Distinct Populations of Cancer Stem Cells Determine Tumor Growth and Metastatic Activity in Human Pancreatic Cancer

Cell Stem Cell - Tập 1 - Trang 313-323 - 2007
Patrick C. Hermann1, Stephan L. Huber1, Tanja Herrler1, Alexandra Aicher2, Joachim W. Ellwart3, Markus Guba1, Christiane J. Bruns1, Christopher Heeschen1
1Department of Surgery, Ludwig-Maximilians-University, 81377 Munich, Germany
2Department of Internal Medicine III, J.W. Goethe University, 60590 Frankfurt, Germany
3Institute of Molecular Immunology, Helmholtz Center for Environment and Health, 81377 Munich, Germany

Tài liệu tham khảo

Ahlgren, 1996, Chemotherapy for pancreatic carcinoma, Cancer, 78, 654, 10.1002/(SICI)1097-0142(19960801)78:3<654::AID-CNCR46>3.0.CO;2-V Al-Hajj, 2003, Prospective identification of tumorigenic breast cancer cells, Proc. Natl. Acad. Sci. USA, 100, 3983, 10.1073/pnas.0530291100 Bachelder, 2002, Vascular endothelial growth factor promotes breast carcinoma invasion in an autocrine manner by regulating the chemokine receptor CXCR4, Cancer Res., 62, 7203 Barnett, 1998, Oligodendrocyte-type-2 astrocyte (O-2A) progenitor cells transformed with c-myc and H-ras form high-grade glioma after stereotactic injection into the rat brain, Carcinogenesis, 19, 1529, 10.1093/carcin/19.9.1529 Bruns, 1999, In vivo selection and characterization of metastatic variants from human pancreatic adenocarcinoma by using orthotopic implantation in nude mice, Neoplasia, 1, 50, 10.1038/sj.neo.7900005 Burger, 2006, CXCR4: a key receptor in the crosstalk between tumor cells and their microenvironment, Blood, 107, 1761, 10.1182/blood-2005-08-3182 Clarke, 2006, Cancer stem cells–perspectives on current status and future directions: AACR workshop on cancer stem cells, Cancer Res., 66, 9339, 10.1158/0008-5472.CAN-06-3126 Dalerba, 2007, Cancer stem cells: models and concepts, Annu. Rev. Med., 58, 267, 10.1146/annurev.med.58.062105.204854 Denham, 2006, Neural stem cells express non-neural markers during embryoid body coculture, Stem Cells, 24, 918, 10.1634/stemcells.2005-0151 Dick, 2005, Acute myeloid leukemia stem cells, Ann. N Y Acad. Sci., 1044, 1, 10.1196/annals.1349.001 Dontu, 2003, In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells, Genes Dev., 17, 1253, 10.1101/gad.1061803 Fargeas, 2003, AC133 antigen, CD133, prominin-1, prominin-2, etc.: prominin family gene products in need of a rational nomenclature, Stem Cells, 21, 506, 10.1634/stemcells.21-4-506 He, 2007, PTEN-deficient intestinal stem cells initiate intestinal polyposis, Nat. Genet., 39, 189, 10.1038/ng1928 Jemal, 2004, Cancer statistics, 2004, CA Cancer J. Clin., 54, 8, 10.3322/canjclin.54.1.8 Jordan, 2006, Cancer stem cells, N. Engl. J. Med., 355, 1253, 10.1056/NEJMra061808 Kim, 2005, Identification of bronchioalveolar stem cells in normal lung and lung cancer, Cell, 121, 823, 10.1016/j.cell.2005.03.032 Kucia, 2005, Trafficking of normal stem cells and metastasis of cancer stem cells involve similar mechanisms: pivotal role of the SDF-1-CXCR4 axis, Stem Cells, 23, 879, 10.1634/stemcells.2004-0342 Li, 2007, Identification of pancreatic cancer stem cells, Cancer Res., 67, 1030, 10.1158/0008-5472.CAN-06-2030 Loetscher, 