Caloric test and video-head-impulse: a study of vertigo/dizziness patients in a community hospital

Andrea Mahringer1, Holger A. Rambold1,2
1Department of Neurology, Community Hospitals Altötting-Burghausen, Altoetting, Germany
2Department of Neurology, University of Regensburg, Regensburg, Germany

Tóm tắt

The head-impulse test (HIT) is an important test for examining unilateral vestibular hypofunction. The new video-head-impulse test (vHIT) is more sensitive and specific than the clinical bedside-head-impulse test (bHIT). Alternatively, one can test for vestibular hypofunction with the caloric irrigation test. Various studies showed that both tests may not always identify vestibular hypofunction; instead, the results of the tests might be contradictory. To evaluate the diagnostic value of these tests, we routinely measured patients exhibiting vertigo or dizziness at our community hospital with bithermal caloric irrigation, the bHIT and the vHIT. Only those patients (n = 172) with a pathological caloric irrigation test of more than 25 % unilateral weakness in the Jongkee’s formula were included. Out of these patients, 41 % had a pathologic vHIT. Among the subgroup with acute symptoms (symptom onset within 5 days), 63 % had a pathological video-head-impulse, whereas only 33 % of the non-acute group (symptom onset more than 5 days) tested pathological. A pathological HIT depended on the disease stage, the amount of unilateral weakness in caloric examination and on the test itself.

Từ khóa


Tài liệu tham khảo

Bhansali SA, Honrubia V (1999) Current status of electronystagmography testing. Otolaryngol Head Neck Surg 120(3):419–426

Halmagyi GM, Curthoys IS (1988) A clinical sign of canal paresis. Arch Neurol 45(7):737–739

Harvey SA, Wood DJ, Feroah TR (1997) Relationship of the head impulse test and head-shake nystagmus in reference to caloric testing. Am J Otol 18(2):207–213

Beynon GJ, Jani P, Baguley DM (1998) A clinical evaluation of head impulse testing. Clin Otolaryngol Allied Sci 23(2):117–122

Weber KP, MacDougall HG, Halmagyi GM, Curthoys IS (2009) Impulsive testing of semicircular-canal function using video-oculography. Ann N Y Acad Sci 1164:486–491. doi:10.1111/j.1749-6632.2008.03730.x

MacDougall HG, Weber KP, McGarvie LA, Halmagyi GM, Curthoys IS (2009) The video head impulse test: diagnostic accuracy in peripheral vestibulopathy. Neurology 73(14):1134–1141. doi:10.1212/WNL.0b013e3181bacf85

Perez N, Rama-Lopez J (2003) Head-impulse and caloric tests in patients with dizziness. Otol Neurotol 24(6):913–917 official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology

Sander T, Machner B, Rambold H, Neumann G, Fritzmannova M, Trillenberg P, Helmchen C (2009) Vertigo: case history and findings on clinical examination. Klin Neurophysiol 40:9

Brandt T (2003) Vertigo: its multisensory syndroms. 2 edn. Springer, London, Berlin, Heidellberg

Committee on hearing and equilibrium guidelines for the diagnosis and evaluation of therapy in Meniere's disease. American Academy of Otolaryngology-Head and Neck Foundation, Inc (1995) Otolaryngology—head and neck surgery. J American Academy Otolaryngol-Head Neck Surg 113(3):181–185

Lempert T, Olesen J, Furman J, Waterston J, Seemungal B, Carey J, Bisdorff A, Versino M, Evers S, Newman-Toker D (2012) Vestibular migraine: diagnostic criteria. J Vestib Res: Equilib Orient 22(4):167–172. doi:10.3233/VES-2012-0453

Best C, Eckhardt-Henn A, Tschan R, Dieterich M (2009) Psychiatric morbidity and comorbidity in different vestibular vertigo syndromes. Results of a prospective longitudinal study over one year. J Neurol 256(1):58–65. doi:10.1007/s00415-009-0038-8

Eckhardt-Henn A, Dieterich M (2005) Psychiatric disorders in otoneurology patients. Neurol clin 23 (3):731–749, vi. doi:10.1016/j.ncl.2005.01.008

