miR-34a/SIRT1/p53 is suppressed by ursodeoxycholic acid in the rat liver and activated by disease severity in human non-alcoholic fatty liver disease

Journal of Hepatology - Tập 58 - Trang 119-125 - 2013
Rui E. Castro1,2, Duarte M.S. Ferreira1, Marta B. Afonso1, Pedro M. Borralho1,2, Mariana V. Machado3,4, Helena Cortez-Pinto3,4, Cecília M.P. Rodrigues1,2
1Research Institute for Medicines and Pharmaceutical Sciences (iMed.UL), Faculty of Pharmacy, University of Lisbon, Lisbon, Portugal
2Department of Biochemistry and Human Biology, Faculty of Pharmacy, University of Lisbon, Lisbon, Portugal
3Department of Gastroenterology, Hospital de Santa Maria, Lisbon, Portugal
4Instituto de Medicina Molecular, Faculty of Medicine, University of Lisbon, Lisbon, Portugal

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