2000, Chemokines and their receptors in lymphocyte traffic and HIV infection, Adv. Immunol., 74, 127, 10.1016/S0065-2776(08)60910-4 Matano, 2000, Gemcitabine combined with continuous infusion 5-fluorouracil in advanced and symptomatic pancreatic cancer: a clinical benefit-oriented phase II study, Br. J. Cancer, 82, 1772, 10.1054/bjoc.1999.1139 Moll, 1998, Cytokeratins as markers of differentiation in the diagnosis of epithelial tumors, Subcell. Biochem., 31, 205 Muller, 2001, Involvement of chemokine receptors in breast cancer metastasis, Nature, 410, 50, 10.1038/35065016 O'Brien, 2007, A human colon cancer cell capable of initiating tumour growth in immunodeficient mice, Nature, 445, 106, 10.1038/nature05372 Passegue, 2003, Normal and leukemic hematopoiesis: are leukemias a stem cell disorder or a reacquisition of stem cell characteristics?, Proc. Natl. Acad. Sci. USA, 100, 11842, 10.1073/pnas.2034201100 Peichev, 2000, Expression of VEGFR-2 and AC133 by circulating human CD34(+) cells identifies a population of functional endothelial precursors, Blood, 95, 952, 10.1182/blood.V95.3.952.003k27_952_958 Prindull, 2005, Hypothesis: cell plasticity, linking embryonal stem cells to adult stem cell reservoirs and metastatic cancer cells?, Exp. Hematol., 33, 738, 10.1016/j.exphem.2005.03.002 Ricci-Vitiani, 2007, Identification and expansion of human colon-cancer-initiating cells, Nature, 445, 111, 10.1038/nature05384 Rosenberg, 1997, Treatment of pancreatic cancer. Promises and problems of tamoxifen, somatostatin analogs, and gemcitabine, Int. J. Pancreatol., 22, 81, 10.1007/BF02787465 Rothenberg, 1996, A rationale for expanding the endpoints for clinical trials in advanced pancreatic carcinoma, Cancer, 78, 627, 10.1002/(SICI)1097-0142(19960801)78:3+<627::AID-CNCR7>3.0.CO;2-7 Saur, 2005, CXCR4 expression increases liver and lung metastasis in a mouse model of pancreatic cancer, Gastroenterology, 129, 1237, 10.1053/j.gastro.2005.06.056 Schneider, 2002, Suradista NSC 651016 inhibits the angiogenic activity of CXCL12-stromal cell-derived factor 1{alpha}, Clin. Cancer Res., 8, 3955 Singh, 2004, Identification of human brain tumour initiating cells, Nature, 432, 396, 10.1038/nature03128 Staller, 2003, Chemokine receptor CXCR4 downregulated by von Hippel-Lindau tumour suppressor pVHL, Nature, 425, 307, 10.1038/nature01874 Uchida, 2000, Direct isolation of human central nervous system stem cells, Proc. Natl. Acad. Sci. USA, 97, 14720, 10.1073/pnas.97.26.14720 Warshaw, 1992, Pancreatic carcinoma, N. Engl. J. Med., 326, 455, 10.1056/NEJM199202133260706 Yin, 1997, AC133, a novel marker for human hematopoietic stem and progenitor cells, Blood, 90, 5002, 10.1182/blood.V90.12.5002 Zagzag, 2005, Stromal cell-derived factor-1alpha and CXCR4 expression in hemangioblastoma and clear cell-renal cell carcinoma: von Hippel-Lindau loss-of-function induces expression of a ligand and its receptor, Cancer Res., 65, 6178, 10.1158/0008-5472.CAN-04-4406 Zeelenberg, 2003, The chemokine receptor CXCR4 is required for outgrowth of colon carcinoma micrometastases, Cancer Res., 63, 3833 Zou, 1998, Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development, Nature, 393, 595, 10.1038/31269