10.1016/S0896-6273(02)00719-5 Bracha, 1997, Patients with cerebellar lesions cannot acquire but are able to retain conditioned eyeblink reflexes, Brain, 120, 1401, 10.1093/brain/120.8.1401 Bracha, 2000, The human cerebellum and associative learning: dissociation between the acquisition, retention and extinction of conditioned eyeblinks, Brain Res, 860, 87, 10.1016/S0006-8993(00)01995-8 Brandauer, 2008, Impairments of prehension kinematics and grasping forces in patients with cerebellar degeneration and the relationship to cerebellar atrophy, Clin Neurophysiol, 119, 2528, 10.1016/j.clinph.2008.07.280 Brett, 2001, Spatial normalization of brain images with focal lesions using cost function masking, Neuroimage, 14, 486, 10.1006/nimg.2001.0845 Cheng, 2008, Neural substrates underlying human delay and trace eyeblink conditioning, Proc Natl Acad Sci USA, 105, 8108, 10.1073/pnas.0800374105 Christian, 2003, Neural substrates of eyeblink conditioning: acquisition and retention, Learn Mem, 11, 427, 10.1101/lm.59603 Cooke, 2004, Temporal properties of cerebellar-dependent memory consolidation, J Neurosci, 24, 2934, 10.1523/JNEUROSCI.5505-03.2004 Daum, 1993, Classical conditioning after cerebellar lesions in humans, Behav Neurosci, 107, 748, 10.1037/0735-7044.107.5.748 De Zeeuw, 2005, Time and tide in cerebellar memory formation, Curr Opin Neurobiol, 15, 667, 10.1016/j.conb.2005.10.008 Diedrichsen, 2009, A probabilistic MR atlas of the human cerebellum, Neuroimage, 46, 39, 10.1016/j.neuroimage.2009.01.045 Dimitrova, 2002, MRI atlas of the human cerebellar nuclei, Neuroimage, 17, 240, 10.1006/nimg.2002.1124 Dimitrova, 2006, Probabilistic 3D MRI atlas of the human cerebellar dentate/interposed nuclei, Neuroimage, 30, 12, 10.1016/j.neuroimage.2005.09.020 Gerwig, 2003, Comparison of eyeblink conditioning in patients with superior and posterior inferior cerebellar lesions, Brain, 126, 71, 10.1093/brain/awg011 Gerwig, 2004, Amplitude changes of unconditioned eyeblink responses in patients with cerebellar lesions, Exp Brain Res, 155, 341, 10.1007/s00221-003-1731-y Gerwig, 2005, Timing of conditioned eyeblink responses is impaired in cerebellar patients, J Neurosci, 25, 3919, 10.1523/JNEUROSCI.0266-05.2005 Gerwig, 2006, Extinction of conditioned eyeblink responses in patients with cerebellar disorders, Neurosci Lett, 406, 87, 10.1016/j.neulet.2006.07.017 Gerwig, 2007, The involvement of the human cerebellum in eyeblink conditioning, The Cerebellum, 6, 38, 10.1080/14734220701225904 Gruart, 1995, Cerebellar cortex and eyeblink conditioning: bilateral regulation of conditioned responses, Exp Brain Res, 104, 431, 10.1007/BF00231978 Harvey, 1993, Recoverable and nonrecoverable deficits in conditioned responses after cerebellar cortical lesions, J Neurosci, 13, 1624, 10.1523/JNEUROSCI.13-04-01624.1993 Kehoe, 1986, Compound-component differentiation as a function of CS-US interval and CS duration in the rabbit's nictitating membrane response, Ann Learn Behav, 14, 144, 10.3758/BF03200049 Kehoe, 2001, Fundamental behavioural methods and findings in classical conditioning, 171 Klockgether, 2007, Ataxias, 765 Koekkoek, 2003, Cerebellar LTD and learning dependent timing of conditioned eyelid responses, Science, 301, 1736, 10.1126/science.1088383 Lavond, 1989, Acquisition of classical conditioning without cerebellar cortex, Behav Brain Res, 33, 113, 10.1016/S0166-4328(89)80047-6 Linden, 2003, From molecules to memory in the cerebellum, Science, 301, 1682, 10.1126/science.1090462 Luft, 1998, A new semiautomated, three-dimensional technique allowing precise quantification of total and regional cerebellar volume using MRI, Magn Reson Med, 40, 143, 10.1002/mrm.1910400119 Lye, 1988, Effects of a unilateral cerebellar lesion on the acquisition of eye-blink conditioning in man, J Physiol, 403, 458 Makris, 2005, MRI-based surface-assisted parcellation of human cerebellar cortex: an anatomically specified method with estimate of reliability, Neuroimage, 25, 1146, 10.1016/j.neuroimage.2004.12.056 2002 McCormick, 1984, Cerebellum: essential involvement in the classically conditioned eyelid response, Science, 223, 296, 10.1126/science.6701513 McGlinchey-Berroth, 2002, Temporal discrimination learning in abstinent chronic alcoholics, Alcohol Clin Exp Res, 26, 804, 10.1111/j.1530-0277.2002.tb02608.x Perrett, 1993, Cerebellar cortex lesions disrupt learning-dependent timing of conditioned eyelid responses, J Neurosci, 13, 1708, 10.1523/JNEUROSCI.13-04-01708.1993 Ramnani, 2000, Learning- and expectation-related changes in the human brain during motor learning, J Neurophysiol, 84, 3026, 10.1152/jn.2000.84.6.3026 Richter, 2005, Degree of cerebellar ataxia correlates with three-dimensional MRI-based cerebellar volume in pure cerebellar degeneration, Eur Neurol, 54, 23, 10.1159/000087241 Robleto, 2004, Brain mechanisms of extinction of the classically conditioned eyeblink response, Learn Mem, 11, 517, 10.1101/lm.80004 Schmitz-Hübsch, 2006, Scale for the assessment and rating of ataxia: development of a new clinical scale, Neurology, 66, 1717, 10.1212/01.wnl.0000219042.60538.92 Steinmetz, 2000, Brain substrates of classical eyeblink conditioning: a highly localized but also distributed system, Behav Brain Res, 110, 13, 10.1016/S0166-4328(99)00181-3 Thompson, 1997, Associative learning, Int Rev Neurobiol, 41, 151, 10.1016/S0074-7742(08)60351-7 Thompson, 2005, In search of memory traces, Annu Rev Psychol, 56, 1, 10.1146/annurev.psych.56.091103.070239 Thompson, 2009, The role of the cerebellum in classical conditioning of discrete behavioral responses, Neuroscience, 162, 732, 10.1016/j.neuroscience.2009.01.041 Timmann, 2000, Alcoholic cerebellar degeneration, 571 Timmann, 2005, Eyeblink conditioning in patients with hereditary ataxia: a one year follow-up study, Exp Brain Res, 162, 332, 10.1007/s00221-004-2181-x Timmann, 2009, Current advances in lesion-symptom mapping of the human cerebellum, Neuroscience, 162, 836, 10.1016/j.neuroscience.2009.01.040 Topka, 1993, Deficit in classical conditioning in patients with cerebellar degeneration, Brain, 116, 961, 10.1093/brain/116.4.961 Woodruff-Pak, 1996, Cerebellar involvement in eyeblink classical conditioning in humans, Neuropsychology, 10, 443, 10.1037/0894-4105.10.4.443 2000 2000 Yeo, 1984, Discrete lesion of the cerebellar cortex abolish the classically conditioned nictitating membrane response of the rabbit, Behav Brain Res, 13, 261, 10.1016/0166-4328(84)90168-2 Yeo, 1985, Classical conditioning of the nictitating membrane response of the rabbit. II. Lesions of the cerebellar cortex, Exp Brain Res, 60, 99, 10.1007/BF00237023 Yeo, 1998, Cerebellum and conditioned reflexes, Trends Cogn Sci, 2, 322, 10.1016/S1364-6613(98)01219-4