Lehnen N, Aw ST, Todd MJ, Halmagyi GM (2004) Head impulse test reveals residual semicircular canal function after vestibular neurectomy. Neurology 62(12):2294–2296

Jorns-Haderli M, Straumann D, Palla A (2007) Accuracy of the bedside head impulse test in detecting vestibular hypofunction. J Neurol Neurosurg Psychiatry 78(10):1113–1118. doi:10.1136/jnnp.2006.109512

Maire R, van Melle G (2006) Diagnostic value of vestibulo-ocular reflex parameters in the detection and characterization of labyrinthine lesions. Otol Neurotol 27(4):535–541. doi:10.1097/01.mao.0000201432.42498.08 official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology

Becker GD (1978) Sources of error in interpretation of caloric tests. Otolaryngology 86 (5):ORL-830–833

Baloh RW, Solingen L, Sills AW, Honrubia V (1977) Caloric testing. 1. Effect of different conditions of ocular fixation. Ann otol Rhinol Laryngol Supp 86(5 Pt 3 Suppl 43):1–6

Feldmann H, Huttenbrink KB, Delank KW (1991) Heat radiation–an essential factor of heat transport in caloric vestibular tests? Current experimental findings. Laryngorhinootologie 70(10):521–531. doi:10.1055/s-2007-998090

Zangemeister WH, Bock O (1979) The influence of pneumatization of mastoid bone on caloric nystagmus response. A clinical study and a mathematical model. Acta Otolaryngologica 88(1–2):105–109

Halmagyi GM, Curthoys IS, Cremer PD, Henderson CJ, Todd MJ, Staples MJ, D’Cruz DM (1990) The human horizontal vestibulo-ocular reflex in response to high-acceleration stimulation before and after unilateral vestibular neurectomy. Exp Brain Res 81(3):479–490

Haque A, Angelaki DE, Dickman JD (2004) Spatial tuning and dynamics of vestibular semicircular canal afferents in rhesus monkeys. Exp Brain Res 155(1):81–90. doi:10.1007/s00221-003-1693-0

Curthoys IS, Halmagyi GM (1999) Vestibular compensation. Adv Otorhinolaryngol 55:82–110

Li H, Dokas LA, Godfrey DA, Rubin AM (2002) Remodeling of synaptic connections in the deafferented vestibular nuclear complex. J Vestib Res 12(4):167–183

Scherer H, Clarke AH (1985) The caloric vestibular reaction in space physiological considerations. Acta Otolaryngol 100(5–6):328–336

Schmid-Priscoveanu A, Bohmer A, Obzina H, Straumann D (2001) Caloric and search-coil head-impulse testing in patients after vestibular neuritis. J Assoc Res Otolaryngol 2(1):72–78

Kirchner H, Kremmyda O, Hufner K, Stephan T, Zingler V, Brandt T, Jahn K, Strupp M (2011) Clinical, electrophysiological, and MRI findings in patients with cerebellar ataxia and a bilaterally pathological head-impulse test. Ann N Y Acad Sci 1233:127–138. doi:10.1111/j.1749-6632.2011.06175.x

Machner B, Gottschalk S, Sander T, Helmchen C, Rambold H (2007) Intralabyrinthine schwannoma affecting the low but not high frequency function of the vestibulo-ocular reflex: implications for the clinical diagnosis of chronic peripheral vestibular deficits. J Neurol Neurosurg Psychiatry 78(7):772–774. doi:10.1136/jnnp.2006.106179

Allison RS, Eizenman M, Tomlinson RD, Nedzelski J, Sharpe JA (1997) Vestibulo-ocular reflex deficits to rapid head turns following intratympanic gentamicin instillation. J Vestib Res 7(5):369–380

Manzari L, Macdougall HG, Burgess AM, Curthoys IS (2012) New, fast, clinical vestibular tests identify whether a vertigo attack is due to early Meniere’s disease or vestibular neuritis. Laryngoscope. doi:10.1002/lary.23479

Maire R, van Melle G (2008) Vestibulo-ocular reflex characteristics in patients with unilateral Meniere’s disease. Otol Neurotol 29(5):693–698. doi:10.1097/MAO.0b013e3181776703 official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology